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1987 Fiscal Year Final Research Report Summary

Studies on the calcification mechanism of enamel using ion-selective membrane and glass fiber

Research Project

Project/Area Number 61570871
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Morphological basic dentistry
Research InstitutionAsahi University School of Dentistry

Principal Investigator

MORIWAKI Yutaka  Asahi Unveristy School of Dentistry ; Professor, 歯学部, 教授 (90028738)

Co-Investigator(Kenkyū-buntansha) GOTO Ytakayasu  Asahi University School of Dentistry ; Lecturer, 歯学部, 講師 (30121320)
DOI Yutaka  Asahi University School of Dentistry ; Associate Professor, 歯学部, 助教授 (40116067)
YOSHIDA Sadahiro  Asahi University School of %dentistry ; Professor, 歯学部, 教授 (40076005)
Project Period (FY) 1986 – 1987
KeywordsCalcification / Enmel apatite / Apatite synthesis / Hydroxyapatite / Octacalcium phosphate / Crystal nucleation / Crystal growth
Research Abstract

Cation-delective membrtance were used as a model cell for tissue cell to get better understanding of calcification mechanism in tooth enamel. Our previous in vitro finding has suggested that hydroxyapatite obtained by hydrolysis of octacalcium phoshate that nucleated on and grew perpendicular to the cation-selective membrane id comparable to human enamel in respect to crystal shape,crystallinity and the degree od orientation.
In this report,the influenece of pH and initial concentrations of calcium,phosphate, carbonate,magnesium and fluoride ions on the morphology and orientation of octacalcium phosphate is stafued in the cation-selective membrane system and glass-fiber system to elecidate the calcification mecanism and growrh process in enamel. In order to clarify the reaction that might ge taking place in the diffusion layer on the cation-selective membrane, some reactions were carried out in non-membrane sytem in which precipitation was initiated by adding calcium solution fropwise t … More o phosphate solution. In the membrane system, initial precipitated on the membrane appeared granular in shape and the incresed in size to from a co-agulated granular form, resulting in a creat-like appeatanece. With time, however, they grew outbawd prefetentially perpenficular to the membrance, of which X-tby diffraction pattern was characteristic of oriented OCP.
In the non-membrance system, the first precipitation took place when the solution saturtation was slightly undersaturated with respect to reported value of ACP solubility product. Interesting point was that when continued the Ca addition the degree of solution saturation moved alog almost parallel to the solubility line of OCP the chemical potential plot. But, once the Ca addition ceased OCP convert to hydroxyapatite. From these in vitro findings it may behypothsized that in enemel formation feeding rate of Ca^<2+> to mineralixaing fornt is modetrately greater enough to stabilize fibbon-kike COP and enemel prisms might be formwd. %on the contray, in the calcification of bone and dentine the Ca^<24> feeding rate may bre consiferably smaller. Less

  • Research Products

    (2 results)

All Other

All Publications (2 results)

  • [Publications] M.Iijima;Y.Moriwaki et al.: Calcified Tissue International. 41. (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] M. Hata et al.: Elsevier Science Publish Inc.Formation of highly oriented apatite on cation-selective membrane at physiological temperature and pH ( in Tooth Enamel IV ), 37-41 (1984)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1989-03-30  

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