1986 Fiscal Year Final Research Report Summary
Sero-epidemiological Study of Herpes Simplex Virus
| Project/Area Number |
60570259
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
公衆衛生学
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| Research Institution | Yokohama City University |
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Principal Investigator |
SODA Kenji Yokohama City University School of Medicine, 医学部, 教授 (80154706)
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| Co-Investigator(Kenkyū-buntansha) |
ICHIKAWA Seiichi Yokohama City University School of Medicine, 医学部, 助手 (90106302)
MURABAYASHI Hiroshi Yokohama City University School of Medicine, 医学部, 助手 (00046153)
TOBA Masanori Yokohama City University School of Medicine, 医学部, 助教授 (50012753)
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| Project Period (FY) |
1985 – 1986
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| Keywords | Herpes simplex virus / Sero-epidemiology / neutralizing antibody / antibody prevalence in age groups / antibody prevalence in medical staffs / 抗体陽転率 |
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| Research Abstract |
A sensitive and reproducible micro-method to assay neutralizing antibodies against herpes simples virus(HSV) was established for analyzing antibody prevalence of HSV in normal population and in medical staffs.
The results obtained by assaying 490 normal serum samples and 544 sera of medical personnel were summarized as follows:
1. Antibody positive rate to HSV in 10-30 years-old population was low when compared with those of former reports carried out in 1962, 1973, and 1974.
2. Concerning medical personnel, antibody prevalence was apparently low in doctors compared with that of controls in all age groups, but that of nursing staffs was slightly higher in general and this tendency was remarkable in a group aged 20-24 years.
3. Eighteen-months follow-up was carried out in 177 nurses taking samples 2 or 3 times 6 to 12 months apart. Seroconversion was observed only in the group aged 20-29 years, and the conversion rate(3.4 %) was significantly higher than that of control population calculated from the value of sero-positive rate.
These data indicate that young medical personnel, especially nurse, might be identified as one of risk groups of HSV infection as a result of lowered prevalence of antibody in a young adult population.
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Research Products
(6 results)
