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1989 Fiscal Year Final Research Report Summary

The mechanism of the expression of ganglioside induced by retinoic acid during early chick embryo

Research Project

Project/Area Number 63580139
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field 物質生物化学
Research InstitutionNational Center of Neurology and Psychiatry (NCNP)

Principal Investigator

MOMOI Takashi  NCNP, Chief researcher, 神経研究所5部, 室長 (40143507)

Project Period (FY) 1988 – 1989
KeywordsRetinoic acid / Cellular retinoic acid / binding protein / Retinoic acid receptor / neurogenesis / neural tube
Research Abstract

We previously demonstrated the presence of cellular retinoic acid binding protein II, chick-CRABP II, in chick embryos. In the present study, we investigated the distribution of chick-CRABP II in 14-day chick embryos by means of immunoblot analysis. Chick-CRABP II was expressed in skin, muscle, bone with tendon of the embryos, but not expressed in the nervous system. In adult chick tissues, chick CRABP II was not detected on immunoblotting; Chick-CRABP II in adults amounts to less than long/mg soluble embryonic protein involved in the development of specific tissues, such as bone, muscle and skin.

  • Research Products

    (14 results)

All Other

All Publications (14 results)

  • [Publications] Momoi,T.Kumagai,H.Momoi,M.: "Retinoic acid receptor in the chick limb buds in the early developmental stages." Biochem.Biophys.Res.Commun.(1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Momoi,M.,Yamagata,T.Ichihashi,K.,Yanagisawa,M.,Yamakado,M.: "Expression of cellular retinoic acid binding protein in the developing nervous system of mouse embryo." Dev.Brain Res.(1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Momoi,T.,Momoi,M.,Kumagai,H.,Utsumi,H.Tomita,M.S.Takao,A.: "The expression of retinoic acid receptor in the chick limb bud during early developmental stages." Proc.Jap,Acad.65. 191-194 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kitamoto,T.,Momoi,M.and Momoi,T.: "Expression of a novel cellular retinoic acid binding protein(CRABP II)in the chick embryo." Biochem.Biophys.Res.Commun.164. 531-536 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Aikawa,H.,Momoi,T.Kitamoto,T.Arahata,K.and Momoi,M.: "Expression of cellular retinoic acid binding protein(CRABP)in adult rat brain." Biomedical Res.10. 247-250 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Momoi,M.,Hayasaka,M.Hanaoka,K.and Momoi,T.: "The expression of cellular retinoic acid binding protein(CRABP)in the neural tube and notochord of mouse embryo." Proc.Jap.Acad.65. 9-11 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 桃井隆: "脳の神経栄養因子と先天代謝異常" 平凡社, 14 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 桃井真里子、桃井隆: "形態形成因子としてのレチノイン酸と神経形成" 医学書院, 11 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Momoi, T., Kumagai, H. and Momoi, M.: "Retinoic acid receptor in the chick limb buds in the early developmental stages." Biochem. Biophys. Res. Commun. (1990).

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Momoi, M., Yamagata, T., Ichihashi, K., Yanagisawa, M., Yamakado, M. and Momoi, T.: "Expression of cellular retinoic acid binding protein in the developing nervous system of mouse embyo." Dev. Brain Res. (1990).

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Momoi, T., Momoi, M., Kumagai, H., Utsumi, H. Tomita, M.S., and Takao, A.: "The expression of retinoic acid receptor in the chick limb bud during early developmental stages." Proc. Jap. Acad. 65, 191-194 (1989).

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kitamoto, T., Momoi, M. and Momoi, T.: "Expression of a novel cellular retinoic acid binding protein (CRABP II) in the chick embryo." Biochem. Biophys. Res. Commun. 164, 531-536 (1989).

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Aikawa, H., Momoi, T., Kitamoto, T., Arahata, K. and Momoi, M.: "Expression of cellular retinoic acid binding protein (CRABP) in adult rat brain." Biomedical Res. 10, 247-250, (1989).

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Momoi, M., Hayasaka, M., Hanaoka, K. and Momoi, T.: "The expression of cellular retinoic acid binding protein (CRABP) in the neural tube and notochord of mouse embryo." Proc. Jap. Acad. 65, 9-11, (1989).

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1993-03-26  

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