1987 Fiscal Year Final Research Report Summary
Development of the system for extracorporeal stone disintegration using microexplosion;Disintegration of renal and gall stone.
| Project/Area Number |
61870061
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| Research Category |
Grant-in-Aid for Developmental Scientific Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Urology
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| Research Institution | TOHOKU UNIVERSITY |
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Principal Investigator |
KUWAHARA Masa-aki Department of Urology, Tohoku University School of Medicine, 医学部, 助教授 (50006780)
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| Co-Investigator(Kenkyū-buntansha) |
IINUMA Kazuhiro Tohsiba Co. Ltd., 研究所長
大川 俊之 八千代田工業(株), 研究員
ISE Hideo Department of Surgery Tohoku University School of Medicine, 医学部附属病院, 助手 (10150260)
KAGEYAM Shizuichi Department of Urology Tohoku Univerfsity School of Medicine, 医学部附属病院, 助手 (10160996)
TAKAYAMA Kazuyoshi Institute of High Speed Mechanics, Tohoku Univerfsity, 高速力学研究所, 教授 (40006193)
OHKAWA Toshiyuki Yachiyoda Industry Co.Ltd.
HOSOYA Fumio Hosaya Kako Co. Ltd.
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| Project Period (FY) |
1986 – 1987
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| Keywords | Underwater shock wave / Microexplosion / Explosion / Kidney calculus / Gall stone / extracorporeal stone disintegration / ESWL |
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| Research Abstract |
We have developed the extracorporeal shock wave lithotriper using chemical explosives(silver azide, 10mg) as an energy source of shock wave generation. This method(mESWL) was applied clinically since March 1985. Up to may 1987 a total of 229 cases was treated with 96% of clinical success rate. Renal function estimated by 99mTC-dimercaptosuccinic acid renal uptake-rate revealed no sighnificant deleterious effect on the renal function. As the complication, 1 case of bactgeremia, 1 case of gastro-intestinal bleeding and 2 cases of subcapsular renal hematoma were observed. The occurrence rate of complication was almost equivalent to Dornier System. All these complicated cases were Lreated conservatively, except 1 case of percutaneous drainage in the subcapsular hematomas. The results indicated that mESWL is safe and effective for the tratment on the upper urinary tract calculi. We belive tghat our system can sufficiently apply to the clinacal usage, however, it has also several disadvantages, such as an explosion sound and the use of water-tub. As the noise level in the explosion has been proved to be almost same compared to the Dornier System(HM-1), so the noise seems to be not a great probelm. From a point of efficienty of shock wave propagation, it is preferable that no interpolated material betwee a shock wave reflecter and a human body. Nonetheless, the adoption of a water-tub make the whole system complex. in this regard, we are trying a tgub-less sytem in mESWL, and study on another energy source, such as piezoceramics. in order to evaluate our system, not only from the efficicency in the clinical treatment and the easiness in the manipulation, but also form the economical point of view, we need more detailed information about other lithotripters. However, the development of a original made-in-japan lithotripter stimulates the researach on shock waves, and makes another step to apply the method widely to biomedical fields in this country.
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Research Products
(13 results)
