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1989 Fiscal Year Final Research Report Summary

Studies on PGI2 regulatory factor, EDCF and EDRF

Research Project

Project/Area Number 63440036
Research Category

Grant-in-Aid for General Scientific Research (A)

Allocation TypeSingle-year Grants
Research Field Circulatory organs internal medicine
Research InstitutionKYOTO UNIVERSITY

Principal Investigator

KAWAI Chuichi  3rd Div, dept of Int, 医学部, 教授 (70025659)

Co-Investigator(Kenkyū-buntansha) YUI Yoshiki  same above, 医学部, 助手 (20158330)
Project Period (FY) 1988 – 1989
KeywordsEDR / EDRF / Thrombosis / AMI / NO
Research Abstract

1. Serum prostacyclin stabilizing factor was found to be identical to apolipoprotein AI, an apolipoprotein of HDL. This factor seems to have important relation to the coronary thrombus formation.
2. A new relaxing factor from bovine retractor penis muscle was found to be RSNO and NO.
3. Serum lipoprotein was found to inhibit EDR.

  • Research Products

    (10 results)

All Other

All Publications (10 results)

  • [Publications] Ryliichi Hattorietal: "Reocclusion of the infarated vessel during acute interventions in MI" Jpn.Cie.J.52. 709-714 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Yoshiki Yui et al: "Serum prostacyclin stabilizing factor is edentical to Apo A-I" J.Clin.Invest.82. 803-807 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Yoshiki Yui et al: "mechanism for the generation of octiue sncaoth muscle in hibitory factor from bovine retroctor penis musle" B.B.R.C.164. 544-549 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Mamoru Takahashi et al: "Lipoproteins are inhibitons of EDR" Amer.J.Physial.258. 1-8 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Takeshi Aoyama et al: "Prostacyclin haef-life regulated luy HDL is decriased in AMI and UAP" Cinculation(in press).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ryuichi Hattori et al.: "Reocclusion of the infarcted vessel during acute interventions in MI." Jpn. C. J. 52. 709-714 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yoshiuki Yui et al.: "serum prostacyclin stabilizing factor is identical to Apo AI." J. Clin. Invest. 82, 803-807, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yoshiki Yui et al.: "Mechanism for the generation of active smooth muscle inhibitory factor from bovine retractor penis muscle" B.B.R.C. 164, 544-549, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mamoru Takahashi et al.: "Lipoproteins are inhibitors of EDR." Amer. J. Physiol. 258, 1-8, 1990.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Takeshi Aoyama et al.: "Prostacyclin half-life regulated by HDL is decreased in AMI and UAP" Circulation.

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1993-03-26  

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