2015 Fiscal Year Final Research Report
Chemical studies on novel purine metabolic pathway of fairy chemicals
| Project/Area Number |
26892013
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Bioorganic chemistry
|
|---|
| Research Institution | Shizuoka University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-08-29 – 2016-03-31
|
| Keywords | 天然物化学 / 代謝産物 / フェアリー化合物 |
|---|
| Outline of Final Research Achievements |
Fairy chemicals that cause fairy ring, 2-azahypoxanthine (AHX) and imidazole-4-carboxamide (ICA), were isolated form Lepista sordida. In plant, AHX were existed and metabolized to 2-aza-8-oxohypoxanthine (AOH). We examined the endogenous fairy chemicals in microorganisms. AHX and AOH were detected in plants and fungi. The metabolites of ｆairy chemicals in the plant were isolated, and then determined the structures. Currently, we are trying to identify the biosynthesis and metabolism enzymes. The yield increased production effect on the crop of AHX. An efficient AOH synthesis using resting cells was studyed.
|
| Free Research Field |
農学
|
