2016 Fiscal Year Final Research Report
Elucidation of mechanisms maintaining and regenerating secretory function of water in salivary glands that occurs mastication
| Project/Area Number |
26861774
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthodontics/Pediatric dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 唾液腺 / AQP5 / 咀嚼 |
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| Outline of Final Research Achievements |
We investigated alteration of water secretory function in salivery glands that occurs change and recovery of mastication. In this study, we elucidated that AQP5 was detected on the apical membrane of acinar cells, inter cellular secretory canaliculi of acinar cell in sabmandibular salivary gland in the masticatory hypofunciton group, but the staining appeared to be less prominent than that in the control group. In the masticatory recovery group, expression of AQP5 was observed on that area again. These result.
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| Free Research Field |
歯科矯正学
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