2015 Fiscal Year Final Research Report
Investigation of the transcription factors to control the function and development of basophils.
| Project/Area Number |
26870172
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Experimental pathology
Immunology
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| Research Institution | Chiba University |
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Principal Investigator |
NINOMIYA Kazusige 千葉大学, 医学(系)研究科(研究院), 特任助教 (20706999)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Keywords | 転写因子 / アレルギー / 免疫 / 寄生虫感染症 |
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| Outline of Final Research Achievements |
There are many patients suffering from various allergic diseases in developed countries. The effective drugs are desired to improve the quality of life of the patients. Recently, it has been revealed that basophils play an important role in develop and maintenance of these allergic diseases. In this study, we identified the transcription factor GATA-1 controls the differentiation and function of basophils. This study opens up the possibility that GATA-1 may be a therapeutic target for allergic diseases.
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| Free Research Field |
医歯薬学
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