1986 Fiscal Year Final Research Report Summary
Development of New Ionizations Technique such as SIMS, FAB and FD and Mass Spectrometry of Biomedical Substance.
| Project/Area Number |
59390017
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| Research Category |
Grant-in-Aid for Co-operative Research (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
広領域
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| Research Institution | College of General Education, Osaka University |
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Principal Investigator |
MATSUDA Hisashi Osaka University, 教養部, 教授 (50029592)
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| Co-Investigator(Kenkyū-buntansha) |
MATSUO Takekiyo Osaka University, 教養部, 助教授 (50029691)
YAMAMOTO Masao Nara Women's University, 理学部, 教授 (80028159)
OKANO Jun Osaka University, 教養部, 教授 (10028087)
OHASHI Mamoru The University of Electrocommunications, 電気通信学部, 教授 (70015535)
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| Project Period (FY) |
1984 – 1986
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| Keywords | SIMS / FAB / FD / Mass Spectrometry / Soft Ionization / Peptide / Cluster Ion / イオンガン |
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| Research Abstract |
1. Mass Spectrometry of Biomedical Highmass Substance
In beam technique was introduced by Ohashi. The behaviour of Na ion in the SIMS ionization was investigated by Suzuki. Matsuo, Katakuse and Matsuda established the technique to analyze the hemoglobin variants, and determined several new structure of variants. They also measured the mass distribution in the mass spectrum of peptide. Ikekawa investigated the method of sample preparation.
2. Ion Source
A liquid ion source was developed by Tsuchiya. Noda developed an electron bombardment type micro ion source. Okuyama improved ion emitters for FD ionization.
3. Ionization Mechanism
Theoretical study of electron impact ionization was carried out by Yamamoto. Nakata studied the ionization mechanism of proton attachment.
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