1989 Fiscal Year Final Research Report Summary
Changes of brain monoamine content during learning behavior
| Project/Area Number |
62570076
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
環境生理学(含体力医学･栄養生理学)
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| Research Institution | Fujita-Gakuen Health University |
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Principal Investigator |
NOMURA Masahiko Fujita Health University, School of Medicine, Associate Professor, 医学部・生理学, 助教授 (30051527)
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| Co-Investigator(Kenkyū-buntansha) |
NAGATA Yutaka Fujita Health University, School of Medicine, Professor, 医学部・生理学, 教授 (70084499)
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| Project Period (FY) |
1987 – 1989
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| Keywords | In vivo voltammetry / Dopamine / Adrenalin / Homovanillic acid / Serotonin / 5-Hydroxyindole acetic acid / DOPAC |
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| Research Abstract |
The changes of monoamine content during the behavioral performance were measured by in vivo voltammetry method. The changes of some monoamine content in free moving animal condition showed almost the same value of those of high performance liquid chromatography analysis, which was the assay after decapitation and from the brain tissue.
As a model animals with abnormal monoamine contents, spontaneously hypertensive rats ( SHR ) were used. The lower contents of monoamine in SHR in some regional parts also detected by in vivo voltammetry method, compared with those of Wistar Kyoto rats as a control.
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[Publications] YAMAMOTO, N., HASHIMOTO, A., OKUYAMA, H., NOMURA, M.: "Effect of a-linolenate/linoleate balance on lipid compositions and learning ability of rats." Journal of Lipid Research, 29, 1013-1021, 1988.
Description
「研究成果報告書概要(欧文)」より
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