思春期主体価値・国際活動支援班

• Project Area: Science of personalized value development through adolescence: integration of brain, real-world, and life-course approaches
• Project/Area Number: 16K21720
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Multi-year Fund
• Review Section: Complex systems
• Research Institution: The University of Tokyo
• Principal Investigator: 笠井 清登 東京大学, 医学部附属病院, 教授 (80322056)
• Project Period (FY): 2016-06-30 – 2021-03-31
• Project Status: Granted (Fiscal Year 2019)
• Budget Amount: ¥56,290,000 (Direct Cost: ¥43,300,000、Indirect Cost: ¥12,990,000); Fiscal Year 2020: ¥13,000,000 (Direct Cost: ¥10,000,000、Indirect Cost: ¥3,000,000); Fiscal Year 2019: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000); Fiscal Year 2018: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000); Fiscal Year 2017: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000); Fiscal Year 2016: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
• Keywords: 思春期 / 主体価値 / コホート研究 / リカバリー / Well-being（ウェルビーイング） / 国際共同研究 / 国際比較研究 / 若手育成 / 認知科学

Outline of Annual Research Achievements

思春期科学国際連携ネットワークを発展的に強化した。主に英米豪加の思春期学研究者との連携（下記1～5）と海外派遣後の研究（6）を継続した。
(1)　令和元年秋に、英国Trevor Robbins博士、Barbara Sahakian博士を招聘して国際シンポジウムを開催し、思春期共同研究ネットワークの拡大・強化を図った。同シンポジウムにて帰国後の海外派遣研究員3名を含む、本新学術領域に携わる研究者が研究成果を発表し、両博士の専門的見地からの助言を得た。(2)　令和元年夏に、英国のSarah Sullivan博士らALSPAC研究チームを招聘し、国際シンポジウムを実施し、今後の日英共同研究に関するアクションプランを策定した。(3)　英国ロンドン大学のMarcus Richards博士と定期的な連絡を通じて、1946British Birth Cohortや東京ティーンコホート（TTC）のデータを用いた共同研究を進めている。(4)　令和元年夏に、米国Fordham大学のJordan DeVylder博士を招聘し，セミナーを実施した上で，TTCデータを用いた共同研究を進めた。(5)　リカバリー研究は、令和元年夏に、米国カルフォルニア大学のZidonies博士の下、派遣研究を行った。研究成果の普及・実装に関する科学を学び、リカバリー分野の介入研究立案の準備を整えた。(6)　海外派遣は、平成31年度までに派遣を終えた研究員4名（豪国1、英国2、オーストリア1）が、研究を継続した。豪国派遣研究員は、TTCや豪国コホートデータを用いた共同研究を継続、英国派遣研究員1名は、上記(1)の通り指導者を招聘し連携強化を図り、もう1名は大規模脳画像データと機械学習技術を用いた個人差の神経基盤理解を、オーストリア派遣研究員は、安静時fMRIから報酬予期時の線条体活動の予測モデル構築の共同解析を行った。

Current Status of Research Progress

1: Research has progressed more than it was originally planned.

Reason

平成31年度は、英国MRCとの研究では、①1946 British Birth Cohortデータにて、思春期の主体価値と自己制御の相互作用が、高齢期のウェルビーイングを予測することを示した研究、②中年期女性の主体価値と高齢期の認知機能の関連を示した研究、③TTCデータにて、思春期の自己制御と、その後の主体価値形成につながるロールモデルの獲得の関連を示した研究を投稿・公刊した。英国Bristol大学との研究では、令和元年8月にSarah Sullivan博士らALSPAC研究チームを招聘し、国際シンポジウムを実施した。日英共同研究に関するアクションプランを策定し、継続的な討議を行っている。米国Fordham大学との研究では，令和元年7月にJordan DeVylder博士を招聘し、セミナーを経て、TTCデータを用いた共同研究を進め、論文化の準備をしている。
リカバリー研究は、令和元年8月に短期派遣研究員1名がCalifornia大学 San Diego校のZiedonis教授の下、リカバリー介入研究の基となる研究成果の実装・普及に関する科学について学んだ。また、精神疾患をもつ人の主体価値の不調からの回復に関するインタビュー調査について解析をすすめ、主体価値からの回復過程とその促進因子を明らかにし、論文執筆、国際学会発表を行った。
海外派遣は、派遣後の研究員4名が研究を継続した。豪国派遣研究員は、TTCや豪国コホートデータを用いた共同研究の継続を、英国派遣研究員1名は、共同研究を継続し、指導者を招聘し連携強化を図り、もう1名は、大規模脳画像データと機械学習技術を用いた個人差の神経基盤理解等の論文投稿を進め、4本投稿うち1本が公刊、オーストリア派遣研究員は、安静時fMRIから報酬予期時の線条体活動の予測モデル構築の共同解析を行った。
上記の通り、当初の予想を上回る成果が得られている。

Strategy for Future Research Activity

コホート共同研究については、今年度に引き続き、共同研究の論文化・公刊を継続して進める。共同研究先（ALSPAC，MRC，Fordham大学）と定期的にウェブミーティングを実施し、進捗確認とディスカッションを行う。今年度中に5件の論文を投稿する予定である。
リカバリー研究については、「思春期精神病理における主体価値の不調からの回復過程の質的研究」について論文化を行い、国際誌に投稿する。また、C01とも連携し若者の困難からの回復過程について調査を行い、より幅広い年代について主体価値の構成概念を抽出していく。また、質的研究により明らかになった回復の促進因子であるピアサポートワーカーによるサポートについて、システマティックレビュー（Ziedonis教授による指導）やインタビューを通して、実装・普及を意識した支援の在り方の明文化を目指す。
海外派遣研究員については、派遣研究を終了した研究員が、各自の研究を進め、結果をまとめ、国際学会発表、専門誌投稿等を進める。また、オーストリア派遣研究員においては、得られた予測モデルの妥当性を検証し、報酬予期を改善する介入法や、その客観的評価指標の開発に貢献することを目指す。
次年度は、C01を主催に当領域で国際シンポジウムを開催する。思春期科学・発達疫学・心理学・精神医学・神経学等の分野で国際的に評価の高い海外研究者2名を招聘し、国際連携ネットワークの構築・強化を推進する。

Research Products

• [Int'l Joint Research] ロンドン大学/ブリストル大学/ケンブリッジ大学(英国)
• [Int'l Joint Research] カリフォルニア大学/フォーダム大学(米国)
• [Int'l Joint Research] トロント大学(カナダ)
• [Int'l Joint Research] メルボルン大学・マードック小児研究所(オーストラリア)
• [Int'l Joint Research] ウィーン大学(オーストリア)
• [Int'l Joint Research] ロンドン大学/ブリストル大学/ケンブリッジ大学(英国)
• [Int'l Joint Research] メルボルン大学/マードック小児研究所(オーストラリア)
• [Int'l Joint Research] トロント大学(カナダ)
• [Int'l Joint Research] ウイーン大学(オーストリア)
• [Int'l Joint Research] ロンドン大学/ブリストル大学/ケンブリッジ大学(英国)
• [Int'l Joint Research] メルボルン大学・マードック小児研究所(豪国)
• [Int'l Joint Research] トロント大学(カナダ)
• [Int'l Joint Research] ウィーン大学(オーストリア)
• [Int'l Joint Research] ロンドン大学/ブリストル大学/ケンブリッジ大学(英国)
• [Int'l Joint Research] メルボルン大学(豪国)
• [Int'l Joint Research] カリフォルニア大学(米国)
• [Journal Article] Use of social networking sites and desire for slimness among 10-year-old girls and boys: A population-based birth cohort study. (2020)
  • Author(s): Sugimoto Noriko、Nishida Atsushi、Ando Shuntaro、Usami Satoshi、Toriyama Rie、Morimoto Yuko、Koike Shinsuke、Yamasaki Syudo、Kanata Sho、Fujikawa Shinya、Furukawa Toshiaki A.、Sasaki Tsukasa、Hiraiwa‐Hasegawa Mariko、Kasai Kiyoto
  • Journal Title: International Journal of Eating Disorder Volume: 53 Pages: 288-295
  • DOI: 10.1002/eat.23202
  • Peer Reviewed / Open Access
• [Journal Article] Global DNA hypomethylation and its correlation to the betaine level in peripheral blood of patients with schizophrenia (2020)
  • Author(s): Murata Y, Ikegame T, Koike S, Saito T, Ikeda M, Sasaki T, Iwata N, Kasai K, Bundo M, Iwamoto K
  • Journal Title: Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume: 99 Pages: 109855-109855
  • DOI: 10.1016/j.pnpbp.2019.109855
  • Peer Reviewed / Open Access
• [Journal Article] Dog and Cat Ownership Predicts Adolescents’ Mental Well-Being: A Population-Based Longitudinal Study (2020)
  • Author(s): Endo Kaori、Yamasaki Syudo、Ando Shuntaro、Kikusui Takefumi、Mogi Kazutaka、Nagasawa Miho、Kamimura Itsuka、Ishihara Junko、Nakanishi Miharu、Usami Satoshi、Hiraiwa-Hasegawa Mariko、Kasai Kiyoto、Nishida Atsushi
  • Journal Title: International Journal of Environmental Research Public Health. Volume: 17 Pages: 3-3
  • DOI: 10.3390/ijerph17030884
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Social withdrawal and testosterone levels in early adolescent boys. (2020)
  • Author(s): Hayashi Noriyuki、Ando Shuntaro、Jinde Seiichiro、Fujikawa Shinya、Okada Naohiro、Toriyama Rie、Masaoka Mio、Sugiyama Hiroshi、Shirakawa Toru、Yagi Tomoko、Morita Masaya、Morishima Ryo、Kiyono Tomoki、Yamasaki Syudo、Nishida Atsushi、Kasai Kiyoto
  • Journal Title: Psychoneuroendocrinology Volume: 116 Pages: 104596-104596
  • DOI: 10.1016/j.psyneuen.2020.104596
  • Peer Reviewed
• [Journal Article] Smaller anterior subgenual cingulate volume mediates the effect of girls' early sexual maturation on negative psychobehavioral outcome (2020)
  • Author(s): Okada N., Yahata N., Koshiyama D., Morita K., Sawada K., Kanata S., Fujikawa S., Sugimoto N., Toriyama R., Masaoka M., Koike S., Araki T., Kano Y., Endo K., Yamasaki S., Ando S., Nishida A., Hiraiwa-Hasegawa M., Kasai K.
  • Journal Title: NeuroImage Volume: 209 Pages: 116478-116478
  • DOI: 10.1016/j.neuroimage.2019.116478
  • Peer Reviewed / Open Access
• [Journal Article] Resting-state EEG beta band power predicts quality of life outcomes in patients with depressive disorders: A longitudinal investigation (2020)
  • Author(s): Koshiyama Daisuke、Kirihara Kenji、Usui Kaori、Tada Mariko、Fujioka Mao、Morita Susumu、Kawakami Shintaro、Yamagishi Mika、Sakurada Hanako、Sakakibara Eisuke、Satomura Yoshihiro、Okada Naohiro、Kondo Shinsuke、Araki Tsuyoshi、Jinde Seichiro、Kasai Kiyoto
  • Journal Title: J Affect Disord Volume: 265 Pages: 416-422
  • DOI: 10.1016/j.jad.2020.01.030
  • Peer Reviewed
• [Journal Article] Gamma-Band Auditory Steady-State Response as a Neurophysiological Marker for Excitation and Inhibition Balance: A Review for Understanding Schizophrenia and Other Neuropsychiatric Disorders (2020)
  • Author(s): Tada M, Kirihara K, Koshiyama D, Fujioka M, Usui K, Uka T, Komatsu M, Kunii N, Araki T, Kasai K.
  • Journal Title: Clinical EEG and Neuroscience Volume: in press
  • DOI: 10.1177/1550059419868872
  • Peer Reviewed
• [Journal Article] Reduced Auditory Mismatch Negativity Reflects Impaired Deviance Detection in Schizophrenia (2020)
  • Author(s): Koshiyama Daisuke、Kirihara Kenji、Tada Mariko、Nagai Tatsuya、Fujioka Mao、Usui Kaori、Araki Tsuyoshi、Kasai Kiyoto
  • Journal Title: Schizophrenia Bulletin Volume: -
  • DOI: 10.1093/schbul/sbaa006
  • Peer Reviewed / Open Access
• [Journal Article] Is Utena's Brief Objective Measures (UBOM) useful in real-world behavioral assessment of functioning? Validity and utility testing in patients with schizophrenia. (2020)
  • Author(s): Sawada Kingo、Sakakibara Eisuke、Kanehara Akiko、Koike Haruna、Suga Motomu、Fujieda Yumiko、Miyamoto Yuki、Fukuda Masato、Kasai Kiyoto
  • Journal Title: Psychiatry and Clinical Neurosciences Volume: 74 Pages: 40-48
  • DOI: 10.1111/pcn.12929
  • Peer Reviewed / Open Access
• [Journal Article] Subcortical Brain Volume Abnormalities in Individuals With an At-risk Mental State (2020)
  • Author(s): Sasabayashi D., Takayanagi Y., Takahashi T., Katagiri N., Sakuma A., Obara C., Katsura M., Okada N., Koike S., Yamasue H., Nakamura M., Furuichi A., Kido M., Nishikawa Y., Noguchi K., Matsumoto K., Mizuno M., Kasai K., Suzuki M.
  • Journal Title: Schizophrenia Bulletin Volume: - Pages: 547-553
  • DOI: 10.1093/schbul/sbaa011
  • Peer Reviewed / Open Access
• [Journal Article] Dopamine D2 receptors in discrimination learning and spine enlargement (2020)
  • Author(s): Iino Yusuke、Sawada Takeshi、Yamaguchi Kenji、Tajiri Mio、Ishii Shin、Kasai Haruo、Yagishita Sho
  • Journal Title: Nature Volume: 579 Pages: 555-560
  • DOI: 10.1038/s41586-020-2115-1
  • Peer Reviewed / Open Access
• [Journal Article] Reliability and validity of the Japanese version of the INSPIRE measure of staff support for personal recovery in community mental health service users in Japan. (2020)
  • Author(s): Kotake Risa、Kanehara Akiko、Miyamoto Yuki、Kumakura Yousuke、Sawada Utako、Takano Ayumi、Chiba Rie、Ogawa Makoto、Kondo Shinsuke、Kasai Kiyoto、Kawakami Norito
  • Journal Title: BMC Psychiatry. Volume: 20 Pages: 51-51
  • DOI: 10.1186/s12888-020-2467-y
  • Peer Reviewed / Open Access
• [Journal Article] White matter microstructural alterations across four major psychiatric disorders: mega-analysis study in 2937 individuals (2020)
  • Author(s): Koshiyama Daisuke、(他38名18番目）Yamamoto Meeri
  • Journal Title: Mol Psychiat Volume: 25 Pages: 883-895
  • DOI: 10.1038/s41380-019-0553-7
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Evaluation of the usefulness of saliva for DNA methylation analysis in cohort studies (2019)
  • Author(s): Murata Yui、Fujii Ayaka、Kanata Sho、Fujikawa Shinya、Ikegame Tempei、Nakachi Yutaka、Zhao Zhilei、Jinde Seiichiro、Kasai Kiyoto、Bundo Miki、Iwamoto Kazuya
  • Journal Title: Neuropsychopharmacology Reports Volume: 39 Pages: 301-305
  • DOI: 10.1002/npr2.12075
  • Peer Reviewed / Open Access
• [Journal Article] Personal values in adolescence and psychological distress in adults: A cross-sectional study based on a retrospective recall. (2019)
  • Author(s): Yasuma Naonori、Watanabe Kazuhiro、Iida Mako、Nishi Daisuke、Kawakami Norito
  • Journal Title: PLoS One Volume: 14
  • DOI: 10.1371/journal.pone.0225454
  • Peer Reviewed / Open Access
• [Journal Article] Predicting ventral striatal activation during reward anticipation from functional connectivity at rest. (2019)
  • Author(s): Mori, Asako, Manfred Klobl, Go Okada, Murray Bruce Reed, Masahiro Takamura, Paul Michenthaler, Koki Takagaki et al.
  • Journal Title: Frontiers in Human Neuroscience Volume: 13 Pages: 289-289
  • DOI: 10.3389/fnhum.2019.00289
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The minimal behavioral time window for reward conditioning in the nucleus accumbens of mice (2019)
  • Author(s): Yamaguchi Kenji、Maeda Yoshitomo、Sawada Takeshi、Iino Yusuke、Tajiri Mio、Nakazato Ryosuke、Kasai Haruo、Yagishita Sho
  • Journal Title: bioRxiv Volume: - Pages: 641365-641365
  • DOI: 10.1101/641365
  • Open Access
• [Journal Article] Altered expression of microRNA-223 in the plasma of patients with first-episode schizophrenia and its possible relation to neuronal migration-related genes (2019)
  • Author(s): Zhao, Zhilei, Seiichiro Jinde, Shinsuke Koike, Mariko Tada, Yoshihiro Satomura, Akane Yoshikawa, Yukika Nishimura et al.
  • Journal Title: Translational Psychiatry Volume: 9 Pages: 289-289
  • DOI: 10.1038/s41398-019-0609-0
  • Peer Reviewed / Open Access
• [Journal Article] Transient and sustained effects of dopamine and serotonin signaling in motivation‐related behavior (2019)
  • Author(s): Yagishita Sho
  • Journal Title: Psychiatry and Clinical Neurosciences Volume: 74 Pages: 91-98
  • DOI: 10.1111/pcn.12942
  • Peer Reviewed / Open Access
• [Journal Article] State-unspecific patterns of whole-brain functional connectivity from resting and multiple task states predict stable individual traits (2019)
  • Author(s): Yu Takagi, Jun-ichiro Hirayama, Saori C. Tanaka
  • Journal Title: NeuroImage Volume: 201 Pages: 116036-116036
  • DOI: 10.1016/j.neuroimage.2019.116036
  • Peer Reviewed / Open Access
• [Journal Article] Functional connectome linking child-parent relationships with psychological problems in adolescence (2019)
  • Author(s): Itahashi Takashi、Okada Naohiro、Ando Shuntaro、Yamasaki Syudo、Koshiyama Daisuke、Morita Kentaro、Yahata Noriaki、Koike Shinsuke、Nishida Atsushi、Kasai Kiyoto、Hashimoto Ryu-ichiro
  • Journal Title: bioRxiv Volume: -
  • DOI: 10.1101/678714
  • Open Access
• [Journal Article] Individualized Prediction of Transition to Psychosis in 1,676 Individuals at Clinical High Risk: Development and Validation of a Multivariable Prediction Model Based on Individual Patient Data Meta-Analysis (2019)
  • Author(s): Malda, Aaltsje, Nynke Boonstra, Hans Barf, Steven De Jong, Andre Aleman, Jean Addington, Marita Pruessner et al.
  • Journal Title: Frontiers in Psychiatry Volume: 10
  • DOI: 10.3389/fpsyt.2019.00345
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Gamma-band auditory steady-state response is associated with plasma levels of d-serine in schizophrenia: An exploratory study (2019)
  • Author(s): Koshiyama Daisuke、Kirihara Kenji、Tada Mariko、Nagai Tatsuya、Fujioka Mao、Usui Kaori、Koike Shinsuke、Suga Motomu、Araki Tsuyoshi、Hashimoto Kenji、Kasai Kiyoto
  • Journal Title: Schizophrenia Research Volume: 208 Pages: 467-469
  • DOI: 10.1016/j.schres.2019.02.012
  • Peer Reviewed / Open Access
• [Journal Article] Age relative to school class peers and emotional well-being (2019)
  • Author(s): Shuntaro Ando , Satoshi Usami, Tetsuya Matsubayashi, Michiko Ueda, Shinsuke Koike, Syudo Yamasaki, Shinya Fujikawa, Tsukasa Sasaki, Mariko Hiraiwa-Hasegawa, George Patton, Kiyoto Kasai, Atsushi Nishida
  • Journal Title: PLOS ONE Volume: 14 (3)
  • DOI: 10.1371/journal.pone.0214359
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Severity-dependent and -independent brain regions of major depressive disorder: A long-term longitudinal near-infrared spectroscopy study (2019)
  • Author(s): Satomura Yoshihiro、Sakakibara Eisuke、Takizawa Ryu、Koike Shinsuke、Nishimura Yukika、Sakurada Hanako、Yamagishi Mika、Shimojo Chie、Kawasaki Shingo、Okada Naohiro、Matsuoka Jun、Kinoshita Akihide、Jinde Seiichiro、Kondo Shinsuke、Kasai Kiyoto
  • Journal Title: Journal of Affective disorder Volume: 243 Pages: 249-254
  • DOI: 10.1016/j.jad.2018.09.029
  • Peer Reviewed
• [Journal Article] Cohort Profile: The Tokyo Teen Cohort study (TTC). (2019)
  • Author(s): Ando Shuntaro、Nishida Atsushi、Yamasaki Syudo、Koike Shinsuke、Morimoto Yuko、Hoshino Aya、Kanata Sho、Fujikawa Shinya、Endo Kaori、Usami Satoshi、Furukawa Toshiaki A、Hiraiwa-Hasegawa Mariko、Kasai Kiyoto、TTC Scientific and Data Collection Team
  • Journal Title: Int J Epidemiol Volume: dzy033 Pages: 1414-1414
  • DOI: 10.1093/ije/dyz033
  • Peer Reviewed / Open Access
• [Journal Article] Maternal diabetes in early pregnancy, and psychotic experiences and depressive symptoms in 10-year-old offspring: A population-based birth cohort study. (2019)
  • Author(s): Syudo Yamasaki, Shuntaro Ando, Marcus Richards, Stephani L.Hatch, Shinsuke Koike ,Shinya Fujikawa, Sho Kanata, Kaori Endo, Yuko Morimoto, Makoto Arai, Haruo Okado, Satoshi Usami, Toshiaki A.Furukawa, Mariko Hiraiwa-Hasegawa, Kiyoto Kasai, Atsushi Nishida
  • Journal Title: Schizophr Res. Volume: 印刷中 Pages: 30704-30707
  • DOI: 10.1016/j.schres.2018.12.016
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Population-neuroscience study of the Tokyo TEEN Cohort (pn-TTC) : Cohort longitudinal study to explore the neurobiological substrates of adolescent psychological and behavioral development (2019)
  • Author(s): Okada N., Ando S., Sanada M., Hirata-Mogi S., Iijima Y., Sugiyama H., Shirakawa T., Yamagishi M., Kanehara A., Morita M., Yagi T., Hayashi N., Koshiyama D., Morita K., Sawada K., Ikegame T., Sugimoto N., Toriyama R., Masaoka M., Fujikawa S., Kanata S., Tada M., Kirihara K., Yahata N., Araki T., Jinde S., Kano Y., Koike S., Endo K., Yamasaki S., Nishida A., Hiraiwa-Hasegawa M., Bundo M., Iwamoto K., Tanaka SC., Kasai K.
  • Journal Title: Psychiatry and Clinical Neurosciences Volume: 印刷中 Pages: 231-242
  • DOI: 10.1111/pcn.12814
  • Peer Reviewed / Open Access
• [Journal Article] Neurometabolic and functional connectivity basis of prosocial behavior in early adolescence (2019)
  • Author(s): Okada N., Yahata N., Koshiyama D., Morita K., Sawada K., Kanata S., Fujikawa S., Sugimoto N., Toriyama R., Masaoka M., Koike S., Araki T., Kano Y., Endo K., Yamasaki S., Ando S., Nishida A., Hiraiwa-Hasegawa M., Edden R. A. E., Barker P. B., Sawa A., Kasa
  • Journal Title: Scientific Reports Volume: 9 Pages: 732-732
  • DOI: 10.1038/s41598-018-38355-z
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Surface morphology of the orbitofrontal cortex in individuals at risk of psychosis : a multicenter study (2019)
  • Author(s): Nakamura M., Takahashi T., Takayanagi Y., Sasabayashi D., Katagiri N., Sakuma A., Obara C., Koike S., Yamasue H., Furuichi A., Kido M., Nishikawa Y., Noguchi K., Matsumoto K., Mizuno M., Kasai K., Suzuki M.
  • Journal Title: European Archives of Psychiatry and Clinical Neuroscience Volume: - Pages: 397-406
  • DOI: 10.1007/s00406-018-0890-6
  • Peer Reviewed / Open Access
• [Journal Article] The impact of being bullied at school on psychological distress and work engagement in a community sample of adult workers in Japan (2018)
  • Author(s): Kasai Kiyoto, Fukuda Masato
  • Journal Title: PlosOne Volume: 3 Pages: 14-14
  • DOI: 10.1038/s41537-017-0016-6
  • Peer Reviewed / Open Access
• [Journal Article] Lack of correlation between phonetic magnetic mismatch field and plasma d-serine levels in humans (2018)
  • Author(s): Motomu Suga, Yuki Kawakubo,Yukika Nishimura, Kenji Hashimoto, Masato Yumoto, Kiyoto Kasai
  • Journal Title: Clinical Neurophysiology Volume: 129 (7) Pages: 1444-1448
  • DOI: 10.1016/j.clinph.2018.04.603
  • Peer Reviewed
• [Journal Article] Lithium levels in tap water and psychotic experiences in a general population of adolescents. (2018)
  • Author(s): Shinji Shimodera, Shinsuke Koike, Shuntaro Ando, SyudoYamasaki, Ryosuke Fujito, Kaori Endo, Yudai Iijima, Yu Yamamot, Masaya Morita, Ken Sawada, Nobuki Ohara, Yuji Okazaki, Atsushi Nishida
  • Journal Title: Schizophr Res. Volume: 2011 Pages: 294-298
  • DOI: 10.1016/j.schres.2018.05.019
  • Peer Reviewed / Open Access
• [Journal Article] Genetic influences on prefrontal activation during a verbal fluency task in children: A twin study using near‐infrared spectroscopy (2018)
  • Author(s): Eisuke Sakakibara, Ryu Takizawa, Yuki Kawakubo, Hitoshi Kuwabara, Toshiaki Kono. Kasumi Hamada. Shiho Okuhata. Satoshi Eguchi, Ayaka Ishii‐Takahashi, Kiyoto Kasai
  • Journal Title: Brain and Behavior Volume: 8 (6)
  • NAID: 120006496949
  • Peer Reviewed / Open Access
• [Journal Article] Help-seeking intention for depression in early adolescents: Associated factors and sex differences. (2018)
  • Author(s): Ando Shuntaro、Nishida Atsushi、Usami Satoshi、Koike Shinsuke、Yamasaki Syudo、Kanata Sho、Fujikawa Shinya、Furukawa Toshiaki A、Fukuda Masato、Sawyer Susan M、Hiraiwa-Hasegawa Mariko、Kasai Kiyoto
  • Journal Title: J Affect Disord Volume: 238 Pages: 359-365
  • DOI: 10.1016/j.jad.2018.05.077
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Diffusional kurtosis imaging and white matter microstructure modeling in a clinical study of major depressive disorder (2018)
  • Author(s): Kamiya K., Okada N., Sawada K., Watanabe Y., Irie R., Hanaoka S., Suzuki Y., Koike S., Mori H., Kunimatsu A., Hori M., Aoki S., Kasai K., Abe O.
  • Journal Title: NMR Biomed Volume: 31
  • DOI: 10.1002/nbm.3938
  • Peer Reviewed / Open Access
• [Journal Article] Disciplinary slapping is associated with bullying involvement regardless of warm parenting in early adolescence. (2018)
  • Author(s): Fujikawa Shinya、Ando Shuntaro、Nishida Atsushi、Usami Satoshi、Koike Shinsuke、Yamasaki Syudo、Morimoto Yuko、Toriyama Rie、Kanata Sho、Sugimoto Noriko、Sasaki Tsukasa、Furukawa Toshiaki A.、Hiraiwa-Hasegawa Mariko、Kasai Kiyoto
  • Journal Title: J Adolesc Volume: 68 Pages: 207-216
  • DOI: 10.1016/j.adolescence.2018.07.018
  • Peer Reviewed
• [Journal Article] Purpose in life and tobacco use among community-dwelling mothers of early adolescents. (2018)
  • Author(s): Morimoto Y*, Yamasaki S*, Ando S, Koike S, Fujikawa S, Kanata S, Endo K, Nakanishi M, Hatch SL, Richards M, Kasai K, Hiraiwa-Hasegawa M, Nishida A (*equal contribution)
  • Journal Title: BMJ Open. Volume: 8
  • DOI: 10.1136/bmjopen-2017-020586
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Electrophysiological evidence for abnormal glutamate-GABA association following psychosis onset (2018)
  • Author(s): Koshiyama Daisuke、Kirihara Kenji、Tada Mariko、Nagai Tatsuya、Fujioka Mao、Ichikawa Eriko、Ohta Kazusa、Tani Motoko、Tsuchiya Maiko、Kanehara Akiko、Morita Kentaro、Sawada Kingo、Matsuoka Jun、Satomura Yoshihiro、Koike Shinsuke、Suga Motomu、Araki Tsuyoshi、Kasai Kiyoto
  • Journal Title: Translational Psychiatry Volume: 8 Pages: 211-211
  • DOI: 10.1038/s41398-018-0261-0
  • Peer Reviewed / Open Access
• [Journal Article] Abnormal asymmetries in subcortical brain volume in early adolescents with subclinical psychotic (2018)
  • Author(s): Okada N., Yahata N., Koshiyama D., Morita K., Sawada K., Kanata S., Fujikawa S., Sugimoto N., Toriyama R., Masaoka M., Koike S., Araki T., Kano Y., Endo K., Yamasaki S., Ando S., Nishida A., Hiraiwa-Hasegawa M., Kasai K.
  • Journal Title: Transl Psychiatry Volume: 8 Pages: 254-254
  • DOI: 10.1038/s41398-018-0312-6
  • Peer Reviewed / Open Access
• [Journal Article] The association between changes in depression/anxiety and trajectories of psychotic-like experiences over a year in adolescence. (2018)
  • Author(s): Yamasaki Syudo, Usami Satoshi, Sasaki Ryo, Koike Shinsuke, Ando Shuntaro, Kitagawa Yuko, Matamura Misato, Fukushima Masako, Yonehara Hiromi, Foo Jerome Clifford, Nishida Atsushi, Sasaki Tsukasa
  • Journal Title: Schizophr Res. Volume: - Pages: 149-153
  • DOI: 10.1016/j.schres.2017.10.019
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Role of subcortical structures on cognitive and social function in schizophrenia (2018)
  • Author(s): Koshiyama D., Fukunaga M., Okada N., Yamashita F., Yamamori H., Yasuda Y., Fujimoto M., Ohi K., Fujino H., Watanabe Y., Kasai K., Hashimoto R.
  • Journal Title: Scientific Reports Volume: 8 Pages: 1183-1183
  • DOI: 10.1038/s41598-017-18950-2
  • Peer Reviewed / Open Access
• [Journal Article] Subcortical association with memory performance in schizophrenja : a structural magnetic resonance imaging study (2018)
  • Author(s): Koshiyama D., Fukunaga M., Okada N., Yamashita F., Yamamori H., Yasuda Y., Fujimoto M., Ohi K., Fujino H., Watanabe Y., Kasai K., Hashimoto R.
  • Journal Title: Transl Psychiatry Volume: 8 Pages: 1-11
  • DOI: 10.1038/s41398-017-0069-3
  • Peer Reviewed / Open Access
• [Journal Article] Mutations of the glycine cleavage system genes possibly affect the negative symptoms of schizophrenia through metabolomic profile changes. (2018)
  • Author(s): Yoshikawa Akane, Nishimura Fumichika, Inai Aya, Eriguchi Yosuke, Nishioka Masaki, Takaya Atsuhiko, Tochigi Mamoru, Kawamura Yoshiya, Umekage Tadashi, Kato Kayoko, Sasaki Tsukasa, Ohashi Yoshiaki, Iwamoto Kazuya, Kasai Kiyoto, Kakiuchi Chihiro
  • Journal Title: Psychiatry Clin Neurosci Volume: 72 Pages: 168-179
  • DOI: 10.1111/pcn.12628
  • Peer Reviewed / Open Access
• [Journal Article] Association between mismatch negativity and global functioning is specific to duration deviance in early stages of psychosis. (2018)
  • Author(s): Koshiyama Daisuke, Kirihara Kenji, Tada Mariko, Nagai Tatsuya, Fujioka Mao, Koike Shinsuke, Suga Motomu, Araki Tsuyoshi, Kasai Kiyoto
  • Journal Title: Schizophr Res Volume: - Pages: 30607-30607
  • DOI: 10.1016/j.schres.2017.09.045
  • Peer Reviewed / Open Access
• [Journal Article] Novel rare variations in genes which regulate the developmental change in N-Methyl-D-Aspartate receptor in patients with schizophrenia (2018)
  • Author(s): Yoshikawa Akane, Nishimura Fumichika, Inai Aya, Eriguchi Yosuke, Nishioka Masaki, Takaya Atsuhiko, Tochigi Mamoru, Kawamura Yoshiya, Umekage Tadashi, Kato Kayoko, Sasaki Tsukasa, Kasai Kiyoto, Kakiuchi Chihiro
  • Journal Title: Hum Genome Volume: 5 Pages: 17056-17056
  • DOI: 10.1038/hgv.2017.56
  • Peer Reviewed / Open Access
• [Journal Article] Coping mediates the association between empathy and psychological distress among Japanese workers (2018)
  • Author(s): Isobe Masanori、Redden Sarah A.、Keuthen Nancy J.、Stein Dan J.、Lochner Christine、Grant Jon E.、Chamberlain Samuel R.
  • Journal Title: Personality and Individual Differences Volume: 17 Pages: 178-183
  • DOI: 10.1016/j.nicl.2017.12.031
  • NAID: 120006425873
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Strengthening community mental health services in Japan (2017)
  • Author(s): Kasai K, Ando S, Kanehara A, Kumakura Y, Kondo S, Fukuda M, Kawakami N, Higuchi T.
  • Journal Title: Lancet Psychiatry Volume: 4 Pages: 267-270
  • DOI: 10.1016/s2215-0366(16)30373-x
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Sex differences in auditory verbal hallucinations in early, middle and late adolescence: results from a survey of 17 451 Japanese students aged 12-18 years. (2017)
  • Author(s): Morokuma Yoko, Endo Kaori, Nishida Atushi, Yamasaki Syudo, Ando Shuntaro, Morimoto Yuko, Nakanishi Miharu, Okazaki Yuji, Furukawa Toshi A, Morinobu Shigeru, Shimodera Shinji
  • Journal Title: BMJ Open Volume: 7
  • DOI: 10.1136/bmjopen-2016-015239
  • Peer Reviewed / Open Access
• [Journal Article] The Japanese version of the questionnaire about the process of recovery: development and validity and reliability testing. (2017)
  • Author(s): Kanehara Akiko, Kotake Risa, Miyamoto Yuki, Kumakura Yousuke, Morita Kentaro, Ishiura Tomoko, Shimizu Kimiko, Fujieda Yumiko, Ando Shuntaro, Kondo Shinsuke, Kasai Kiyoto
  • Journal Title: BMC Psychiatry Volume: 17 Pages: 360-360
  • DOI: 10.1186/s12888-017-1520-y
  • Peer Reviewed / Open Access
• [Journal Article] Application of functional near infrared spectroscopy as supplementary examination for diagnosis of clinical stages of psychosis spectrum (2017)
  • Author(s): Koike S., Satomura Y., Kawasaki S., Nishimura Y., Kinoshita A., Sakurada H., Yamagishi M., Ichikawa E., Matsuoka J., Okada N., Takizawa R., Kasai K.
  • Journal Title: Psychiatry and Clinical Neurosciences Volume: 71 Pages: 794-806
  • DOI: 10.1111/pcn.12551
  • Peer Reviewed / Open Access
• [Journal Article] Increased Occipital Gyrification and Development of Psychotic Disorders in Individuals With an At-Risk Mental State : A Multicenter Study (2017)
  • Author(s): Sasabayashi D., Takayanagi Y., Takahashi T., Koike S., Yamasue H., Katagiri N., Sakuma A., Obara C., Nakamura M., Furuichi A., Kido M., Nishikawa Y., Noguchi K., Matsumoto K., Mizuno M., Kasai K., Suzuki M.
  • Journal Title: Biological Psychiatry Volume: 82 Pages: 737-745
  • DOI: 10.1016/j.biopsych.2017.05.018
  • Peer Reviewed / Open Access
• [Journal Article] Premature deaths among individuals with severe mental illness after discharge from long-term hospitalization in Japan: a naturalistic observation during a 24-year period. (2017)
  • Author(s): Kondo Shinsuke, Kumakura Yousuke, Kanehara Akiko, Nagato Daisuke, Ueda Taro, Matsuoka Tsuneo, Tao Yukiko, Kasai Kiyoto
  • Journal Title: BJPsych Open Volume: 3 Pages: 193-195
  • DOI: 10.1192/bjpo.bp.117.004937
  • Peer Reviewed / Open Access
• [Journal Article] Associations between daily living skills, cognition, and real-world functioning across stages of schizophrenia; a study with the Schizophrenia Cognition Rating Scale Japanese version (2017)
  • Author(s): Higuchi Y, Sumiyoshi T, Seo T, Suga M, Takahashia T, Nishiyama S, Komori Y, Kasai K, Suzuki M
  • Journal Title: Schizophr Res Cogn Volume: 7 Pages: 13-18
  • DOI: 10.1016/j.scog.2017.01.001
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Reduced mismatch negativity is associated with increased plasma level of glutamate in first-episode psychosis (2017)
  • Author(s): Nagai Tatsuya, Kirihara Kenji, Tada Mariko, Koshiyama Daisuke, Koike Shinsuke, Suga Motomu, Araki Tsuyoshi, Hashimoto Kenji, Kasai Kiyoto
  • Journal Title: Sci Rep Volume: 7 Pages: 2258-2258
  • DOI: 10.1038/s41598-017-02267-1
  • Peer Reviewed / Open Access
• [Journal Article] Estimated cognitive decline in patients with schizophrenia: A multicenter study (2017)
  • Author(s): Fujino H, Sumiyoshi C, Yasuda Y, Yamamori H, Fujimoto M, Fukunaga M, Miura K, Takebayashi Y, Okada N, Isomura S, Kawano N, Toyomaki A, Kuga H, Isobe M, Oya K, Okahisa Y, Takaki M, Hashimoto N, Kato M, Onitsuka T, Ueno T, Ohnuma T, Kasai K, Ozaki N, Sumiyoshi T, Imura O, Hashimoto R
  • Journal Title: Psychiatry and Clinical Neurosciences Volume: 印刷中 Pages: 294-300
  • DOI: 10.1111/pcn.12474
  • Peer Reviewed / Open Access
• [Journal Article] Crowdsourced identification of possible allergy associated factors: automated hypothesis generation and validation using a crowdsourcing services (2017)
  • Author(s): Aramaki, E., Shikata, S., Ayaya, S., & Kumagaya, S.
  • Journal Title: JMIR Research Protocols Volume: 6(5)
  • DOI: 10.2196/resprot.5851
  • Peer Reviewed / Open Access
• [Journal Article] Duration and frequency mismatch negativity shows no progressive reduction in early stages of psychosis. (2017)
  • Author(s): Koshiyama D, Kirihara K, Tada M, Nagai T, Koike S, Suga M, Araki T, Kasai K
  • Journal Title: Schizophr Res Volume: 印刷中 Pages: 32-38
  • DOI: 10.1016/j.schres.2017.03.015
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Identifying neurocognitive markers for outcome prediction of global functioning in individuals with first-episode and ultra-high-risk for psychosis (2017)
  • Author(s): Sawada K, Kanehara A, Eguchi S, Tada M, Satomura Y, Suga M, Koike S, Kasai K
  • Journal Title: Psychiatry Clin Neurosci Volume: 印刷中 Pages: 318-327
  • DOI: 10.1111/pcn.12522
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Mental health problems in a community after the Great East Japan Earthquake in 2011: a systematic review (2017)
  • Author(s): Ando S, Kuwabara H, Araki T, Kanehara A, Tanaka S, Morishima R, Kondo S, Kasai K
  • Journal Title: Harvard Review of Psychiatry Volume: 25 Pages: 15-28
  • DOI: 10.1097/hrp.0000000000000124
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Eye movement as a biomarker of schizophrenia: using an integrated eye movement score. (2017)
  • Author(s): Morita K, Miura K, Fujimoto M, Yamamori H, Yasuda Y, Iwase M, Kasai K, Hashimoto R.
  • Journal Title: Psychiatry and Clinical Neurosciences Volume: 71(2) Pages: 104-114
  • DOI: 10.1111/pcn.12460
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Trends in psychological distress and alcoholism after The Great East Japan Earthquake of 2011 (2016)
  • Author(s): Kanehara A, Ando S, Araki T, Usami S, Kuwabara H, Kano Y, Kasai K
  • Journal Title: SSM - Population Health Volume: 2 Pages: 807-812
  • DOI: 10.1016/j.ssmph.2016.10.010
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] The Association of Current Violence from Adult Family Members with Adolescent Bullying Involvement and Suicidal Feelings (2016)
  • Author(s): Fujikawa S, Ando S, Shimodera S, Koike S, Usami S, , Kasai K, Okazaki Y, Nishida A.
  • Journal Title: Plos One Volume: 11(10)
  • DOI: 10.1371/journal.pone.0163707
  • NAID: 120005893645
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] リカバリーの意味とその科学 (2016)
  • Author(s): 笠井 清登
  • Journal Title: 精神神経学雑誌 Volume: 118 Pages: 744-749
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] 安静時脳結合による報酬予測時の腹側線条体活動予測 (2019)
  • Author(s): 森 麻子，岡田 剛，高村真広，高垣耕企，横山仁史，市川奈穂，柴崎千代，吉野敦雄，岡本泰昌，山脇成人
  • Organizer: 第41回日本生物学的精神医学会
• [Presentation] うつの報酬予期障害に関する脳機能画像研究 (2019)
  • Author(s): 森 麻子，岡田 剛，岡本泰昌
  • Organizer: 第41回日本生物学的精神医学会
• [Presentation] 思春期発来前後での思春期精神病症状体験と自殺関連行動・抑うつ症状の関係～思春期出生コホートによるエビデンス (2019)
  • Author(s): 山崎修道、安藤俊太郎、遠藤香織、小池進介、長谷川眞理子、笠井清登、西田淳志
  • Organizer: 第14回日本統合失調症学会
• [Presentation] INDIGO READ研究の紹介と日本サイトでの実践 (2019)
  • Author(s): 安藤俊太郎、山口創生、小川亮、小塩靖崇、市橋香代、近藤伸介、藤井千代、笠井清登
  • Organizer: 第115回日本精神神経学会
• [Presentation] 児童思春期における微量なリチウム摂取とメンタルヘルス (2019)
  • Author(s): 安藤俊太郎、西田淳志、山﨑修道、笠井清登
  • Organizer: 第115回日本精神神経学会
• [Presentation] 相対年齢とウエルビーイングの関係：媒介要因の検討 (2019)
  • Author(s): 安藤俊太郎
  • Organizer: 第60回日本児童青年精神医学会総会
• [Presentation] 母子保健と思春期精神保健を連続的にとらえた地域保健戦略：母子手帳の科学的活用 (2019)
  • Author(s): 西田淳志
  • Organizer: 第60回日本児童青年精神医学会総会
• [Presentation] 日本におけるChildren with Special Health Care Needs (2019)
  • Author(s): 梶奈美子
  • Organizer: 第60回日本児童青年精神医学会総会
• [Presentation] 養育といじめの関連の縦断的検討：Tokyo Teen Cohort study (2019)
  • Author(s): 藤川慎也
  • Organizer: 第60回日本児童青年精神医学会総会
• [Presentation] The concept and facilitators of personal recovery for mental health service users in Japan. (2019)
  • Author(s): Kanehara A, Koike H, Fujieda Y, Yajima S, Kabumoto A, Morita K, Kumakura Y, Kanata S, Nochi M, Kasai K
  • Organizer: 7th European Conference on Schizophrenia Research
  • Int'l Joint Research
• [Presentation] Using translatable brain markers to understand pathophysiology of early psychosis. International symposium on redox in psychosis risk. (2019)
  • Author(s): Kasai K
  • Organizer: -
  • Int'l Joint Research
• [Presentation] Asian Consortium on MRI studies in Psychosis project. (2019)
  • Author(s): Kasai K
  • Organizer: AsCNP
  • Int'l Joint Research
• [Presentation] Neurometabolic basis of subclinical psychotic experiences in early adolescents. (2019)
  • Author(s): Okada N, Yahata N, Koike S, Ando S, Nishida A, Kasai K
  • Organizer: AsCNP
  • Int'l Joint Research
• [Presentation] Support for adolescents and young adults (AYA) with 22q11.2 deletion syndrome. (2019)
  • Author(s): Kumakura Y, Hamada J, Ogawa T, Kanehara A, Morishima R, Noriko O, Fukuda M, Kasai K
  • Organizer: 7th European Conference on Schizophrenia Research
  • Int'l Joint Research
• [Presentation] Psychopathological symptoms associated with global functional outcome in ultra-high-risk individual and patients with first-episode psychosis. (2019)
  • Author(s): Usui K, Kirihara K, Tada M, Fujioka M, Koshiyama D, Koike S, Araki T, Kasai K
  • Organizer: 7th European Conference on Schizophrenia Research
  • Int'l Joint Research
• [Presentation] Neurometabolic basis of subclinical psychotic experiences in early adolescents. (2019)
  • Author(s): Okada N, Yahata N, Koike S, Ando S, Nishida A, Kasai K
  • Organizer: 7th European Conference on Schizophrenia Research
  • Int'l Joint Research
• [Presentation] Personalized intervention in psychiatric disorders: bio-typing neuromodulation and response prediction. (2019)
  • Author(s): Kasai K, Kwon JS
  • Organizer: 7th BESETO International Psychiatry Conference
  • Int'l Joint Research
• [Presentation] Anti-NMDA Receptor Encephalitis Initially Diagnosed as Hashimoto Encephalopathy. (2019)
  • Author(s): Azuma H, Tanaka R, Nakai M, Araki T, Koguchi A, Mitsutake A, Toda T, Kondo S, Kasai K
  • Organizer: 7th BESETO International Psychiatry Conference
  • Int'l Joint Research
• [Presentation] Image analysis on discrepancy between subjective and objective evaluation of depression: Resting-state fMRI study. (2019)
  • Author(s): Kawakami S, Okada N, Morita K, Koshiyama T, Morita S, Kasai K
  • Organizer: 7th BESETO International Psychiatry Conference
  • Int'l Joint Research
• [Presentation] Living in temporary housing and psychological distress after the Great East Japan Earthquake. (2019)
  • Author(s): Morishima R, Ando S, Araki T, Usami S, Kasai K
  • Organizer: 7th BESETO International Psychiatry Conference
  • Int'l Joint Research
• [Presentation] Machine learning-based prediction of schzophrenia spectrum. (2019)
  • Author(s): Zhu Y, Nakatani H, Yassin W, Okada N, Abe O, Yamasue H, Kasai K, Koike S
  • Organizer: 7th BESETO International Psychiatry Conference
  • Int'l Joint Research
• [Presentation] Characterization of Cerebellar structures and its relationship with clinical symptoms in schizophrenia and autism spectrum disorder. (2019)
  • Author(s): Morimoto C, Yamasue H, Kasai K, Koike S
  • Organizer: 7th BESETO International Psychiatry Conference
  • Int'l Joint Research
• [Presentation] Autism spectrum and psychotic experiences. (2019)
  • Author(s): Kiyono T, Morita M, Morishima R, Ando S, Kasai K
  • Organizer: 7th BESETO International Psychiatry Conference
  • Int'l Joint Research
• [Presentation] Longitudinal relations between psychopathological symptoms and global functional outcome in ultra-high-risk individuals and patients with first-episode psychosis. (2019)
  • Author(s): Usui K, Kirihara K, Tada M, Fujioka M, Koshiyama D, Koike S, Suga M, Araki T, Kasai K
  • Organizer: 7th BESETO International Psychiatry Conference
  • Int'l Joint Research
• [Presentation] Mismatch negativity predicts remission and neurocognitive function in individuals at ultra-high risk for psychosis. (2019)
  • Author(s): Fujioka M, Kirihara K, Koshiyama D, Tada M, Nagai T, Usui K, Koike S, Suga M, Araki T, Kasai K
  • Organizer: 7th BESETO International Psychiatry Conference
  • Int'l Joint Research
• [Presentation] Sleep duration and psychotic syomptons in adolescents: Findings from the population-based study. (2019)
  • Author(s): Morishima R, Yamasaki S, Ando S, Shimodera S, Ojio Y, Okazaki Y, Kasai K, Sasaki T, Nishida A
  • Organizer: 7th BESETO International Psychiatry Conference
  • Int'l Joint Research
• [Presentation] Translatable neurophysiological & neuroanatomical markers for psychosis. (2019)
  • Author(s): Kasai K
  • Organizer: NCCR-IRCN “22q” Workshop
  • Int'l Joint Research
• [Presentation] Model abstraction for model-based reinforcement learning in the human orbitofrontal cortex (2019)
  • Author(s): Takagi Y, Yoshida W, Tanaka C. S
  • Organizer: 2019 Conference on Cognitive Computational Neuroscience
  • Int'l Joint Research
• [Presentation] 思春期のこころの成長と不調からの回復． (2019)
  • Author(s): 笠井清登
  • Organizer: 脳とこころの研究 第4回公開シンポジウム
• [Presentation] 閾値下精神病体験を認める思春期早期の児における脳皮質下体積の左右バランスの変化に関する検討． (2019)
  • Author(s): 笠井清登
  • Organizer: 脳とこころの研究 第4回公開シンポジウム
• [Presentation] The difference in brain activity of the prefrontal cortex between schizophrenia, bipolar disorder, and major depression. (2018)
  • Author(s): Koike S, Sakakibara E, Satomura Y, Sakurada H, Yamagishi M, Matsuoka J, Okada N, Kasai K
  • Organizer: WFSBP Asia Pacific Regional Congress of Biological Psychiatry
  • Int'l Joint Research
• [Presentation] Investigation of abnormal molecular pathways in LINE-1 regulation in the brain using embryonic poly(I:C) model mouse. (2018)
  • Author(s): Murata Y, Bundo M, Ueda J, Ohnishi A, Kubota-Sakashita M, Ikegame T, Suhara T, Kasai K, Kato T, Iwamoto K
  • Organizer: WFSBP Asia Pacific Regional Congress of Biological Psychiatry
  • Int'l Joint Research
• [Presentation] Circuits/physiology biomarkers based on RDoC. (2018)
  • Author(s): Okada N, Hashimoto R, Ozaki N, Kasai K
  • Organizer: WFSBP Asia Pacific Regional Congress of Biological Psychiatry
  • Int'l Joint Research
• [Presentation] Mismatch negativity in schizophrenia. (2018)
  • Author(s): Araki T, Kirihara K, Koshiyama D, Nagai T, Tada M, Fujioka M, Usui K, Kasai K
  • Organizer: WFSBP Asia Pacific Regional Congress of Biological Psychiatry
  • Int'l Joint Research
• [Presentation] Neuroimaging and neurophysiological investigations into schizophrenia. (2018)
  • Author(s): Kasai K
  • Organizer: RIKEN CBS Summer Program 2018
  • Int'l Joint Research / Invited
• [Presentation] ARMS群における大脳皮質厚の変化と機能的転帰との関連 (2018)
  • Author(s): 笹林大樹、高柳陽一郎、高橋努、小森祐子、片桐直之、佐久間篤、小原千佳、小池進介、中村美保子、古市厚志、木戸幹雄、西川祐美子、野口京、山末英典、松本和紀、水野雅文、笠井清登、鈴木道雄
  • Organizer: 第22回日本精神保健・予防学会学術集会
• [Presentation] 今後の多施設共同研究における早期精神病の評価・診断のあり方． (2018)
  • Author(s): 多田真理子、小池進介、笠井清登
  • Organizer: 第22回日本精神保健・予防学会学術集会
• [Presentation] 人生行動科学にもとづく統合失調症の理解と支援 (2018)
  • Author(s): 笠井清登
  • Organizer: 第4回九州DPAフォーラム
  • Invited
• [Presentation] あなたの価値観を大切にする統合失調症の新しい理解と支援 (2018)
  • Author(s): 笠井清登
  • Organizer: 第53回コンボ亭月例会
• [Presentation] 5HTTLPRのハイスループットジェノタイピング法による新規多型の同定． (2018)
  • Author(s): 日高洋介、池亀天平、菅原裕子、清田恵美、笠井清登、石川智久、橋本衛、竹林実、文東美紀、岩本和也
  • Organizer: 第48回日本神経精神薬理学会
• [Presentation] 精神疾患のリバーストランスレーショナルリサーチ． (2018)
  • Author(s): 笠井清登
  • Organizer: 第34回Wakoワークショップ
• [Presentation] 精神病発症危険群における脳回形成の変化と認知機能障害との関連． (2018)
  • Author(s): 笹林大樹、高柳陽一郎、高橋努、小森祐子、西山志満子、片桐直之、佐久間篤、小原千佳、小池進介、山末英典、中村美保子、古市厚志、木戸幹雄、西川祐美子、笠井清登、松本和紀、水野雅文、鈴木道雄．
  • Organizer: 第18回精神疾患と認知機能研究会．
• [Presentation] ミスマッチ陰性電位は精神病ハイリスク者の寛解をよび認知機能を予測する． (2018)
  • Author(s): 藤岡真生、切原賢治、越山太輔、多田真理子、永井達哉、臼井香、小池進介、管心、荒木剛、笠井清登
  • Organizer: 第18回精神疾患と認知機能研究会
• [Presentation] Neurophysiological investigations into early psychosis using translatable brain markers. (2018)
  • Author(s): Kasai K
  • Organizer: The 40th Annual Meeting of Japanese Society of Biological Psychiatry
• [Presentation] Mismatch negativity as a translatable biomarker bridging a gap between animal model and human diseases. (2018)
  • Author(s): Kiyoto Kasai, Gregory A. Light
  • Organizer: The 41st Annual Meeting of the Japan Neuroscience Society,
• [Presentation] MMN in human adolescence and in early psychosis. (2018)
  • Author(s): Koshiyama D, Kirihara K, Tada M, Nagai T, Fujioka M, Usui K, Koike S, Suga M, Araki T, Kasai K
  • Organizer: The 41st Annual Meeting of the Japan Neuroscience Society,
• [Presentation] Human ECoG study on the lateral superior temporal gyrus: deviance detection versus adaptation. (2018)
  • Author(s): Kunii N, Ishishita Y, Shimada S, Tada M, Kirihara K, Uka T, Kasai K, Saito N
  • Organizer: The 41st Annual Meeting of the Japan Neuroscience Society,
• [Presentation] Developing a method for detection of LINE-1 and its application to single brain cells. (2018)
  • Author(s): Bundo M, Ueda J, Nishioka M, Kiyota E, Kasai K, Kato T, Iwamoto K
  • Organizer: The 41st Annual Meeting of the Japan Neuroscience Society,
• [Presentation] Eye movement abnormalities and their association with cognitive impairments in schizophrenia. (2018)
  • Author(s): Morita K, Miura K, Fujimoto M, Yamamori H, Yasuda Y, Kudo N, Azechi H, Okada N, Koshiyama D, Kawakami S, Morita S, Ikeda M, Kasai K, Hashimoto R
  • Organizer: The 41st Annual Meeting of the Japan Neuroscience Society,
• [Presentation] Resting-state functional connectivity MRI classification of major depressive disorder in multi-site data. (2018)
  • Author(s): Takamura T, Nakamura T, Yoshinaga K, Ogata Y, Ozaki N, Kasai K, Hashimoto R, Hanakawa T
  • Organizer: The 41st Annual Meeting of the Japan Neuroscience Society,
• [Presentation] Localization and characteristics of auditory steady-state response (ASSR) in the human electrocorticogram (ECoG). (2018)
  • Author(s): Tada M, Kirihara K, Ishishita Y, Kunii N, Shimada S, Ibayashi K, Saito N, Uka T, Kasai K
  • Organizer: The 41st Annual Meeting of the Japan Neuroscience Society,
• [Presentation] nteractive effects of OXTR and GAD1 on envy-associated behaviors and neural responses. (2018)
  • Author(s): Tanaka T, Nishimura F, Kakiuchi C, Kasai K, Kimura M, Haruno M
  • Organizer: The 41st Annual Meeting of the Japan Neuroscience Society,
• [Presentation] Involvement of microRNAs in first-episode psychosis. (2018)
  • Author(s): Zhao Z, Jinde S, Koike S,Yoshikawa A, Satomura Y, Bundo M, Iwamoto K, Kakiuchi C, Kasai K
  • Organizer: The 41st Annual Meeting of the Japan Neuroscience Society,
• [Presentation] 統合失調症患者に対する臺式簡易客観的精神指標（UBOM）の有用性についての検討 (2018)
  • Author(s): 澤田欣吾、榊原英輔、金原明子、小池春菜、藤枝由美子、管心、宮本有紀、福田正人、笠井清登
  • Organizer: 第114回日本精神神経学会学術総会
• [Presentation] 思春期・AYA世代支援の科学． (2018)
  • Author(s): 笠井清登
  • Organizer: 日本小児科学会・第13回思春期医学臨床講習会
  • Invited
• [Presentation] 統合失調症はどこまで治るか 「リカバリーの視点から」 (2018)
  • Author(s): 金原明子、熊倉陽介、笠井清登
  • Organizer: 第13回日本統合失調症学会
• [Presentation] Parental corporal punishment and later bullying: a community cohort study in early adolescence (2018)
  • Author(s): Fujikawa S, Ando S, Nishida A, Patton G, Hasegawa M, Kasai K
  • Organizer: The World Psychiatric Association’s Thematic Congress
  • Int'l Joint Research
• [Presentation] リカバリーをどのように共同創造できるのか ー主体価値の視点から How can we co-product personal recovery? From the viewpoint of personalized value シンポジウム 28（ S28-3）統合失調症のリカバリーガイドライン―当事者との coproduction（共同創造） (2017)
  • Author(s): 笠井清登・金原明子・熊倉陽介
  • Organizer: 第113回 日本精神神経学会学術総会
  • Invited
• [Presentation] 乳幼児期の発達指標と10歳時夜尿との関連 地域住民代表調査 Tokyo Early Adolescent Survey：T-EAS より (2017)
  • Author(s): 金田渉・藤川慎也・鳥山理恵・遠藤香織・森本裕子・小池進介・山崎修道・安藤俊太郎・西田淳志・長谷川眞理子・笠井清登
  • Organizer: 平成29年度 国際思春期科学ワークショップ
• [Presentation] Development of a framework of recovery for mental health service users in Japan (2017)
  • Author(s): Kanehara A, Kumakura Y, Kanata S, Fujieda Y, Koike H, Morita K, Yamaguchi S, Miyamoto Y, Nochi M, Fukuda M, Kasai K
  • Organizer: 6th BESETO
  • Int'l Joint Research
• [Presentation] Development of a framework of recovery for mental health service users in Japan (2017)
  • Author(s): Kanehara A, Kumakura Y, Kanata S, Fujieda Y, Koike H, Morita K, Yamaguchi S, Miyamoto Y, Nochi M, Fukuda M, Kasai K.
  • Organizer: 6th European Conference on Schizophrenia Research
  • Int'l Joint Research
• [Presentation] Development of a question prompt sheet for schizophrenia: dissemination strategies to raise awareness of shared decision making (SDM) in Japan. (2017)
  • Author(s): Kumakura Y, Kanehara A, Kanata S, Natsukari I, Kondo S, Ichihashi K, Suga M, Miyamoto Y, Ikebuchi E, Fukuda M, Kasai K:
  • Organizer: 6th European Conference on Schizophrenia Research
  • Int'l Joint Research
• [Presentation] Slapping as a parental disciplinary practice, warm parenting and bullying involvement in early adolescence: a longitudinal cohort study (2017)
  • Author(s): Fujikawa S, Ando S, Nishida A, Usami S, Koike S, Yamasaki S, Morimoto Y, Toriyama R, Kanata S, Sugimoto N, Sasaki T, Furukawa T, Hasegawa M, Kasai K
  • Organizer: The 16th Congress of the International Federation of Psychiatric Epidemiology
  • Int'l Joint Research
• [Presentation] The Tokyo Teen Cohort study: an adolescent cohort study with life course approach (2017)
  • Author(s): Ando S
  • Organizer: The 21st International Epidemiological Association World Congress of Epidemiology
  • Int'l Joint Research
• [Presentation] Tokyo Teen Cohort Study (2017)
  • Author(s): Ando S, Nishida A
  • Organizer: The 16th Congress of the International Federation of Psychiatric Epidemiology
  • Int'l Joint Research
• [Presentation] ピアスタッフ導入に向けての取り組み：A病院デイケアでのニーズ調査 (2017)
  • Author(s): 藤枝由美子、石橋綾、矢島明佳、清水希実子、管心、金原明子、石浦朋子、宮本有紀、近藤伸介、笠井清登
  • Organizer: 第12回日本統合失調症学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
• [Presentation] 「こころのリスク外来」メール受診相談におけるPRIME-Jスクリーニングの活用 (2017)
  • Author(s): 土屋麻衣子、谷元子、金原明子、太田和佐、小池進介、笠井清登
  • Organizer: 第12回日本統合失調症学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
• [Presentation] テキストマイニング分析を用いた精神科医療機関への支援要請過程に関する調査 (2017)
  • Author(s): 太田和佐、谷元子、土屋麻衣子、金原明子、多田真理子、管心、小池進介、笠井清登
  • Organizer: 第12回日本統合失調症学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
• [Presentation] A病院におけるメタ認知訓練法の効果の検討 (2017)
  • Author(s): 江口聡、管心、藤枝由美子、夏堀龍暢、山崎修道、笠井清登
  • Organizer: 第12回日本統合失調症学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
• [Presentation] 東京大学医学部附属病院における精神障害者試験的雇用の実践報告 (2017)
  • Author(s): 清水希実子、塩原裕理、藤枝由美子、飯田美恵、金原明子、管心、芳賀信彦、笠井清登
  • Organizer: 第12回日本統合失調症学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
• [Presentation] リカバリーを支援するプログラムについて：英国に置けるリカバリーカレッジ運営の実態から (2017)
  • Author(s): 坂井隆太郎、松本衣美、宮本有紀、小川亮、熊倉陽介、森田康子、千葉理恵、西大輔、山口創生、島津明人、近藤伸介、笠井清登
  • Organizer: 第12回日本統合失調症学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
• [Presentation] 英国リカバリーカレッジの効果について：文献レビュー (2017)
  • Author(s): 松本衣美、坂井隆太郎、宮本有紀、小川亮、熊倉陽介、森田康子、千葉理恵、西大輔、山口創生、島津明人、近藤伸介、笠井清登
  • Organizer: 第12回日本統合失調症学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
• [Presentation] 主体的参加によるリカバリー促進実践：英国リカバリーカレッジの提供する講座内容の分析 (2017)
  • Author(s): 宮本有紀、小川亮、坂井隆太郎、松本衣美、山田理絵、熊倉陽介、森田康子、千葉理恵、山口創生、西大輔、島津明人、近藤伸介、笠井清登
  • Organizer: 第12回日本統合失調症学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
• [Presentation] 精神保健サービスおよびサービスに関わる人のリカバリー志向性に関連する評価尺度：文献レビュー (2017)
  • Author(s): 千葉理恵、宮本有紀、山口創生、西大輔、島津明人、近藤伸介、笠井清登
  • Organizer: 第12回日本統合失調症学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
• [Presentation] 統合失調症患者を対象に脳磁計を用いた単一課題中のduration/frequency MMNの測定 (2017)
  • Author(s): 管心、西村幸香、川久保友紀、湯本真人、笠井清登
  • Organizer: 第12回日本統合失調症学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
• [Presentation] 精神病性障害の早期段階に置けるミスマッチ陰性電位の縦断研究 (2017)
  • Author(s): 越山太輔、切原賢治、多田真理子、永井達哉、荒木剛、笠井清登
  • Organizer: 第12回日本統合失調症学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
• [Presentation] 母体の妊娠早期糖尿病罹患と10歳児の精神病症状体験・抑うつの縦断的関連 (2017)
  • Author(s): 山崎修道、安藤俊太郎、小池進介、藤川慎也、金田渉、遠藤香織、森本裕子、宇佐美慧、長谷川眞理子、笠井清登、西田淳志
  • Organizer: 第12回日本統合失調症学会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
• [Presentation] 「新学術領域研究：思春期主体価値」紹介 (2016)
  • Author(s): 笠井清登
  • Organizer: 次世代脳プロジェクト：冬のシンポジウム
  • Place of Presentation: 学術総合センター（東京都千代田区）
• [Presentation] 統合失調症の病態解明へのアプローチ (2016)
  • Author(s): 笠井清登
  • Organizer: 第49回精神神経系薬物治療研究報告会
  • Place of Presentation: 千里ライフサイエンスセンター（大阪府豊中市）
  • Invited
• [Presentation] こころの健康教育教材を用いた出前授業の実施：実践報告 (2016)
  • Author(s): 金原明子、熊倉陽介、金田渉、中野彰夫、笠井清登
  • Organizer: 第20回日本精神保健・予防学会
  • Place of Presentation: 京王プラザホテル（東京都新宿区）
• [Presentation] 思春期メンタルヘルスと援助希求 (2016)
  • Author(s): 安藤俊太郎、西田淳志、宇佐美慧、小池進介、山崎修道、金田渉、藤川慎也、 古川壽亮、長谷川眞理子、笠井清登
  • Organizer: 第20回日本精神保健・予防学会
  • Place of Presentation: 京王プラザホテル（東京都新宿区）
• [Presentation] 思春期主体価値学にもとづく統合失調症の理解と支援 (2016)
  • Author(s): 笠井清登
  • Organizer: 第11回山口県統合失調症研究会
  • Place of Presentation: 山口県
  • Invited
• [Presentation] 双極性障害および統合失調症患者末梢血で認められるSLC6A4プロモーターの高メチル化 (2016)
  • Author(s): 池亀天平、文東美紀、菅原裕子、小池進介、近藤健治、池田匡志、才田晴美、浅井竜朗、吉川茜、西村文親、河村代志也、垣内千尋、佐々木司、石郷岡純、岩田仲生、加藤忠史、笠井清登、岩本和也
  • Organizer: 第38回日本生物学的精神医学会
  • Place of Presentation: 福岡国際会議場（福岡県福岡市）
• [Presentation] At-risk mental stateにおける脳回の過形成 (2016)
  • Author(s): 笹林大樹、高柳陽一郎、小池進介、山末英典、片桐直之、佐久間篤、中村美保子、高橋努、古市厚志、木戸幹雄、西川祐美子、松本和紀、水野雅文、笠井清登、鈴木道雄
  • Organizer: 第38回日本生物学的精神医学会
  • Place of Presentation: 福岡国際会議場（福岡県福岡市）
• [Presentation] 統合失調症と双極性障害におけるエピゲノム要因の共通性と特異性についての検討 (2016)
  • Author(s): 菅原裕子、文東美紀、池亀天平、近藤健治、池田匡志、岩田仲生、石郷岡純、笠井清登、加藤忠史、岩本和也
  • Organizer: 第38回日本生物学的精神医学会
  • Place of Presentation: 福岡国際会議場（福岡県福岡市）
• [Book] 別冊医学のあゆみ・統合失調症UPDATE:脳・生活・人生の統合的理解にもとづく価値医学の最前線 (2018)
  • Author(s): 笠井清登、宮本有紀、福田正人
  • Total Pages: 141
  • Publisher: 医歯薬出版
• [Book] 精神科研修ノート第二版 (2016)
  • Author(s): 笠井清登、村井俊哉、三村將、岡本泰昌、近藤伸介、大島紀人（編）
  • Total Pages: 640
  • Publisher: 診断と治療社
• [Remarks] 脳・生活・人生の統合的理解にもとづく思春期からの主体価値発展学
  • URL: http://value.umin.jp/index.html
• [Remarks] 東京ティーンコホート
  • URL: http://ttcp.umin.jp/
• [Remarks] 脳・生活・人生の統合的理解にもとづく思春期からの主体価値発展学ホームページ
  • URL: http://value.umin.jp/index.html
• [Remarks] 東京ティーンコホートホームページ
  • URL: http://ttcp.umin.jp/
• [Funded Workshop] 国際思春期科学ワークショップ・特別講演 (2019)
• [Funded Workshop] 国際思春期科学ワークショップ・特別講演 (2018)
• [Funded Workshop] 国際思春期科学ワークショップ・特別講演 (2017)
• [Funded Workshop] 国際思春期科学ワークショップ・特別講演 (2016)
  • Place of Presentation: 東京大学 伊藤国際学術研究センター
  • Year and Date: 2016-11-01