2015 Fiscal Year Final Research Report
Elucidation of the pain disorder onset with depression model rat
| Project/Area Number |
26893084
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| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
|
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| Research Institution | Niigata University |
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Principal Investigator |
|
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| Project Period (FY) |
2014-08-29 – 2016-03-31
|
| Keywords | 疼痛性障害 / うつ病 / セロトニン / 神経ペプチド |
|---|
| Outline of Final Research Achievements |
Using a depression model rat, in order to elucidate the neural mechanisms of depression-related type pain disorder, escape behavior analysis by behavioral experiments, anti-depressants for the electrophysiological analysis and pain disorders of neural activity that are involved in pain central of medicine and tried to analysis of peripheral pharmacological action. In addition, related pain disorders and brain serotonin decrease, the presence of the neuropeptides that affect the peripheral receptors to receive the pain, was studied relief of pain disorders due to the increase in brain serotonin.
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| Free Research Field |
歯科矯正学
|
