2015 Fiscal Year Final Research Report
The development of peptide which neutralizes macrophage colony-stimulating factor for inhibition of osteoclastogenesis.
| Project/Area Number |
26861769
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Orthodontics/Pediatric dentistry
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
KIMURA KEISUKE 東北大学, 歯学研究科(研究院), 助教 (70712909)
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Keywords | 破骨細胞 / M-CSF / ペプタイド |
|---|
| Outline of Final Research Achievements |
The recombinant c-fms proteins were inhibited osteoclastogenesis. We used various concentrations of recombinant c-fms proteins (0ng/ml,10ng/ml,100ng/ml,1000ng/ml,10000ng/ml). The effect of inhibition of osteoclastogenesis was dependent on the concentration of recombinant c-fms proteins
|
| Free Research Field |
医歯薬学
|
