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1986 Fiscal Year Final Research Report Summary

Development of New Ionizations Technique such as SIMS, FAB and FD and Mass Spectrometry of Biomedical Substance.

Research Project

Project/Area Number 59390017
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field 広領域
Research InstitutionCollege of General Education, Osaka University

Principal Investigator

MATSUDA Hisashi  Osaka University, 教養部, 教授 (50029592)

Co-Investigator(Kenkyū-buntansha) MATSUO Takekiyo  Osaka University, 教養部, 助教授 (50029691)
YAMAMOTO Masao  Nara Women's University, 理学部, 教授 (80028159)
OKANO Jun  Osaka University, 教養部, 教授 (10028087)
OHASHI Mamoru  The University of Electrocommunications, 電気通信学部, 教授 (70015535)
Project Period (FY) 1984 – 1986
KeywordsSIMS / FAB / FD / Mass Spectrometry / Soft Ionization / Peptide / Cluster Ion / イオンガン
Research Abstract

1. Mass Spectrometry of Biomedical Highmass Substance
In beam technique was introduced by Ohashi. The behaviour of Na ion in the SIMS ionization was investigated by Suzuki. Matsuo, Katakuse and Matsuda established the technique to analyze the hemoglobin variants, and determined several new structure of variants. They also measured the mass distribution in the mass spectrum of peptide. Ikekawa investigated the method of sample preparation.
2. Ion Source
A liquid ion source was developed by Tsuchiya. Noda developed an electron bombardment type micro ion source. Okuyama improved ion emitters for FD ionization.
3. Ionization Mechanism
Theoretical study of electron impact ionization was carried out by Yamamoto. Nakata studied the ionization mechanism of proton attachment.

Research Products

(22 results)

All Other

All Publications (22 results)

  • [Publications] H.Ohashi;T.Tsurushima;T.Ueno;H.Fukami: Agric.Biol.Chem.50(10). 2655-2657 (1986)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] l.Katakuse;T.Ichihara;Y.Fujita;T.Matsuo;T.Sakurai;H,Matuda: Int.J.Mass SPectrom.and Ion Proc.67. 229-236 (1985)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Y.Fujita;T.Matsuo;T.Sakurai;H.Matsuda;I.Katakuse: Int.J.Mass Spectrom.and Ion Proc.63. 231-240 (1985)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] I.Katakuse;T.Ichihara;H.Nakabushi;T.Matsuo;H.Matsuda: Mass Spectroscopy. 31. 111-114 (1983)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Noda;T.Okutani;H.Tamura: J.Appl.Phys.54(9). 935-939 (1985)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.Takatsuto;N.Ikekawa: Chem.Pharm.Bull.34(8). 3435-3439 (1986)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Takeuchi;S.Ueno;M.Yamamoto;T.Matsushita;K.Nishimoto: Int.J.Mass.Spectrom.and Ion Proc.64. 33-48 (1985)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] M.Ohashi;H.Iino;K.Tsujimoto;Y.Ohashi;Y.Shida: Org.Mass Spectrometery. 20(10). 642-643 (1985)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] J.Okano;T.Ochiai;H.Nishimura: Application of Surface Science. 22/23. 72-81 (1985)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.Harada;I.Kimura;K.Matsuda;M.Suzuki: Org.Mass Spectrometry. 20(9). 582-588 (1985)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.Nakata;Y.Hosino;N.Takeda;A.Takematsu: Org.Mass Spectrometry. 20(7). 467-470 (1985)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] M.Tsuchiya H.Kuwabara: Anal.Chem.56. 14-19 (1984)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H. Ohashi, T. Tsurushima, T. Ueno and H. Fukami: "Cerbinal, a Pseudoazulene Iridoid, as a Potent Anitifungal Compound Isolated from Gradenia Jaminoides Ellis." Agric. Biol. Chem.50(10). 2655-2657 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] I. Katakuse, T. Ichihara, Y. Fujita, T. Matsuo, T. Sakurai and H. Matsuda: "Mass Distributions of Copper, Silver and Gold Clusters and Electronic Shell Structure." Int. J. Mass Spectrom. and Ion Proc.67. 229-236 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Y. Fujita, T. Matsuo, T. Rakurai, H. Matsuda and I. Katakuse: "Mass Distribution of Peptide Molecular Ion in the Secondary Ionization Process." Int. J. Mass Spectrom. and Ion Proc.63. 231-240 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] I. Katakuse, T. Ichihara, H. Nakabushi, T. Matsuo and H. Matsuda: "A Compact Primary Gun for Molecular SIMS" Mass Spectroscopy. 31. 111-114 (1983)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] T. Noda, T. Okutani and H. Tamura: "Electron Bombardment Type Micro Ion Source." J. Appl. Phys.54(9). 935-939 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S. Takatsuto and N. Ikekawa: "Analysis of 2-Deoxybrassinoteroids by Gas Chromatography-Mass Spectrometry" Chem. Pharm. Bull.34(8). 3435-3439 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] T. Takeuchi, S. Ueno, M.Yamamoto, T. Matsushita and K. Nishimoto: "Theoretical Study of Electron Impact Mass Spectrometry. <II> . AB Initio Mo Study of The Fragmentation of Ionized 1-Propanol." Int. J. Mass Spectrom. and Ion Proc.64. 33-48 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] M. Ohashi, H. Iino, K. Tsujimoto, Y. Ohashi and Y. Shida: "In-beam Electron Impact Mass Spectrometry of Phosphatidylcholines. A Convenient Method for Positional Isomer Discrimination." Org. Mass Spectrometry. 20(10). 642-643 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] J. Okano, T. Ochiai and H. Nishimura: "Ion-Beam-Induced Isotope Composition Changes in Metal Surfaces and Recoil Implantation." Application of Surface Science. 22/23. 72-81 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] K. Harada, I. Kimura, K. Matsuda and M. Suzuki: "Structural Investigation of the Antibiotic Sporaviridin 11-Molecular Secondary Ion Mass Spectral Studies on the Constituent Pentasaccharides Viridopentaoses." Org. Mass Spectrometry. 20(9). 582-588 (1985)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1988-11-08  

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