1985 Fiscal Year Final Research Report Summary
Studies regarding nutritional composition in enteral and parenteral nutrition in infants.
| Project/Area Number |
59440055
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| Research Category |
Grant-in-Aid for General Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
General surgery
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| Research Institution | Juntendo University |
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Principal Investigator |
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| Project Period (FY) |
1984 – 1985
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| Keywords | 経腸栄養 / 非経腸栄養 / 高カロリー輸液 / 完全静脈栄養 / 乳児 / 消費熱量測定 |
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| Research Abstract |
1. Enteral nutrition (1) An experimental study using Thiry-Vella loop of weaning rats suggested that small peptides as a nitrogen source in Chemically Defined Diet have nutritional advantages especially in the youngers.
(2) Experimental and clinical studies revealed that an emulsified fat ingredient was useful as a fat module in enteral nutrition.
2. Parenteral nutrition (1) Amount and composition of amino acids mixture in total parenteral nutrition ( TPN ) in neonates.
A. Clinical studies of TPN in 360 neonates indicated that the recommended allowance of amino acids in TPN with commercial amino acids mixture migth be 1.5 - 2.5g/kg/day in neonates and young infants.
B. A study of plasma aminogram in neonates with TPN using a newly devised amino acids mixture ( Nl-2 ) presented the revised composition of Nl-2 ( Nl-3 ) for parenteral use in neonate and young infants.
(2) Amino acids mixture for parenteral nutrition in infants with obstructive hepatic dysfunction.
A. A study of plasma aminogram during TPN in weaning rats with obstructive iaundice revealed that there might be more suitable amino acids composition for parenteral use in the subjects with hepatic impairment.
B. A study of plasma aminogram in infants with biliary atresia proposed a newly devised amino acids mixture for the parenteral nutrition ( NlH-1 ).
3. The development of a computerized calorimetry
indirect calorimetry using a canopy hood is the most reliable for determining the energy needs of patients. it gives patients great comfort and facilitates metabolic monitoring even in infants. The room air flow into the canopy is set at the volume of the canopy plus five times the value of the minute-ventilation of the subject; this prevents <CO_2> rebreathing and produces a sufficient change in <CO_2> concentration for accurate resolution.
This system allows for accuracy, portability, and rapid manipulation of the data.
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