mRNAの再スプライシング現象から探る未知のmRNA品質管理機構

Products Report

• Project Area: Diversity and asymmetry achieved by RNA program
• Project/Area Number: 23112722
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: Fujita Health University
• Principal Investigator: 前田 明 藤田保健衛生大学, 総合医科学研究所, 教授 (50212204)
• Project Period (FY): 2011-04-01 – 2013-03-31

Research Products

• [Journal Article] Nested introns in an intron : Evidence of multi-step splicing in a large intron of the human dystrophin pre-mRNA. (2013)
  • Author(s): Suzuki, H., Kameyama, T., Ohe, K. Tsukahara, T., Mayeda, A.
  • Journal Title: FEBS Letters Volume: 587 Pages: 555-561
  • DOI: 10.1016/j.febslet.2013.01.057.
  • Peer Reviewed
• [Journal Article] Re-splicing of mature mRNA in cancer cells promotes activation of distant weak alternative splice sites. (2012)
  • Author(s): Kameyama, T., Suzuki, H., Mayeda, A.
  • Journal Title: Nucleic Acids Res. Volume: 40 Pages: 7896-7906
  • DOI: doi: 10.1093/nar/gks520.
  • Peer Reviewed
• [Presentation] がん細胞で発見された成熟mRNA再スプライシングから正常細胞で重要なmRNA品質管理機構が想定できる。 (2012)
  • Author(s): 亀山 俊樹、前田 明
  • Organizer: 第35回 分子生物学会年会 : ワークショップ「RNA病解明への挑戦」
  • Place of Presentation: 福岡、日本
  • Year and Date: 2012-12-11 – 2012-12-14
• [Presentation] Mature mRNA resplicing in cancer cells postulates undiscovered quality control mechanism of mRNA in normal cells. (2012)
  • Author(s): Kameyama, T., Mayeda, A.
  • Organizer: Gordon Research Conference : The Biology of Post-Transcriptional Gene Regulation
  • Place of Presentation: Newport, U.S.A.
  • Year and Date: 2012-07-15 – 2012-07-20
• [Presentation] Mature mRNA resplicing in cancer cells postulates undiscovered quality control mechanism of mRNA in normal cells. (2012)
  • Author(s): Kameyama, T., Mayeda, A.
  • Organizer: The 22^<nd> CDB Meeting : RNA Sciences in Cell and Developmental Biology ll
  • Place of Presentation: Kobe, Japan
  • Year and Date: 2012-06-11 – 2012-06-13
• [Presentation] Resplicing of mature mRNA in cancer cells : Two-step splicing Mechanism to activate far distant alternative splice sites. (2011)
  • Author(s): Kameyama, T., Mayeda, A.
  • Organizer: Eukaryotic RNA Processing Meeting
  • Place of Presentation: Cold Spring Harbor, U.S.A.
  • Year and Date: 2011-08-23 – 2011-08-27
• [Presentation] Aberrant re-splicing of mature spliced mRNA discovered in cancer cells : Considering its generality and significance. (2011)
  • Author(s): Kameyama, T., Mayeda, A.
  • Organizer: The 16^<th> annual meeting of the RNA society
  • Place of Presentation: Kyoto, Japan
  • Year and Date: 2011-07-14 – 2011-07-18
• [Book] Chapter 30 : ln vitro splicing assays (Alternative pre-mRNA splicing : Theory and protocols) (2012)
  • Author(s): Mayeda, A., Krainer, A.R. (Stamm, S., Luhrmann, R., eds.)
  • Total Pages: 10(622)
  • Publisher: Wiley-VCH Verlag, Weinheim, Germany