2015 Fiscal Year Annual Research Report
Correlation between brain activity and articulatory movement during speech in cleft lip/palate
| Project/Area Number |
26861776
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
新井 マリステラ小百合 東京医科歯科大学, 医歯(薬)学総合研究科, 非常勤講師 (00707789)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | cleft lip and palate / fMRI / MRI movie / overt articulation / covert articulation |
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| Outline of Annual Research Achievements |
The overall goal of this study was undertaken to demonstrate the importance of the versatile evaluation of articulatory function in cleft lip and palate (CLP) from central and peripheral perspectives.
Following results were obtained: using 3D MRImovie, the articulatory movements in the midsagittal, horizontal and coronal planes were observed in a volumetric image of the 3-D MRI movie. Visualizing the articulation in sagittal plane the dorsum of tongue elevate to contact the palate and the soft palate elevate move backward contacting the posterior pharyngeal wall to produce the consonant sound of /k/. At the same time, the lips contact during rest on coronal view and during horizontal view the lateral and posterior pharyngeal wall were practically unmoving in health volunteers. However in CLP patient with compensatory misarticulation (CMA) those movements differ, the tongue don’t elevate to produce the consonant, but move backward, the soft palate present short length and the lateral and posterior pharyngeal wall present a compensatory movement to produce the velopharyngeal closure; besides using fMRI technique, in the overt task (O-task), motor-related areas including the premotor and primary sensorimotor cortices and the cerebellum were activated in CLP participants without CMA, which generally resembled the activation patterns in healthy participants, however the activation patterns for articulation was different between CLP subjects with CMA. In the covert task (C-task), there were no significant differences in the activation patterns between participants.
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Research Products
(3 results)
