2015 Fiscal Year Final Research Report
Research for pharmacological activity of gold nanocluster for a new anticancer agent
| Project/Area Number |
26886012
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Nanobioscience
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| Research Institution | Tokyo Metropolitan University |
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Principal Investigator |
Fujita Takashi 首都大学東京, 都市環境科学研究科, 特任助教 (30737565)
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| Project Period (FY) |
2014-08-29 – 2016-03-31
|
| Keywords | 金クラスター / 細胞毒性 / ナノ毒性 |
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| Outline of Final Research Achievements |
Cytotoxicity of oxide-supported gold nanoparticulate catalysts toward cancer cell lines were investigated. Among the investigated catalysts (Au/SiO2, Au/TiO2, Au/Fe2O3, Au/ZnO, and Au/ZrO2), Au/ZnO showed high cytotoxicity for HeLa and Mia Paca-2. Although simple ZnO also exhibits relatively high cytotoxicity compared to other oxides, this cytotoxicity further increased by deposition of gold nano clusters.
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| Free Research Field |
触媒化学、分析化学
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