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Strategies for research policies in the area

Administrative Group

Project AreaConquering cancer through neo-dimensional systems understanding
Project/Area Number 15H05907
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionThe University of Tokyo

Principal Investigator

MIYANO SATORU  東京大学, 医科学研究所, 教授 (50128104)

Co-Investigator(Kenkyū-buntansha) 稲澤 譲治  東京医科歯科大学, 難治疾患研究所, 教授 (30193551)
高橋 隆  愛知県がんセンター(研究所), 総長, 総長 (50231395)
武藤 香織  東京大学, 医科学研究所, 教授 (50345766)
小川 誠司  京都大学, 医学研究科, 教授 (60292900)
岡田 随象  大阪大学, 医学系研究科, 教授 (70727411)
Project Period (FY) 2015-06-29 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥42,120,000 (Direct Cost: ¥32,400,000、Indirect Cost: ¥9,720,000)
Fiscal Year 2019: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2018: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2017: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2016: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2015: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Keywordsがん / システム生物学 / 統計的モデリング / バイオインフォマティクス / 人工知能 / ゲノム科学
Outline of Final Research Achievements

The area of "systems cancer," which combines cancer biology and cancer research with computational system biology, is deepened by utilizing supercomputers and artificial intelligence, and at the same time, is a patient-centered principle that responds to innovations in genome analysis. By fusing ELSI research, we managed to create a new dimension of cancer research fusion area. We published a series of newsletters and held symposia. In addition, a series of seminars on large-scale data analysis and analysis technology using supercomputers was held.

Academic Significance and Societal Importance of the Research Achievements

総括班のマネジメントにより、極めてインパクトのあるがん研究の科学的成果を創出できた。多彩なアウトリーチ活動により、海外も含め社会とのコミュニケーションが図られ、「がん」と「人工知能・スーパーコンピュータ」、そして「ELSI研究」が融合した領域の誕生が社会的に認識された。2020年3月に日本科学未来館から行った動画配信は、7000人以上の参加と2000件以上のメッセージがあり、象徴的イベントとなった。領域外のがん研究者、バイオインフォマティクス研究者、人文系研究者に対して、この新次元へと深化していく本領域のインパクトが伝わった。

Report

(6 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (44 results)

All 2020 2017 2016 Other

All Int'l Joint Research (12 results) Presentation (9 results) (of which Int'l Joint Research: 7 results,  Invited: 9 results) Book (1 results) Remarks (18 results) Funded Workshop (4 results)

  • [Int'l Joint Research] Montreal Heart Institute(カナダ)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Seoul National University/National Cancer Center(韓国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Wellcome Sanger Institute(英国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Karolinska Institutet(スウェーデン)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Harvard Medical School(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Harvard Medical School/Ichan School of Medicine at Mount Sinai/University of Michigan(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] カロリンスカ研究所(スウェーデン)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] チュラロンコン大学(タイ)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] The Wellcome Trust Sanger Institute(英国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Seoul National University/University of Ulsan College(韓国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2018 Annual Research Report
  • [Presentation] On the origin of cancer2020

    • Author(s)
      Seishi Ogawa
    • Organizer
      International Conference on Cancer Systems Biology Beyond
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter-enhancer interaction2020

    • Author(s)
      Takashi Takahashi
    • Organizer
      International Conference on Cancer Systems Biology Beyond
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Statistical genetics, disease biology, and drug discovery2020

    • Author(s)
      Yukinori Okada
    • Organizer
      International Conference on Cancer Systems Biology Beyond
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] MicroRNA Therapeutics in Precision Cancer Medicine (PCM)2020

    • Author(s)
      Johji Inazawa
    • Organizer
      International Conference on Cancer Systems Biology Beyond
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] What Public Concerns Exist Regarding Cancer Genomic Medicine? The Japanese Experience and Beyond2020

    • Author(s)
      Kaori Muto, Akiko Nagai
    • Organizer
      International Conference on Cancer Systems Biology Beyond
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Integrative Nutriomics Approach for understanding Cancer and Metabolism2020

    • Author(s)
      Tsuyoshi Osawa
    • Organizer
      International Conference on Cancer Systems Biology Beyond
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cancer Big Data Challenges by Supercomputers and Artificial Intelligence2020

    • Author(s)
      Satoru Miyano
    • Organizer
      International Conference on Cancer Systems Biology Beyond
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] スパコンを使ってゲノムの未開のジャングルから鍵遺伝子を探す2016

    • Author(s)
      高橋 隆
    • Organizer
      システム癌新次元公開講演会「人工知能とスーパーコンピュータでがんにチャレンジ」
    • Place of Presentation
      東京・お台場「未来科学館」
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 人工知能とスパコンで変わるがん研究と医療2016

    • Author(s)
      宮野 悟
    • Organizer
      システム癌新次元公開講演会「人工知能とスーパーコンピュータでがんにチャレンジ」
    • Place of Presentation
      東京・お台場「未来科学館」
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Book] 実験医学増刊Vol.34-No.5 「ビッグデータ 変革する生命科学・医療」 激増するオミクスデータ・医療データとどう向き合い、どう活用すべきか?2016

    • Author(s)
      永井良三,宮野 悟,大江和彦/編
    • Total Pages
      223
    • Publisher
      羊土社
    • Related Report
      2015 Annual Research Report
  • [Remarks] システム癌新次元ホームページ

    • URL

      http://neosystemscancer.hgc.jp/

    • Related Report
      2019 Annual Research Report
  • [Remarks] ISPCM Annual Meeting 2020

    • URL

      http://www.tmd.ac.jp/mri/cgen/framepage.htm

    • Related Report
      2019 Annual Research Report
  • [Remarks] Int'l Conf, on Cancer Systems Biology Beyond

    • URL

      http://neosystemscancer.hgc.jp/csbbeyond

    • Related Report
      2019 Annual Research Report
  • [Remarks] トークセッション「どう変わる!?がんとの向き合い方──人とAIでひらく新たな医療」

    • URL

      https://www.miraikan.jst.go.jp/event/2003081325434.html

    • Related Report
      2019 Annual Research Report
  • [Remarks] トークセッション&ワークショップ「どう変わる!?がんとの向き合い方──ゲノム研究で広がる可能性」

    • URL

      https://www.miraikan.jst.go.jp/event/2002161325421.html

    • Related Report
      2019 Annual Research Report
  • [Remarks]

    • URL

      http://neosystemscancer.hgc.jp/

    • Related Report
      2018 Annual Research Report
  • [Remarks]

    • URL

      http://neosystemscancer.hgc.jp/outreach#%E3%83%8B%E3%83%A5%E3%83%BC%E3%82%B9%E3%83%AC%E3%82%BF%E3%83%BC

    • Related Report
      2018 Annual Research Report
  • [Remarks]

    • URL

      http://iwsg2018.hgc.jp/

    • Related Report
      2018 Annual Research Report
  • [Remarks] 新学術領域「システム癌新次元」

    • URL

      http://neosystemscancer.hgc.jp/

    • Related Report
      2017 Annual Research Report
  • [Remarks] 新学術領域「システム癌新次元」ニュースレター

    • URL

      http://neosystemscancer.hgc.jp/outreach#%E3%83%8B%E3%83%A5%E3%83%BC%E3%82%B9%E3%83%AC%E3%82%BF%E3%83%BC

    • Related Report
      2017 Annual Research Report
  • [Remarks] International Workshop for Systems Genetics

    • URL

      http://iwsg2017.hgc.jp/

    • Related Report
      2017 Annual Research Report
  • [Remarks] Int'l Conference for Precision Cancer Medicine

    • URL

      http://www.tmd.ac.jp/mri/cgen/framepage.htm

    • Related Report
      2017 Annual Research Report
  • [Remarks] システム癌新次元 ニュースレター No.2

    • URL

      http://neosystemscancer.hgc.jp/_media/%E3%82%B7%E3%82%B9%E3%83%86%E3%83%A0%E7%99%8C%E6%96%B0%E6%AC%A1%E5%85%83newsletterno2.pdf

    • Related Report
      2016 Annual Research Report
  • [Remarks] システム癌新次元 ニュースレター No.3

    • URL

      http://neosystemscancer.hgc.jp/_media/%E3%82%B7%E3%82%B9%E3%83%86%E3%83%A0%E7%99%8C%E6%96%B0%E6%AC%A1%E5%85%83newsletterno3.pdf

    • Related Report
      2016 Annual Research Report
  • [Remarks] システム癌新次元 ニュースレター No.4

    • URL

      http://neosystemscancer.hgc.jp/_media/%E3%82%B7%E3%82%B9%E3%83%86%E3%83%A0%E7%99%8C%E6%96%B0%E6%AC%A1%E5%85%83newsletterno4.pdf

    • Related Report
      2016 Annual Research Report
  • [Remarks] システム癌新次元 ニュースレター No.5

    • URL

      http://neosystemscancer.hgc.jp/_media/%E3%82%B7%E3%82%B9%E3%83%86%E3%83%A0%E7%99%8C%E6%96%B0%E6%AC%A1%E5%85%83newsletterno5.pdf

    • Related Report
      2016 Annual Research Report
  • [Remarks] システム癌新次元ホームページ

    • URL

      http://neosystemscancer.hgc.jp

    • Related Report
      2016 Annual Research Report
  • [Remarks] 新学術領域研究「システム癌新次元」ホームページ

    • URL

      http://neosystemscancer.hgc.jp/

    • Related Report
      2015 Annual Research Report
  • [Funded Workshop] The International Conference on Cancer Systems Biology Beyond2020

    • Related Report
      2019 Annual Research Report
  • [Funded Workshop] International Workshop for Systems Genetics2017

    • Related Report
      2017 Annual Research Report
  • [Funded Workshop] International Conference for Precision Cancer Medicine2017

    • Related Report
      2017 Annual Research Report
  • [Funded Workshop] The International Workshop on Bioinformatics and Systems Biology 20162016

    • Place of Presentation
      東大医科学研究所&国立科学博物館
    • Year and Date
      2016-08-07
    • Related Report
      2016 Annual Research Report

URL: 

Published: 2015-07-02   Modified: 2022-11-04  

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