Clinical application of real time brain functional mapping by electrocorticography.

2015 Fiscal Year Final Research Report

• Project/Area Number: 26870024
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Brain biometrics; Neurosurgery
• Research Institution: Asahikawa Medical College
• Principal Investigator: OGAWA Hiroshi 旭川医科大学, 医学部, 助教 (60632536)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: Electrocorticogram / High gamma activity / Epilepsy focus

Outline of Final Research Achievements

High gamma activity (HGA) ranging between 60 and 120 Hz on electrocorticogram (ECoG) is assumed to reflect localized cortical processing. In this study, we used real time ECoG mapping for rapid and reliable identification of motor and language functions. Ten with epilepsy and 13 who underwent awake craniotomy participated in this study. We performed ECoG during hand motor and language tasks using subdural grids and obtained HGA (60-170 Hz) maps in real time. The results were compared and calculated to assess the sensitivity and specificity of HGA mapping. The mapping results were highly accurate in both patients with epilepsy and those who underwent awake craniotomy. In addition, there were no statistical differences between the 2 groups. Real-time HGA mapping allowed rapid, accurate and low-invasive detection of motor and language functional areas.

Free Research Field

医歯薬学　総合領域