レゾナンスバイオ国際活動支援

• Project Area: Resonance Biology for Innovative Bioimaging
• Project/Area Number: 15K21746
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Multi-year Fund
• Review Section: Biological Sciences
• Research Institution: Institute of Physical and Chemical Research
• Principal Investigator: 宮脇 敦史 国立研究開発法人理化学研究所, 脳神経科学研究センター, チームリーダー (80251445)
• Co-Investigator(Kenkyū-buntansha): 今村 健志 愛媛大学, 医学系研究科, 教授 (70264421) ; 松田 道行 京都大学, 生命科学研究科, 教授 (10199812)
• Project Period (FY): 2015-11-06 – 2021-03-31
• Project Status: Granted (Fiscal Year 2019)
• Budget Amount: ¥63,700,000 (Direct Cost: ¥49,000,000、Indirect Cost: ¥14,700,000); Fiscal Year 2019: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000); Fiscal Year 2018: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000); Fiscal Year 2017: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000); Fiscal Year 2016: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000); Fiscal Year 2015: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
• Keywords: バイオイメージング / FRET / 顕微鏡技術 / ケミカルバイオロジー / 画像処理 / ワークショップ / シンポジウム / 画像解析

Outline of Annual Research Achievements

5月に、科研費新学術領域「レゾナンスバイオ」（代表：理研 宮脇敦史）、新学術領域「植物新種誕生の原理」（代表：名古屋大学 東山哲也）、EMBO Practical Course “Functional live imaging of plants” （代表：名古屋大学：東山哲、Universitaet Heidelberg：Alexis Maizel、Heinrich-Heine-Universitaet Duesseldorf：Ruediger Simon）が主催し、3グループの若手研究者が一堂に集まり、科学議論を行った。主な目的は、１）若手研究者たちの国際感覚の育成、２）現行プロジェクトおよび将来の研究に資する関係構築である。また、ミーティング前日に基礎生物学研究所、生理学研究所、分子科学研究所の研究室見学を行い、自然科学研究機構3研究所の研究者たちと意見交換の機会を持った。
科研費新学術領域「レゾナンスバイオ」は最終年度を迎え、集大成として、10月にResonance Bio International Symposiumを開催した。5年間の領域の成果報告を行うとともに、バイオイメージング分野の最先端で活躍する9名の研究者を海外から招聘し、講演会を開催した。また、産学の交流の場とするため、学術だけでなく産業界にも本シンポジウムを周知した。会期3日間で、参加者は333名であった。

Current Status of Research Progress

1: Research has progressed more than it was originally planned.

Reason

＜若手育成＞本年度に開催した国際若手の会は、他領域（新学術領域「植物新種誕生の原理」（代表：名古屋大学 東山哲也））とドイツの研究機関EMBOと共催することができた。過去2年間はアジアを中心とした若手研究者との交流が主であったが、今回はヨーロッパ各国から集まった若手研究者が参加し、より多様性のある会にすることができた。
＜シンポジウム＞Resonance Bio International Symposiumを開催し、Jin Zhang（UC San Diego)、Ilia V. Yampolsky（Russian Academy of Sciences）、Hisataka Kobayashi（NIH)、Joachim Goedhard（University of Amsterdam）、Scott E. Fraser(University of Southern California)、Paul Kubes(University of Calgary)、Won Do Heo（KAIST）、Robert E. Campbell（University of Alberta）Jared E. Toettcher(Princeton University)9名を招聘した。講演だけでなく、ポスター賞選定委員としても携わってもらった。3日間の会期中、班員との活発な意見交換が行われ今後の研究連携への発展が期待される。

Strategy for Future Research Activity

本領域に関係する国際会議などで先端研究の情報収集をする。また本領域の成果を学会などで広く周知し、今後の研究連携の推進を図っていく。領域の成果周知のため、ウェブサイトへの成果更新も引き続き行う。社会情勢を鑑みながら、可能であれば、勢いのある研究者を招聘し、講演会やフォーラムを開催する予定である。

Research Products

• [Int'l Joint Research] The Scripps Research Institute(米国)
• [Int'l Joint Research] The Chinese University of Hong Kong/National Tsing Hua University(その他の国・地域)
• [Int'l Joint Research] EMBO(ドイツ)
• [Int'l Joint Research] 中央研究院(その他の国・地域)
• [Int'l Joint Research] Salk Institute(アメリカ)
• [Int'l Joint Research] Academia Sinica(台湾)
• [Int'l Joint Research] Stanford大学(アメリカ)
• [Presentation] Whole-organ imaging for cochlear duct morphogenesis -Differential growth hypothesis for bending force generation (2019)
  • Author(s): Mamoru Ishii
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Establishment of live imaging system for the analysis of bone growth effect of C-type natriuretic peptide using FRET biosensor mice (2019)
  • Author(s): Keisho Hirota
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] SLIPT and photoSLIPT: chemical and optochemical tools for controlling protein localization in living cells (2019)
  • Author(s): Shinya Tsukiji
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Chemogenetic control of protein activity in living cells using synthetic protein-assembled clusters (2019)
  • Author(s): Masaru Yoshikawa
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Cancer cell-derived prostanoids shape the pro-tumor microenvironment, enhancing calcium signaling in cancer cells (2019)
  • Author(s): Yoshinobu Konishi
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics (2019)
  • Author(s): Tomoaki Kinjo
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Enhanced fluorescence of near-infrared fluorescent proteins by the deficiency of biliverdin reductase-A gene in vivo (2019)
  • Author(s): Kenju Kobachi
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Imaging neuronal network controlling circadian and ultradian calcium rhythms in mammals (2019)
  • Author(s): Ryosuke Enoki
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] In vivo two-photon deep and wide-field imaging utilizing novel fluoropolymer PEO-CYTOP nanosheet (2019)
  • Author(s): Taiga Takahashi
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Two-photon excitation spinning-disk confocal microscopy for higher-dimensional bioimaging (2019)
  • Author(s): Kohei Otomo
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Super-resolution Imaging by Vector Beams (2019)
  • Author(s): Shun-ichi Sato
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] In vivo visualization of dendritic spines in deep regions of the mouse prefrontal cortex with two-photon excitation adaptive optical microscopy (2019)
  • Author(s): Kazushi Yamaguchi
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Two-photon pulsed STED nanoscopy utilizing electrically controllable components (2019)
  • Author(s): Hirokazu Ishii
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Near-Infrared Light Triggered Cancer Theranostics Based on Rear-Earth Doped Ceramics Nanoparticles (2019)
  • Author(s): Masao Kamimura
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research / Invited
• [Presentation] Detection of protein-conformation switch by second harmonic generation microscopy (2019)
  • Author(s): Taro Ichimura
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Quantitative Visualization of Lipid Distribution in Mice Liver by Using Near-Infrared Hyperspectral Imaging (2019)
  • Author(s): Yuichi Kitagawa
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Near-Infrared Fluorescence Lifetime-Based Contactless Temperature Imaging for Deep Biological Tissues by Using Rare-Earth-Doped Ceramics Particles (2019)
  • Author(s): Keiji Miyata
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Synthesis of Bright NIR-II Fluorescent Polymer Nanoparticle with IR-1061 Dye via Mild Heating-Cooling Process for Deep Bioimaging in the Second Biological Window (2019)
  • Author(s): Hisanori Kobayashi
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Over-1000nm Near-Infrared Fluorescence Properties of IR-1061 Dye-Loaded Micelles Dispersed in Different Concentration of Hydrogen Ion (2019)
  • Author(s): Kazuno Ikeda
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Conjugation of Gd-DOTA to IR1061-PEG based micelles for dual MRI/OTN-NIR imaging (2019)
  • Author(s): Doan Thi Kim Dung
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Optical and magnetic multimodal bioimaging probes based on rare-earth doped ceramic nanophosphors (2019)
  • Author(s): Karina Nigoghossian
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Phosphate-Based Rapid Optical Clearing for Three-Dimensional Fluorescence Imaging of Mouse Brains (2019)
  • Author(s): Masakazu Umezawa
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Computed Tomography for In Vivo Deep Over-Thousand-Nanometer Near-Infrared (OTN-NIR) Fluorescence Imaging (2019)
  • Author(s): Masakazu Umezawa
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Stabilization of Indocyanine Green by Energy Transfer in Block Copolymer Micelles (2019)
  • Author(s): Gil Yeroslavsky
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Development of new photoactivatable fluorophores for in vivo/ex vivo cell labeling (2019)
  • Author(s): Hiroki Kashima
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Rational design of fluorescence probes based on quantum chemical prediction of intramolecular spirocyclization (2019)
  • Author(s): Sascha Keller
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Development of Fluorescent Probes for Glycosidase Activities and Application to Cancer and Benign Specific Fluorescence Imaging (2019)
  • Author(s): Kyohhei Fujita
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Trimmed Median PCA (2019)
  • Author(s): Shin Yoshizawa
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Electric-field control of fluorescence protein emissions at the metal-solution interface (2019)
  • Author(s): Hidekazu Tsutsui
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Cloud-based image processing system: RBICP (2019)
  • Author(s): Masahiko Morita
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Structural analysis of nucleic acids by controlling the fluorescence blinking (2019)
  • Author(s): Kiyohiko Kawai
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Deep learning for cell segmentation with less annotation (2019)
  • Author(s): Kazuya Nishimura
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research / Invited
• [Presentation] Cell Tracking by estimating cell motions for high-throughput screening (2019)
  • Author(s): Junya Hayashida
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Genetically encoded reporter for bimodal optical and PET imaging in the mammalian brain (2019)
  • Author(s): Masafumi Shimojo
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research / Invited
• [Presentation] Nanoscale dynamics and localization of single endogenous mRNAs in stress granules (2019)
  • Author(s): Takashi Funatsu
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Visual Interpretation of U-Net in Bio-medical Images Classification (2019)
  • Author(s): Novanto Yudistira
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Feedback Attention Mechanism For Convolutional Neural Network (2019)
  • Author(s): Yuki Hiramatsu
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Automatic Image Preprocessing Method Using Deep Learning (2019)
  • Author(s): Sota Kato
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Visualization of Pixel-wise Difficulty of Segmentation by CNN (2019)
  • Author(s): Daisuke Matsuzuki
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Cytoskeleton-anchoring probes for nanoimaging of oxidative stress (2019)
  • Author(s): Tasuku Hirayama
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Optogenetic control of cell-cell communication in the Notch signaling pathway (2019)
  • Author(s): Akihiro Isomura
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Multi-photon patterned illumination using a digital micromirror device (2019)
  • Author(s): Keisuke Isobe
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Nanosheet Wrapping Technology ~Coverslip-free imaging for looking deeper into a tissue at high resolution~ (2019)
  • Author(s): Yosuke Okamura
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Porous nanosheet wrapping: a novel immobilization method for long-term imaging of zebrafish development without anesthesia (2019)
  • Author(s): Hong Zhang
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Nanostructure and molecular dynamics of dendritic spines (2019)
  • Author(s): Shigeo Okabe
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Highly sensitive, multiplex bioluminescence imaging of cancer metastasis in deep tissues (2019)
  • Author(s): Takahiro Kuchimaru
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Development of multi-cell-type segmentation algorithm by unsupervised feature learning (2019)
  • Author(s): Yuya Kobayashi
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Development of the pH-responsive photoacoustic imaging agent (2019)
  • Author(s): Koki Tsuchiya
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Beyond multicolor superresolution microscopy: Accurate 3D registration and distance measurement (2019)
  • Author(s): Atsushi Matsuda
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Optical Control of Cell Signaling by Genetically Encoded PhyB-PIF System (2019)
  • Author(s): Kazuhiro Aokii
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Quantification of GPCR Signaling by Multiplexed Fluorescence Imaging (2019)
  • Author(s): Ryosuke Tany
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Development and application of a new optogenetic system to manipulate intracellular contractile force (2019)
  • Author(s): Kei Yamamoto
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Allele-Selective Genome Editing by Fine-Tuning CRISPR-Cas9 Activity (2019)
  • Author(s): Masaki Kawamata
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Optical induction of signaling and plasticity of single dendritic spines by photoactivatable CaMKII (2019)
  • Author(s): Akihiro Shibata
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Analysis of acetylcholine-induced tissue-widely synchronized Ca2+ oscillations in rat submandibular gland using intravital imaging (2019)
  • Author(s): Akihiro Nezu
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Multimodal multiphoton imaging of plasma membrane by dye-based second-harmonic and sum-frequency generation (2019)
  • Author(s): Takaha Mizuguchi
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Multi-scale imaging from the whole brain level to the ultrastructure level by using a modified ScaleS method (2019)
  • Author(s): Hiroyuki Hioki
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Real time recording of clock gene expression in multiple tissues of freely moving mice (2019)
  • Author(s): Toshiyuki Hamada
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Bio-image informatics for whole brain imaging and analysis of neural activity of C. elegans (2019)
  • Author(s): Yu Toyoshima
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Development of Chemical Tools with Fluorescence Switch for Biomolecular Imaging (2019)
  • Author(s): Yuichiro Hori
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Single particle motions of axonal proteins captured by a confocal laser scanning microscopy (2019)
  • Author(s): Kazunari Mouri
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] A cell cycle-dependent CRISPR-Cas9 activation system for increased accuracy of genome editing (2019)
  • Author(s): Wataru Nomura
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Development of a pH-adjustable tissue clearing solution for biological multicolor deep imaging (2019)
  • Author(s): Kazuya Okami
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Multi-modal optical coherence microscopy at longer wave-length range using wavelength tunable ultrashort pulse fi-ber laser for deep imaging (2019)
  • Author(s): Norihiko Nishizawa
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] An End-to-end CNN and CLSTM Network with 3D Anchors for Mitotic Cell Detection in 4D Microscopic Images (2019)
  • Author(s): Jianqing Liu
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Development of activatable fluorescence probes for detecting basic carboxypeptidase activity (2019)
  • Author(s): Hirohisa Iwaki
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] mage Denoiser for Microscopic Images Based on Noising and Denoising Approach (2019)
  • Author(s): Akinori Hidaka
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] A new optical method for identifying a time window of syn-aptic plasticity in hippocampus (2019)
  • Author(s): Akihiro Goto
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Data mining of microspectroscopic image using intrinsic features of overcomplete independent bases (2019)
  • Author(s): Yu Nagashima
  • Organizer: Resonance Bio International Symposium
  • Int'l Joint Research
• [Presentation] Foerster resonance energy transfer-assisted photoactivation of CRY2 for the optical control of protein interactions by two-photon excitation microscopy (2019)
  • Author(s): Tomoaki Kinjo
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] In vivo two-photon laser ablation of single neural processes within deep regions ofliving mouse brains (2019)
  • Author(s): Kazuhisa Yamaguchi
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] Visualization of rapid elimination of hematogenous metastatic tumor cells by NK cells in the lung (2019)
  • Author(s): Hiroshi Ichise
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] Quantification of GPCR signaling by live cell imaging (2019)
  • Author(s): Ryosuke Tany
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] Two-photon excitation spinning disk microscopy for multi-dimensional bioimaging (2019)
  • Author(s): Kohei Otomo
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] Development of nucleus-specific fluorescent dyes and nucleus imaging of mammalian and plant cells (2019)
  • Author(s): Akinobu Nakamura
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] Three-Dimensional Imaging of Over-1000-Nanometer (OTN) Near-Infrared Fluorescence by Sheet-Laser Excitation (2019)
  • Author(s): Masakazu Umezawa
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] Differential contributions of nonmuscle myosin IIA and IIB to cytokinesis in human immortalized fibroblasts (2019)
  • Author(s): Kei Yamamoto
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] Multimodal imaging systems based on rare-earth doped ceramic nanophosphors (2019)
  • Author(s): Karina Nigoghossian
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] Morphological analysis of dendritic spine structures in the hippocampal neurons activated during fear memory recall by whole-cell high-resolution imaging using Airyscan FAST microscopy (2019)
  • Author(s): Keiichiro Minatohara
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] Visualization of directional-transport mechanisms in living fertilized eggs (2019)
  • Author(s): Hirokazu Ishii
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] In vivo imaging in mouse brains in wide and deep regions utilizing novel nanosheets “PEO-CYTOP” (2019)
  • Author(s): Taiga Takahashi
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] FRET Imaging Analysis of RB phosphorylation and Cell Cycle Progression (2019)
  • Author(s): Masaya MUKAI
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] Photoprotection of Indocyanine Green by Energy Transfer in Various Micellar Systems (2019)
  • Author(s): Gil Yeroslavsky
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] Visualizing Neuronal Circuits Controlling Circadian and Ultradian Rhythms in Mammals (2019)
  • Author(s): Ryosuke Enoki
  • Organizer: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • Int'l Joint Research
• [Presentation] Illuminating Neuronal Circuits Controlling Circadian and Ultradian Rhythms in Mammals (2018)
  • Author(s): Ryosuke Enoki
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Fabrication of Fluoropolymer Nanosheets as a Wrapping Mount for High Quality Tissue Imaging (2018)
  • Author(s): Yosuke Okamura
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Development of multi-point scanning two-photon microscopy utilizing polarizing optics and its application for intravital imaging (2018)
  • Author(s): Ai Goto
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Manipulation of fission yeast cell cycle by red/infrared Lightinduced Dimerization of PhyB-PIF (2018)
  • Author(s): Yuhei Goto
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Cytoskeletal dynamics for directional transport in the fertilized ascidian eggs (2018)
  • Author(s): Hirokazu Ishii
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Polymer Conjugated Nanophosphors for Over-1000 nm Near- Infrared Fluorescence Imaging (2018)
  • Author(s): Masao Kamimura
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] A multi-bioluminescence reporter system visualizes tumorstromal interactions during therapeutic treatment of bone metastasis (2018)
  • Author(s): Takahiro Kuchimaru
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Two-photon excitation spinning disk confocal microscopy utilizing two laser light sources (2018)
  • Author(s): Takafumi Kamada
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Structured illumination microscopy-based computational analysis of spine head geometry and its application to live cell imaging (2018)
  • Author(s): Yutaro Kashiwagi
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Highly-sensitive in vivo tracking of cancer cells using nearinfrared bioluminescence technologies (2018)
  • Author(s): Misa Minegishi
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Application of a highly photostable near-infrared labeling agent in muse brain imaging in vivo (2018)
  • Author(s): Ryosuke Kawakami
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Development of fluorescent probes with m6A-binding protein for detection of RNA methylation (2018)
  • Author(s): Keisuke Nomura
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Development of spontaneously blinking fluorophores based on nucleophilic addition of intracellular glutathione for superresolution imaging (2018)
  • Author(s): Akihico Morozumi
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Sub-100 nm scale nanoarray for single-exosome analysis (2018)
  • Author(s): Kyohei Okubo
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
• [Presentation] Theranostic nanosystems based on luminescence of rare-earth doped ceramic nanophosphors (2018)
  • Author(s): Karina Nigoghossian
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Spectral-morphological classification of liver fibrosis using multi-photon excitation microscopy and marker-based segmentation (2018)
  • Author(s): Takashi Saitou
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Improvements of two-photon excitation microscopy for clear visualization of intravital subcellular structures (2018)
  • Author(s): Kohei Otomo
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] In vivo manipulation of signal transduction using red/infrared light in C. elegans (2018)
  • Author(s): Shigekazu Oda
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Single-cell kinase activity measurements from the mouse retina by two-photon ex vivo live imaging. (2018)
  • Author(s): Shinya Sato
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Non-empirical Design of Spontaneously Blinking Fluorophores for Super-resolution Imaging (2018)
  • Author(s): Ryo Tachibana
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Genetically encoded reporter for bimodal optical and PET imaging in the mammalian brain. (2018)
  • Author(s): Masafumi Shimojo
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Development of 2 photon wide-field light sheet microscopy for Medaka (2018)
  • Author(s): Sota Takanezawa
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Temporal Profile of Notch Signaling Activation during Vertebrate Somitogenesis (2018)
  • Author(s): Akari Takagi
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Real-Time Imaging of Bile Excretion of Nanoparticle Using In Vivo Deep Imaging System with Near-Infrared Fluorescent Probes (2018)
  • Author(s): Masakazu Umezawa
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Application of novel CYTOP nanosheet for in vivo imaging of living mouse brain (2018)
  • Author(s): Taiga Takahashi
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Using nanosheet instead of coverslip for facilitating deep tissue imaging (2018)
  • Author(s): Hong Zhang
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] 3D Beef Marbling Extraction (2018)
  • Author(s): Shin Yoshizawa
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] In vivo two-photon laser ablation within deep regions of living mouse brains (2018)
  • Author(s): Kazushi Yamaguchi
  • Organizer: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • Int'l Joint Research
• [Presentation] Visualization of transcriptional activities in living fish (2017)
  • Author(s): Kenta Terai
  • Organizer: The 1st ABiS Symposium Towards the Future of Advanced Bioimaging for Life Sciences
  • Place of Presentation: 自然科学研究機構 岡崎コンファレンスセンター（愛知県岡崎市）
  • Year and Date: 2017-02-19
  • Int'l Joint Research
• [Presentation] Development of a new murine model of bone metastasis using bioluminescence imaging (2017)
  • Author(s): Takahiro Kuchimaru, Shinae Kizaka-Kondoh
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Bio-image Informatics for Whole-brain Activity Imaging (2017)
  • Author(s): Yu Toyoshima
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Detection of LacZ-Positive Cells in Living Tissue with Single-Cell Resolution (2017)
  • Author(s): Mako Kamiya, Yasuteru Urano
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Development of spontaneously blinking fluorophores based on nucleophilic addition of intracellular glutathione for super-resolution imaging (2017)
  • Author(s): Akihico Morozumi, Mako Kamiya, Shinnosuke Uno, Keitaro Umezawa, Toshitada Yoshihara, Seiji Tobita, Yasuteru Urano
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] A novel method of analyzing molecular activities at single cell level (2017)
  • Author(s): Ayako Imanishi, Masaya Sato, Kenta Sumiyama, Kazuhiro Hotta, Michiyuki Matsuda, and Kenta Terai
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Visual Mapping of Strain in Elastic Silicone Polymers Based on Energy Transfer Phenomena (2017)
  • Author(s): Gil Yeroslavsky, Masao Kamimura, Kohei Soga
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Treadmilling of microtubules drives the directional transport of maternal factors in fertilized ascidian eggs (2017)
  • Author(s): Hirokazu Ishii, Tomomi Tani
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] A Fluorescent Probe for Quick Live-Cell Protein Labeling (2017)
  • Author(s): Jingchi Gao
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Two-photon imaging within living mouse brains improved by easy modifications in the laser irradiation condition (2017)
  • Author(s): Kazushi Yamaguchi, Ryoji Kitamura, Ryosuke Kawakami, Tomomi Nemoto
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Multi-point scanning two-photon microscopy by utilizing high-peak-power lasers (2017)
  • Author(s): Kohei OTOMO, Tomomi NEMOTO
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Imaging and manipulation of temperature in single living cells (2017)
  • Author(s): Kohki Okabe
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Challenge to 3-Dimensional Imaging of Brain Vasculature by Near-Infrared Fluorescence Probe with Light-Sheet Excitation System (2017)
  • Author(s): Masakazu Umezawa, Moe Yoshida, Toshihiro Sera, Hideo Yokota
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Over-1000 nm Near-Infrared (OTN-NIR) Fluorescence in vivo Imaging (2017)
  • Author(s): Masao Kamimura
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] A multi-bioluminescence reporter system visualizes crosstalk between cancer cells and bone marrow microenvironment (2017)
  • Author(s): Misa Minegishi, Tatsuhiro Isozaki, Satoshi Fujimori, Takahiro Kuchimaru
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Development of fluorescent/luminescent protein-based biosensors for visualizing kinase activity in living cells (2017)
  • Author(s): Naoki Komatsu, Michiyuki Matsuda
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Analysis for the activity and phosphorylation states of synaptic proteins (2017)
  • Author(s): Tomohisa Hosokawa
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Object Segmentation by Integrating Multiple Deep Networks (2017)
  • Author(s): Yuki Hiramatsu and Kazuhiro Hotta
  • Organizer: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • Int'l Joint Research
• [Presentation] Detection of LacZ-Positive Cells in Living Tissue with Single-Cell Resolution (2017)
  • Author(s): Mako Kamiya
  • Organizer: The 1st ABiS Symposium Towards the Future of Advanced Bioimaging for Life Sciences
  • Place of Presentation: 自然科学研究機構 岡崎コンファレンスセンター（愛知県岡崎市）
  • Int'l Joint Research
• [Presentation] Metabolite Gradients (2016)
  • Author(s): 下薗哲,宮脇敦史
  • Organizer: Conference on Resonace Biology for Innovation Bioimaging
  • Place of Presentation: KKRホテル熱海(静岡県熱海市）
  • Year and Date: 2016-03-17
• [Presentation] Spontaneously blinking fluorophores for super-resolution imaging (2016)
  • Author(s): 神谷真子
  • Organizer: Conference on Resonace Biology for Innovation Bioimaging
  • Place of Presentation: KKRホテル熱海(静岡県熱海市）
  • Year and Date: 2016-03-17
• [Presentation] Two-photon excitation spinning disk confocal microscopy by utilizing a high-speak-power 1042-nm laser (2016)
  • Author(s): 大友康平、日比輝正、山中祐美、山中博史、根本知己
  • Organizer: Conference on Resonace Biology for Innovation Bioimaging
  • Place of Presentation: KKRホテル熱海(静岡県熱海市）
  • Year and Date: 2016-03-17
• [Presentation] レゾナンスバイオのためのクラウド型情報処理システム (2016)
  • Author(s): 森田雅彦、西村将臣、辻村有紀、井尻敬、吉澤信、横田秀夫
  • Organizer: Conference on Resonace Biology for Innovation Bioimaging
  • Place of Presentation: KKRホテル熱海(静岡県熱海市）
  • Year and Date: 2016-03-17
• [Presentation] がん転移研究のためのがんモデルメダカの開発とイメージング応用 (2016)
  • Author(s): 出口友則、成瀬清、今村健志
  • Organizer: Conference on Resonace Biology for Innovation Bioimaging
  • Place of Presentation: KKRホテル熱海(静岡県熱海市）
  • Year and Date: 2016-03-16
• [Presentation] Rare-earth Doped Cramic NAnophosphors for Over-1000nm Near-infrared Luminescence Nanothermometry (2016)
  • Author(s): Kamimura Masao, Kohei Soga
  • Organizer: Conference on Resonace Biology for Innovation Bioimaging
  • Place of Presentation: KKRホテル熱海(静岡県熱海市）
  • Year and Date: 2016-03-16
• [Presentation] CT Imaging with X-ray, Neutron, and Near Infrared Rays (2016)
  • Author(s): Yoshihiro Sera, Hideo Yokota
  • Organizer: Conference on Resonace Biology for Innovation Bioimaging
  • Place of Presentation: KKRホテル熱海(静岡県熱海市）
  • Year and Date: 2016-03-16
• [Remarks] 共鳴誘導で革新するバイオイメージング
  • URL: https://reso.m.ehime-u.ac.jp/
• [Funded Workshop] Resoance Bio International Symposium (2019)
• [Funded Workshop] Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies” (2019)
• [Funded Workshop] International Meeting on Bioimaging for Young Researchers "Chanpuru" (2018)
• [Funded Workshop] The 1st ABiS Symposium Towards the Future of Advanced Bioimaging for Life Science (2017)
  • Place of Presentation: 自然科学研究機構岡崎コンファレンスセンター（愛知県岡崎市）
  • Year and Date: 2017-02-19
• [Funded Workshop] Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers (2017)
• [Funded Workshop] Resonance Bio Workshop 2017 (2017)
  • Place of Presentation: 自然科学研究機構基礎生物学研究所（愛知県岡崎市）
• [Funded Workshop] 国際連携企画技術講習会 (2017)
  • Place of Presentation: 愛媛大学医学部（愛媛県東温市）
• [Funded Workshop] Forum (Dr.Jan Ellenberg) (2017)
  • Place of Presentation: 理化学研究所（埼玉県和光市）
• [Funded Workshop] レゾナンスバイオ公開シンポジウム「Swinging on the Chromophore」 (2016)
  • Place of Presentation: 熱海
  • Year and Date: 2016-03-16