the effect of high intensity exercise on metabolic response in skeletal muscle

2015 Fiscal Year Final Research Report

• Project/Area Number: 26882048
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Applied health science
• Research Institution: Niigata University of Health and Welfare
• Principal Investigator: Masuda Hiroyuki 新潟医療福祉大学, 健康科学部, 助手 (10738561)
• Project Period (FY): 2014-08-29 – 2016-03-31
• Keywords: 骨格筋 / 代謝適応 / ラット / 高強度運動 / Akt

Outline of Final Research Achievements

Activation of AMPK is involved in the muscle metabolic response to lactate threshold intensity (LT) exercise. Furthermore, low-volume high intensity exercise is rapid metabolic responses in muscle that are comparable to following LT exercise. Our study aimed to examine the possibility that muscle metabolic response induced by high intensity exercise is mediated by the activation of Akt. However, Akt (Thr308) is activated by LT exercise. In addition, AMPK is activated by below LT exercise because phosphorylation of ACC (Ser79) measured by a commonly used indicator of AMPK is activated by below LT exercise.

Free Research Field

運動生理生化学