2015 Fiscal Year Final Research Report
A combination of low-intensity pulsed ultrasound and nanohydroxyapatite concordantly enhances osteogenesis of adipose-derived stem cells from buccal fat pad
| Project/Area Number |
26893272
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Showa University |
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Principal Investigator |
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| Research Collaborator |
SHIROTA Tatsuo 昭和大学歯学部, 口腔外科学講座 顎顔面外科学部門 (60235760)
KONDO Seiji 昭和大学歯学部, 口腔外科学講座 顎顔面外科学部門 (10432634)
MUKUDAI Yoshiki 昭和大学歯学部, 口腔外科学講座 顎顔面外科学部門 (50325099)
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| Project Period (FY) |
2014-08-29 – 2016-03-31
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| Keywords | 再生医療 / 骨 / 脂肪幹細胞 |
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| Outline of Final Research Achievements |
That adipose-derived stem cells from buccal fat pad recognize the bone regeneration for bone defects, in order to clarify to admit a synergistic effect by further NHA (nano-hydroxyapatite) was added and LIPUS (Low Intensity Pulsed Ultrasound) irradiation in combination, discussed intentionally fabricated bone defect model animal, the degree of new bone was immunohistochemical quantitative evaluation.
As a result, were subjected to immunohistochemical analysis, regeneration of new bone by adipose-derived stem cells from buccal fat pad was observed. Further, it was possible to find more dominant bone augmentation by combining the NHA added and LIPUS irradiation.
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| Free Research Field |
再生医療
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