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1990 Fiscal Year Final Research Report Summary

Proton NMR Studies on Saliva

Research Project

Project/Area Number 63570874
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Functional basic dentistry
Research InstitutionThe University of Tokushima

Principal Investigator

FUKUYTOMI Shigeru  Tokushima University, University Dental Hospital, Research Associate., 歯学部, 助手 (60199247)

Co-Investigator(Kenkyū-buntansha) MAEDA Naoki  Tokushima University, University Dental Hospital, Pesearch Associate., 歯学部附属病院, 助手 (10219272)
UEMURA Shusaburo  Tokushima University, University Dental Hospital, Professor., 歯学部, 教授 (20028799)
Project Period (FY) 1988 – 1990
KeywordsProton NMR / Human parotid saliva / Human submandibular saliva
Research Abstract

Proton NMR spectra of healthy human parotid saliva present similar spectral features regardless of age, sex, and collection time although total intensities show significant circadian rhythms. On the other hand, saliva of patients presented notably different spectral patterns which might result from specific disease. This suggests that NMR of saliva could detect change of secretory mechanism on the gland metabolism or physiological change. The major advantages of this technique would be that measurements can be performed without any pretreatments, and that it requires relatively short measurement times (less than 30 min.) and small amount of samples (0.4ml). Thus these preliminary studies suggest that high resolution proton NMR of aseptically collected saliva should be practially useful for diagnostic purposes.

  • Research Products

    (6 results)

All Other

All Publications (6 results)

  • [Publications] 野坂 篤子: "高分解能NMR法による唾液の分析(診断法開発の模索)" 歯科放射線. 28. 233- (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 野坂 篤子: "高分解能NMR法による唾液の分析II(診断法開発の模索)" 歯科放射線. 29. 213- (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Atsuko.Y.Nosaka: "Preliminary NMR studies on human saliva" Archives of Oral Biology.

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] ATSUKO NOSAKA: "Proton NMR Studies on Saliva" Dental Radiology. 28-Special Number. 91 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] ATSUKO NOSAKA: "Proton NMR Studies on Saliva 2" Dental Radiology. 29-Special Number. 107 (1889)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] ATSUKO NOSAKA: "Preliminary NMR studies on saliva" Archives of Oral Biology.

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1993-08-12  

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