An implantable neural bidirectional device for behavior experiments of small animals

2015 Fiscal Year Final Research Report

• Project/Area Number: 26882027
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Brain biometrics
• Research Institution: Nara Institute of Science and Technology
• Principal Investigator: Haruta Makito 奈良先端科学技術大学院大学, 物質創成科学研究科, 博士研究員 (40733663)
• Project Period (FY): 2014-08-29 – 2016-03-31
• Keywords: CMOSイメージセンサ / 脳機能イメージング / 脳血流計測 / オプトジェネティクス / 生体埋植デバイス / 多点光刺激

Outline of Final Research Achievements

We have developed an implantable neural bidirectional device for understanding brain functions in behavior experiments of small animals. This device has two functions which are optically detecting and controlling brain activities. In this study, we achieved the following results; (1) The device weights about 0.2 g which is much lighter than the weight of an adult mouse. (2) The device detected brain activities in the smart somatosensory cortex when the frontal limb was stimulated. (3) The device controlled brain activities using multi optical stimulations in a brain of channelrhodopsin2-NestinCre transgenic mice.

Free Research Field

脳計測学