1987 Fiscal Year Final Research Report Summary
Long-term follow-up of dual A-V nodal pathways and electrophysiological determinants in the development of A-V nodal reentrant tachycardia
| Project/Area Number |
60480234
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Nakasaki University |
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Principal Investigator |
HASHIBA Kunitake Nagasaki Univ. School of Med., Professor, 医学部, 教授 (40039483)
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| Co-Investigator(Kenkyū-buntansha) |
YANO Katsusuke nagasaki Univ. School of Med., Assistant Professor, 医学部, 講師 (50039864)
KIYA Fumihiro Nagasaki Univ. School of Med., Medical Associate, 医学部, 助手 (20108301)
FUKATANI Masahiko Nagasaki Univ. School of Med., Assistant Professor, 医学部, 講師 (70039551)
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| Project Period (FY) |
1985 – 1987
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| Keywords | dual A-V nodal pathways / 発作性上室性頻拍 / 経年的変化 / 臨床心臓電気生理検査 / 経食道心房ペーシング法 / 心房期外刺激法 |
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| Research Abstract |
The dual A-V nodal pathways (DAVNPW) are one of the important mechanism of the paroxysmal supraventricular tachycardia (A-V modal reentrant tachycardia) and have been considered ad a functional longitudinal dissociation within the A-V node rather than anatomical abnormalities. The purpose of this study is to study the reproducibility of DAVNPW in a ong follow-up period to clarify the peroperties of DAVNPW and to study the electrophysiological determinants of A-V nodal reentry.
Subjects were 499 patients in whom electrophysiologic studies (EPS) were performed for various cardic arrhythmias between 1975 and 1984. DAVNPW were observed in 120 (24.0%) of the 499 patients. The electrophysiological properties of antegrade and retrograde pathways of DAVNPW were analyzed in 54 of the 120 patients. The A-V nodal reentrtant tachycardia was induced more frequently in patients in whom both antegrade and retrograde Wenckebach points were 150 neats/min or more. In 18 out of the 120 patients with DAVNPW the 2nd EPS was performed using moninvasive transesophageal pacing method. DAVNPW were reconfirmed to exist in 16 (88.9%) of 1, patients after 6 - 104 (average 40) months of the initial EPS. The width of jump from the fast to slow pathways, and ERP and FRP of the fast and slow pathways in the 2nd study were significantly correlated with those in the 1st study, respectively.
These results suggest that DAVNPW might be more likely related to some structural rather than purely functional abnormalities and that patients with excellent conductivity both antegrade slow pathway and in retrograde fast pathway are more likely to have A-V nodal reentrant tachycardia.
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Research Products
(9 results)
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[Publications] 深谷眞彦, 山崎英文, 香江篤, 木村幹史, 森光弘, 谷川宗生, 植山千秋, 北野幸英, 木谷文博, 矢野捷介, 橋場邦武: 第49回日本循環器学会総会(Jpn Circul J). 49. 818 (1985)
Description
「研究成果報告書概要(和文)」より
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