2015 Fiscal Year Final Research Report
Exploration of ATP signaling molecules involved in progression of pancreatic cancer
| Project/Area Number |
26870874
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Tumor biology
Gastroenterology
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| Research Institution | National Cancer Center Japan |
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Principal Investigator |
Takai Erina 国立研究開発法人国立がん研究センター, 研究所, 特任研究員 (90723891)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Keywords | 膵臓がん / ATPシグナリング / 転移 |
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| Outline of Final Research Achievements |
Extracellular nucleotides, such as ATP, play roles in various physiological and pathological processes through activation of P2 receptors. Although many cancer cells express ATP signaling molecules, their involvement in cancer progression has not been fully understood. In this study, we investigated importance of ATP signaling in pancreatic cancer progression and proposed that ATP signaling molecules including P2X7 could play a role in metastasis of pancreatic cancer.
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| Free Research Field |
腫瘍学
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