2015 Fiscal Year Final Research Report
investigation of mechanism of alveolar bone development and regeneration through analysis of TRPM7, bone mineral transporter.
| Project/Area Number |
26893319
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Fukuoka Dental College |
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Principal Investigator |
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| Project Period (FY) |
2014-08-29 – 2016-03-31
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| Keywords | 歯学 |
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| Outline of Final Research Achievements |
The main aim of this research is investing the mechanism of alveolar bone development and new bone formation induced by bone regeneration therapy through analysis focused on TRPM7 and generating more effective bone regeneration therapy. TRPM7 is calcium ion and magnesium ion permeable cation ion channel, transports minerals and also contains alpha kinase domain that has various physiological effects. In this research, we estimated the effect of TRPM7 on tibia and alveolar bone properties through in vivo and in vitro experiments using alpha kinase domain mutant mice.
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| Free Research Field |
歯学
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