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Building an international data-sharing platform towards integrated understanding of the "individuality" within the brain system

International Activities Supporting Group

Project AreaIntegrative research toward elucidation of generative brain systems for individuality
Project/Area Number 16K21734
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeMulti-year Fund
Review Section Complex systems
Research InstitutionTohoku University

Principal Investigator

OSUMI Noriko  東北大学, 医学系研究科, 教授 (00220343)

Co-Investigator(Kenkyū-buntansha) 保前 文高  東京都立大学, 人文科学研究科, 教授 (20533417)
若林 明雄  千葉大学, 大学院人文科学研究院, 名誉教授 (30175062)
中島 欽一  九州大学, 医学研究院, 教授 (80302892)
星野 幹雄  国立研究開発法人国立精神・神経医療研究センター, 神経研究所 病態生化学研究部, 部長 (70301273)
今吉 格  京都大学, 生命科学研究科, 教授 (60543296)
郷 康広  大学共同利用機関法人自然科学研究機構(新分野創成センター、アストロバイオロジーセンター、生命創成探究, 生命創成探究センター, 特任准教授 (50377123)
冨永 貴志  徳島文理大学, 神経科学研究所, 教授 (20344046)
駒木 文保  東京大学, 大学院情報理工学系研究科, 教授 (70242039)
柴田 智広  九州工業大学, 大学院生命体工学研究科, 教授 (40359873)
Project Period (FY) 2016-06-30 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥65,650,000 (Direct Cost: ¥50,500,000、Indirect Cost: ¥15,150,000)
Fiscal Year 2020: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Fiscal Year 2019: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Fiscal Year 2018: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Fiscal Year 2017: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Fiscal Year 2016: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Keywords「個性」 / データシェアリング / オープンサイエンス / 融合研究 / 学際研究 / 脳科学 / 基盤 / 社会脳科学 / 脳計測科学 / 脳科学 基盤 / 社会脳科学 脳計測科学 / 基盤・社会脳科学 / 個性 / 神経基盤
Outline of Final Research Achievements

Although the commonality of human mental functions has been clarified to a great extent through collaboration with related neuroscientific research, the neurobiological basis of individual differences, or "individuality," has not been fully elucidated. In this research project, researchers from the humanities and social sciences, biology, and science and engineering have come together to conduct interdisciplinary research aimed at a scientific understanding of "individuality". As international activities, in addition to sending young researchers abroad and inviting prominent foreign researchers, an international data-sharing platform based on various behavioral data including ultrasonic vocalizations of rodents was established.

Academic Significance and Societal Importance of the Research Achievements

多様なステークホルダーが研究に参画しうるSociety 5.0の推進において、データシェアリングはオープンサイエンスの基本となるものである。本新学術領域により構築したプラットフォームがプロジェクト終了後も何らかの形で維持されることにより、より大きなヴァーチャルな「知の集合体」が構築され、国際的社会に大きな貢献をもたらすことが期待される。

Report

(7 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (169 results)

All 2022 2021 2020 2018 2017 2016 Other

All Int'l Joint Research (9 results) Journal Article (81 results) (of which Int'l Joint Research: 26 results,  Peer Reviewed: 81 results,  Open Access: 63 results,  Acknowledgement Compliant: 2 results) Presentation (67 results) (of which Int'l Joint Research: 51 results,  Invited: 31 results) Book (4 results) Remarks (8 results)

  • [Int'l Joint Research] パスツール研究所(フランス)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] UCSD(米国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] チェラロンコン大学(タイ)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] チェラロンコーン大学(タイ)

    • Related Report
      2020 Research-status Report
  • [Int'l Joint Research] IIIT-Delhi(インド)

    • Related Report
      2020 Research-status Report
  • [Int'l Joint Research] エディンバラ大学(英国)

    • Related Report
      2020 Research-status Report
  • [Int'l Joint Research] トロント・マウントサイナイ病院/フレフェルドタネンバウム研究所/トロント大学(カナダ)

    • Related Report
      2020 Research-status Report
  • [Int'l Joint Research] ウッズホール海洋生物学研究所(米国)

    • Related Report
      2020 Research-status Report
  • [Int'l Joint Research]

    • Related Report
      2020 Research-status Report
  • [Journal Article] Dysregulation of DPYSL2 expression by mTOR signaling in schizophrenia: Multi-level study of postmortem brain2022

    • Author(s)
      Izumi Ryuta、Hino Mizuki、Nagaoka Atsuko、Shishido Risa、Kakita Akiyoshi、Hoshino Mikio、Kunii Yasuto、Yabe Hirooki
    • Journal Title

      Neuroscience Research

      Volume: 175 Pages: 73-81

    • DOI

      10.1016/j.neures.2021.09.004

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Unique Lewy pathology in myotonic dystrophy type 12022

    • Author(s)
      Sano Terunori、Kawazoe Tomoya、Shioya Ayako、Mori‐Yoshimura Madoka、Oya Yasushi、Maruo Kazushi、Nishino Ichizo、Hoshino Mikio、Murayama Shigeo、Saito Yuko
    • Journal Title

      Neuropathology

      Volume: - Issue: 2 Pages: 104-116

    • DOI

      10.1111/neup.12790

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Transit Amplifying Progenitors in the Cerebellum: Similarities to and Differences from Transit Amplifying Cells in Other Brain Regions and between Species2022

    • Author(s)
      Miyashita Satoshi、Hoshino Mikio
    • Journal Title

      Cells

      Volume: 11 Issue: 4 Pages: 726-726

    • DOI

      10.3390/cells11040726

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Oscillator decomposition of infant fNIRS data (accepted)2022

    • Author(s)
      Takeru Matsuda,Fumitaka Homae,Gentaro Taga and Fumiyasu Komaki
    • Journal Title

      PLOS Computational Biology

      Volume: -

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Individual variability in the nonlinear development of the corpus callosum during infancy and2022

    • Author(s)
      Tsuzuki, D., Taga, G., Watanabe, H., Homae, F.
    • Journal Title

      Brain Structure and Function

      Volume: -

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] AUTS2 Gene: Keys to Understanding the Pathogenesis of Neurodevelopmental Disorders2021

    • Author(s)
      Hori Kei、Shimaoka Kazumi、Hoshino Mikio
    • Journal Title

      Cells

      Volume: 11 Issue: 1 Pages: 11-11

    • DOI

      10.3390/cells11010011

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Membrane Potential Imaging with Voltage-sensitive Dye (VSD) for Long-term Recording2021

    • Author(s)
      TOMINAGA Takashi、KAJIWARA Riichi、TOMINAGA Yoko
    • Journal Title

      Seibutsu Butsuri

      Volume: 61 Issue: 6 Pages: 404-408

    • DOI

      10.2142/biophys.61.404

    • NAID

      130008120222

    • ISSN
      0582-4052, 1347-4219
    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Functional Aqp1 Gene Product Localizes on The Contractile Vacuole Complex in Paramecium multimicronucleatum2021

    • Author(s)
      Masaki Ishida, Manabu Hori, Yui Ooba, Masako Kinoshita, Tsuyoshi Matsutani, Musumi Naito, Taeko Hagimoto, Kuniko Miyazaki, Sou Ueda, Ken Miura, Takashi Tominaga
    • Journal Title

      Journal of Eukaryotic Microbiology

      Volume: - Issue: 3 Pages: 1-11

    • DOI

      10.1111/jeu.12843

    • Related Report
      2021 Annual Research Report 2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Growth factors with valproic acid restore injury-impaired hearing by promoting neuronal regeneration2021

    • Author(s)
      Wakizono Takahiro、Nakashima Hideyuki、Yasui Tetsuro、Noda Teppei、Aoyagi Kei、Okada Kanako、Yamada Yasuhiro、Nakagawa Takashi、Nakashima Kinichi
    • Journal Title

      JCI Insight

      Volume: 6 Issue: 22

    • DOI

      10.1172/jci.insight.139171

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling2021

    • Author(s)
      Nakashima Hideyuki、Tsujimura Keita、Irie Koichiro、Imamura Takuya、Trujillo Cleber A.、Ishizu Masataka、Uesaka Masahiro、Pan Miao、Noguchi Hirofumi、Okada Kanako、Aoyagi Kei、Andoh-Noda Tomoko、Okano Hideyuki、Muotri Alysson R.、Nakashima Kinichi
    • Journal Title

      Cell Reports

      Volume: 35 Issue: 7 Pages: 109124-109124

    • DOI

      10.1016/j.celrep.2021.109124

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Regulation of Adult Mammalian Neural Stem Cells and Neurogenesis by Cell Extrinsic and Intrinsic Factors2021

    • Author(s)
      Matsubara Shuzo、Matsuda Taito、Nakashima Kinichi
    • Journal Title

      Cells

      Volume: 10 Issue: 5 Pages: 1145-1145

    • DOI

      10.3390/cells10051145

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Potential involvement of DSCAML1 mutations in neurodevelopmental disorders2021

    • Author(s)
      Ogata S, Hashizume K, Hayase Y, Kanno Y, Hori K, Balan S, Yoshikawa T, Takahashi H, Taya S, Hoshino M
    • Journal Title

      Genes Cells

      Volume: (3) Issue: 3 Pages: 136-151

    • DOI

      10.1111/gtc.12831

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Notch Signaling between Cerebellar Granule Cell Progenitors2021

    • Author(s)
      Adachi Toma、Miyashita Satoshi、Yamashita Mariko、Shimoda Mana、Okonechnikov Konstantin、Chavez Lukas、Kool Marcel、Pfister Stefan M.、Inoue Takafumi、Kawauchi Daisuke、Hoshino Mikio
    • Journal Title

      eneuro

      Volume: 8 Issue: 3 Pages: 0468-20

    • DOI

      10.1523/eneuro.0468-20.2021

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cross-species genomics reveals oncogenic dependencies in ZFTA/C11orf95 fusion-positive supratentorial ependymomas2021

    • Author(s)
      Zheng Tuyu、Ghasemi David R.、Okonechnikov Konstantin、、、Adachi Toma、、、Kawauchi Daisuke、Pajtler Kristian W.
    • Journal Title

      Cancer Discovery

      Volume: 0963 Issue: 9 Pages: 2230-2247

    • DOI

      10.1158/2159-8290.cd-20-0963

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] An Optimized Preparation Method for Long ssDNA Donors to Facilitate Quick Knock-In Mouse Generation2021

    • Author(s)
      Inoue Yukiko U.、Morimoto Yuki、Yamada Mayumi、Kaneko Ryosuke、Shimaoka Kazumi、Oki Shinji、Hotta Mayuko、Asami Junko、Koike Eriko、Hori Kei、Hoshino Mikio、Imayoshi Itaru、Inoue Takayoshi
    • Journal Title

      Cells

      Volume: 10 Issue: 5 Pages: 1076-1076

    • DOI

      10.3390/cells10051076

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Shrinkage priors for single-spiked covariance models2021

    • Author(s)
      Okudo Michiko、Komaki Fumiyasu
    • Journal Title

      Statistics & Probability Letters

      Volume: 176 Pages: 109127-109127

    • DOI

      10.1016/j.spl.2021.109127

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Shrinkage Priors on Complex-Valued Circular- Symmetric Autoregressive Processes2021

    • Author(s)
      Oda Hidemasa、Komaki Fumiyasu
    • Journal Title

      IEEE Transactions on Information Theory

      Volume: 67 Issue: 8 Pages: 5318-5333

    • DOI

      10.1109/tit.2021.3079512

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Shrinkage Priors for Nonparametric Bayesian Prediction of Nonhomogeneous Poisson Processes2021

    • Author(s)
      Komaki Fumiyasu
    • Journal Title

      IEEE Transactions on Information Theory

      Volume: 67 Issue: 8 Pages: 5305-5317

    • DOI

      10.1109/tit.2021.3084062

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Statistical modeling for temporal dominance of sensations data incorporating individual characteristics of panelists: an application to data of milk chocolate2021

    • Author(s)
      Sumito Kurata,Reiko Kuroda,Fumiyasu Komaki
    • Journal Title

      Journal of Food Science and Technology

      Volume: - Issue: 6 Pages: 2420-2428

    • DOI

      10.1007/s13197-021-05260-9

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Detection of <scp>REST</scp> expression in the testis using epitope‐tag knock‐in mice generated by genome editing2021

    • Author(s)
      Kimura Ryuichi、U. Inoue Yukiko、Kikkawa Takako、Tatehana Misako、Morimoto Yuki、Inada Hitoshi、Oki Shinya、Inoue Takayoshi、Osumi Noriko
    • Journal Title

      Developmental Dynamics

      Volume: 251 Issue: 3 Pages: 525-535

    • DOI

      10.1002/dvdy.417

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Autism-Related Transcription Factors Underlying the Sex-Specific Effects of Prenatal Bisphenol A Exposure on Transcriptome-Interactome Profiles in the Offspring Prefrontal Cortex2021

    • Author(s)
      Kanlayaprasit Songphon、Thongkorn Surangrat、Panjabud Pawinee、Jindatip Depicha、Hu Valerie W.、Kikkawa Takako、Osumi Noriko、Sarachana Tewarit
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 24 Pages: 13201-13201

    • DOI

      10.3390/ijms222413201

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Perirhinal cortex area 35 controls the functional link between the perirhinal and entorhinal‐hippocampal circuitry.2021

    • Author(s)
      Kajiwara R, Tominaga T
    • Journal Title

      Bioessays

      Volume: 43 Issue: 3 Pages: 2000084-2000084

    • DOI

      10.1002/bies.202000084

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Narcissism in independent and interdependent cultures.2021

    • Author(s)
      Jauk,E., Breyer, D., Kanske, P., & Wakabayashi, A.
    • Journal Title

      Personality and Individual Differences

      Volume: 177 Pages: 110716-110716

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Sex differences in the effects of prenatal bisphenol A exposure on autism-related genes and their relationships with the hippocampus functions2021

    • Author(s)
      Thongkorn Surangrat、Kanlayaprasit Songphon、Panjabud Pawinee、Saeliw Thanit、Jantheang Thanawin、Kasitipradit Kasidit、Sarobol Suthathip、Jindatip Depicha、Hu Valerie W.、Tencomnao Tewin、Kikkawa Takako、Sato Tatsuya、Osumi Noriko、Sarachana Tewarit
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1

    • DOI

      10.1038/s41598-020-80390-2

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Paternal age affects offspring via an epigenetic mechanism involving REST/NRSF.2021

    • Author(s)
      Yoshizaki Kaichi, Kimura Ryuichi, Kobayashi Hisato, Oki Shinya, Kikkawa Takako, Mai Lingling, Koike Kohei, Mochizumi Kentaro, Inada Hitoshi, Matsui Yasuhisa, Kono Tomohiro, Osumi Noriko
    • Journal Title

      EMBO Reports

      Volume: 22(2) Issue: 2

    • DOI

      10.15252/embr.202051524

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prioritized experience replays on a hippocampal predictive map for learning2021

    • Author(s)
      Hideyoshi Igata, Yuji Ikegaya , Takuya Sasaki
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 118(1) Issue: 1

    • DOI

      10.1073/pnas.2011266118

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prefrontal synaptic activation during hippocampal memory reactivation2021

    • Author(s)
      Yuya Nishimura , Yuji Ikegaya , Takuya Sasaki
    • Journal Title

      Cell Reports

      Volume: 34(12) Issue: 12 Pages: 108885-108885

    • DOI

      10.1016/j.celrep.2021.108885

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Deconvolution of calcium imaging data using marked point processes2020

    • Author(s)
      Ryohei Shibue,Fumiyasu Komaki
    • Journal Title

      PLOS Computational Biology

      Volume: 16(3) Issue: 3 Pages: e1007650-e1007650

    • DOI

      10.1371/journal.pcbi.1007650

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Birefringence Changes of Dendrites in Mouse Hippocampal Slices Revealed with Polarizing Microscopy.2020

    • Author(s)
      Maki Koike-Tani M, Takashi Tominaga, Rudolf Oldenbourg, Tomomi Tani.
    • Journal Title

      Biophys J.

      Volume: - Issue: 10 Pages: 2366-2384

    • DOI

      10.1016/j.bpj.2020.03.016

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Optogenetic Manipulation of Postsynaptic cAMP Using a Novel Transgenic Mouse Line Enables Synaptic Plasticity and Enhances Depolarization Following Tetanic Stimulation in the Hippocampal Dentate Gyrus2020

    • Author(s)
      Luyben, T., Rai, J., Li, H., Georgiou, J., Avila, A., Zhen, M., Collingridge, G., Tominaga, T., Okamoto, K.
    • Journal Title

      Frontiers in Neural Circuits

      Volume: 14 Pages: 24-24

    • DOI

      10.3389/fncir.2020.00024

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] AUTS2 regulation of synapses for proper synaptic inputs and social communication.2020

    • Author(s)
      Hori Kei、Yamashiro Kunihiko、Nagai Taku、... Yamada Mitsuhiko、Yamada Kiyofumi、Hoshino Mikio
    • Journal Title

      iScience

      Volume: ー Issue: 6 Pages: 101183-101183

    • DOI

      10.1016/j.isci.2020.101183

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Roles of Adenylate Cyclases in Ciliary Responses of Paramecium to Mechanical Stimulation2020

    • Author(s)
      Mutsumi Kawano, Takashi Tominaga, Masaki Ishida, Manabu Hori
    • Journal Title

      Journal of Eukaryotic Microbiology

      Volume: 67 Issue: 5 Pages: 532-540

    • DOI

      10.1111/jeu.12800

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility.2020

    • Author(s)
      Hayase Y, Amano S, Hashizume K, Tominaga T, Miyamoto H, Kanno Y, Ueno-Inoue Y, Inoue T, Yamada M, Ogata S, Balan S, Hayashi K, Miura Y, Tokudome K, Ohno Y, Nishijo T, Momiyama T, Yanagawa Y, Takizawa A, Mashimo T, Serikawa T, Sekine A, Nakagawa E, Takeshita E, Yoshikawa T, Waga C, Inoue K, Goto YI, Nabeshima Y, et al.
    • Journal Title

      Acta Neuropathol Commun.

      Volume: 8 Issue: 1 Pages: 206-206

    • DOI

      10.1186/s40478-020-01082-6

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Optimization of light-inducible Gal4/UAS gene expression system in mammalian cells2020

    • Author(s)
      Yamada M., Nagasaki C. S., Suzuki Y., Imayoshi I.
    • Journal Title

      iScience

      Volume: 23 Issue: 9 Pages: 101506-101506

    • DOI

      10.1016/j.isci.2020.101506

    • NAID

      120006884197

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Light-induced silencing of neural activity in Rosa26 knock-in and BAC transgenic mice conditionally expressing the microbial halorhodopsin eNpHR3.2020

    • Author(s)
      Imayoshi I, Tabuchi S, Matsumoto M, Kitano S, Miyachi H, Kageyama R, Yamanaka A
    • Journal Title

      Sci Rep

      Volume: 10(1) Issue: 1 Pages: 3191-3191

    • DOI

      10.1038/s41598-020-59984-3

    • NAID

      120006878490

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors2020

    • Author(s)
      Seymour Philip Allan、Collin Caitlin Alexis、Egeskov-Madsen Anuska la Rosa、Jorgensen Mette Christine、Shimojo Hiromi、Imayoshi Itaru、de Lichtenberg Kristian Honnens、Kopan Raphael、Kageyama Ryoichiro、Serup Palle
    • Journal Title

      Developmental Cell

      Volume: 52 Issue: 6 Pages: 731-747

    • DOI

      10.1016/j.devcel.2020.01.015

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cholecystokinin-expressing Interneurons of the Medial Prefrontal Cortex Mediate Working Memory Retrieval.2020

    • Author(s)
      Nguyen, R., Venkatesan, S., Binko, M., Yoon Bang, J., Cajanding, J.D., Briggs, C., Sargin, D., Imayoshi, I., Lambe, E.K. and Chul Kim, J.
    • Journal Title

      J Neurosci.

      Volume: 40 Issue: 11 Pages: 2314-2331

    • DOI

      10.1523/jneurosci.1919-19.2020

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression.2020

    • Author(s)
      Nakagawa T, Hattori S, Nobuta R, Kimura R, Nakagawa M, Matsumoto M, Nagasawa Y, Funayama R, Miyakawa T, Inada T, Osumi N, Nakayama KI, Nakayama K.
    • Journal Title

      iScience

      Volume: 23 Issue: 4 Pages: 101030-101030

    • DOI

      10.1016/j.isci.2020.101030

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comprehensive histochemical profiles of histone modification in male germline cells during meiosis and spermiogenesis: Comparison of young and aged testes in mice2020

    • Author(s)
      Tatehana M, Kimura R, Mochizuki K, Inada H, Osumi N
    • Journal Title

      PLoS One

      Volume: eCollection 2020 Issue: 4 Pages: e0230930-e0230930

    • DOI

      10.1371/journal.pone.0230930

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis2020

    • Author(s)
      Casingal Cristine R.、Kikkawa Takako、Inada Hitoshi、Sasaki Yukio、Osumi Noriko
    • Journal Title

      Molecular Brain

      Volume: 13 Issue: 1 Pages: 1-13

    • DOI

      10.1186/s13041-020-00706-1

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Light-mediated Control of Gene Expression in Mammalian Cells.2020

    • Author(s)
      Yamada M, Nagasaki C. S, Ozawa T, Imayoshi I.
    • Journal Title

      Neuroscience Research

      Volume: 152 Pages: 66-77

    • DOI

      10.1016/j.neures.2019.12.018

    • NAID

      120006888020

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 欠如モデル・一方向コミュニケーション・双方向コミュニケーションーー科学技術コミュニケーションにおける中核概念の再配置2020

    • Author(s)
      内田麻理香,原塑
    • Journal Title

      科学技術社会論研究

      Volume: 18 Pages: 208-220

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] DSCAM regulates delamination of neurons in the developing midbrain2020

    • Author(s)
      Arimura Nariko、Okada Mako、Taya Shinichiro、Dewa Ken-ichi、Tsuzuki Akiko、Uetake Hirotomo、Miyashita Satoshi、Hashizume Koichi、Shimaoka Kazumi、Egusa Saki、Nishioka Tomoki、Yanagawa Yuchio、Yamakawa Kazuhiro、Inoue Yukiko U.、Inoue Takayoshi、Kaibuchi Kozo、Hoshino Mikio
    • Journal Title

      Science Advances

      Volume: 6 Issue: 36 Pages: 1693-1693

    • DOI

      10.1126/sciadv.aba1693

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Explicit performance in girls and implicit processing in boys: A simultaneous fNIRS-ERP study on second language syntactic learning in young adolescents.2018

    • Author(s)
      Sugiura L, Hata M, Matsuba Kurita H, Uga M, Tsuzuki D, Dan I, Hagiwara H and Homae
    • Journal Title

      Frontiers in Human Neuroscience 1

      Volume: 12 Pages: 1-12

    • DOI

      10.3389/fnhum.2018.00062

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Therapeutic time window of anti-high mobility group box-1 antibody administration in mouse model of spinal cord injury.2018

    • Author(s)
      Nakashima H, Tsujimura K, Irie K, Ishizu M, Pan M, Kameda T, Nakashima K:
    • Journal Title

      Neurosci Res

      Volume: - Pages: 63-70

    • DOI

      10.1016/j.neures.2018.03.004

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Ectopic neurogenesis induced by prenatal antiepileptic drug exposure augments seizure susceptibility in adult mice.2018

    • Author(s)
      Sakai A, Matsuda T, Doi H, Nagaishi Y, Kato K, Nakashima K
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: - Issue: 16 Pages: 4270-4275

    • DOI

      10.1073/pnas.1716479115

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Prior Treatment with Anti-High Mobility Group Box-1 Antibody Boosts Human Neural Stem Cell Transplantation-Mediated Functional Recovery After Spinal Cord Injury.2018

    • Author(s)
      Uezono N, Zhu Y, Y, Matsuda T,Nakajo M, Abematsu M, Setoguchi T, Mori S, Takahashi HK, Komiya S, Nishibori M, Nakashima K:
    • Journal Title

      Stem Cells

      Volume: - Issue: 5 Pages: 0-0

    • DOI

      10.1002/stem.2802

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] HMGB2 expression is associated with transition from a quiescent to an activated state of adult neural stem cells.2018

    • Author(s)
      Kimura A, Matsuda T, Sakai A, Murao N, Nakashima K
    • Journal Title

      Dev Dyn

      Volume: 247 Issue: 1 Pages: 229-238

    • DOI

      10.1002/dvdy.24559

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Neural stem cell therapy aiming at better functional recovery after spinal cord injury.2018

    • Author(s)
      Zhu Y, Uezono N, Yasui T, Nakashima K
    • Journal Title

      Dev Dyn

      Volume: 247

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation2018

    • Author(s)
      Owa Tomoo、Taya Shinichiro、Miyashita Satoshi、Yamashita Mariko、Adachi Toma、Yamada Koyo、Yokoyama Miwa、Aida Shogo、Nishioka Tomoki、Inoue Yukiko U.、Goitsuka Ryo、Nakamura Takuro、Inoue Takayoshi、Kaibuchi Kozo、Hoshino Mikio
    • Journal Title

      The Journal of Neuroscience

      Volume: 38 Issue: 5 Pages: 1277-1294

    • DOI

      10.1523/jneurosci.1545-17.2017

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Generation of Pax6-IRES-EGFP knock-in mouse via the cloning-free CRISPR/Cas9 system to reliably visualize neurodevelopmental dynamics2018

    • Author(s)
      Inoue Yukiko U.、Morimoto Yuki、Hoshino Mikio、Inoue Takayoshi
    • Journal Title

      Neuroscience Research

      Volume: in press Pages: 1-7

    • DOI

      10.1016/j.neures.2018.01.007

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Entrainment of the Circadian Clock in Neural Stem Cells by Epidermal Growth Factor is Closely Associated with ERK1/2-mediated Induction of Multiple Clock-related Genes2018

    • Author(s)
      Mogi A, Yomoda R, Kimura S, Tsushima C, Takouda J, Sawauchi M, Maekawa T, Ohta H, Nishino S, Kurita M, Mano N, Osumi N, Moriya T
    • Journal Title

      Neuroscience

      Volume: 379 Pages: 45-66

    • DOI

      10.1016/j.neuroscience.2018.02.045

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] The role of Pax6 in brain development and its impact on pathogenesis of autism spectrum disorder2018

    • Author(s)
      Kikkawa Takako、Casingal Cristine R.、Chun Seung Hee、Shinohara Hiroshi、Hiraoka Kotaro、Osumi Noriko
    • Journal Title

      Brain Research

      Volume: - Pages: 30111-2

    • DOI

      10.1016/j.brainres.2018.02.041

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Adult-born neurons facilitate olfactory bulb pattern separation during task engagement.2018

    • Author(s)
      Li W, Chu MW, Wu A, Suzuki Y, Imayoshi I and Komiyama T
    • Journal Title

      eLife

      Volume: 7

    • DOI

      10.7554/elife.33006

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The effects of actual situations and the facial expressions of another person when experiencing pain on observers&apos; understanding of the pain and sense of unpleasantness2017

    • Author(s)
      河村康佑、若林明雄
    • Journal Title

      The Japanese Journal of Cognitive Psychology

      Volume: 15 Issue: 1 Pages: 13-19

    • DOI

      10.5265/jcogpsy.15.13

    • NAID

      130006251026

    • ISSN
      1348-7264, 2185-0321
    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Synergistic induction of astrocytic differentiation by factors secreted from meninges in the mouse developing brain.2017

    • Author(s)
      Kawamura Y, Katada S, Noguchi H, Yamamoto H, Sanosaka T, Iihara K, Nakashima K
    • Journal Title

      FEBS lett

      Volume: 59 Issue: 22 Pages: 3709-3720

    • DOI

      10.1002/1873-3468.12881

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] DNA Methylome Analysis Identifies Transcription Factor-Based Epigenomic Signatures of Multilineage Competence in Neural Stem/Progenitor Cells.2017

    • Author(s)
      Sanosaka T, Imamura T, Hamazaki N, Chai M, Igarashi K, Ideta-Otsuka M, Miura F, Ito T, Fujii N, Ikeo K, Nakashima K
    • Journal Title

      Cell Rep

      Volume: 20 Issue: 12 Pages: 2992-3003

    • DOI

      10.1016/j.celrep.2017.08.086

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] NEUROD1 instructs neuronal conversion in non-reactive astrocytes.2017

    • Author(s)
      Brulet R, Matsuda T, Zhang L, Miranda C, Giacca M, Kaspar BK, Nakashima K, Hsieh J
    • Journal Title

      Stem Cell Reports

      Volume: 8 Issue: 6 Pages: 1506-1515

    • DOI

      10.1016/j.stemcr.2017.04.013

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Emerging mechanisms underlying astrogenesis in the developing mammalian brain2017

    • Author(s)
      Takouda J, Katada S, Nakashima K
    • Journal Title

      Proceedings of the Japan Academy, Series B

      Volume: 93 Issue: 6 Pages: 386-398

    • DOI

      10.2183/pjab.93.024

    • NAID

      130005696812

    • ISSN
      0386-2208, 1349-2896
    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Hypoxia epigenetically confers astrocytic differentiation potential on human pluripotent cell-derived neural precursor cells.2017

    • Author(s)
      Yasui T, Uezono N, Nakashima H Noguchi H, Matsuda T, Noda-Andoh T, Okano H, Nakashima K:
    • Journal Title

      Stem Cell Reports

      Volume: 8 Issue: 6 Pages: 1743-1756

    • DOI

      10.1016/j.stemcr.2017.05.001

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Dynamics of the cell division orientation of granule cell precursors during cerebellar development.2017

    • Author(s)
      Miyashita S, Adachi T, Yamashita M, Sota T, Hoshino M:
    • Journal Title

      Mech Dev

      Volume: 147 Pages: 1-7

    • DOI

      10.1016/j.mod.2017.06.002

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Pathologic Active mTOR Mutation in Brain Malformation with Intractable Epilepsy Leads to Cell-Autonomous Migration Delay2017

    • Author(s)
      Hanai S, Sukigara S, Dai H, Owa T, Horike SI, Otsuki T, Saito T, Nakagawa E, Ikegaya N, Kaido T, Sato N, Takahashi A, Sugai K, Saito Y, Sasaki M, Hoshino M, Goto YI, Koizumi S, Itoh M
    • Journal Title

      The American Journal of Pathology

      Volume: 187 Issue: 5 Pages: 1177-1185

    • DOI

      10.1016/j.ajpath.2017.01.015

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Neuronal Migration and AUTS2 Syndrome2017

    • Author(s)
      Kei Hori、Mikio Hoshino
    • Journal Title

      Brain Sciences

      Volume: 7 Issue: 5 Pages: 54-54

    • DOI

      10.3390/brainsci7050054

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Organizing activity of Fgf8 on the anterior telencephalon.2017

    • Author(s)
      Sato T, Kikkawa T, Saito T, Itoi K, Osumi N
    • Journal Title

      Dev Growth Differ

      Volume: 59 Issue: 9 Pages: 701-712

    • DOI

      10.1111/dgd.12411

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Early postnatal vocalizations predict sociability and spatial memory in C57BL6/J mice: individual differences in behavioral traits emerge early in development.2017

    • Author(s)
      Yoshizaki Kaichi, Koike Kohei, Kimura Ryuichi, Osumi Noriko
    • Journal Title

      PLoS One

      Volume: - Issue: 11 Pages: e0186798-e0186798

    • DOI

      10.1371/journal.pone.0186798

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Direct estimation of de novo mutation rates in a chimpanzee parent-offspring trio by ultra-deep whole genome sequencing2017

    • Author(s)
      Tatsumoto Shoji、Go Yasuhiro、Fukuta Kentaro、Noguchi Hideki、Hayakawa Takashi、Tomonaga Masaki、Hirai Hirohisa、Matsuzawa Tetsuro、Agata Kiyokazu、Fujiyama Asao
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 13561-13561

    • DOI

      10.1038/s41598-017-13919-7

    • NAID

      120006358802

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Network analysis of exploratory behaviors of mice in a spatial learning and memory task.2017

    • Author(s)
      Suzuki Y and Imayoshi I
    • Journal Title

      PLoS One.

      Volume: 12

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Firing rate estimation using infinite mixture models and its application to neural decoding.2017

    • Author(s)
      Shibue R, Komaki F:
    • Journal Title

      Journal of Neurophysiology

      Volume: 118 Issue: 5 Pages: 2902-2913

    • DOI

      10.1152/jn.00818.2016

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Multivariate time series decomposition into oscillation components.2017

    • Author(s)
      Matsuda T, Komaki F:
    • Journal Title

      Neural Computation

      Volume: 29 Issue: 8 Pages: 2055-2075

    • DOI

      10.1162/neco_a_00981

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Electroporation in the Rodent Embryonic Brain Using Whole Embryo Culture System.2017

    • Author(s)
      Kikkawa T, Takahashi M, Osumi N
    • Journal Title

      Curr Protoc Neurosci.

      Volume: 78 Issue: 1 Pages: 1-16

    • DOI

      10.1002/cpns.21

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] NeuroD1 instructs neuronal conversion 1 in non-reactive astrocytes2017

    • Author(s)
      Brulet R, Matsuda T, Zhang L, Miranda C, Giacca M, Kaspar BK, Nakashima K Hsieh J.
    • Journal Title

      Stem Cell Rep.

      Volume: 印刷中

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Manipulation of Promoter-Associated Noncoding RNAs in Mouse Early Embryos for Controlling Sequence-Specific Epigenetic Status.2017

    • Author(s)
      Hamazaki N, Nakashima K, Imamura T.
    • Journal Title

      Methods Mol Biol

      Volume: 1543 Pages: 271-282

    • DOI

      10.1007/978-1-4939-6716-2_16

    • ISBN
      9781493967148, 9781493967162
    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] A point process modeling approach for investigating the effect of online brain activity on perceptual switching,2017

    • Author(s)
      Matsuda, T., Kitajo, K., Yamaguchi, Y., and Komaki, F.
    • Journal Title

      NeuroImage

      Volume: 152 Pages: 50-59

    • DOI

      10.1016/j.neuroimage.2017.02.068

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Time series decomposition into oscillation components and phase estimation2017

    • Author(s)
      Matsuda, T. and Komaki, F.
    • Journal Title

      Neural Computation

      Volume: 29 Issue: 2 Pages: 332-367

    • DOI

      10.1162/neco_a_00916

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Individual Differences and the Effect of Face Configuration Contexts in the McGurk Effect2017

    • Author(s)
      Ujiie, Y., Asai, Y., Wakabayashi, A.
    • Journal Title

      Experimental Brain Research

      Volume: 印刷中

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Paternal Aging Affects Behavior in Pax6 Mutant Mice: A Gene/Environment Interaction in Understanding Neurodevelopmental Disorders.2016

    • Author(s)
      Yoshizaki K, Furuse, T, Kimura R, Tucci V, Kaneda H, Wakana S and Osumi N
    • Journal Title

      PLoS One

      Volume: 11 Issue: 11 Pages: e0166665-e0166665

    • DOI

      10.1371/journal.pone.0166665

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Mechanisms of DHA transport to the brain and potential therapy to neurodegenerative diseases.2016

    • Author(s)
      Lo Van A, Sakayori N, Hachem M, Belkouch M, Picq M, Lagarde M, Osumi N, Bernoud-Hubac N.
    • Journal Title

      Biochimie

      Volume: 130 Pages: 163-167

    • DOI

      10.1016/j.biochi.2016.07.011

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Maternal Nutritional Imbalance between Linoleic Acid and Alpha-Linolenic Acid Increases Offspring’s Anxious Behavior with a Sex-Dependent Manner in Mice2016

    • Author(s)
      Sakayori, N., Tokuda, H., Yoshizaki, K., Kawashima, H., Innis, SM., Shibata, H. and Osumi, N
    • Journal Title

      The Tohoku Journal of Experimental Medicine

      Volume: 240 Issue: 1 Pages: 31-37

    • DOI

      10.1620/tjem.240.31

    • NAID

      130005406204

    • ISSN
      0040-8727, 1349-3329
    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Single-neuron and genetic correlates of autistic behavior in macaque2016

    • Author(s)
      K. Yoshida, Y. Go, I. Kushima, A. Toyoda, A. Fujiyama, H. Imai, N. Saito, A. Iriki, N. Ozaki, M. Isoda
    • Journal Title

      Science Advances

      Volume: 2 Issue: 9

    • DOI

      10.1126/sciadv.1600558

    • NAID

      120006222007

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Identification of Protein Kinase Substrates by the Kinase-Interacting Substrate Screening (KISS) Approach2016

    • Author(s)
      Amano, M., Nishioka, T., Yura, Y., and Kaibuchi, K.
    • Journal Title

      Curr Protoc Cell Biol

      Volume: 72 Issue: 1 Pages: 14161-141612

    • DOI

      10.1002/cpcb.8

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Brain enhancer activities at the gene-poor 5p14.1 utism-assocaited locus.2016

    • Author(s)
      Inoue YU, Inoue T
    • Journal Title

      Sci Rep.

      Volume: 9 Issue: 1 Pages: 31227-31227

    • DOI

      10.1038/srep31227

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 自閉症感受性遺伝子Auts2はマウス大脳皮質形成において上層神経細胞の産生を制御する2022

    • Author(s)
      嶋岡可純,堀 啓,坂本亜沙美,井上由紀子,郷康 弘,阿部 学,崎村建司,井上高良,星野幹雄
    • Organizer
      第14回CBIR若手シンポジウム
    • Related Report
      2021 Annual Research Report
  • [Presentation] Regulation of cerebellar neural progenitors and cerebellar evolution2021

    • Author(s)
      Mikio Hoshino, Satoshi Miyashita
    • Organizer
      神経科学会, Symposium "Regulation of neural stem cells and new development of brain evolution study"
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Novel function of Down Syndrome Cell Adhesion Molecule in mammalian brain development2021

    • Author(s)
      Mikio Hoshino
    • Organizer
      Fujihara Seminar
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Information geometry of predictive densities and its application to Poisson-based models2021

    • Author(s)
      Fumiyasu Komaki
    • Organizer
      EAC-ISBA2021 (Hybrid)
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 高速超解像から大規模3Dまで、バイオイメージングを遍くカバーする最新顕微鏡技術群2021

    • Author(s)
      今吉 格
    • Organizer
      第44回日本神経科学大会
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Analysis of neural stem cell regulatory mechanisms using optogenetics2021

    • Author(s)
      今吉 格
    • Organizer
      第1回 CJK 国際会議
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Roles of postnatal and adult neurogenesis in brain development and maturation2021

    • Author(s)
      今吉 格
    • Organizer
      The 80th Fujihara Seminar
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] マウス前頭前野の同側,反対側への神経活動伝播の膜電位感受性色素による機能的解剖2021

    • Author(s)
      冨永 貴志、グサイン プージャ、竹歳 麻紀子、冨永 洋子
    • Organizer
      The 44th annual meeting of the Japan neuroscience society/第44回日本神経科学大会CJK第1回国際大会
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 膜電位感受性色素( VSD)イメージングによる in vitro痙攣リスク予測2021

    • Author(s)
      内海 雄一、竹歳 麻紀子、小原 菜夏、三輪 倫子、冨永 洋子、冨永 貴志
    • Organizer
      The 44th annual meeting of the Japan neuroscience society/第44回日本神経科学大会CJK第2回国際大会
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cuprizone短期投与による脳内炎症モデルマウスは統合失調症様行動障害を示す2021

    • Author(s)
      佃 京華、窪田 剛志、千葉 葵、冨永 貴志、岸本 泰司、中島 健太郎
    • Organizer
      The 44th annual meeting of the Japan neuroscience society/第44回日本神経科学大会CJK第3回国際大会
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 抑制性シナプス抑制因子MDGA1のヘミ欠損は海馬 LTPの低下と学習・記憶異常を引き起こすが、サイクロセリンの急性投与により回復する2021

    • Author(s)
      山本 融、尾嶋 大喜、多田 篤史、田之上 優、黒川 直弘、窪田 剛志、高橋 弘雄、岸本 泰司、冨永 貴志
    • Organizer
      The 44th annual meeting of the Japan neuroscience society/第44回日本神経科学大会CJK第4回国際大会
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 電位感受性色素(VSD)による全神経回路活動計測の開発:海馬スライス標本へのビスフェノールA関連物質の急性投与2021

    • Author(s)
      冨永 貴志, 竹歳 麻紀子, 種村 健太郎, 冨永 洋子
    • Organizer
      第48回日本毒性学会学術年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 電位感受性色素(VSD)イメージングによるinvitro痙攣リスク評価法の開発2021

    • Author(s)
      内海 雄一, 竹歳 麻紀子, 小原 菜夏, 三輪 倫子, 冨永 洋子, 冨永 貴志
    • Organizer
      第48回日本毒性学会学術年会 神戸
    • Related Report
      2021 Annual Research Report
  • [Presentation] 期投与脳内炎症モデルマウスは統合失調症様精神行動障害を示す2021

    • Author(s)
      佃 京華, 窪田剛志, 千葉 葵, 冨永 貴志, 岸本 泰司, 中島 健太郎
    • Organizer
      日本生物物理学会 中国四国支部大会(第12回)
    • Related Report
      2021 Annual Research Report
  • [Presentation] Quantitative detection of the effect on neuronal responses in tri-synapses with the acute application of bisphenol-A-related substances on hippocampal slices with voltage-sensitive dye (VSD)2021

    • Author(s)
      Y. TOMINAGA, M. TAKETOSHI, K. TANEMURA, *T. TOMINAGA
    • Organizer
      Society for Neuroscience, Neuroscience 2021
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 精神医学研究に対する動物モデルを用いた基礎研究の貢献How animal models can contribute to psychiatric research?2021

    • Author(s)
      大隅典子
    • Organizer
      第44回日本神経科学大会(CJK国際会議)
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] DOHaDからPOHaDへ:継精子エピ変異の次世代脳発達への影響2021

    • Author(s)
      大隅典子
    • Organizer
      第48回日本毒性学会学術年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 父加齢と次世代のニューロダイバーシティ2021

    • Author(s)
      大隅典子
    • Organizer
      日本発達神経科学会第10回学術集会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 脳の発生発達と機能に必要な神経新生を理解する2021

    • Author(s)
      大隅典子
    • Organizer
      第99回日本生理学会大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] シナプスの可視化とその脳疾患研究への応用2021

    • Author(s)
      大隅典子
    • Organizer
      PNP第43回 日本生物学的精神医学会 第51回 日本神経精神薬理学会 合同年会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] Regulatory mechanism of neural stem cells revealed by optical manipulation of gene expressions2021

    • Author(s)
      今吉 格
    • Organizer
      第11回新潟大学脳研究所共同研究拠点国際シンポジウム
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Transgenerational Epigenetics: A Key to Understand Neurodevelopmental Diseases2021

    • Author(s)
      大隅 典子
    • Organizer
      CINP2021 VIRTUAL WORLD CONGRESS
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Optical membrane potential recordings with voltage-sensitive dye (VSD) enabling recordings of rare and unique neuronal activity patterns2020

    • Author(s)
      Y Tominaga, R Kajiwara, T Tominaga
    • Organizer
      Society for Neuroscience, Global Connectome (Online)
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] VSDイメージングによる神経回路毒性の網羅的評価2020

    • Author(s)
      冨永 貴志, 冨永 洋子
    • Organizer
      第47回日本毒性学会学術年会 (仙台、オンライン)
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] 単回頻回の膜電位感受性色素( VSD)による広視野可視化法 は神経回路の特異な活動や振動現象の発見に役立つ2020

    • Author(s)
      冨永 貴志、梶原 利一、冨永 洋子
    • Organizer
      第43回日本神経科学大会(神戸、オンライン)
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] 発達期および成体期におけるマウス嗅皮質神経回路の膜電位イメージング解析2020

    • Author(s)
      待田 燿子 , 山田 悠太 , 冨永 貴志 , 梶原 利一
    • Organizer
      第43回日本神経科学大会(神戸、オンライン)
    • Related Report
      2020 Research-status Report
  • [Presentation] Imaging analysis of the long-term potentiation of the mouse hippocampal activityマウス海馬の長期増強を膜電位感受色素によるイメージングで観察する2020

    • Author(s)
      冨永 洋子, 竹歳 麻紀子, 冨永 貴志
    • Organizer
      第58回日本生物物理学会(群馬、オンライン)
    • Related Report
      2020 Research-status Report
  • [Presentation] 発生発達期暴露による嗅球神経新生影響~毒性評価としての嗅球利用を探る~2020

    • Author(s)
      今吉 格
    • Organizer
      第47回日本毒性学会学術年会
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Toward understanding and manipulation of neural bases underlying animal behaviors and psychiatric diseases2020

    • Author(s)
      今吉 格
    • Organizer
      第43回日本分子生物学会年会シンポジウム
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 個性を科学するためのチャレンジ2020

    • Author(s)
      大隅 典子
    • Organizer
      NTTニケーション科学基礎研究所オープンハウス
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] 先天異常からDOHaDへ:鍵となる次世代継承エピジェネティ クス2020

    • Author(s)
      大隅 典子
    • Organizer
      先天異常学会
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] 精神医学研究に対する齧歯類を用いた基礎研究の貢献2020

    • Author(s)
      大隅 典子
    • Organizer
      日本精神神経学会総会シンポジウム
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] Transgenerational epigenetics: a possible scenario for the onset of neurodevelopmental diseases2020

    • Author(s)
      大隅 典子
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] Analysis of Autism Susceptibility Candidate 2 (AUTS2) gene during development2018

    • Author(s)
      Hoshino M, Hori K
    • Organizer
      第8回 新潟大学脳研究所共同研究拠点国際シンポジウム
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] The role of AUTS2 in synaptic formation and the cognitive brain functions2018

    • Author(s)
      Hori K, Nagai T, Shan W, Yamada M, Shiraishi R, Sakamoto A, Kanno K, Abe M, Yamada K, Sakimura K, Hoshino M
    • Organizer
      第8回新潟大学脳研究所共同研究拠点国際シンポジウム
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Visualization and humanization of oxytocin receptor expressions in mice; towards the clinical application of oxytocin to autism spectrum disorders2018

    • Author(s)
      Inoue YU, Morimoto Y, Inoue T
    • Organizer
      第9回 武田科学振興財団薬科学シンポジウム Genome Editing Towards Medicinal Applications
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Insights into Rett Syndrome using Neural Stem Cells,2017

    • Author(s)
      Nakashima K.
    • Organizer
      Keystone Symposium
    • Place of Presentation
      Olympic Valley, USA
    • Year and Date
      2017-01-08
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Pre-existing reduced functional connectivity between cognitive control network and salience network enhances PTSD symptoms after a disaster: evidence from a longitudinal2017

    • Author(s)
      Sekiguchi A, Kotozaki Y, Sugiura M, Nakagawa S, Nouchi R, Miyauchi CM, Takeuchi H, Taki Y, Kawashima R
    • Organizer
      Society for Neuroscience 2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Uniqueness of the gaze cue in spatial anisotropy of visual attention.2017

    • Author(s)
      Eito H, Wakabayashi A
    • Organizer
      Fechner Day 2017 The 33rd Annual meeting
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] DNA methylomes identifiy transcription factor-based epigenomic signatures for timed acquisition of differentiation competence in neural stem/progenitor cells towards neuronal and glia lineages2017

    • Author(s)
      今村拓也、佐野坂司、浜崎伸彦、Chai Muh Chyi、五十嵐勝秀、大塚まき、三浦史仁、伊藤隆司、藤井信之、池尾一穂、中島欽一
    • Organizer
      4th World Congress of Reproductive Biology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Hypoxia epigenetically confers astrocytic differentiation potential on human pluripotent cell-derived neural precursor cells2017

    • Author(s)
      中島 欽一
    • Organizer
      The 72nd Fujihara Seminar Molecular Mechanism of Molding and Disruption of the Epigenomes Underlying Cellular Community
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Regulation of non-coding RNA contributes to the complete cessation of cell proliferation of neuron-like cells2017

    • Author(s)
      今村拓也、山本直樹、阿形清和、中島欽一
    • Organizer
      第43回内藤コンファレンス
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Neurogenesis: Specification of Cerebellar Progenitors2017

    • Author(s)
      Hoshino M
    • Organizer
      the 8th International Symposium of The Society for Research on the Cerebellum and Ataxia
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Generation of Pax6-IRES-EGFP knock-in mouse via cloning-free CRISPR/Cas9 system for neurodevelopmental researches2017

    • Author(s)
      Inoue YU, Hoshino M, Inoue T
    • Organizer
      Society for Neuroscience 2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Paternal aging-induced differential DNA methylation in sperm: possible effects on gene expression and behavior in offspring2017

    • Author(s)
      Osumi N, Kimura R, Yoshizaki K, Koike T, Oki S, Mochizuki K, Kikkawa T, Inada H, Matsui Y, Kono T
    • Organizer
      Society for Neuroscience 2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Paternal aging model of autism: a possible epigenetic mechanism2017

    • Author(s)
      Osumi N
    • Organizer
      Albert Einstein College of Medicine 廣井研究室セミナー
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Trans-generational transmission of ASD-like phenotypes possibly via sperm epigenetic alteration caused by paternal age2017

    • Author(s)
      Kimura R, Yoshizaki K, Koike T, Oki S, Aoki N, Mochizuki K, Kobayashi H, Kikkawa T, Inada H, Matsui Y, Kono T, Osumi N
    • Organizer
      国際自閉症カンファレンス東京2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Paternal aging affects offspring's behavior possibly via an epigenetic mechanism involving a transcriptional repressor REST2017

    • Author(s)
      Osumi N
    • Organizer
      Link_ping University-JSPS Meeting
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Voltage-sensitive dye imaging study of the input-dependent GABAergic control of the paired burst facilitation (PBF) in area CA1 of the hippocampus2017

    • Author(s)
      Tominaga T and Tominaga Y
    • Organizer
      Society for Neuroscience
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Voltage-sesitive dye signal analysis of inhibitory components in mouse perirhinal-entorrhinal cortical slices2017

    • Author(s)
      Wakayama Y, Kamada S, Yamada Y, Tominaga T, Kajiwara R
    • Organizer
      Society for Neuroscience
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Information Geometry of predictive densities and its application to Poisson regression2017

    • Author(s)
      Komaki F
    • Organizer
      Lilac International Conference of Application on Statistics (LICAS 2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Shrinkage Priors for Poisson-Based Models and Their Applications2017

    • Author(s)
      Komaki F
    • Organizer
      Joint Statistical Meetings 2017(JSM2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Neural decoding based on an infinite mixture model2017

    • Author(s)
      Shibue R and Komaki F
    • Organizer
      The 1st International Conference on Econometrics and Statistics (EcoSta 2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] A predictive approach to statistical problems with multiplicity2017

    • Author(s)
      Komaki F
    • Organizer
      CMStatistics 2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] The hippocampal beta rhythm and the computational model of it2017

    • Author(s)
      Kageyama I, Natsume K
    • Organizer
      NOLTA2017 Special Sessions
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] A Novel Practical Approach to Prosthetic Control of Continuous Multi-Fingered Kinematics with a Low-Cost Wearable sEMG Device2017

    • Author(s)
      Shibata T, Shibata T
    • Organizer
      39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] A Study on Automatic OWAS Classification of the Working Postures of a Caregiver2017

    • Author(s)
      Omure Y, Izumi H, Shibata T
    • Organizer
      39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Spatiotemporal brain transcriptome architecture in the common marmoset2016

    • Author(s)
      Go Y.
    • Organizer
      The 6th annual conference of Japan Society for Marmoset Research, Brain/MINDS international symposium
    • Place of Presentation
      東京(東京大学弥生講堂)
    • Year and Date
      2016-12-14
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Shrinkage priors for a class of Poisson regression models2016

    • Author(s)
      Komaki F.
    • Organizer
      Computational and Methodological Statistics (CMStatistics 2016)
    • Place of Presentation
      Seville, Spain
    • Year and Date
      2016-12-10
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Role of Meis1 in the cerebellar development2016

    • Author(s)
      Owa T, Taya S, Miyashita S, Nishioka T, Kaibuchi K, Hoshino M:
    • Organizer
      Neuroscience2016
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-14
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Network plasticity facilitating the neural excitation propagation between the perirhinal and entorhinal cortices as revealed by voltage-sensitive dye imaging2016

    • Author(s)
      R. Kajiwara, Y. Wakayama, Y. Tominaga, T. Tominaga
    • Organizer
      Neuroscience 2016
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-14
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Activation of GABAA-receptors by high-frequency stimuli causes paired burst facilitations in area CA1 of the hippocampal slice2016

    • Author(s)
      Tominaga T and Tominaga Y.
    • Organizer
      Neuroscience 2016
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-14
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] aternal aging-induced differential DNA methylation in sperm: possible transgenerational effects on gene expression and behavior in offspring,2016

    • Author(s)
      Kimura R., Yoshizaki K., Koike T., Koike K., Kikkawa T., Inada H., Matsui Y., Kono T. and Osumi N.
    • Organizer
      Neuroscience 2016
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-13
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] The characteristics of the cortical functional networks in individual infants2016

    • Author(s)
      Homae, F., Watanabe, H., & Taga, G.
    • Organizer
      The Society for Functional Near Infrared Spectroscopy 2016 Biennial Meeting
    • Place of Presentation
      Paris, France
    • Year and Date
      2016-10-16
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Spatiotemporal gene expression trajectory in the human and non-human ape brains2016

    • Author(s)
      Go Y.
    • Organizer
      The 6th Joint CIN-NIPS International Symposium
    • Place of Presentation
      Tubingen, Germany
    • Year and Date
      2016-10-11
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Paternal aging-induced differential DNA methylation in sperm: possible transgenerational effects on gene expression and behavior.2016

    • Author(s)
      Osumi N.
    • Organizer
      Genome Imprinting Epigenetics and Physiologizal Functions
    • Place of Presentation
      Erice, Italy
    • Year and Date
      2016-10-06
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Paternal aging affects offspring’s behavior: its significance and possible underlying transgenerational epigenetics.2016

    • Author(s)
      Osumi N.
    • Organizer
      The 19th KSBNS Annual Meeting
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2016-09-28
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Book] 個性学入門 : 個性創発の科学2021

    • Author(s)
      保前 文高,大隅 典子,原 塑,若林 明雄,駒木 文保,村山 美穂,郷 康広,星野 幹雄,岡田 泰和,河田 雅圭,佐藤大気,菅野 康太,冨永 貴志,今吉 格,地村 弘二,柴田 智広,松原 周蔵,岩本 昌和,中島欽一,片平 健太郎
    • Total Pages
      232
    • Publisher
      朝倉書店
    • ISBN
      9784254102956
    • Related Report
      2021 Annual Research Report
  • [Book] 壊れた脳と生きる2021

    • Author(s)
      鈴木匡子,鈴木大介
    • Total Pages
      288
    • Publisher
      筑摩書房
    • ISBN
      9784480684028
    • Related Report
      2021 Annual Research Report
  • [Book] 望星2020

    • Author(s)
      大隅 典子
    • Total Pages
      120
    • Publisher
      東海教育研究所
    • Related Report
      2020 Research-status Report
  • [Book] 当事者研究 等身大の<わたし>の発見と回復2020

    • Author(s)
      熊谷 晋一郎
    • Total Pages
      280
    • Publisher
      岩波書店
    • Related Report
      2020 Research-status Report
  • [Remarks] 平成28年度採択進学術領域「個性」創発脳

    • URL

      http://www.koseisouhatsu.jp/

    • Related Report
      2021 Annual Research Report
  • [Remarks] ニュースレター総括号

    • URL

      http://www.koseisouhatsu.jp/activity/release/20210927_newsletter_summary/images/newsletter_summary.pdf

    • Related Report
      2021 Annual Research Report
  • [Remarks] 「個性」創発脳

    • URL

      http://www.koseisouhatsu.jp/

    • Related Report
      2020 Research-status Report
  • [Remarks] ニュースレターVol.8

    • URL

      http://www.koseisouhatsu.jp/activity/release/20200918_newsletter_vol8/images/newsletter_vol8.pdf

    • Related Report
      2020 Research-status Report
  • [Remarks] ニュースレターVol.9

    • URL

      http://www.koseisouhatsu.jp/activity/release/20210318_newsletter_vol9/images/newsletter_vol9.pdf

    • Related Report
      2020 Research-status Report
  • [Remarks] 多様な「個性」を創発する脳システムの総合的理解

    • URL

      http://www.koseisouhatu.jp

    • Related Report
      2018 Research-status Report
  • [Remarks] 多様な「個性」を創発する脳システムの統合的理解 【領域略称「個性」創発脳】

    • URL

      http://www.koseisouhatsu.jp/index.html

    • Related Report
      2017 Research-status Report
  • [Remarks] 平成28年度採択新学術領域 「個性」創発脳

    • URL

      http://www.koseisouhatsu.jp

    • Related Report
      2016 Research-status Report

URL: 

Published: 2016-07-04   Modified: 2023-01-30  

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