1989 Fiscal Year Final Research Report Summary
Comparative pathological and geographycal-epidemiological studies of cancer and refractory viral diseases in Nagasaki and Singapore.
| Project/Area Number |
62045029
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| Research Category |
Grant-in-Aid for Overseas Scientific Survey.
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| Allocation Type | Single-year Grants |
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| Section | University-to-University Cooperative Research |
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| Research Institution | Nagasaki University |
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Principal Investigator |
TSUCHIYAMA Hideo Nagasaki University, 学長 (80039487)
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| Co-Investigator(Kenkyū-buntansha) |
ヒン・P リー 国立シンガポール大学, 公衆衛生学, 教授
エドワード P.C.トク 国立シンガポール大学, 病理学, 教授
SHIKU Hiroshi Nagasaki University School of Medicine, 腫瘍医学, 教授 (80154194)
TAKEMOTO Tai-ichiro Nagasaki University School of Medicine, 公衆衛生学, 教授 (60010005)
MIYAMOTO Tsutomu Nagasaki University School of Medicine, 細菌学, 教授 (10004582)
LEE Hing P. National University of Singapore
TOOCK Edward P.C. National University of Singapore
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| Project Period (FY) |
1987 – 1989
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| Keywords | Nagasaki / Singapore / Hepatitis B virus / HTLV-1 / HIV / Cancer |
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| Research Abstract |
Nagasaki University and National University of Singapore collaborated for pathological and epidemiological analysis on cancer and refractory viral diseases in Nagasaki and Singapore. As viral diseases, hepatits B virus (HBV), human T lymphotropic virus type 1 (HTLV-1), human immunodeficiency virus (HIV), and their related diseases were investigated. Epidemiological analysis on HBV infection particularly on incidence of viral carriers, and pathological analysis of hepatitis, liver cirrhosis, and liver cancer were conducted in both areas. Nagasaki is relatively endemic HTLV-1 infection whereas HTLV-1 infection is very rare in Singapore. Epidemiological and geographycal difference in both areas were discussed. In Nagasaki, detailed analysis on HTLV-1 carriers and virus related diseases such as adult T cell leukemia and HTLV-1 associated myelopathy was performed. HIV was also found relatively rare in both areas. Effective diagnosis and prevention of viral infection, however, is still an important subject for both areas and the technical basis for early detection of HIV carriers was discussed. Various types of malignancy are subjects of great interest for both areas. Biological, pathological and clinical analyses were performed in stomach cancer, gynecological cancer, malignant lymphoma and leukemia.
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