1987 Fiscal Year Final Research Report Summary
A study of measurements of electrical bio-impedance in breast tumors
| Project/Area Number |
60570592
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
General surgery
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| Research Institution | The University of Tokushima |
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Principal Investigator |
TADAOKI Morimoto School of Medicine, lecturer, 医学部附属病院第二外科, 講師 (10112244)
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| Co-Investigator(Kenkyū-buntansha) |
TADAMITSU Iritani Technical College of Tokushima University, assistant professor, 工業短期大学部電子工学科, 助教授 (60035813)
YOHSUKE kinouchi Faculty of Engineering, assistant professor, 工学部電気工学科, 助教授 (80035807)
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| Project Period (FY) |
1985 – 1987
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| Keywords | breast tumor / electrical property / bio-impedance / 診断法 |
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| Research Abstract |
For the purpose of applying the differences in electric properties of tissue to the diagnosis of tumors, the electrical bio-impedance of 54 patients with breast tumors were measured. A new impedance analyzer system was developed and the mesurements were perforemed within the frequency range of 0 to 200 kHz with three-electrode method. The three-electrode consists of a coaxial needle electrode inserted into the tumor and a large reference on upper abdominal wall. The living tissue can be regarded electorically as a equivalent consisted of extracellular resistance(R1), intracellular resistance(R2), and electric capacitance of the cell membrance(C). These three parameters were calculated from the measured values of electrical bio-impedance. It was found that R1 and R2 of breast cancers were significantly higher than those of benign tumors (p<0.01), and that C of breast cancers was significantly lower than that of benign tumors (p<0.01). The measurement of electrical bioimpedance of breast tumor may be appliedc to the differencial diagnosis of breast lesions.
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