2015 Fiscal Year Final Research Report
The effect of farnesyltransferase inhibitor on acute liver dysfunction
| Project/Area Number |
26893193
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Anesthesiology
|
|---|
| Research Institution | Kyushu University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-08-29 – 2016-03-31
|
| Keywords | farnesytransferase |
|---|
| Outline of Final Research Achievements |
This study revealed that farnesyltransferase inhibitor have the effect of hepatoprotective action for local acute liver failure. Specifically, with a mouse acute liver failure model, the inflammation reaction in the liver attenuated by the farnesyltransferase inhibitor and improved a survival rate.
|
| Free Research Field |
anesthesiology
|
