• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

1988 Fiscal Year Final Research Report Summary

Study of the function and differentiation of folliculo-stellate cell in anterior pituitary gland.

Research Project

Project/Area Number 61570003
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field General anatomy (including Histology/Embryology)
Research InstitutionGunma University

Principal Investigator

INOUE Kinji  Gunma University, Institute of Endocrinology, 内分泌研究所, 助教授 (50091963)

Project Period (FY) 1986 – 1988
KeywordsANTERIOR PITUITARY / STRIATE MUSCLE / FOLLICULO*STELLATE CELL / フィブロネクチン / 筋繊維
Research Abstract

In order to reveal the function and differentiation of folliculo-stellate cell in the rat anterior pituitary gland, the morphological studies were performed. The main finding of this study was the observation of striated muscle fibers in the pituitary gland grafts transplanted beneath the kidney capsule. These ectopic differentiated striated muscle fibers were closely associated with folliculo-stellate cells, including the possibility of folliculo-stellate cell have a potential of differentiation to striated muscle fibers.
The histochemical studies revealed that follicul/-stellate cell have extremely elongated cell processes which wrap around the neighboring glandular cells. Ca-depend ATPase localized around these cell processes and follicle lumen, suggesting folliculo-stellate cell may control the secretory function of neighboring glandular cells through the regulation of calcium transport. the immunohistochemical studies revealed that folliculo-stellate cell contain fibronectin however, the biological significance of fibronectin in folliculo-stellate cell is unknown.
In conclusion, it is considered that folliculo-stellate cell is a multi-functional cell which control the neighboring glandular cell in anterior pituitary gland.

  • Research Products

    (13 results)

All Other

All Publications (13 results)

  • [Publications] K.Inoue.: Arch.histol.Jap.50. 567-578 (1987)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 井上金治: 脳腸ホルモン学会ニュース. 2. 24-27 (1987)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 井上金治: 病態生理. 8. 75-78 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Sakai.: Endocrinology. 122. 2803-2808 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.Kato.: Mol.Cell.Endoc.62. (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Y.C.Liu.: Histochemistry. (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.Inoue.: "Electron microscopic studies on the structure and function of folliculo-stellate cells in the ratanterior pituitany(Proc,6th M.Synger Symposium)" S.Inoue, 565-576 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] INOUE K.: "Differentiation of striated muscle fibers in pituitary gland grafts transplanted beneath the kidney capsule." Arch. histol. jap.50. 567-578 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] SAKAI T.: "Effect of passive immunization to gonadotropin-releasing hormone (GnRH) using GnRH antiserum on the mitotic activity of gonadotrophs in castrated male rats." Endocrinology. 122. 2803-2808 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] KATO K: "Simultaneous effect of gonadotropin-releasing hormone (GnRH) on the expression of two gonadotropin genes by passive immunization to GnRH." Mol. Cell Endoc.62. 47-53 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] LIU Y.C.: "Localization of fibronectin in the folliculo-stellate cells of the rat anterior pituitary by the double bridge peroxidase-antiperoxidase method." Histochemistry. in print. (1989)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] INOUE K.: "Regulation of cell proliferation of gonadotrophs in castrated rat anterior pituitary." Proceedings of 8th International Congress of Endocrinology. (1988)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] INOUE K.: Electron microscopic stuies on the structure and function of folliculo-stellate cells in the rat anterior pituitary.Okada Printing and publishing CO., Maebashi, 565-576 (1988)

    • Description
      「研究成果報告書概要(欧文)」より

URL: 

Published: 1990-03-20  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi