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Integral Understanding of Life-regulation Mechanism from "SPACE"

Administrative Group

Project Area"LIVING IN SPACE" - Integral Understanding of life-regulation mechanism from "SPACE"
Project/Area Number 15H05935
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionJapan Aerospace EXploration Agency

Principal Investigator

Furukawa Satoshi  国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 上席研究開発員 (20726260)

Co-Investigator(Kenkyū-buntansha) 根井 充  国立研究開発法人量子科学技術研究開発機構, 本部 安全管理部, 部長(任常) (10164659)
松崎 一葉  筑波大学, 医学医療系, 教授 (10229453)
日出間 純  東北大学, 生命科学研究科, 准教授 (20250855)
東端 晃  国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 主任研究開発員 (30360720)
東谷 篤志  東北大学, 生命科学研究科, 教授 (40212162)
成瀬 恵治  岡山大学, 医歯薬学総合研究科, 教授 (40252233)
瀬原 淳子  京都大学, ウイルス・再生医科学研究所, 連携教授 (60209038)
高橋 昭久  群馬大学, 重粒子線医学推進機構, 教授 (60275336)
井上 夏彦  国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 主任研究開発員 (60277811)
長瀬 博  筑波大学, 国際統合睡眠医科学研究機構, 教授 (70383651)
森田 啓之  岐阜大学, 大学院医学系研究科, 教授 (80145044)
岩崎 賢一  日本大学, 医学部, 教授 (80287630)
那須 正夫  大阪大谷大学, 薬学研究科, 教授 (90218040)
村井 正  国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 参事 (10748958)
嶋津 徹  国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 主幹研究開発員 (20639158)
村上 敬司  国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 主幹研究開発員 (40421870)
Project Period (FY) 2015-06-29 – 2020-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥72,410,000 (Direct Cost: ¥55,700,000、Indirect Cost: ¥16,710,000)
Fiscal Year 2019: ¥14,820,000 (Direct Cost: ¥11,400,000、Indirect Cost: ¥3,420,000)
Fiscal Year 2018: ¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2017: ¥15,340,000 (Direct Cost: ¥11,800,000、Indirect Cost: ¥3,540,000)
Fiscal Year 2016: ¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2015: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Keywords宇宙 / 微小重力 / ストレス / 放射線 / 微生物 / 無重力 / 特殊環境 / 社会医学 / 宇宙医学 / 宇宙環境 / 放射線影響 / 可塑性 / 破綻
Outline of Final Research Achievements

During a long-term stay in space, physical stress of zero gravity causes muscle atrophy and bone loss, psychological stress by an enclosed environment brings about biological rhythm dysfunction, environmental risks like space radiation exposure induce DNA mutation. These issues need to be resolved in an era of challenging an ultra-long-term stay in space with human exploration to Mars. At the same time, deep understanding of the issues will help contribute to maintaining homeostasis of life in our super-aged, stressful society on Earth, leading to healthy aging and longevity.
Our team of experts attempted to integrally understand the plasticity and failure of life forms on Earth. Nearly 300 peer-reviewed scientific papers were published in the 5-year research period. Joint researches were conducted with more than 12 foreign research institutes from more than 6 countries. Young researchers were fostered.

Academic Significance and Societal Importance of the Research Achievements

重力影響による骨・筋・前庭・循環系・免疫機能の恒常性維持と破綻を、宇宙・地上実験にて、細胞、組織から器官、それらのネットワーク、個体レベルで、重力感受と適応応答機構ならびにその分子基盤を特定した。また、ストレスと関連が深い睡眠・覚醒の領域において新たな睡眠診断デバイス(簡易であり、地上の生活にも大いに役立つ)、不眠症治療薬の評価分析、眠気の分子的実体を捉えるなど世界トップレベルでの研究を展開・達成した。さらに、無重力と閉鎖環境の複合影響を研究するため、新規装置開発、メタゲノム解析、蛍光プローブやバイオイメージングなど新たなモニタリングシステムの開発も行った。

Report

(6 results)
  • 2020 Final Research Report ( PDF )
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report

Research Products

(836 results)

All 2021 2020 2019 2018 2017 2016 2015 Other

All Int'l Joint Research (21 results) Journal Article (253 results) (of which Int'l Joint Research: 112 results,  Peer Reviewed: 248 results,  Open Access: 178 results,  Acknowledgement Compliant: 33 results) Presentation (514 results) (of which Int'l Joint Research: 209 results,  Invited: 194 results) Book (35 results) Remarks (4 results) Patent(Industrial Property Rights) (7 results) Funded Workshop (2 results)

  • [Int'l Joint Research] バージニア大学/コロラド州立大学/Prairie View A&M University(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] ドイツ航空宇宙センター(ドイツ)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] パスツール研究所(フランス)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] バルセロナ大学/Pompeu Fabra University(スペイン)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] ベルゲン大学(ノルウェー)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] バージニア大学/コロラド州立大学/Prairie View A&M University(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] ドイツ航空宇宙センター(ドイツ)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] パスツール研究所(フランス)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] バルセロナ大学/Pompeu Fabra University(スペイン)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] ベルゲン大学(ノルウェー)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] スタンフォード大学/ハーバード大学/バージニア大学(米国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] ドイツ航空宇宙センター/マールブルグ大学/Institute of Aerospace Medicine(ドイツ)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] パスツール研究所(フランス)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Institute of Science and Technology(オーストリア)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] スウェーデン農業科学大学(スウェーデン)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] スタンフォード大学/フロリダ州立大学/バージニア大学(米国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] German Aerospace Center/マールブルグ大学/Institute of Aerospace Medicine(ドイツ)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] パスツール研究所(フランス)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] Institute of Science and Technology(オーストリア)

    • Related Report
      2016 Annual Research Report
  • [Journal Article] GABA from vasopressin neurons regulates the time at which suprachiasmatic nucleus molecular clocks enable circadian behavior2021

    • Author(s)
      Maejima Takashi、Tsuno Yusuke、Miyazaki Shota、Tsuneoka Yousuke、Hasegawa Emi、Islam Md Tarikul、Enoki Ryosuke、Nakamura Takahiro J.、Mieda Michihiro
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 6 Pages: 1-18

    • DOI

      10.1073/pnas.2010168118

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Identification of fungi isolated from astronaut nasal and pharyngeal smears and saliva2021

    • Author(s)
      Kazuo Satoh, Takashi Yamazaki, Satoshi Furukawa, Chiaki Muka, Koichi Makimura
    • Journal Title

      Microbiol Immunol

      Volume: 65(2) Issue: 2 Pages: 89-94

    • DOI

      10.1111/1348-0421.12872

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Self‐Emergent Protocells Generated in an Aqueous Solution with Binary Macromolecules through Liquid‐Liquid Phase Separation2020

    • Author(s)
      Sakuta Hiroki, Fujita Fumika, Hamada Tsutomu, Hayashi Masahito, Takiguchi Kingo, Tsumoto Kanta, Yoshikawa Kenichi
    • Journal Title

      ChemBioChem

      Volume: 21 Issue: 23 Pages: 3323-3328

    • DOI

      10.1002/cbic.202000344

    • NAID

      120006940266

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ubiquitin ligase Cbl-b and inhibitory Cblin peptides2020

    • Author(s)
      Takeshi Nikawa, Kazumi Ishidoh
    • Journal Title

      BBA - Proteins and Proteomics

      Volume: 1868 Issue: 11 Pages: 140495-140495

    • DOI

      10.1016/j.bbapap.2020.140495

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] How does spaceflight affect acquired immune system?2020

    • Author(s)
      T. Akiyama, K. Horie, E. Hinoi, M. Hiraiwa, A. Kato, Y. Maekawa, A. Takahashi, S. Furukawa
    • Journal Title

      NPJ Microgravity.

      Volume: 0 Issue: 1 Pages: 1-7

    • DOI

      10.1038/s41526-020-0104-1

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Transient and lineage-restricted requirement of Ebf3 for sternum ossification.2020

    • Author(s)
      Kuriki M, Sato F, Arai HN, Sogabe M, Kaneko M, Kiyonari H, Kawakami K, Yoshimoto Y, Shukunami C, Sehara-Fujisawa A.
    • Journal Title

      Development

      Volume: 147 Issue: 9

    • DOI

      10.1242/dev.186239

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Expression of Hey2 transcription factor in the early embryonic ventricles is controlled through a distal enhancer by Tbx20 and Gata transcription factors2020

    • Author(s)
      Ihara Dai、Watanabe Yusuke、Seya Daiki、Arai Yuji、Isomoto Yoshie、Nakano Atsushi、Kubo Atsushi、Ogura Toshihiko、Kawamura Teruhisa、Nakagawa Osamu
    • Journal Title

      Developmental Biology

      Volume: 461 Issue: 2 Pages: 124-131

    • DOI

      10.1016/j.ydbio.2020.02.001

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Myelination during fracture healing in vivo in myelin protein zero (p0) transgenic medaka line2020

    • Author(s)
      Dodo Y, Chatani M, Azetsu Y, Hosonuma M, Karakawa A, Sakai N, Negishi-Koga T, Tsuji M, Inagaki K, Kiuchi Y, Takami M
    • Journal Title

      Bone

      Volume: 133 Pages: 115225-115225

    • DOI

      10.1016/j.bone.2020.115225

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Generation and evaluation of a transgenic zebrafish for tissue-specific expression of a dominant-negative Rho-associated protein kinase-2.2020

    • Author(s)
      Iida A, Wang Z, Hondo E, Sehara-Fujisawa A.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 525 Issue: 1 Pages: 8-13

    • DOI

      10.1016/j.bbrc.2020.02.055

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of N-methyl-D-aspartate receptor antagonist MK-801 (dizocilpine) on bone homeostasis in mice2020

    • Author(s)
      Kiyohara S, Sakai N, Handa K, Yamakawa T, Ishikawa K, Chatani M, Karakawa A, Azetsu Y, Munakata M, Ozeki M, Negishi-Koga T, Takami M
    • Journal Title

      J Oral Biosci

      Volume: - Issue: 2 Pages: 131-138

    • DOI

      10.1016/j.job.2020.03.003

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Increased hydrostatic pressure induces nuclear translocation of DAF-16/FOXO in C.elegans2020

    • Author(s)
      Watanabe Naoshi、Morimatsu Masatoshi、Fujita Ayano、Teranishi Mika、Sudevan Surabhi、Watanabe Masaru、Iwasa Hiroaki、Hata Yutaka、Kagi Hiroyuki、Nishiyama Masayoshi、Naruse Keiji、Higashitani Atsushi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 523 Issue: 4 Pages: 853-858

    • DOI

      10.1016/j.bbrc.2020.01.047

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Long-duration spaceflight alters estimated intracranial pressure and cerebral blood velocity2020

    • Author(s)
      Ken-ichi Iwasaki, Yojiro Ogawa, Takuya Kurazumi, Syed M. Imaduddin, Chiaki Mukai, Satoshi Furukawa, Ryo Yanagida, Tomokazu Kato, Toru Konishi, Ari Shinojima, Benjamin D. Levine, Thomas Heldt
    • Journal Title

      The Journal of Physiology

      Volume: 599(4) Issue: 4 Pages: 1067-1081

    • DOI

      10.1113/jp280318

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Early high-fat feeding improves histone modifications of skeletal muscle at middle-age in mice.2020

    • Author(s)
      Yoshie T, Saito C, Kawano F
    • Journal Title

      Lab. Anim. Res.

      Volume: 36 Issue: 1 Pages: 25-25

    • DOI

      10.1186/s42826-020-00060-2

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Roles of olfactomedin 1 in muscle and bone alterations induced by gravity change in mice2020

    • Author(s)
      Shimode T, Kawao N, Morita H, Ishida M, Takafuji Y, Kaji H
    • Journal Title

      Calcified Tissue International

      Volume: 27 Issue: 2 Pages: 180-190

    • DOI

      10.1007/s00223-020-00710-6

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Utriculo-ocular pathway dysfunction is more frequent in vestibular migraine than probable vestibular migraine.2020

    • Author(s)
      Fujimoto C, Kamogashira T, Takenouchi S, Kinoshita M, Sugasawa K, Kawahara T, Yamasoba T, Iwasaki S
    • Journal Title

      J Neurol

      Volume: 267 Issue: 8 Pages: 2340-2346

    • DOI

      10.1007/s00415-020-09851-y

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Peripherally administered cisplatin activates a parvocellular neuronal subtype expressing arginine vasopressin and enhanced green fluorescent protein in the paraventricular nucleus of a transgenic rat2020

    • Author(s)
      Akiyama Y, Yoshimura M, Ueno H, Sanada K, Tanaka K, Sonoda S, Nishimura H, Nishimura K, Motojima Y, Saito R, Maruyama T, Hirata K, Uezono Y, Ueta Y
    • Journal Title

      The Journal of Physiological Sciences

      Volume: 70 Issue: 1 Pages: 9-9

    • DOI

      10.1186/s12576-020-00764-z

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Discovery of attenuation effect of orexin 1 receptor to aversion of nalfurafine: Synthesis and evaluation of D-nor-nalfurafine derivatives and analyses of the three active conformations of nalfurafine2020

    • Author(s)
      Nagumo Yasuyuki、Katoh Koki、Iio Keita、Saitoh Tsuyoshi、Kutsumura Noriki、Yamamoto Naoshi、Ishikawa Yukiko、Irukayama-Tomobe Yoko、Ogawa Yasuhiro、Baba Takeshi、Tanimura Ryuji、Yanagisawa Masashi、Nagase Hiroshi
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 30 Issue: 17 Pages: 127360-127360

    • DOI

      10.1016/j.bmcl.2020.127360

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need2020

    • Author(s)
      Minjeong Park, Chika Miyoshi, Tomoyuki Fujiyama, Miyo Kakizaki, Aya Ikkyu, Takato Honda, Jinhwan Choi, Fuyuki Asano, Seiya Mizuno, Satoru Takahashi, Masashi Yanagisawa, Hiromasa Funato
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 8676-8676

    • DOI

      10.1038/s41598-020-65647-0

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Myonectin inhibits the differentiation of osteoblasts and osteoclasts in mouse cells2020

    • Author(s)
      Kawaguchi M, Kawao N, Takafuji Y, Ishida M, Kaji H.
    • Journal Title

      Heliyon.

      Volume: 6 Issue: 5 Pages: e03967-e03967

    • DOI

      10.1016/j.heliyon.2020.e03967

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Extracellular vesicles secreted from mouse muscle cells suppress osteoclast formation: Roles of mitochondrial energy metabolism.2020

    • Author(s)
      Takafuji Y, Tatsumi K, Ishida M, Kawao N, Okada K, Kaji H.
    • Journal Title

      Bone

      Volume: 134 Pages: 115298-115298

    • DOI

      10.1016/j.bone.2020.115298

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] VGLUT2-expressing neurons in the vestibular nuclear complex mediate gravitational stress-induced hypothermia in mice2020

    • Author(s)
      Abe C, Yamaoka Y, Maejima Y, Mikami T, Yokota S, Yamanaka A, Morita H
    • Journal Title

      Communications Biology

      Volume: 227 Issue: 1 Pages: 1-13

    • DOI

      10.1038/s42003-020-0950-0

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Adaptive responses of histone modifications to resistance exercise in human skeletal muscle2020

    • Author(s)
      Lim Changhyun、Shimizu Junya、Kawano Fuminori、Kim Hyo Jeong、Kim Chang Keun
    • Journal Title

      PLOS ONE

      Volume: 15 Issue: 4 Pages: e0231321-e0231321

    • DOI

      10.1371/journal.pone.0231321

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Roles of Dkk2 in the linkage from muscle to bone during mechanical unloading in mice2020

    • Author(s)
      Kawao N, Morita H, Iemura S, Ishida M, Kaji H
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 7 Pages: 2547-2547

    • DOI

      10.3390/ijms21072547

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A new method with an explant culture of the utricle for assessing the influence of exposure to low frequency noise on the vestibule2020

    • Author(s)
      Ohgami N, He T, Negishi-Oshino R, Gu Y, Li X, Kato M
    • Journal Title

      J Toxicol Environ Health, Part A

      Volume: 83(5) Issue: 5 Pages: 215-218

    • DOI

      10.1080/15287394.2020.1746945

    • NAID

      120006869634

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Combined Environment Simulator for Low-Dose-Rate Radiation and Partial Gravity of Moon and Mars2020

    • Author(s)
      Takahashi Akihisa、Yamanouchi Sakuya、Takeuchi Kazuomi、Takahashi Shogo、Tashiro Mutsumi、Hidema Jun、Higashitani Atsushi、Adachi Takuya、Zhang Shenke、Guirguis Fady Nagy Lotfy、Yoshida Yukari、Nagamatsu Aiko、Hada Megumi、Takeuchi Kunihito、Takahashi Tohru、Sekitomi Yuji
    • Journal Title

      Life

      Volume: 10 Issue: 11 Pages: 274-274

    • DOI

      10.3390/life10110274

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Simultaneous Exposure of Cultured Human Lymphoblastic Cells to Simulated Microgravity and Radiation Increases Chromosome Aberrations2020

    • Author(s)
      Sakuya Yamanouchi, Jordan Rhone, Jian-Hua Mao, Keigi Fujiwara, Premkumar B. Saganti, Akihisa Takahashi, and Megumi Hada
    • Journal Title

      life

      Volume: 10(9) Issue: 9 Pages: 187-187

    • DOI

      10.3390/life10090187

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Targeted Central Nervous System Irradiation of Caenorhabditis elegans Induces a Limited Effect on Motility2020

    • Author(s)
      *Michiyo Suzuki, Zu Soh, Hiroki Yamashita, Toshio Tsuji, Tomoo Funayama
    • Journal Title

      Biology

      Volume: 9 Issue: 9 Pages: 289-289

    • DOI

      10.3390/biology9090289

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Early induction and increased risk of precursor B-cell neoplasms after exposure of infant or young-adult mice to ionizing radiation2020

    • Author(s)
      Hirotaka Tachibana1,3, Takamitsu Morioka1,*, Kazuhiro Daino1, Yi Shang1, Mari Ogawa1, Misuzu Fujita1, Akira Matsuura3,4, Hiroyuki Nogawa3,4, Yoshiya Shimada2,† and Shizuko Kakinuma1,*
    • Journal Title

      Journal of radiation research

      Volume: 61(5) Issue: 5 Pages: 648-656

    • DOI

      10.1093/jrr/rraa055

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Nrf2 contributes to the weight gain of mice during space travel2020

    • Author(s)
      Suzuki, T., et al., Koshiba, S. et al., Yamamoto, M.(合計37名、本研究者は18番目)
    • Journal Title

      Communications Biology

      Volume: 3 Issue: 1 Pages: 496-496

    • DOI

      10.1038/s42003-020-01227-2

    • NAID

      120007161347

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The skin mycobiome of an astronaut during a 1-year stay on the International Space Station2020

    • Author(s)
      *Takashi Sugita , Takashi Yamazaki , Otomi Cho , Satoshi Furukawa and Chiaki Mukai
    • Journal Title

      Medical Mycology

      Volume: N/A Issue: 1 Pages: 106-109

    • DOI

      10.1093/mmy/myaa067

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chloroplast Autophagy and Ubiquitination Combine to Manage Oxidative Damage and Starvation Responses2020

    • Author(s)
      Kikuchi Yuta、Nakamura Sakuya、Woodson Jesse D.、Ishida Hiroyuki、Ling Qihua、Hidema Jun、Jarvis R. Paul、Hagihara Shinya、Izumi Masanori
    • Journal Title

      Plant Physiology

      Volume: 183 Issue: 4 Pages: 1531-1544

    • DOI

      10.1104/pp.20.00237

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Iron Ladies - How Desiccated Asexual Rotifer Adineta vaga Deal With X-Rays and Heavy Ions?2020

    • Author(s)
      Hespeels B, Penninckx S, Cornet V, Bruneau L, Bopp C, Baumle V, Redivo B, Heuskin AC, Moeller R, Fujimori A, Stephane Lucas, Doninck KV.
    • Journal Title

      Frontiers in Microbiology

      Volume: 11 Pages: 1-14

    • DOI

      10.3389/fmicb.2020.01792

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The Responses of the Black Fungus Cryomyces Antarcticus to High Doses of Accelerated Helium Ions Radiation within Martian Regolith Simulants and Their Relevance for Mars2020

    • Author(s)
      Pacelli C, Cassaro A, Aureli L, Moeller R, Fujimori A, Onofri S.
    • Journal Title

      life

      Volume: 10 Issue: 8 Pages: 1-14

    • DOI

      10.3390/life10080130

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome.2020

    • Author(s)
      Miyamoto T, Hosoba K, Itabashi T, Iwane AH, Akutsu AN, Ochiai H, Saito Y, Yamamoto T, Matsuura S
    • Journal Title

      EMBO Journal

      Volume: - Issue: 12

    • DOI

      10.15252/embj.2019103499

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Space radiation biology for “Living in Space”2020

    • Author(s)
      Furukawa S, Nagamatsu A, Nenoi M, Fujimori A, Kakinuma S, Katsube T, Wang B, Tsuruoka C, Shirai T, Nakamura AJ, Sakaue-Sawano A, Miyawaki A, Harada H, Kobayashi M, Kobayashi J, Kunieda T, Funayama T, Suzuki M, Miyamoto T, Hidema J, Yoshida Y, Takahashi A.
    • Journal Title

      BioMed Res Int.

      Volume: 2020 Pages: 4703286-4703286

    • DOI

      10.1155/2020/4703286

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] FXR1 is a novel MRE11-binding partner and participates in oxidative stress responses.2020

    • Author(s)
      Qi F, Meng Q, Hayashi I, Kobayashi J
    • Journal Title

      J Radiat Res.

      Volume: in press Issue: 3 Pages: 368-375

    • DOI

      10.1093/jrr/rraa011

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Process Description of an Unconventional Biofilm Formation by Bacterial Cells Autoagglutinating through Sticky, Long, and Peritrichate Nanofibers2020

    • Author(s)
      Furuichi Yoshihide、Yoshimoto Shogo、Inaba Tomohiro、Nomura Nobuhiko、Hori Katsutoshi
    • Journal Title

      Environmental Science & Technology

      Volume: 54 Issue: 4 Pages: 2520-2529

    • DOI

      10.1021/acs.est.9b06577

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Very high sensitivity of African rice to artificial ultraviolet-B radiation caused by genotype and quantity of cyclobutane pyrimidine dimer photolyase2020

    • Author(s)
      Mmbando GS, Teranishi M, Hidema J.
    • Journal Title

      Sci Rep

      Volume: 10 Issue: 1 Pages: 3158-3158

    • DOI

      10.1038/s41598-020-59720-x

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion2020

    • Author(s)
      Tomoo Funayama, Tetsuya Sakashita, Michiyo Suzuki, Yuichiro Yokota, Nobumasa Miyawaki, Hirotsugu Kashiwagi, Takahiro Satoh, Satoshi Kurashima
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

      Volume: 465 Pages: 101-109

    • DOI

      10.1016/j.nimb.2019.12.028

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Applications of Genome Editing Technology in Research on Chromosome Aneuploidy Disorders2020

    • Author(s)
      Akutsu Silvia Natsuko、Fujita Kazumasa、Tomioka Keita、Miyamoto Tatsuo、Matsuura Shinya
    • Journal Title

      Cells

      Volume: 9 Issue: 1 Pages: 239-239

    • DOI

      10.3390/cells9010239

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Identification of a herpes simplex virus 1 gene encoding neurovirulence factor by chemical proteomics2020

    • Author(s)
      Kato Akihisa、Adachi Shungo、Kawano Shuichi、Takeshima Kousuke、Watanabe Mizuki、Kitazume Shinobu、Sato Ryota、Kusano Hideo、Koyanagi Naoto、Maruzuru Yuhei、Arii Jun、Hatta Tomohisa、Natsume Tohru、Kawaguchi Yasushi
    • Journal Title

      Nature Communications

      Volume: 11 Issue: 1 Pages: 4894-4894

    • DOI

      10.1038/s41467-020-18718-9

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Growth and physiological characteristics of wasabi plantlets cultured by photoautotrophic micropropagation at different temperatures2020

    • Author(s)
      Nhung Ngoc Hoang, Yoshiaki Kitaya, Toshio Shibuya, Ryosuke Endo
    • Journal Title

      Plant Cell, Tissue and Organ Culture

      Volume: 143 Issue: 1 Pages: 87-96

    • DOI

      10.1007/s11240-020-01898-z

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Phosphoregulation of a Conserved Herpesvirus Tegument Protein by a Virally Encoded Protein Kinase in Viral Pathogenicity and Potential Linkage between Its Evolution and Viral Phylogeny2020

    • Author(s)
      Shibazaki Misato、Kato Akihisa、Takeshima Kosuke、Ito Jumpei、Suganami Mai、Koyanagi Naoto、Maruzuru Yuhei、Sato Kei、Kawaguchi Yasushi
    • Journal Title

      Journal of Virology

      Volume: 94 Issue: 18 Pages: 1-4

    • DOI

      10.1128/jvi.01055-20

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of supporting materials in in vitro acclimatization stage on ex vitro growth of wasabi plants2020

    • Author(s)
      Hoang Nhung Ngoc、Kitaya Yoshiaki、Shibuya Toshio、Endo Ryosuke
    • Journal Title

      Scientia Horticulturae

      Volume: 261 Pages: 109042-109042

    • DOI

      10.1016/j.scienta.2019.109042

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of spaceflight on the murine thymus and mitigation by exposure to artificial gravity during spaceflight2019

    • Author(s)
      Horie Kenta、Kato Tamotsu、Kudo Takashi、Sasanuma Hiroki、Miyauchi Maki、Akiyama Nobuko、Miyao Takahisa、Seki Takao、Ishikawa Tatsuya、Takakura Yuki、Shirakawa Masaki、Shiba Dai、Hamada Michito、Jeon Hyojung、Yoshida Nobuaki、Inoue Jun-ichiro、Muratani Masafumi、Takahashi Satoru、Ohno Hiroshi、Akiyama Taishin
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 19866-19866

    • DOI

      10.1038/s41598-019-56432-9

    • NAID

      120007132915

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Biological Effects of Anti-RANKL Antibody and Zoledronic Acid on Growth and Tooth Eruption in Growing Mice2019

    • Author(s)
      Isawa M, Karakawa, Sakai N, Nishina S, Kuritani M, Chatani M, Negishi-Koga T, Sato M, Inoue M, Shimada Y, Takami M
    • Journal Title

      Sci Rep

      Volume: 9(1) Issue: 1 Pages: 19895-19895

    • DOI

      10.1038/s41598-019-56151-1

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Roles of monocarboxylate transporter subtypes in promotion and suppression of osteoclast differentiation and survival on bone.2019

    • Author(s)
      Imai H, Yoshimura K, Miyamoto Y, Sasa K, Sugano M, Chatani M, Takami M, Yamamoto M, Kamijo R
    • Journal Title

      Sci Rep

      Volume: 9 Issue: 1 Pages: 15608-15608

    • DOI

      10.1038/s41598-019-52128-2

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate.2019

    • Author(s)
      Arai HN, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, Shukunami C, Akiyama H, Kist R, Sehara-Fujisawa A.
    • Journal Title

      Cell Rep

      Volume: 29 Issue: 3 Pages: 603-616

    • DOI

      10.1016/j.celrep.2019.09.019

    • NAID

      120006731597

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A bidirectional network for appetite control in zebrafish2019

    • Author(s)
      Wee, C.L., Song, E.Y., Johnson, R.E., Ailani, D., Randlett, O., Kim, J.-Y., Nikitchenko, M., Bahl, A., Yang, C.-T., Ahrens, M.B., Kawakami, K., Engert, F., and Kunes, S.
    • Journal Title

      eLife

      Volume: 8

    • DOI

      10.7554/elife.43775

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Treatment with synthetic glucocorticoid impairs bone metabolism, as revealed by in vivo imaging of osteoblasts and osteoclasts in medaka fish2019

    • Author(s)
      Azetsu, Y., Chatani M, Dodo Y, Karakawa A, Sakai N, Negishi-Koga T, Takami M
    • Journal Title

      Biomed Pharmacother

      Volume: 118 Pages: 109101-109101

    • DOI

      10.1016/j.biopha.2019.109101

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Bone loss caused by dopaminergic degeneration and levodopa treatment in Parkinson’s disease model mice2019

    • Author(s)
      Handa Kazuaki、Kiyohara Shuichi、Yamakawa Tomoyuki、Ishikawa Koji、Hosonuma Masahiro、Sakai Nobuhiro、Karakawa Akiko、Chatani Masahiro、Tsuji Mayumi、Inagaki Katsunori、Kiuchi Yuji、Takami Masamichi、Negishi-Koga Takako
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 13768-13768

    • DOI

      10.1038/s41598-019-50336-4

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Hypergravity induces vertebrae and otolith deformation in medaka fish2019

    • Author(s)
      Chatani M, Mitsuhashi A, Dodo Y, Sakai N, and Takami M
    • Journal Title

      Biological Sciences in Space

      Volume: 33 Issue: 0 Pages: 12-17

    • DOI

      10.2187/bss.33.12

    • NAID

      130007705239

    • ISSN
      0914-9201, 1349-967X
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Male mice, caged in the International space station for 35 days, sire healthy offspring.2019

    • Author(s)
      Matsumura T, Noda T, Muratani M, Okada R, Yamane M, Isotani A, Kudo T, Takahashi S, Ikawa M.
    • Journal Title

      Scientific Research

      Volume: 9 Issue: 1 Pages: 13733-13733

    • DOI

      10.1038/s41598-019-50128-w

    • NAID

      120006957452

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mitochondrial dysfunction causes Ca2+ overload and ECM degradation?mediated muscle damage in C. elegans2019

    • Author(s)
      Sudevan Surabhi、Takiura Mai、Kubota Yukihiko、Higashitani Nahoko、Cooke Michael、Ellwood Rebecca A.、Etheridge Timothy、Szewczyk Nathaniel J.、Higashitani Atsushi
    • Journal Title

      The FASEB Journal

      Volume: 33 Issue: 8 Pages: 9540-9550

    • DOI

      10.1096/fj.201802298r

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The neuropeptide GsMTx4 inhibits a mechanosensitive BK channel through the voltage-dependent modification specific to mechano-gating.2019

    • Author(s)
      Li H, Xu J, Tang M, Shen ZS, Wang GM, Tnag M, Du XR, Lv YT, Wang JJ, Zhang FF, Qi Z, Zhang Z, Sokabe M*, Tnag QY*
    • Journal Title

      J Biol Chem

      Volume: 294 Issue: 31 Pages: 11892-11909

    • DOI

      10.1074/jbc.ra118.005511

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Neural signatures of sleep in zebrafish2019

    • Author(s)
      3.Leung, L.C., Wang, G.X., Madelaine, R., Skariah, G., Kawakami, K., Deisseroth, K., Urban, A.E., and Mourrain, P
    • Journal Title

      Nature

      Volume: 571 Issue: 7764 Pages: 198-204

    • DOI

      10.1038/s41586-019-1336-7

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] mTORC1 Activation in Osteoclasts Prevents Bone Loss in a Mouse Model of Osteoporosis.2019

    • Author(s)
      Hiraiwa M, Ozaki K, Yamada T, Iezaki T, Park G, Fukasawa K, Horie T, Kamada H, Tokumura K, Motono M, Kaneda K, Hinoi E.
    • Journal Title

      Front Pharmacol.

      Volume: 10 Pages: 00684-00684

    • DOI

      10.3389/fphar.2019.00684

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway2019

    • Author(s)
      Ozaki Kakeru、Yamada Takanori、Horie Tetsuhiro、Ishizaki Atsushi、Hiraiwa Manami、Iezaki Takashi、Park Gyujin、Fukasawa Kazuya、Kamada Hikari、Tokumura Kazuya、Motono Mei、Kaneda Katsuyuki、Ogawa Kazuma、Ochi Hiroki、Sato Shingo、Kobayashi Yasuhiro、Shi Yun-Bo、Taylor Peter M.、Hinoi Eiichi
    • Journal Title

      Science Signaling

      Volume: 12 Issue: 589 Pages: 589-589

    • DOI

      10.1126/scisignal.aaw3921

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Tensile Loads on Tethered Actin Filaments Induce Accumulation of Cell Adhesion-Associated Proteins in Vitro.2019

    • Author(s)
      Kiyoshima, D., H. Tatsumi, H. Hirata, and M. Sokabe. 2018
    • Journal Title

      Langmuir

      Volume: 印刷中 Issue: 23 Pages: 7443-7451

    • DOI

      10.1021/acs.langmuir.8b02076

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] An influenza-derived membrane tension-modulating peptide regulates cell movement and morphology via actin remodeling2019

    • Author(s)
      Masuda Toshihiro、Baba Kentarou、Nomura Takeshi、Tsujita Kazuya、Murayama Tomo、Itoh Toshiki、Takatani-Nakase Tomoka、Sokabe Masahiro、Inagaki Naoyuki、Futaki Shiroh
    • Journal Title

      Communications Biology

      Volume: 2 Issue: 1 Pages: 243-243

    • DOI

      10.1038/s42003-019-0486-3

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential‐dependent coupling with PTEN2019

    • Author(s)
      Numaga‐Tomita Takuro、Shimauchi Tsukasa、Oda Sayaka、Tanaka Tomohiro、Nishiyama Kazuhiro、Nishimura Akiyuki、Birnbaumer Lutz、Mori Yasuo、Nishida Motohiro
    • Journal Title

      The FASEB Journal

      Volume: 33 Issue: 9 Pages: 9785-9796

    • DOI

      10.1096/fj.201802811r

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Down-regulation of GATA1-dependent erythrocyte-related genes in the spleens of mice exposed to a space travel2019

    • Author(s)
      Horie Kenta、Sasanuma Hiroki、Kudo Takashi、Fujita Shin-ichiro、Miyauchi Maki、Miyao Takahisa、Seki Takao、Akiyama Nobuko、Takakura Yuki、Shimbo Miki、Jeon Hyojung、Shirakawa Masaki、Shiba Dai、Yoshida Nobuaki、Muratani Masafumi、Takahashi Satoru、Akiyama Taishin
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 444-444

    • DOI

      10.1038/s41598-019-44067-9

    • NAID

      120007133360

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] L-type calcium channel modulates mechanosensitivity of the cardiomyocyte cell line H9c22019

    • Author(s)
      Ken Takahashi, Shogo Hayashi, Mari Miyajima, Marei Omori, Jing Wang, Keiko Kaihara, Masatoshi Morimatsu, Chen Wang, Jian Chen, Gentaro Iribe, Keiji Naruse, Masahiro Sokabe
    • Journal Title

      Cell Calcium

      Volume: 79 Pages: 68-74

    • DOI

      10.1016/j.ceca.2019.02.008

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] PDH-mediated metabolic flow is critical for skeletal muscle stem cell differentiation and myotube formation during regeneration in mice2019

    • Author(s)
      Hori Shimpei、Hiramuki Yosuke、Nishimura Daigo、Sato Fuminori、Sehara-Fujisawa Atsuko
    • Journal Title

      The FASEB Journal

      Volume: - Issue: 7 Pages: 8094-8109

    • DOI

      10.1096/fj.201802479r

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Distinct modes of death in human neural stem and glioblastoma cells irradiated with carbon-ion radiation and gamma-rays2019

    • Author(s)
      Yokota Y., Wada Y., Funayama T.
    • Journal Title

      International Journal of Radiation Biology

      Volume: 96 Issue: 2 Pages: 172-178

    • DOI

      10.1080/09553002.2020.1683639

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diallyl Disulfide Mitigates DNA Damage and Spleen Tissue Effects After Irradiation2019

    • Author(s)
      Nakajima Tetsuo、Vares Guillaume、Ninomiya Yasuharu、Wang Bing、Katsube Takanori、Tanaka Kaoru、Maruyama Kouichi、Nenoi Mitsuru
    • Journal Title

      Medical Science Monitor

      Volume: 25 Pages: 8920-8927

    • DOI

      10.12659/msm.917207

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Expression Profile of Cell Cycle-Related Genes in Human Fibroblasts Exposed Simultaneously to Radiation and Simulated Microgravity2019

    • Author(s)
      Ikeda Hiroko、Muratani Masafumi、Hidema Jun、Hada Megumi、Fujiwara Keigi、Souda Hikaru、Yoshida Yukari、Takahashi Akihisa
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 19 Pages: 4791-4791

    • DOI

      10.3390/ijms20194791

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Culture independent approach reveals domination of human-oriented microbes in a pharmaceutical manufacturing facility2019

    • Author(s)
      Kawai Mako、Ichijo Tomoaki、Takahashi Yuji、Noguchi Miyako、Katayama Hirohito、Cho Otomi、Sugita Takashi、Nasu Masao
    • Journal Title

      European Journal of Pharmaceutical Sciences

      Volume: 137 Pages: 104973-104973

    • DOI

      10.1016/j.ejps.2019.104973

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap12019

    • Author(s)
      Suzuki Takafumi、Muramatsu Aki、Saito Ryota、Iso Tatsuro、Shibata Takahiro、Kuwata Keiko、Kawaguchi Shin-ichi、Iwawaki Takao、Adachi Saki、Suda Hiromi、Morita Masanobu、Uchida Koji、Baird Liam、Yamamoto Masayuki
    • Journal Title

      Cell Reports

      Volume: 28 Issue: 3 Pages: 746-758

    • DOI

      10.1016/j.celrep.2019.06.047

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Monoenergetic 290 MeV/n carbon-ion beam biological lethal dose distribution surrounding the Bragg peak2019

    • Author(s)
      Buglewicz Dylan J.、Banks Austin B.、Hirakawa Hirokazu、Fujimori Akira、Kato Takamitsu A.
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 6157-6157

    • DOI

      10.1038/s41598-019-42600-4

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effects of gravity direction on water transport in sweetpotato plants2019

    • Author(s)
      Tokuda Ayako、Kitaya Yoshiaki
    • Journal Title

      Biological Sciences in Space

      Volume: 33 Issue: 0 Pages: 18-21

    • DOI

      10.2187/bss.33.18

    • NAID

      130007756583

    • ISSN
      0914-9201, 1349-967X
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute Social Defeat Stress Increases Sleep in Mice2019

    • Author(s)
      Fujii Shinya、Kaushik Mahesh K.、Zhou Xuzhao、Korkutata Mustafa、Lazarus Michael
    • Journal Title

      Frontiers in Neuroscience

      Volume: 13 Pages: 322-322

    • DOI

      10.3389/fnins.2019.00322

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Non-canonical cholinergic anti-inflammatory pathway-mediated activation of peritoneal macrophages induces Hes1 and blocks ischemia/ reperfusion injury in the kidney.2019

    • Author(s)
      Inoue T,Abe C, Kohro T, Tanaka S, Huang L, Yao J, Zheng S, Ye H, Inagi R, Stornetta RL, Rosin DL, Nangaku M, Wada Y, Okusa MD
    • Journal Title

      Kidney International

      Volume: 95(3) Issue: 3 Pages: 563-576

    • DOI

      10.1016/j.kint.2018.09.020

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Reduction of Delayed Homologous Recombination by Induction of Radioadaptive Response in RaDR-GFP Mice (Yonezawa Effect): An Old Player with A New Role2019

    • Author(s)
      Cuihua Liu, Hirokazu Hirakawa, Kaoru Tanaka, Fazliana Mohd Saaya, Mitsuru Nenoi, Akira Fujimori, Bing Wang
    • Journal Title

      Dose-Response

      Volume: - Issue: 3 Pages: 1-10

    • DOI

      10.1177/1559325818790152

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A Small Fish Model for Quantitative Analysis of Radiation Effects Using Visualized Thymus Responses in GFP Transgenic Medaka.2019

    • Author(s)
      Maruyama K., Iwanami N., Maruyama-Hayakawa T., Doi K., Wang B.
    • Journal Title

      International Journal of Radiation Biology

      Volume: - Issue: 8 Pages: 1-16

    • DOI

      10.1080/09553002.2019.1589019

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Radiobiological Characterization of Canine Malignant Melanoma Cell Lines with Different Types of Ionizing Radiation and Efficacy Evaluation with Cytotoxic Agents2019

    • Author(s)
      Yoshikawa Hiroto、Sunada Shigeaki、Hirakawa Hirokazu、Fujimori Akira、Elmegerhi Suad、Leary Del、Kato Takamitsu
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 4 Pages: 841-841

    • DOI

      10.3390/ijms20040841

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Extracellular adenosine and slow-wave sleep are increased after ablation of nucleus accumbens core astrocytes and neurons in mice2019

    • Author(s)
      Zhou X, Oishi Y, Cherasse Y, Korkutata M, Fujii S, Lee CY, Lazarus M
    • Journal Title

      Neurochemistry International

      Volume: 124 Pages: 256-263

    • DOI

      10.1016/j.neuint.2019.01.020

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Aqueous/Aqueous Micro Phase Separation: Construction of an Artificial Model of Cellular Assembly2019

    • Author(s)
      Sakuta Hiroki、Fujimoto Tadashi、Yamana Yusuke、Hoda Yusuke、Tsumoto Kanta、Yoshikawa Kenichi
    • Journal Title

      Frontiers in Chemistry

      Volume: 7 Pages: 44-44

    • DOI

      10.3389/fchem.2019.00044

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Circumnutational movement in rice coleoptiles involves the gravitropic response: analysis of an agravitropic mutant and space-grown seedlings2019

    • Author(s)
      Kobayashi Akie、Kim Hye-Jeong、Tomita Yuta、Miyazawa Yutaka、Fujii Nobuharu、Yano Sachiko、Yamazaki Chiaki、Kamada Motoshi、Kasahara Haruo、Miyabayashi Sachiko、Shimazu Toru、Fusejima Yasuo、Takahashi Hideyuki
    • Journal Title

      Physiologia Plantarum

      Volume: 165 Issue: 3 Pages: 464-475

    • DOI

      10.1111/ppl.12824

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Progression of Peripheral Vestibular Dysfunctions in Patients With a Mitochondrial A3243G Mutation2019

    • Author(s)
      Inoue Aki、Iwasaki Shinichi、Fujimoto Chisato、Kinoshita Makoto、Yamasoba Tatsuya
    • Journal Title

      Otology & Neurotology

      Volume: 40 Issue: 3 Pages: 359-364

    • DOI

      10.1097/mao.0000000000002091

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Nucleolar protein nucleolin functions in replication stress-induced DNA damage responses2019

    • Author(s)
      Kawamura K, Qi F, Meng Q, Hayashi I, Kobayashi J.
    • Journal Title

      J Radiat Res

      Volume: - Issue: 3 Pages: 281-288

    • DOI

      10.1093/jrr/rry114

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] G9a-dependent histone methylation can be induced in G1 phase of cell cycle.2019

    • Author(s)
      Fukuda M, Sakaue-Sawano A, Shimura C, Tachibana M, Miyawaki A, Shinkai Y.
    • Journal Title

      Sci Rep.

      Volume: 9 Issue: 1 Pages: 956-956

    • DOI

      10.1038/s41598-018-37507-5

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Biophysical mechanisms of membrane thickness dependent MscL gating: An all atom molecular dynamics study2018

    • Author(s)
      Katsuta H, Sawada Y, Sokabe M
    • Journal Title

      Langmuir

      Volume: - Issue: 23 Pages: 7432-7442

    • DOI

      10.1021/acs.langmuir.8b02074

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Quantitative phosphoproteomic analysis of the molecular substrates of sleep need2018

    • Author(s)
      Z. Wang, J. Ma, C. Miyoshi, Y. Li, M Sato, Y. Ogawa, T. Lou, C. Ma, X. Gao, C. Lee, T. Fujiyama, X. Yang, S. Zhou, N. Hotta-Hirashima, D. Klewe-Nebenus, A. Ikkyu, M. Kakizaki, S. Kanno, L. Cao, S. Takahashi, J. Peng, Y. Yu, H. Funato, M. Yanagisawa, Q. Liu
    • Journal Title

      Nature

      Volume: 558 Issue: 7710 Pages: 435-439

    • DOI

      10.1038/s41586-018-0218-8

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis.2018

    • Author(s)
      Sato R, Kato A, Chimura T, Saitoh SI, Shibata T, Murakami Y, Fukui R, Liu K, Zhang Y, Arii J, Sun-Wada GH, Wada Y, Ikenoue T, Barber GN, Manabe T, Kawaguchi Y, Miyake K.
    • Journal Title

      Nat Immunol.

      Volume: 19 Issue: 10 Pages: 1071-1082

    • DOI

      10.1038/s41590-018-0203-2

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression2018

    • Author(s)
      Calcinotto A, Brevi A, Chesi M, Ferrarese R, Garcia Perez L, Grioni M, Kumar S, Garbitt VM, Sharik ME, Henderson KJ, Tonon G, Tomura M, Miwa Y, Esplugues E, Flavell RA, Huber S, Canducci F, Rajkumar VS, Bergsagel PL, Bellone M
    • Journal Title

      Nature comm

      Volume: 9 Issue: 1 Pages: 4832-4832

    • DOI

      10.1038/s41467-018-07305-8

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice.2018

    • Author(s)
      Ford MJ, Yeyati PL, Mali GR, Keighren MA, Waddell SH, Mjoseng HK, Douglas AT, Hall EA, Sakaue-Sawano A, Miyawaki A, Meehan RR, Boulter L, Jackson IJ, Mill P, Mort RL.
    • Journal Title

      Dev Cell

      Volume: 47 Issue: 4 Pages: 509-523

    • DOI

      10.1016/j.devcel.2018.10.027

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The choroid plexus is an important circadian clock component2018

    • Author(s)
      Myung Jihwan、Schmal Christoph、Hong Sungho、Tsukizawa Yoshiaki、Rose Pia、Zhang Yong、Holtzman Michael J.、De Schutter Erik、Herzel Hanspeter、Bordyugov Grigory、Takumi Toru
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 1062-1062

    • DOI

      10.1038/s41467-018-03507-2

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis.2018

    • Author(s)
      Iezaki T, Fukasawa K, Horie T, Park G, Robinson S, Nakaya M, Fujita H, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Yoneda Y, Takarada T, Guo XE, Kurose H, Hinoi E.
    • Journal Title

      Development

      Volume: 145 Pages: 164004-164004

    • DOI

      10.1242/dev.164004

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Reactive oxygen species up-regulate expression of muscle atrophy-associated ubiquitin ligase Cbl-b in rat L6 skeletal muscle cells.2018

    • Author(s)
      Yuushi Okumura et al.
    • Journal Title

      Am J Physiol Cell Physiol.

      Volume: 印刷中 Issue: 6 Pages: C721-C731

    • DOI

      10.1152/ajpcell.00184.2017

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] TRPC5-eNOS Axis Negatively Regulates ATP-Induced Cardiomyocyte Hypertrophy.2018

    • Author(s)
      Sunggip C, Shimoda K, Oda S, Tanaka T, Nishiyama K, Mangmool S, Nishimura A, Numaga-Tomita T and Nishida M
    • Journal Title

      Front. Pharmacol.

      Volume: 9 Pages: 523-523

    • DOI

      10.3389/fphar.2018.00523

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Identification of a neuronal population in the telencephalon essential for fear conditioning in zebrafish.2018

    • Author(s)
      Lal P, Tanabe H, Suster ML, Ailani D, Kotani Y, Muto A, Itoh M, Iwasaki M, Wada H, Yaksi E, Kawakami K.
    • Journal Title

      BMC Biol.

      Volume: 16 Issue: 1 Pages: 45-45

    • DOI

      10.1186/s12915-018-0502-y

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Role of C1 neurons in anti-inflammatory reflex: Mediation between afferents and efferents.2018

    • Author(s)
      Chikara Abe, Tsuyoshi Inoue
    • Journal Title

      Neuroscience Research

      Volume: 136 Pages: 6-12

    • DOI

      10.1016/j.neures.2018.05.001

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Manganese in toenails is associated with hearing loss at high frequencies in humans.2018

    • Author(s)
      Ohgami N, Li X, Yajima I, Oshino R, Ohgami K, Kato Y, Ahsan N, Akhand AA, Kato M
    • Journal Title

      Biomarkers

      Volume: 23 Issue: 6 Pages: 533-539

    • DOI

      10.1080/1354750x.2018.1458153

    • NAID

      120006536930

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Arsenic level in toenails is associated with hearing loss in humans.2018

    • Author(s)
      Li X, Ohgami N, Yajima I, Xu H, Iiida M, Ohino R, Ninomiya H, Shen D, Ahsan N, Akhand AA, Kato M
    • Journal Title

      PLoS ONE

      Volume: 13 Issue: 7 Pages: e0198743-e0198743

    • DOI

      10.1371/journal.pone.0198743

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Increased expression level of Hsp70 in the inner ears of mice by exposure to low frequency noise.2018

    • Author(s)
      Ninomiya H, Ohgami N, Oshino R, Kato M, Ohgami K, Li X, Shen D, Iida M, Yajima I, Angelidis CE, Adachi H, Katsuno M, Sobue G, Kato M.
    • Journal Title

      Hear Res

      Volume: - Pages: 49-54

    • DOI

      10.1016/j.heares.2018.02.006

    • NAID

      120006517664

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Palmitoyl ascorbic acid 2-glucoside has the potential to protect mammalian cells from high-LET carbon-ion radiation2018

    • Author(s)
      Alexis H. Haskins, Dylan J. Buglewicz, Hirakawa Hirokazu, Akira Fujimori, Yasushi Aizawa, Takamitsu A. Kato
    • Journal Title

      Scientific Reports

      Volume: 8(1) Issue: 1 Pages: 1-7

    • DOI

      10.1038/s41598-018-31747-1

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] DNA Repair Deficient Chinese Hamster Ovary Cells Exhibiting Differential Sensitivity to Charged Particle Radiation under Aerobic and Hypoxic Conditions2018

    • Author(s)
      Cartwright Ian M.、Su Cathy、Haskins Jeremy S.、Salinas Victoria A.、Sunada Shigeaki、Yu Hao、Uesaka Mitsuru、Hirakawa Hirokazu、Chen David J.、Fujimori Akira、Kato Takamitsu A.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 19 Issue: 8 Pages: 2228-2228

    • DOI

      10.3390/ijms19082228

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Apoptosis induction by iron radiation via inhibition of autophagy in Trp53+/- mouse testes: Is chronic restraint-induced stress a modifying factor?2018

    • Author(s)
      Hongyan Li, Bing Wang, Hong Zhang, Takanori Katsube, Yi Xie, Lu Gan.
    • Journal Title

      International Journal of Biological Sciences

      Volume: 14(9) Issue: 9 Pages: 1109-1121

    • DOI

      10.7150/ijbs.22805

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Enhancing endogenous adenosine A2A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function2018

    • Author(s)
      Korkutata M, Saitoh T, Cherasse Y, Ioka S, Duo F, Qin R, Murakoshi N, Fujii S, Zhou X, Sugiyama F, Chen JF, Kumagai H, Nagase H, Lazarus M
    • Journal Title

      Neuropharmacology

      Volume: 144 Pages: 122-132

    • DOI

      10.1016/j.neuropharm.2018.10.022

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Sleep and wakefulness are controlled by ventral medial midbrain/pons GABAergic neurons in mice2018

    • Author(s)
      Takata Y, Oishi Y, Zhou XZ, Hasegawa E, Takahashi K, Cherasse Y, Sakurai T, Lazarus M
    • Journal Title

      Journal of Neuroscience

      Volume: 0598-18 Issue: 47 Pages: 10080-10092

    • DOI

      10.1523/jneurosci.0598-18.2018

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A tRNA-based multiplex sgRNA expression system in zebrafish and its application to generation of transgenic albino fish2018

    • Author(s)
      Tomoya Shiraki, Koichi Kawakami
    • Journal Title

      Scientific reports

      Volume: 8 Issue: 1 Pages: 13366-13366

    • DOI

      10.1038/s41598-018-31476-5

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] FRET-based tension measurement across actin-associated mechanotransductive structures using Lima12018

    • Author(s)
      Hirano S, Yamamoto T, Michiue T
    • Journal Title

      Int. J. Dev. Biol.

      Volume: 62 Issue: 9-10 Pages: 631-636

    • DOI

      10.1387/ijdb.180110tm

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Integrin β1 activity is required for cardiovascular formation in zebrafish.2018

    • Author(s)
      Iida A, Wang Z, Hirata H, Sehara-Fujisawa A
    • Journal Title

      Genes to Cells

      Volume: 23 Issue: 11 Pages: 938-951

    • DOI

      10.1111/gtc.12641

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nematode Muscles Project in Spaceflight Experiment2018

    • Author(s)
      Surabhi Sudevan, Toko Hashizume, Sachiko Yano, Kana Kuriyama, Kenta Momma, Shunsuke Harada, Masumi Umehara, Akira Higashibata, Atsushi Higashitani
    • Journal Title

      Biological Sciences in Space

      Volume: 32 Issue: 0 Pages: 6-10

    • DOI

      10.2187/bss.32.6

    • NAID

      130007430368

    • ISSN
      0914-9201, 1349-967X
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis.2018

    • Author(s)
      Iezaki T, Horie T, Fukasawa K, Kitabatake M, Nakamura Y, Park G, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Manabe T, Ishigaki Y, Ohno M, Hinoi E.
    • Journal Title

      Stem Cell Reports

      Volume: 11 Issue: 1 Pages: 228-241

    • DOI

      10.1016/j.stemcr.2018.05.020

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Specific Spatial Localization of Actin and DNA in a?Water/Water Microdroplet: Self-Emergence of a Cell-Like Structure2018

    • Author(s)
      Nakatani Naoki、Sakuta Hiroki、Hayashi Masahito、Tanaka Shunsuke、Takiguchi Kingo、Tsumoto Kanta、Yoshikawa Kenichi
    • Journal Title

      ChemBioChem

      Volume: 19 Issue: 13 Pages: 1370-1374

    • DOI

      10.1002/cbic.201800066

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Protocadherin-Mediated Cell Repulsion Controls the Central Topography and Efferent Projections of the Abducens Nucleus2018

    • Author(s)
      Kazuhide Asakawa, Koichi Kawakami
    • Journal Title

      Cell reports

      Volume: 576:00:00 Issue: 6 Pages: 1562-1572

    • DOI

      10.1016/j.celrep.2018.07.024

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Long-term hindlimb unloading causes a preferential reduction of medullary thymic epithelial cells expressing autoimmune regulator (Aire).2018

    • Author(s)
      Horie K, Kudo T, Yoshinaga R, Akiyama N, Sasanuma H, Kobayashi TJ, Shimbo M, Jeon H, Miyao T, Miyauchi M, Shirakawa M, Shiba D, Yoshida N, Muratani M, Takahashi S, Akiyama T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 501 Pages: 754-750

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Anti-mouse RANKL Antibodies Inhibit Alveolar Bone Destruction in Periodontitis Model Mice2018

    • Author(s)
      Kuritani M, Sakai N, Karakawa A, Isawa M, Chatani M, Negishi-Koga T, Funatsu T, Takami M.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 41 Issue: 4 Pages: 637-643

    • DOI

      10.1248/bpb.b18-00026

    • NAID

      130006602562

    • ISSN
      0918-6158, 1347-5215
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Aging Is a Risk Factor for Utricular Dysfunction in Idiopathic Benign Paroxysmal Positional Vertigo2018

    • Author(s)
      Fujimoto Chisato、Kawahara Takuya、Kinoshita Makoto、Kikkawa Yayoi S.、Sugasawa Keiko、Yagi Masato、Yamasoba Tatsuya、Iwasaki Shinichi、Murofushi Toshihisa
    • Journal Title

      Frontiers in Neurology

      Volume: 9 Pages: 1049-1049

    • DOI

      10.3389/fneur.2018.01049

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dynamic cerebral autoregulation after confinement in an isolated environment for 14 days2018

    • Author(s)
      Tomokazu Kato, Ryo Yanagida, Chiharu Takko, Takuya Kurazumi, Natsuhiko Inoue, Go Suzuki, Yojiro Ogawa, Satoshi Furukawa, Ken-ichi Iwasaki
    • Journal Title

      Environmental Health and Preventive Medicine

      Volume: 23 Issue: 1 Pages: 61-61

    • DOI

      10.1186/s12199-018-0751-y

    • NAID

      210000130314

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Improvement of balance in young adults by a sound component at 100 Hz in music2018

    • Author(s)
      Xu H, Ohgami N, He T, Hashimoto K, Tazaki, A, Ohgami K, Takeda K, Kato M
    • Journal Title

      Scientific Reports

      Volume: 8(1) Issue: 1 Pages: 16894-16894

    • DOI

      10.1038/s41598-018-35244-3

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Noisy Galvanic Vestibular Stimulation Sustainably Improves Posture in Bilateral Vestibulopathy2018

    • Author(s)
      Fujimoto Chisato、Egami Naoya、Kawahara Takuya、Uemura Yukari、Yamamoto Yoshiharu、Yamasoba Tatsuya、Iwasaki Shinichi
    • Journal Title

      Frontiers in Neurology

      Volume: 9 Pages: 900-900

    • DOI

      10.3389/fneur.2018.00900

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A disadvantageous effect of adsorption of barium by melanin on transforming activity.2018

    • Author(s)
      Omata Y, Yoshinaga M, Yajima I, Ohgami N, Hashimoto K, Higashimura K, Tazaki A, Kato M
    • Journal Title

      Chemosphere

      Volume: 210 Pages: 384-391

    • DOI

      10.1016/j.chemosphere.2018.07.022

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Plasminogen activator inhibitor-1 deficiency suppresses osteoblastic differentiation of mesenchymal stem cells in mice.2018

    • Author(s)
      Takafuji Y, Tatsumi K, Ishida M, Kawao N, Okada K, Matsuo O, Kaji H.
    • Journal Title

      J Cell Physiol.

      Volume: 234 Issue: 6 Pages: 9687-9697

    • DOI

      10.1002/jcp.27655

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The circulating immunoglobulins negatively impact on the parasite clearance in the liver of Leishmania donovani-infected mice via dampening ROS activity2018

    • Author(s)
      Srinontong Piyarat、Wu Zhiliang、Sato Katsuya、Nagaoka Hitoshi、Maekawa Yoichi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 506 Issue: 1 Pages: 20-26

    • DOI

      10.1016/j.bbrc.2018.10.055

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Amount of daily exercise is an essential stimulation to alter the epigenome of skeletal muscle in rats.2018

    • Author(s)
      Ohsawa I, Konno R, Masuzawa R, and Kawano F
    • Journal Title

      Journal of Applied Physiology

      Volume: 125 Issue: 4 Pages: 1097-1104

    • DOI

      10.1152/japplphysiol.00074.2018

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Muscle type-specific RNA polymerase II recruitment during PGC-1α gene transcription after acute exercise in adult rats.2018

    • Author(s)
      Masuzawa R, Konno R, Ohsawa I. Watanabe A, and Kawano F
    • Journal Title

      Journal of Applied Physiology

      Volume: 125 Issue: 4 Pages: 1238-1245

    • DOI

      10.1152/japplphysiol.00202.2018

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Serpina3n, dominantly expressed in female osteoblasts, suppresses the phenotypes of differentiated osteoblasts in mice.2018

    • Author(s)
      Ishida M, Kawao N, Okada K, Tatsumi K, Sakai K, Nishio K, Kaji H.
    • Journal Title

      Endocrinology

      Volume: 159 Pages: 3775-3790

    • DOI

      10.1210/en.2018-00639

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The effect of mild decrement in plasma volume simulating short-duration spaceflight on intracranial pressure2018

    • Author(s)
      Takuya Kurazumi, Yojiro Ogawa, Hiroshi Morisaki, Ken-ichi Iwasaki
    • Journal Title

      npj Microgravity

      Volume: 4 Issue: 1

    • DOI

      10.1038/s41526-018-0053-0

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Plasminogen activator inhibitor-1 is involved in interleukin-1β-induced matrix metalloproteinase expression in murine chondrocytes.2018

    • Author(s)
      Moritake A, Kawao N, Okada K, Ishida M, Tatsumi K, Matsuo O, Akagi M, Kaji H.
    • Journal Title

      Mod Rheumatol

      Volume: 28 Issue: 6 Pages: 1-5

    • DOI

      10.1080/14397595.2018.1525018

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Time-Dependent Changes in Cerebral Blood Flow and Arterial Pressure During Mild +Gz Hypergravity2018

    • Author(s)
      Toru Konishi, Takuya Kurazumi, Tomokazu Kato, Chiharu Takko, Yojiro Ogawa, Ken-ichi Iwasaki
    • Journal Title

      Aerospace Medicine and Human Performance

      Volume: 87:5 Issue: 9 Pages: 787-791

    • DOI

      10.3357/amhp.5106.2018

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ablation of Central Serotonergic Neurons Decreased REM Sleep and Attenuated Arousal Response2018

    • Author(s)
      Iwasaki Kanako、Komiya Haruna、Kakizaki Miyo、Miyoshi Chika、Abe Manabu、Sakimura Kenji、Funato Hiromasa、Yanagisawa Masashi
    • Journal Title

      Frontiers in Neuroscience

      Volume: 12 Pages: 535-535

    • DOI

      10.3389/fnins.2018.00535

    • NAID

      120007133025

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Noisy vestibular stimulation increases gait speed in normals and in bilateral vestibulopathy2018

    • Author(s)
      Iwasaki Shinichi、Fujimoto Chisato、Egami Naoya、Kinoshita Makoto、Togo Fumiharu、Yamamoto Yoshiharu、Yamasoba Tatsuya
    • Journal Title

      Brain Stimulation

      Volume: - Issue: 4 Pages: 709-715

    • DOI

      10.1016/j.brs.2018.03.005

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Forebrain Ptf1a is required for sexual differentiation of the brain2018

    • Author(s)
      T Fujiyama, S Miyashita, Y Tsuneoka, K Kanemaru, M Kakizaki, S Kanno, Y Ishikawa, M Yamashita, T Owa, M Nagaoka, Y Kawaguchi, Y Yanagawa, M A. Magnuson, A Shibuya, Y Nabeshima, M Yanagisawa, H Funato*, M Hoshino*
    • Journal Title

      Cell Reports

      Volume: 24 Issue: 1 Pages: 79-94

    • DOI

      10.1016/j.celrep.2018.06.010

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Meal rich in rapeseed oil increases 24-h fat oxidation more than meal rich in palm oil2018

    • Author(s)
      Katsuhiko Yajima, Kaito Iwayama, Hitomi Ogata, Insung Park, Kumpei Tokuyama
    • Journal Title

      PLoS One

      Volume: 13 Issue: 6 Pages: e0198858-e0198858

    • DOI

      10.1371/journal.pone.0198858

    • NAID

      120007134017

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Immunolocalization of muscarinic M1 receptor in the rat medial prefrontal cortex2018

    • Author(s)
      Oda Satoko、Tsuneoka Yousuke、Yoshida Sachine、Adachi-Akahane Satomi、Ito Masanori、Kuroda Masaru、Funato Hiromasa
    • Journal Title

      Journal of Comparative Neurology

      Volume: 526 Issue: 8 Pages: 1329-1350

    • DOI

      10.1002/cne.24409

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Sleep disorder risk factors among student athletes2018

    • Author(s)
      Monma T, Ando A, Asanuma T, Yoshitake Y, Yoshida G, Miyazawa T, Ebine N, Takeda S, Omi N, Satoh M, Tokuyama K, Takeda F.
    • Journal Title

      Sleep Med

      Volume: 44 Pages: 76-81

    • DOI

      10.1016/j.sleep.2017.11.1130

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Synthesis of novel 1,3-dioxa-5-thiazatriquinane and 1-oxa-3,5-dithiazatriquinane derivatives and their pharmacologies2018

    • Author(s)
      Ohshita R, Kutsumura N, and Nagase H, et al
    • Journal Title

      Heterocycles

      Volume: 97 Issue: 2 Pages: 687-695

    • DOI

      10.3987/com-18-s(t)40

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Non-invasive intracranial pressure estimation during combined exposure to CO2 and head-down tilt.2018

    • Author(s)
      Kurazumi T., Ogawa Y., Yanagida R., Morisaki H., Iwasaki K.
    • Journal Title

      Aerosp Med Hum Perform.

      Volume: 89 Issue: 4 Pages: 365-370

    • DOI

      10.3357/amhp.5015.2018

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of Macrophages and Plasminogen Activator Inhibitor-1 in Delayed Bone Repair in Diabetic Female Mice2018

    • Author(s)
      Shimoide Takeshi、Kawao Naoyuki、Tamura Yukinori、Okada Kiyotaka、Horiuchi Yoshitaka、Okumoto Katsumi、Kurashimo Shinji、Ishida Masayoshi、Tatsumi Kohei、Matsuo Osamu、Kaji Hiroshi
    • Journal Title

      Endocrinology

      Volume: 159 Issue: 4 Pages: 1875-1885

    • DOI

      10.1210/en.2018-00085

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Increased Chromosome Aberrations in Cells Exposed Simultaneously to Simulated Microgravity and Radiation.2018

    • Author(s)
      Hada M, Ikeda H, Rhone JR, Beitman AJ, Plante I, Souda H, Yoshida Y, Held KD, Fujiwara K, Saganti PB, Takahashi A.
    • Journal Title

      Int J Mol Sci.

      Volume: 20 Issue: 1 Pages: 43-43

    • DOI

      10.3390/ijms20010043

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Temporary Loading Prevents Cancer Progression and Immune Organ Atrophy Induced by Hind-Limb Unloading in Mice.2018

    • Author(s)
      Takahashi A, Wakihata S, Ma L, Adachi T, Hirose H, Yoshida Y, Ohira Y.
    • Journal Title

      Int J Mol Sci.

      Volume: 19 Issue: 12 Pages: 3959-3959

    • DOI

      10.3390/ijms19123959

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Albatross/FBF1 contributes to both centriole duplication and centrosome separation2018

    • Author(s)
      Akihito Inoko, Tomoki Yano, Tatsuo Miyamoto, Shinya Matsuura, Tohru Kiyono, Naoki Goshima, Masaki Inagaki, Yuko Hayashi
    • Journal Title

      Genes to Cells

      Volume: 23 Issue: 12 Pages: 1023-1042

    • DOI

      10.1111/gtc.12648

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Selective Elimination of Membrane-Damaged Chloroplasts via Microautophagy2018

    • Author(s)
      Sakuya Nakamura, Jun Hidema, Wataru Sakamoto, Hiroyuki Ishida, Masanori Izumi
    • Journal Title

      Plant Physiology

      Volume: 177 Issue: 3 Pages: 1007-1026

    • DOI

      10.1104/pp.18.00444

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cell behavior of the highly sticky bacterium Acinetobacter sp. Tol 5 during adhesion in laminar flows2018

    • Author(s)
      Yoshihide Furuichi, Keita Iwasaki, Katsutoshi Hori
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 8285-8285

    • DOI

      10.1038/s41598-018-26699-5

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Development of a simple thermal method for measuring sap flow in plants for space experiments2018

    • Author(s)
      A. Tokuda, Y. Kitaya, H. Hirai,
    • Journal Title

      Biological Sciences in Space

      Volume: 32 Issue: 0 Pages: 17-21

    • DOI

      10.2187/bss.32.17

    • NAID

      130007543443

    • ISSN
      0914-9201, 1349-967X
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Possibility of co-culturing Euglena gracilis and Lactuca sativa L. with biogas digestate2018

    • Author(s)
      K. Takemura, R. Endo and Y. Kitaya
    • Journal Title

      Environmental Technology

      Volume: 39 Issue: 8 Pages: 1007-1014

    • DOI

      10.1080/09593330.2018.1516803

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Roles of the Phosphorylation of Herpes Simplex Virus 1 UL51 at a Specific Site in Viral Replication and Pathogenicity.2018

    • Author(s)
      Kato A, Oda S, Watanabe M, Oyama M, Kozuka-Hata H, Koyanagi N, Maruzuru Y, Arii J, Kawaguchi Y.
    • Journal Title

      J Virol.

      Volume: 92 Issue: 18

    • DOI

      10.1128/jvi.01035-18

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of Gravity on Stem Sap Flow and Water and Heat Exchange in the Leaves of Sweetpotato2018

    • Author(s)
      A. Tokuda, Y. Kitaya, H. Hirai, H. Hashimoto and Y. Inatomi
    • Journal Title

      Int. J. Microgravity Sci. Appl

      Volume: 35(3)

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Optical clearing of the pancreas for visualization of mature β-cells and vessels in mice.2018

    • Author(s)
      Nishimura W, Sakaue-Sawano A, Takahashi S, Miyawaki A, Yasuda K, Noda Y.
    • Journal Title

      Islets

      Volume: 10 Issue: 3 Pages: 106-112

    • DOI

      10.1080/19382014.2018.1451282

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oxysterol-binding protein-related protein (ORP) 6 localizes to the ER and ER-plasma membrane contact sites and is involved in the turnover of PI4P in cerebellar granule neurons.2018

    • Author(s)
      Mochizuki S, Miki H, Zhou R, Kido Y, Nishimura W, Kikuchi M, Noda Y.
    • Journal Title

      Exp Cell Res

      Volume: 370 Issue: 2 Pages: 601-612

    • DOI

      10.1016/j.yexcr.2018.07.025

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Genome-wide profiling of histone H3K27 acetylation featured fatty acid signalling in pancreatic beta cells in diet-induced obesity in mice.2018

    • Author(s)
      Nammo T, Udagawa H, Funahashi N, Kawaguchi M, Uebanso T, Hiramoto M, Nishimura W, Yasuda K.
    • Journal Title

      Diabetologia

      Volume: 61 Issue: 12 Pages: 2608-2620

    • DOI

      10.1007/s00125-018-4735-7

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Novel iRFP-incorporated in vivo murine atherosclerosis imaging system.2018

    • Author(s)
      Kulathunga K, Hamada M, Hiraishi Y, Otake M, Tran MTN, Cheng O, Tanaka J, Sakasai T, Sakaguchi S, Sugiyama Y, Fleischmann BK, Takahashi S, Miwa Y
    • Journal Title

      Sci Rep

      Volume: 8 Issue: 1 Pages: 14515-14515

    • DOI

      10.1038/s41598-018-32456-5

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] HIF-1 maintains a functional relationship between pancreatic cancer cells and stromal fibroblasts by upregulating expression and secretion of Sonic hedgehog2018

    • Author(s)
      Katagiri Tomohiro、Kobayashi Minoru、Yoshimura Michio、Morinibu Akiyo、Itasaka Satoshi、Hiraoka Masahiro、Harada Hiroshi
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 12 Pages: 10525-10535

    • DOI

      10.18632/oncotarget.24156

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Role of follistatin in muscle and bone alterations induced by gravity change in mice.2018

    • Author(s)
      Kawao N, Morita H, Obata K, Tatsumi K, Kaji H.
    • Journal Title

      J Cell Physiol.

      Volume: 233 Issue: 2 Pages: 1191-1201

    • DOI

      10.1002/jcp.25986

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regulatory mechanisms of hypoxia-inducible factor 1 activity: Two decades of knowledge2018

    • Author(s)
      Koyasu Sho、Kobayashi Minoru、Goto Yoko、Hiraoka Masahiro、Harada Hiroshi
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 3 Pages: 560-571

    • DOI

      10.1111/cas.13483

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Clinical features of otolith organ-specific vestibular dysfunction2018

    • Author(s)
      Fujimoto Chisato、Suzuki Sayaka、Kinoshita Makoto、Egami Naoya、Sugasawa Keiko、Iwasaki Shinichi
    • Journal Title

      Clinical Neurophysiology

      Volume: 129 Issue: 1 Pages: 238-245

    • DOI

      10.1016/j.clinph.2017.11.006

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Subclinical maternal depressive symptoms modulate right inferior frontal response to inferring affective mental states of adults but not of infants2018

    • Author(s)
      Shimada K, Kasaba R, Fujisawa TX, Sakakibara N, Takiguchi S, Tomoda A
    • Journal Title

      Journal of Affective Disorders

      Volume: 229 Pages: 32-40

    • DOI

      10.1016/j.jad.2017.12.031

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Roles of Irisin in the Linkage from Muscle to Bone During Mechanical Unloading in Mice2018

    • Author(s)
      Kawao Naoyuki、Moritake Akihiro、Tatsumi Kohei、Kaji Hiroshi
    • Journal Title

      Calcified Tissue International

      Volume: ? Issue: 1 Pages: 24-34

    • DOI

      10.1007/s00223-018-0387-3

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison among ultrasonic, electrical apparatus, and toxic chemicals for vestibular lesion in mice2018

    • Author(s)
      Yamaoka Yusuke、Abe Chikara、Morita Hironobu
    • Journal Title

      Journal of Neuroscience Methods

      Volume: 295 Pages: 58-67

    • DOI

      10.1016/j.jneumeth.2017.11.021

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Increased oxytocin-monomeric red fluorescent protein 1 fluorescent intensity with urocortin-like immunoreactivity in the hypothalamo-neurohypophysial system of aged transgenic rats2018

    • Author(s)
      Ohno Shigeo、Hashimoto Hirofumi、Fujihara Hiroaki、Fujiki Nobuhiro、Yoshimura Mitsuhiro、Maruyama Takashi、Motojima Yasuhito、Saito Reiko、Ueno Hiromichi、Sonoda Satomi、Ohno Motoko、Umezu Yuichi、Hamamura Akinori、Saeki Satoru、Ueta Yoichi
    • Journal Title

      Neuroscience Research

      Volume: 128 Pages: 40-49

    • DOI

      10.1016/j.neures.2017.08.001

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Encoding seasonal information in a two‐oscillator model of the multi‐oscillator circadian clock2017

    • Author(s)
      Jihwan Myung, Scott D Pauls
    • Journal Title

      European Journal of Neuroscience

      Volume: In press Issue: 8 Pages: 1-10

    • DOI

      10.1111/ejn.13697

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle2017

    • Author(s)
      Sakaue-Sawano Asako、Yo Masahiro、Komatsu Naoki、Hiratsuka Toru、Kogure Takako、Hoshida Tetsushi、Goshima Naoki、Matsuda Michiyuki、Miyoshi Hiroyuki、Miyawaki Atsushi
    • Journal Title

      Molecular Cell

      Volume: 68 Issue: 3 Pages: 626-640

    • DOI

      10.1016/j.molcel.2017.10.001

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activation of the hypothalamic feeding centre upon visual prey detection2017

    • Author(s)
      Muto Akira、Lal Pradeep、Ailani Deepak、Abe Gembu、Itoh Mari、Kawakami Koichi
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 15029-15029

    • DOI

      10.1038/ncomms15029

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice2017

    • Author(s)
      Oishi Yo、Xu Qi、Wang Lu、Zhang Bin-Jia、Takahashi Koji、Takata Yohko、Luo Yan-Jia、Cherasse Yoan、Schiffmann Serge N.、de Kerchove d’Exaerde Alban、Urade Yoshihiro、Qu Wei-Min、Huang Zhi-Li、Lazarus Michael
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 1-12

    • DOI

      10.1038/s41467-017-00781-4

    • NAID

      120007134733

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Comparative genomics of the tardigrades Hypsibius dujardini and Ramazzottius varieornatus2017

    • Author(s)
      Yoshida Yuki、Koutsovoulos Georgios、Laetsch Dominik R.、Stevens Lewis、Kumar Sujai、Horikawa Daiki D.、Ishino Kyoko、Komine Shiori、Kunieda Takekazu、Tomita Masaru、Blaxter Mark、Arakawa Kazuharu
    • Journal Title

      PLOS Biology

      Volume: 15 Issue: 7 Pages: e2002266-e2002266

    • DOI

      10.1371/journal.pbio.2002266

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A novel perivascular cell population in the zebrafish brain2017

    • Author(s)
      Galanternik Marina Venero、Castranova Daniel、Gore Aniket V、Blewett Nathan H、Jung Hyun Min、Stratman Amber N、Kirby Martha R、Iben James、Miller Mayumi F、Kawakami Koichi、Maraia Richard J、Weinstein Brant M
    • Journal Title

      eLife

      Volume: 6

    • DOI

      10.7554/elife.24369

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Moran’s I quantifies spatio-temporal pattern formation in neural imaging data2017

    • Author(s)
      Schmal Christoph、Myung Jihwan、Herzel Hanspeter、Bordyugov Grigory
    • Journal Title

      Bioinformatics

      Volume: 33 Issue: 19 Pages: 3072-3079

    • DOI

      10.1093/bioinformatics/btx351

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Arsenic-mediated hyperpigmented skin via NF-kappa B/Endothelin1 signaling in an originally developed hairless mouse model.2017

    • Author(s)
      Yajima I, Kumasaka MY, Iida M, Osino R, Tanihata H, Al Hossain A MM, Ohgami N, Kato M.
    • Journal Title

      Arch Toxicol

      Volume: 91 Issue: 11 Pages: 3507-16

    • DOI

      10.1007/s00204-017-1975-0

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The emerging roles of the ubiquitination/deubiquitination system in tumor radioresistance regarding DNA damage responses, cell cycle regulation, hypoxic responses, and antioxidant properties: Insight into the development of novel radiosensitizing strategies2017

    • Author(s)
      Goto Yoko、Koyasu Sho、Kobayashi Minoru、Harada Hiroshi
    • Journal Title

      Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

      Volume: 803-805 Pages: 76-81

    • DOI

      10.1016/j.mrfmmm.2017.07.007

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neurotransmitters and neuropeptides in gonadal steroid receptor-expressing cells in medial preoptic area subregions of the male mouse2017

    • Author(s)
      Tsuneoka Yousuke、Yoshida Sachine、Takase Kenkichi、Oda Satoko、Kuroda Masaru、Funato Hiromasa
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 1-16

    • DOI

      10.1038/s41598-017-10213-4

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Nuclear factor (erythroid derived 2)-like 2 activator increases exercise endurance capability via redox-modulation of skeletal muscles.2017

    • Author(s)
      Oh S, Komine S, Warabi E, Akiyama K, Ishii A, Ishige K, Mizokami Y, Kuga K, Horie M, Miwa Y, Iwawaki T, Yamamoto M, Shoda J
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 12902-12902

    • DOI

      10.1038/s41598-017-12926-y

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Activation of endogenous arginine vasopressin neurons inhibit food intake: by using a novel transgenic rat line with DREADDs system2017

    • Author(s)
      Yoshimura Mitsuhiro、Nishimura Kazuaki、Nishimura Haruki、Sonoda Satomi、Ueno Hiromichi、Motojima Yasuhito、Saito Reiko、Maruyama Takashi、Nonaka Yuki、Ueta Yoichi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 15728-15728

    • DOI

      10.1038/s41598-017-16049-2

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Oral exposure to arsenic causes hearing loss in young people aged 12-29 years and in young mice.2017

    • Author(s)
      Li X, Ohgami N, Omata Y, Yajima I, Iida M, Oshino R, Ohnuma S, Ahsan N, Akhand AA, Kato M.
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 6844-6844

    • DOI

      10.1038/s41598-017-06096-0

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization2017

    • Author(s)
      Nakashima Ryota、Goto Yoko、Koyasu Sho、Kobayashi Minoru、Morinibu Akiyo、Yoshimura Michio、Hiraoka Masahiro、Hammond Ester M.、Harada Hiroshi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 6879-6879

    • DOI

      10.1038/s41598-017-06605-1

    • NAID

      120006355750

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Sleep/Wake Behaviors in Mice During Pregnancy and Pregnancy-Associated Hypertensive Mice2017

    • Author(s)
      Komiya Haruna、Miyoshi Chika、Iwasaki Kanako、Hotta-Hirashima Noriko、Ikkyu Aya、Kanno Satomi、Honda Takato、Gosho Masahiko、Hamada Hiromi、Satoh Toyomi、Fukamizu Akiyoshi、Funato Hiromasa、Yanagisawa Masashi
    • Journal Title

      Sleep

      Volume: 41 Issue: 3 Pages: 1-1

    • DOI

      10.1093/sleep/zsx209

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Heat-Induced Calcium Leakage Causes Mitochondrial Damage inCaenorhabditis elegansBody-Wall Muscles2017

    • Author(s)
      Momma Kenta、Homma Takashi、Isaka Ruri、Sudevan Surabhi、Higashitani Atsushi
    • Journal Title

      Genetics

      Volume: 206 Issue: 4 Pages: 1985-1994

    • DOI

      10.1534/genetics.117.202747

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cryptoendolithic Antarctic Black Fungus Cryomyces antarcticus Irradiated with2017

    • Author(s)
      Claudia Pacelli, Ralf Moeller, Akira Fujimori et al.
    • Journal Title

      Frontiers in Microbiology

      Volume: 8 Pages: 2002-2002

    • DOI

      10.3389/fmicb.2017.02002

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A circadian clock gene, PER2, activates HIF-1 as an effector molecule for recruitment of HIF-1α to promoter regions of its downstream genes2017

    • Author(s)
      Kobayashi Minoru、Morinibu Akiyo、Koyasu Sho、Goto Yoko、Hiraoka Masahiro、Harada Hiroshi
    • Journal Title

      The FEBS Journal

      Volume: 284 Issue: 22 Pages: 3804-3816

    • DOI

      10.1111/febs.14280

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Growth responses of wasabi plantlets under different temperature regimes during photoautotrophic micropropagation2017

    • Author(s)
      Hoang NN, Kitaya Y, Endo R et al.
    • Journal Title

      Eco-Engineering

      Volume: 29(4) Pages: 125-129

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Running training experience attenuates disuse atrophy in fast-twitch skeletal muscles of rats2017

    • Author(s)
      Nakamura Keisuke、Ohsawa Ikumi、Masuzawa Ryo、Konno Ryotaro、Watanabe Atsuya、Kawano Fuminori
    • Journal Title

      Journal of Applied Physiology

      Volume: 123 Issue: 4 Pages: 902-913

    • DOI

      10.1152/japplphysiol.00289.2017

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Exposure to diphtheria toxin during the juvenile period impairs both inner and outer hair cells in C57BL/6 mice2017

    • Author(s)
      Konishi H, Ohgami N, Matsushita A, Kondo Y, Aoyama Y, Kobayashi M, Nagai T, Ugawa S, Yamada K, Kato M, Kiyama H
    • Journal Title

      Neuroscience

      Volume: 印刷中 Pages: 15-23

    • DOI

      10.1016/j.neuroscience.2017.03.028

    • NAID

      120006331816

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Upregulation of matrix metalloproteinase triggers transdifferentiation of retinal pigmented epithelial cells in Xenopus laevis: A Link between inflammatory response and regeneration2017

    • Author(s)
      Naitoh Hanako、Suganuma Yukari、Ueda Yoko、Sato Takahiko、Hiramuki Yosuke、Fujisawa-Sehara Atsuko、Taketani Shigeru、Araki Masasuke
    • Journal Title

      Developmental Neurobiology

      Volume: 77 Issue: 9 Pages: 1086-1100

    • DOI

      10.1002/dneu.22497

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Manganese-mediated decrease in levels of c-RET and tyrosine hydroxylase expression in vitro.2017

    • Author(s)
      Kumasaka MY, Yajima I, Ohgami N, Ninomiya H, Iida M, Li X, Oshino R, Tanihata H, Yoshinaga M, Kato M.
    • Journal Title

      Neurotox Res

      Volume: 32 Issue: 4 Pages: 661-70

    • DOI

      10.1007/s12640-017-9783-0

    • NAID

      120006367974

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Essential structure of orexin 1 receptor antagonist YNT-707, Part I: Role of the 4,5-epoxy ring for binding with orexin 1 receptor2017

    • Author(s)
      Yamamoto Naoshi、Ohrui Sayaka、Okada Takahiro、Yata Masahiro、Saitoh Tsuyoshi、Kutsumura Noriki、Nagumo Yasuyuki、Irukayama-Tomobe Yoko、Ogawa Yasuhiro、Ishikawa Yukiko、Watanabe Yurie、Hayakawa Daichi、Gouda Hiroaki、Yanagisawa Masashi、Nagase Hiroshi
    • Journal Title

      Bioorg Med Chem Lett.

      Volume: 27 Issue: 17 Pages: 4176-4179

    • DOI

      10.1016/j.bmcl.2017.07.011

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effects of hypergravity on gene levels in anti-gravity muscle and bone through the vestibular system in mice.2017

    • Author(s)
      Kawao N, Morita H, Nishida K, Obata K, Tatsumi K, Kaji H.
    • Journal Title

      J Physiol Sci.

      Volume: - Issue: 5 Pages: 609-616

    • DOI

      10.1007/s12576-017-0566-4

    • NAID

      40021645358

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low- and High-LET Ionizing Radiation Induces Delayed Homologous Recombination that Persists for Two Weeks before Resolving2017

    • Author(s)
      Allen Christopher P.、Hirakawa Hirokazu、Nakajima Nakako Izumi、Moore Sophia、Nie Jingyi、Sharma Neelam、Sugiura Mayumi、Hoki Yuko、Araki Ryoko、Abe Masumi、Okayasu Ryuichi、Fujimori Akira、Nickoloff Jac A.
    • Journal Title

      Radiation Research

      Volume: 188 Issue: 1 Pages: 82-93

    • DOI

      10.1667/rr14748.1

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Radiation Exposure Enhances Hepatocyte Proliferation in Neonatal Mice but not in Adult Mice2017

    • Author(s)
      Shang Yi、Sawa Yurika、Blyth Benjamin J.、Tsuruoka Chizuru、Nogawa Hiroyuki、Shimada Yoshiya、Kakinuma Shizuko
    • Journal Title

      Radiation Research

      Volume: 188 Issue: 2 Pages: 235-241

    • DOI

      10.1667/rr14563.1

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Antiangiogenic agent sunitinib induces epithelial to mesenchymal transition and accelerates motility of colorectal cancer cells2017

    • Author(s)
      Chisato Tomida, Naoko Yamagishi, Hikaru Nagano, Takayuki Uchida, Ayako Ohno, Katsuya Hirasaka, Takeshi Nikawa, Shigetada Teshima-Kondo
    • Journal Title

      The Journal of Medical Investigation

      Volume: 64 Issue: 3.4 Pages: 250-254

    • DOI

      10.2152/jmi.64.250

    • NAID

      130006105181

    • ISSN
      1343-1420, 1349-6867
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Regorafenib induces adaptive resistance of colorectal cancer cells via inhibition of vascular endothelial growth factor receptor2017

    • Author(s)
      Tomida Chisato、Nagano Hikaru、Yamagishi Naoko、Uchida Takayuki、Ohno Ayako、Hirasaka Katsuya、Nikawa Takeshi、Teshima-Kondo Shigetada
    • Journal Title

      The Journal of Medical Investigation

      Volume: 64 Issue: 3.4 Pages: 262-265

    • DOI

      10.2152/jmi.64.262

    • NAID

      130006105177

    • ISSN
      1343-1420, 1349-6867
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Oxygen Enhancement Ratio in Radiation-Induced Initial DSBs by an Optimized Flow Cytometry-based Gamma-H2AX Analysis in A549 Human Cancer Cells2017

    • Author(s)
      Sunada Shigeaki、Hirakawa Hirokazu、Fujimori Akira、Uesaka Mitsuru、Okayasu Ryuichi
    • Journal Title

      Radiation Research

      Volume: 188 Issue: 5 Pages: 671-674

    • DOI

      10.1667/rr14824.1

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Investigation of the relative biological effectiveness and uniform isobiological killing effects of irradiation with a clinical carbon SOBP beam on DNA repair deficient CHO cells2017

    • Author(s)
      Sunada Shigeaki、Cartwright Ian M.、Hirakawa Hirokazu、Fujimori Akira、Uesaka Mitsuru、Kato Takamitsu A.
    • Journal Title

      Oncology Letters

      Volume: 13 Issue: 6 Pages: 4911-4916

    • DOI

      10.3892/ol.2017.6072

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Simple generation of hairless mice for <i>in vivo</i> imaging2017

    • Author(s)
      Hoshino Y, Mizuno S, Kato K, Mizuno-Iijima S, Tanimoto Y, Ishida M, Kajiwara N, Sakasai T, Miwa Y, Takahashi S, Yagami KI, Sugiyama F
    • Journal Title

      Experimental Animals

      Volume: 66 Issue: 4 Pages: 437-445

    • DOI

      10.1538/expanim.17-0049

    • NAID

      130006187194

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Promoting stem sap flow of sweetpotatoes under low gravity with forced air movements2017

    • Author(s)
      Tokuda, A., Kitaya, Y., Hirai, H., Yano, S
    • Journal Title

      Trans. JSASS Aerospace Tech. Japan

      Volume: 16(1) Issue: 1 Pages: 53-56

    • DOI

      10.2322/tastj.16.53

    • NAID

      130006301931

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Research and development of radioprotective agents: A mini-review2017

    • Author(s)
      Fazliana Mohd Saaya, Takanori Katsube, Yi Xie, Kaoru Tanaka, Kazuko Fujita, Bing Wang
    • Journal Title

      International Journal of Radiology

      Volume: 4 (2-3) Pages: 128-138

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Entire photodamaged chloroplasts are transported to the central vacuole by autophagy2017

    • Author(s)
      Izumi M, Ishida H, Nakamura S and Hidema J
    • Journal Title

      Plant Cell

      Volume: 29(2) Issue: 2 Pages: 377-394

    • DOI

      10.1105/tpc.16.00637

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Moxd1 Is a Marker for Sexual Dimorphism in the Medial Preoptic Area, Bed Nucleus of the Stria Terminalis and Medial Amygdala2017

    • Author(s)
      Tsuneoka Y and Funato H et al.
    • Journal Title

      Front Neuroanat

      Volume: 11 Pages: 26-26

    • DOI

      10.3389/fnana.2017.00026

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Secretome analysis to elucidate metalloprotease-dependent ectodomain shedding of glycoproteins during neuronal differentiation2017

    • Author(s)
      Tsumagari K, Shirakabe K, Ogura M, Sato F, Ishihama Y and Sehara-Fujisawa A
    • Journal Title

      Gene to Cells

      Volume: 22(2) Issue: 2 Pages: 237-244

    • DOI

      10.1111/gtc.12466

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Impact of a simulated gravity load for atmospheric reentry, 10 g for 2 min, on conscious mice2017

    • Author(s)
      Morita H, Yamaguchi A, Shiba D, Shirakawa M and Takahashi S
    • Journal Title

      Journal of Physiological Sciences

      Volume: Epub ahead of print Issue: 4 Pages: 531-537

    • DOI

      10.1007/s12576-017-0526-z

    • NAID

      40021238561

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Design and Synthesis of Potent and Highly Selective Orexin 1 Receptor Antagonists with a Morphinan Skeleton and Their Pharmacologies2017

    • Author(s)
      Nagase H and Yanagisawa M et al.
    • Journal Title

      J Med Chem

      Volume: 60 Issue: 3 Pages: 1018-1040

    • DOI

      10.1021/acs.jmedchem.6b01418

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Development and performance evaluation of a three-dimensional clinostat synchronized heavy-ion irradiation system2017

    • Author(s)
      Ikeda H, Hidema J and Takahashi A et al.
    • Journal Title

      Life Sci Space Res

      Volume: 12 Pages: 51-60

    • DOI

      10.1016/j.lssr.2017.01.003

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Risk assessment of neonatal exposure to low frequency noise based on balance in mice2017

    • Author(s)
      Ohgami N et al.
    • Journal Title

      Front Behav Neurosci

      Volume: 11 Pages: 30-30

    • DOI

      10.3389/fnbeh.2017.00030

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Forward-genetics analysis of sleep in randomly mutagenized mice2016

    • Author(s)
      Funato H and Yanagisawa M et al.
    • Journal Title

      Nature

      Volume: 539(7629) Issue: 46 Pages: 378-383

    • DOI

      10.1038/nature20142

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein.2016

    • Author(s)
      Hashimoto T, Horikawa DD, Saito Y, Kuwahara H, Kozuka-Hata H, Shin-I T, Minakuchi Y, Ohishi K, Motoyama A, Aizu T, Enomoto A, Kondo K, Tanaka S, Hara Y, Koshikawa S, Sagara H, Miura T, Yokobori S, Miyagawa K, Suzuki Y, Kubo T, Oyama M, Kohara Y, Fujiyama A, Arakawa K, Katayama T, Toyoda A and Kunieda T
    • Journal Title

      Nature Communications

      Volume: 7 Issue: 1 Pages: 12808-12808

    • DOI

      10.1038/ncomms12808

    • NAID

      120005971035

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of mutations through dominant screening for obesity using C57BL/6 substrains2016

    • Author(s)
      Hossain MS., Funato H, and Yanagisawa M et al.
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 32453-32453

    • DOI

      10.1038/srep32453

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Long-term exposure to microgravity impairs vestibulo-cardiovascular reflex2016

    • Author(s)
      Morita H, Abe C and Tanaka K
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 33405-33405

    • DOI

      10.1038/srep33405

    • NAID

      120007017301

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Acute transcriptional up-regulation specific to osteoblasts/osteoclasts in medaka fish immediately after exposure to microgravity2016

    • Author(s)
      Chatani M et al.
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 39545-39545

    • DOI

      10.1038/srep39545

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Manganese-mediated acceleration of age-related hearing loss in mice2016

    • Author(s)
      Ohgami N et al.
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 36306-36306

    • DOI

      10.1038/srep36306

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] The vestibular system is critical for the changes in muscle and bone induced by hypergravity2016

    • Author(s)
      Kawao N, Morita H, Obata K, Tamura Y, Okumoto K and Kaji H
    • Journal Title

      Physiological Reports

      Volume: 4(19) Issue: 19 Pages: 12979-12979

    • DOI

      10.14814/phy2.12979

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator.2016

    • Author(s)
      Akiyama N, Takizawa N, Miyauchi M, Yanai H, Tateishi R, Shinzawa M, Yoshinaga R, Kurihara M, Demizu Y, Yasuda H, Yagi S, Wu G, Matsumoto M, Sakamoto R, Yoshida N, Penninger JM, Kobayashi Y, Inoue J, Akiyama T.
    • Journal Title

      The Journal of Experimental Medicine

      Volume: 213 Issue: 8 Pages: 1441-1458

    • DOI

      10.1084/jem.20151780

    • NAID

      120006532434

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis2016

    • Author(s)
      Harada H et al.
    • Journal Title

      Oncotarget

      Volume: 7(40) Issue: 40 Pages: 65837-65848

    • DOI

      10.18632/oncotarget.11670

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] ADAM12-deficient zebrafish exhibit retardation in body growth at the juvenile stage without developmental defects2016

    • Author(s)
      Tokumasu Y, Iida A, Wang Z, Ansai S, Kinoshita M, and Sehara-Fujisawa A
    • Journal Title

      Development, Growth & Differentiation

      Volume: 58(4) Pages: 409-421

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Novel roles of FKBP5 in muscle alteration induced by gravity change in mice2016

    • Author(s)
      Shimode T, Kawao N, Tamura Y, Morita H and Kaji H
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 479 Issue: 3 Pages: 602-606

    • DOI

      10.1016/j.bbrc.2016.09.126

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A New System for Three-dimensional Clinostat Synchronized X-irradiation with a High-speed Shutter for Space Radiation Research2016

    • Author(s)
      Ikeda H, Hidema J and Takahashi A et al.
    • Journal Title

      Biological Sciences in Space

      Volume: 30 Issue: 0 Pages: 8-16

    • DOI

      10.2187/bss.30.8

    • NAID

      130005306533

    • ISSN
      0914-9201, 1349-967X
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Characterization of fungi isolated from the equipment used in the International Space Station or Space Shuttle2016

    • Author(s)
      Satoh K, Yamazaki T and Makimura K et al.
    • Journal Title

      Microbiol Immunol

      Volume: 60(5) Issue: 5 Pages: 295-302

    • DOI

      10.1111/1348-0421.12375

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Fluorescence-Activated Cell Sorting and Gene Expression Profiling of GFP-Positive Cells from Transgenic Zebrafish Lines2016

    • Author(s)
      Tanabe H and Kawakami K et al.
    • Journal Title

      Methods in Molecular Biology

      Volume: 1451 Pages: 93-106

    • DOI

      10.1007/978-1-4939-3771-4_7

    • ISBN
      9781493937691, 9781493937714
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Microgravity elicits reproducible alterations in cytoskeletal and metabolic gene and protein expression in space-flown Caenorhabditis elegans2016

    • Author(s)
      Higashibata A., Hashizume T., Nemoto K., Higashitani N., Etheridge T., Mori C., Harada S., Sugimoto T., Szewczyk NJ., Baba SA., Mogami Y., Fukui K., Higashitani A.
    • Journal Title

      npj Microgravity

      Volume: 2 Issue: 1 Pages: 15022-15022

    • DOI

      10.1038/npjmgrav.2015.22

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Fluid dynamics alter Caenorhabditis elegans body length via TGF-beta/DBL-1 neuromuscular signaling2016

    • Author(s)
      Harada S., Hashizume T., Nemoto K., Shao Z., Higashitani N., Etheridge T., Szewczyk NJ., Fukui K., Higashibata A., Higashitani A.
    • Journal Title

      npj Microgravity

      Volume: 2 Issue: 1 Pages: 16006-16006

    • DOI

      10.1038/npjmgrav.2016.6

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] The relationship between widespread changes in gravity and cerebral blood flow2016

    • Author(s)
      Ogawa Y, Yanagida R, Ueda K, Aoki K, Iwasaki K
    • Journal Title

      Environmental Health and Preventive Medicine

      Volume: in press Issue: 4 Pages: 186-192

    • DOI

      10.1007/s12199-016-0513-7

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Intrathecal morphine-3-glucuronide-induced nociceptive behavior via δ-2 opioid receptors in the spinal cord2016

    • Author(s)
      Takaaki Komatsu, Soh Katsuyama, Hiroshi Nagase, Hirokazu Mizoguchi, Chikai Sakurada, Minoru Tsuzuki, Shinobu Sakurada, Tsukasa Sakurada
    • Journal Title

      Pharmacology Biochemistry & Behavior

      Volume: 140 Pages: 68-74

    • DOI

      10.1016/j.pbb.2015.10.010

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Opioid systems in the lateral hypothalamus regulate feeding behavior through orexin and GABA neurons.2016

    • Author(s)
      Ardianto C, Yonemochi N, Yamamoto S, Yang L, Takenoya F, Shioda S, Nagase H, Ikeda H, Kamei J.
    • Journal Title

      Neuroscience.

      Volume: 320 Pages: 183-193

    • DOI

      10.1016/j.neuroscience.2016.02.002

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] High-fat diet feeding alters olfactory-, social-, and reward-related behaviors of mice independent of obesity.2016

    • Author(s)
      Takase K, Tsuneoka Y, Oda S, Kuroda M, Funato H
    • Journal Title

      Obesity

      Volume: 4 Issue: 4 Pages: 886-894

    • DOI

      10.1002/oby.21441

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Sleep as a biological problem: an overview of frontiers in sleep research2016

    • Author(s)
      Kanda T, Tsujino N, Kuramoto E, Koyama Y, Susaki EA, Chikahisa S, Funato H
    • Journal Title

      J Physiol Sci

      Volume: 66 Issue: 1 Pages: 1-13

    • DOI

      10.1007/s12576-015-0414-3

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Nighttime administration of nicotine improves hepatic glucose metabolism via the hypothalamic orexin system in mice.2016

    • Author(s)
      Tsuneki H, Nagata T, Fujita M, Kon K, Wu N, Takatsuki M, Yamaguchi K, Wada T, Nishijo H, Yanagisawa M, Sakurai T, Sasaoka T.
    • Journal Title

      Endocrinology

      Volume: 157 Issue: 1 Pages: 195-206

    • DOI

      10.1210/en.2015-1488

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Plant nuclei move to escape ultraviolet-induced DNA damage and cell death.2016

    • Author(s)
      Iwabuchi K., Hidema J., Tamura K., Takagi S., Hara-Nishimura I.
    • Journal Title

      Plant Physiology

      Volume: 170 Issue: 2 Pages: 678-685

    • DOI

      10.1104/pp.15.01400

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comprehensive analysis of the skin fungal microbiota of astronauts during a half-year stay at the International Space Station2016

    • Author(s)
      Sugita T, Yamazaki T, Makimura K, Cho O, Yamada S, Ohshima H, Mukai C
    • Journal Title

      Med Mycol

      Volume: published online Issue: 3 Pages: 232-239

    • DOI

      10.1093/mmy/myv121

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Phylogenetic analysis of dermatophyte species using DNA sequence polymorphism in calmodulin gene2016

    • Author(s)
      Ahmadi B, Mirhendi H, Makimura K, de Hoog GS, Shidfar MR, Nouripour-Sisakht S, Jalalizand N
    • Journal Title

      Med Mycol

      Volume: published online Issue: 5 Pages: 500-514

    • DOI

      10.1093/mmy/myw004

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Fatal Cyberlindnera fabianii fungemia in a patient with mixed phenotype acute leukemia after umbilical cord blood transplantation2016

    • Author(s)
      Katagiri S, Gotoh M, Tone K, Akahane D, Ito Y, Ohyashiki K, Makimura K
    • Journal Title

      Int J Hematol

      Volume: published online Issue: 5 Pages: 592-595

    • DOI

      10.1007/s12185-016-1953-y

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Epidemiological aspects of Dermatophytosis in Khusestan, southwestern Iran, an update2016

    • Author(s)
      Razaei-Matehkolaei A, Rafiei A, Makimura K, Graser Y, Gharghani M, Sadeghi-Nejad B
    • Journal Title

      Mycopathologia

      Volume: published online Issue: 7-8 Pages: 547-553

    • DOI

      10.1007/s11046-016-9990-x

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Must but not Mir-335 affects skeletal muscle growth and regeneration2015

    • Author(s)
      Hiramuki Y, Sato T, Furuta Y, Surani A, Sehara-Fujisawa A
    • Journal Title

      PLoS ONE

      Volume: 10 Issue: 6 Pages: e0130436-e0130436

    • DOI

      10.1371/journal.pone.0130436

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] High-resolution live imaging reveals axon-glia interactions during peripheral nerve injury and repair in zebrafish2015

    • Author(s)
      Xiao Y, Faucherre A, Pola-Morell L, Heddleston J, Liu T, Chew T, Sato F, Sehara-Fujisawa A, Kawakami K, Lopez-Schier H
    • Journal Title

      Disease Models & Mechanisms

      Volume: 8 Issue: 6 Pages: 553-64

    • DOI

      10.1242/dmm.018184

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Early pathogenesis of Duchenne muscular dystrophy modelled in patient-derived human induced pluripotent stem cells2015

    • Author(s)
      Shoji E, Sakurai H, Nishino T, Nakahata T, Heike T, Awaya T, Fujii N, Manabe Y, Matsuo M, Sehara-Fujisawa A
    • Journal Title

      Sci Rep

      Volume: 5 Issue: 1 Pages: 12831-12831

    • DOI

      10.1038/srep12831

    • NAID

      120005649326

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Molecular dynamics study on protein-water interplay in the mechanogating of the bacterial mechanosensitive channel MscL2015

    • Author(s)
      Sawada Y, Sokabe M
    • Journal Title

      Eur J Biophys

      Volume: 44 Issue: 7 Pages: 531-43

    • DOI

      10.1007/s00249-015-1065-2

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Unidirectional incorporation of a bacterial mechanosensitive channel into liposomal membranes2015

    • Author(s)
      Nomura T, Cox CD, Bavi N, Sokabe M and Martinac B
    • Journal Title

      FASEB J.

      Volume: 29 Issue: 10 Pages: 4334-45

    • DOI

      10.1096/fj.15-275198

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Ion channels activated by mechanical forces in bacterial and eukaryotic cells2015

    • Author(s)
      Sokabe M, Sawada M, Kobayashi T
    • Journal Title

      Subcell Biochem

      Volume: 72 Pages: 613-626

    • DOI

      10.1007/978-94-017-9918-8_28

    • ISBN
      9789401799171, 9789401799188
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hypergravity provokes a temporary reduction in CD4+CD8+ thymocyte number and a persistent decrease in medullary thymic epithelial cell frequency in mice.2015

    • Author(s)
      Tateishi R, Akiyama N, Miyauchi M, Yoshinaga R, Sasanuma H, Kudo T, Shimbo M, Shinohara M, Obata K, Inoue J, Shirakawa M, Shiba D, Asahara H, Yoshida N, Takahashi S, Morita H, Akiyama T
    • Journal Title

      PLOS ONE

      Volume: 10 Issue: 10 Pages: 1-17

    • DOI

      10.1371/journal.pone.0141650

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Feasibility of a short-arm centrifuge for mouse hypergravity experiments2015

    • Author(s)
      Morita H, et al.
    • Journal Title

      PLOS ONE

      Volume: 10(7): e133981 Issue: 7 Pages: 1-14

    • DOI

      10.1371/journal.pone.0133981

    • NAID

      120007136296

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Role of osteoclasis in the heterotopic ossification enhanced by fobrodysplasia ossificans progressiva-related activin-like kinase 2 mutation in mice2015

    • Author(s)
      Kawao N, Yano M, Tamura Y, Okumoto K, Okada K, Kaji H
    • Journal Title

      J Bone Miner Metab

      Volume: epub

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical charasteristics of patients with abnornal ocular/cervical vestibular evoked myogenic potentials in the presence of normal caloric responses2015

    • Author(s)
      Iwasaki S, Fujimoto C, Kinoshita M, Kamogashira T, Egami N, Yamasoba T
    • Journal Title

      Ann Otol Rhinol Laryngol

      Volume: 124 Pages: 458-65

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effect of center-of-pressure power spectrum in foam posturography.2015

    • Author(s)
      Fujimoto C, Egami N, Demura S, Yamasoba T, Iwasaki S.
    • Journal Title

      Neurosci Lett.

      Volume: 585 Pages: 92-7

    • DOI

      10.1016/j.neulet.2014.11.033

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transformation of naltrexone into mesembrane and investigation of the binding properties of its intermediate derivatives to opioid receptors2015

    • Author(s)
      Konoura K, Fujii H, Imaide S, Gouda H, Hirayama S, Hirono S, Nagase H
    • Journal Title

      Bioorg Med Chem

      Volume: 23 Issue: 3 Pages: 439-48

    • DOI

      10.1016/j.bmc.2014.12.032

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Peripheral opioid antagonist enhances the effect of anti-tumor drug by blocking a cell growth-suppressive pathway in vivo2015

    • Author(s)
      Masami Suzuki, Fumiko Chiwaki, Yumi Sawada, Maho Ashikawa, Kazuhiko Aoyagi, Takeshi Fujita, Kazuyoshi Yanagihara, Masayuki Komatsu, Minoru Narita, Tsutomu Suzuki, Hiroshi Nagase, Ryoji Kushima, Hiromi Sakamoto, Takeo Fukagawa, Hitoshi Katai, Hitoshi Nakagama, Teruhiko Yoshida, Yasuhito Uezono, Hiroki Sasaki
    • Journal Title

      PLOS ONE

      Volume: 10(4) Issue: 4 Pages: 1-18

    • DOI

      10.1371/journal.pone.0123407

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Naltrindole derivatives with fluorinated ethyl substituents on 17-nitrogen as delta opioid receptor inverse agonist2015

    • Author(s)
      Nemoto T, Iihara Y, Hirayama S, Iwai T, Higashi E, Fujii H, Nagase H
    • Journal Title

      Bioorg Med Chem Lett

      Volume: 25 Issue: 15 Pages: 2927-30

    • DOI

      10.1016/j.bmcl.2015.05.038

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Investigation of 7-benzylidenenaltrexone derivatives as a novel structural antitrichomonal lead compound2015

    • Author(s)
      Kutsumura, N.; Nakajima, R.; Koyama, Y.; Miyata, Y.; Saitoh, T.; Yamamoto, N.; Iwata, S.; Fujii, H.; Nagase, H.
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 25 Issue: 21 Pages: 4890-4892

    • DOI

      10.1016/j.bmcl.2015.06.002

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Inhibition of opioid systems in the hypothalamus as well as the mesolimbic area suppresses feeding behavior of mice2015

    • Author(s)
      Ikeda H, Ardianto C, Yonemochi N, Yang L, Ohashi T, Ikegami M, Nagase H, Kamei J
    • Journal Title

      Neuroscience

      Volume: 311 Pages: 9-21

    • DOI

      10.1016/j.neuroscience.2015.10.002

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Design and Synthesis of Non-Peptide, Selective Orexin Receptor 2 Agonists2015

    • Author(s)
      Nagahara T, Saitoh T, Kutsumura N, Irukayama-Tomobe Y, Ogawa Y, Kuroda D, Gouda H, Kumagai H, Fujii H, Yanagisawa M, Nagase H
    • Journal Title

      J. Med. Chem

      Volume: 58 Issue: 20 Pages: 7931-7937

    • DOI

      10.1021/acs.jmedchem.5b00988

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of new opioid derivatives with a propellane skeleton and their pharmacologies: Part 5, novel pentacyclic propellane derivatives with a 6-amide side chain2015

    • Author(s)
      Nakajima R, Yamamoto N, Hirayama S, Iwai T, Saitoh A, Nagumo Y, Fujii H, Nagase H.
    • Journal Title

      Bioorg Med Chem.

      Volume: 23 Issue: 19 Pages: 6271-6279

    • DOI

      10.1016/j.bmc.2015.08.036

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Endothelin-1 as a master regulator of whole-body Na+ homeostasis2015

    • Author(s)
      Speed JS, Heimlich JB, Hyndman KA, Fox BM, Patel V, Yanagisawa M, Pollock JS, Titze JM, Pollock DM
    • Journal Title

      FASEB J

      Volume: 29 Issue: 12 Pages: 4937-44

    • DOI

      10.1096/fj.15-276584

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Functional ETA-ETB receptor cross-talk in basilar artery in situ from ETB receptor deficient rats2015

    • Author(s)
      Yoon S, Gariepy CE, Yanagisawa M, Zuccarello M, Rapoport RM
    • Journal Title

      J Cardiovasc Pharmacol

      Volume: epub

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 長期宇宙滞在時に解決すべき医学的課題~循環制御関連を中心に~2015

    • Author(s)
      古川聡
    • Journal Title

      循環制御

      Volume: 36 Pages: 66-8

    • Related Report
      2015 Annual Research Report
    • Open Access
  • [Journal Article] UV-B-Induced CPD photolyase gene expression is regulated by UVR8-dependent and -independent pathways in Arabidopsis.2015

    • Author(s)
      Li N, Teranishi M, Yamaguchi H, Matsushita T, Watahiki MK, Tsuge T, Li SS, Hidema J
    • Journal Title

      Plant and Cell Physiology

      Volume: 56 Issue: 10 Pages: 2014-2023

    • DOI

      10.1093/pcp/pcv121

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] From Arabidopsis to cereal crops: Conservation of chloroplast protein degradation by autophagy indicates its fundamental role in plant productivity.2015

    • Author(s)
      Izumi M, Hidema J, Ishida H
    • Journal Title

      Plant Signaling & Behavior

      Volume: 10 Issue: 11 Pages: e1101199-e1101199

    • DOI

      10.1080/15592324.2015.1101199

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Combining carbon ion irradiation and non-homologous end-joining repair inhibitor NU7026 efficiently kills cancer cells.2015

    • Author(s)
      Ma H, Takahashi A, Yoshida Y, Adachi A, Kanai T, Ohno T, Nakano T.
    • Journal Title

      Radiat Oncol

      Volume: 10 Issue: 1 Pages: 225-225

    • DOI

      10.1186/s13014-015-0536-z

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Targeting of Carbon Ion-Induced G2 Checkpoint Activation in Lung Cancer Cells Using Wee-1 Inhibitor MK-1775.2015

    • Author(s)
      Ma H, Takahashi A, Sejimo Y, Adachi A, Kubo N, Isono M, Yoshida Y, Kanai T, Ohno T, Nakano T.
    • Journal Title

      Radiat Res

      Volume: 184 Issue: 6 Pages: 660-669

    • DOI

      10.1667/rr14171.1

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A critical role of Dectin-1 in hypersensitivity pneumonitis2015

    • Author(s)
      Higashino-Kameda M, Yabe-Wada T, Matsuba S, Takeda K, Anzawa K, Mochizuki T, Makimura K, Saijo S, Iwakura Y, Toga H, Nakamura A
    • Journal Title

      Inflamm Res

      Volume: 65 Issue: 3 Pages: 235-44

    • DOI

      10.1007/s00011-015-0910-1

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Genetic and phenotypic analyses of Calcineurin A subunit in Arthroderma vanbreuseghemii2015

    • Author(s)
      Alshahni MM, Shimizu K, Yoshimoto M, Yamada T, Nishiyama Y, Arai T, Makimura K
    • Journal Title

      Med Mycol

      Volume: 54 Issue: 2 Pages: 207-18

    • DOI

      10.1093/mmy/myv088

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Dermatophytosis due to Microsporum incurvatum: notification and identification of a neglected pathogenic species2015

    • Author(s)
      Rezaei-Matehkolaei A, Makimura K, Graser Y, Seyedmousavi S, Abastabar M, Rafiei A, Zhan P, Ronagh A, Jafarpour S
    • Journal Title

      Mycopathologia

      Volume: 181 Issue: 1-2 Pages: 107-13

    • DOI

      10.1007/s11046-015-9946-6

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Microbes and crewed space habitat2015

    • Author(s)
      Yamaguchi N, Nasu M
    • Journal Title

      J Dis Res

      Volume: 10 Pages: 1022-4

    • NAID

      130007673462

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Microbial observatory research in the International Space Station and Japanese Experiment Module "Kibo"2015

    • Author(s)
      Shirakawa M, Tanigaki F, Yamazaki T
    • Journal Title

      J Dis Res

      Volume: 10 Pages: 1025-30

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Significance of changes in the skin fungal microbiomes of astronauts staying on the International Space Station2015

    • Author(s)
      Sugita T, Cho O
    • Journal Title

      J Dis Res

      Volume: 10 Pages: 1031-4

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Bacterial Monitoring in the International Space Station2015

    • Author(s)
      Ichijo T, Yamaguchi N, nasu M
    • Journal Title

      J Dis Res

      Volume: 10 Pages: 1035-9

    • Related Report
      2015 Annual Research Report
  • [Presentation] 廃用性筋萎縮と食成分2020

    • Author(s)
      *二川健
    • Organizer
      第22回健康栄養シンポジウム
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 宇宙医学から得られた筋萎縮に関する最新の知見2020

    • Author(s)
      *二川健
    • Organizer
      第29回泌尿器科分子・細胞研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 国際宇宙ステーション実験からえたUnloadingによる筋萎縮の分子メカニズム2020

    • Author(s)
      *二川健
    • Organizer
      第18回糖尿病運動療法研究会 2nd STAGE
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 寝たきりや無重力による筋萎縮の分子メカニズムとその栄養学的予防法の開発2020

    • Author(s)
      *二川健
    • Organizer
      第6回京都リハビリテーション医学会学術集会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] On how to prepare and use GUVs: From an experimental aspect2020

    • Author(s)
      Kanta Tsumoto
    • Organizer
      International Workshop on “Water Mediated Low-Dimensional Coulomb Systems” for Bilateral Joint Research Projects between JAPAN & SLOVENIA respectively supported by JSPS (Japan) and MESS (Slovenia)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 中枢時計におけるバソプレシン産生ニューロンの機能2020

    • Author(s)
      *三枝理博
    • Organizer
      第27回日本時間生物学会学術大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 両側前庭障害の診断と対策2020

    • Author(s)
      岩﨑真一
    • Organizer
      日本耳鼻咽喉科学会埼玉県地方部会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 障害者の骨をどう守る?2020

    • Author(s)
      篠原正浩
    • Organizer
      理論免疫ワークショップ
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Carbon-ion Cancer Radiotherapy: Double-Strand DNA Break Distribution and Repair2020

    • Author(s)
      Dylan J. Buglewicz, Hirokazu Hirakawa, Akira Fujimori, Takamitsu Kato
    • Organizer
      The 66th RRS Annual Meeting
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] High LET-like radiation tracks at the distal side of accelerated Proton Bragg peak2020

    • Author(s)
      Dakota Horendeck, Kade Walsh, Hirokazu Hirakawa, Akira Fujimori, Hisashi Kitamura, Takamitsu Kato
    • Organizer
      The 66th RRS Annual Meeting
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 病気を「知る」、「治す」ためのゲノム編集技術2020

    • Author(s)
      *宮本達雄
    • Organizer
      広島大学タマチラボ
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 真菌とヒトの健康障害;宇宙を含めた環境管理の可能性 ~真菌と共生するための空気清浄の役割~2020

    • Author(s)
      槇村浩一
    • Organizer
      第339回クリーンテクノロジー研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Does cancer progress faster in space? - My future plan of ISS-Kibo and Deep Space Gateway utilization experiments -2020

    • Author(s)
      Akihisa Takahashi
    • Organizer
      The 10th International Society of Radiation Neurobiology Conference ISRN-2020
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Combined effects of radiation and microgravity on the normal brain2020

    • Author(s)
      Yukari Yoshida, Espinosa-Jeffrey Araceli, Fernandez-Quezada David, Luquin de Anda Sonia, Akihisa Takahashi
    • Organizer
      The 10th International Society of Radiation Neurobiology Conference ISRN-2020
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 放射線生物学における低酸素バイオロジー2020

    • Author(s)
      原田浩
    • Organizer
      第49回京都放射線腫瘍研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 低酸素と放射線の関わり2020

    • Author(s)
      原田浩
    • Organizer
      第10回JASTRO放射線生物学セミナー
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Quantitative evaluation of the NBS1 I171V variant on radiosensitivity2020

    • Author(s)
      Tomioka K, Fujita K, Akutsu SN, Tauchi H, Yamamoto T, Kobayashi M, Kudo Y, Miyamoto T, *Matsuura S.
    • Organizer
      The 4th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] DNA 損傷応答に対する模擬宇宙環境の影響2020

    • Author(s)
      大泉昂之、山邉聡一郎、山之内佐久也、舟山和夫、高橋昭久、中村麻子
    • Organizer
      茨城大学理学部公開シンポジウム第13回Quantum Medicine研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Relationship between endogenous ROS accumulation and mitochondria responses under low dose rate irradiation2020

    • Author(s)
      Kobayashi J*, Meng Q., Komatsu K.
    • Organizer
      The 4th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 毛細血管拡張性運動失調症とATMキナーゼの役割2020

    • Author(s)
      小林純也*
    • Organizer
      第13回Quantum Medicine研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Recommendations for space radiation research2020

    • Author(s)
      Akihisa Takahashi
    • Organizer
      第13回Quantum Medicine
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] A novel hypoxia-inducible secretory protein, HISP2, causes radioresistance of hypoxic cancer cells in an autocrine manner2020

    • Author(s)
      Suwa T, Shirai Y, Kobayashi M, Mizowaki T, Harada H
    • Organizer
      Keystone Symposia; (Hypoxia: Molecules, Mechanisms and Disease)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A novel activator of HIF-1, ZBTB2, promotes invasion and growth of p53-deficient cancers2020

    • Author(s)
      Koyasu S, Harada H
    • Organizer
      Keystone Symposia; (Hypoxia: Molecules, Mechanisms and Disease)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] RNA sequencing of cell cycle-related genes in human fibroblasts exposed simultaneously to radiation and simulated microgravity2020

    • Author(s)
      Akihisa Takahashi, Hiroko Ikeda, Masafumi Muratani, Jun Hidema, Keigi Fujiwara, Hikaru Souda, Yukari Yoshida, Megumi Hada
    • Organizer
      2020 NASA Human Research Program Investigators’ Workshop
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Increased chromosome aberrations in lymphoblastoid cells exposed simultaneously to simulated microgravity and radiation2020

    • Author(s)
      Sakuya Yamanouchi, Jordan Rhone, Akihisa Takahashi, Megumi Hada
    • Organizer
      2020 NASA Human Research Program Investigators’ Workshop
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Increased protein phosphorylation and actin dynamics as early response in cells exposed to gravity changes.2020

    • Author(s)
      Keigi Fujiwara, Akihisa Takahashi, J. Wang, Z. Ju, Yukari Yoshida, Sakuya Yamanouchi, Megumi Hada
    • Organizer
      2020 NASA Human Research Program Investigators’ Workshop
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Plant culture system as a water recycling device in space farming2020

    • Author(s)
      Y. Kitaya
    • Organizer
      JpGU Meeting 2020, A-OS25 陸域海洋相互作用-惑星スケール物質循環 Continental-Oceanic Mutual Interaction: Planetary scale Material Circulation
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 細胞の個性を理解するための技術開発 Observing heterogeneity in cell society2020

    • Author(s)
      Asako Sakaue-Sawano, Atsushi Miyawaki
    • Organizer
      第10回国際放射線神経生物学会大会
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Unique adaptation strategies to extreme stresses in tardigrades2020

    • Author(s)
      Kunieda T.
    • Organizer
      Royal Society Theo Murphy international scientific meeting "Anhydrobiosis - cheating death and telling the tale"
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Implication of SAHS proteins in alleviation of oxidative stress in extracellular space.2020

    • Author(s)
      Tanaka A and Kunieda T.
    • Organizer
      Royal Society Theo Murphy international scientific meeting "Anhydrobiosis - cheating death and telling the tale"
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Molecular and biophysical mechanisms of substrate rigidity sensing that determines cell fate2019

    • Author(s)
      M Sokabe*, T Kobayashi
    • Organizer
      第42回日本分子生物学会年会 シンポジウム2PS-01 Functions and Mechanisms of Force in Animal and Plant Live
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Functional space foods improve the QOL in moon village2019

    • Author(s)
      *Takeshi Nikawa
    • Organizer
      The 3rd International Moon Village Workshop & Symposium
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Establishing an international institute for the development of next-generation space nutrition researchers2019

    • Author(s)
      *Takeshi Nikawa
    • Organizer
      The 3rd International Moon Village Workshop & Symposium
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 第一回きぼうマウスミッション概要と成果2019

    • Author(s)
      高橋 智
    • Organizer
      薬物動態学会
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 国際宇宙ステーション(ISS)「きぼう」実験棟でのマウス宇宙実験の概要2019

    • Author(s)
      高橋 智
    • Organizer
      東北実験動物研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] ツメガエル胚の領域規定における細胞張力・細胞形状の関与2019

    • Author(s)
      道上達男
    • Organizer
      第5回幹細胞研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Aqueous/Aqueous Microdroplets: Their Stability and Reactivity with Biomacromolecules2019

    • Author(s)
      Kanta Tsumoto*, Yusuke Fujise, Hiroki Sakuta, Kingo Takiguchi, Kenichi Yoshikawa, Masahiro Tomita
    • Organizer
      OKINAWA COLLOIDS 2019 [S5] Science & Technologies for the Sustainable Space Colony Life
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cooperation between DNA and Actin in Cell-Sized Aqueous/Aqueous Micro Droplet2019

    • Author(s)
      Hiorki Sakuta, Masahito Hayashi, Kingo Takiguchi, Kanta Tsumoto, Kenichi Yoshikaw*
    • Organizer
      OKINAWA COLLOIDS 2019 [S3] Membranous and Membraneless Interfaces: Towards Artificial Cellular Complexity
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] he neural circuit for prey capture in zebrafish: from visual stimuli to the hypothalamic feeding center2019

    • Author(s)
      Koichi Kawakami, Akira Muto
    • Organizer
      Cold Spring Harbor Laboratory Meeting
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Analysis of tooth replacement mechanism using genetically modified medaka fish2019

    • Author(s)
      *Chatani M, Azetsu Y, Dodo Y, Sakai N, Kudo A, Takami M
    • Organizer
      第61回歯科基礎医学会学術大会
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 細胞も相分離してるんです~複雑な内部構造の起源に迫る~2019

    • Author(s)
      湊元幹太*
    • Organizer
      日本化学会秋季事業 第9回 CSJ化学フェスタ2019
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 初期胚の神経領域規定における物理的な力の関与2019

    • Author(s)
      道上達男
    • Organizer
      第14回日本臨床ストレス応答学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 神経から筋・代謝へのメカノストレス伝達と適応応答2019

    • Author(s)
      東谷篤志、Surabhi Sudevan、 東谷 なほ子、橋爪 藤子、東端 晃
    • Organizer
      第33回大会 日本宇宙生物科学会 特別シンポジウム
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] メダカの宇宙適応を基盤とした骨研究2019

    • Author(s)
      茶谷 昌宏
    • Organizer
      日本宇宙生物科学会 第33回大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 機能性宇宙食の開発2019

    • Author(s)
      二川健
    • Organizer
      第66回日本栄養改善学会学術総会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] パネルディスカッション(1)「きぼう・こうのとり 成果と今後の展望(仮)」2019

    • Author(s)
      高橋 智
    • Organizer
      きぼう・こうのとり10周年記念公開シンポジウム開催
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 廃用性筋萎縮の分子メカニズムとその栄養学的予防法2019

    • Author(s)
      二川健
    • Organizer
      第5回Neo VitamineD Workshop学術集会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 無重力や寝たきりによる筋萎縮に有効な機能性宇宙食の開発2019

    • Author(s)
      二川健
    • Organizer
      日本食品科学工業会 第66回大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Self-Emerging Cooperative Localization of DNA and Actin in Cell-Sized Aqueous/Aqueous Droplet2019

    • Author(s)
      H Sakuta, M Hayashi, K Takiguchi, K Tsumoto, K Yoshikawa
    • Organizer
      12thEBSA and 10th ICBP-IUPAP Biophysics Congress
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Practicalities of sending C. elegans to space and the similarities of the worm’s adaptations to spaceflight and ageing.2019

    • Author(s)
      Atsushi Higashitani.
    • Organizer
      22nd International C. elegans Conference
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Ca2+ overload due to mitochondrial dysfunction causes muscle ECM degradation.2019

    • Author(s)
      Surabhi Sudevan, Mai Takiura, Yukihiko Kubota, Nahoko Higashitani, Michael Cooke, Rebecca A Ellwood, Timothy Etheridge, Nathaniel J Szewczyk, Atsushi Higashitani
    • Organizer
      the 22nd International C. elegans Conference
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Bridging the Physiologic Gap: Using C. elegans to Improve Human Skeletal Muscle Health2019

    • Author(s)
      Atsushi Higashitani
    • Organizer
      the 22nd International C. elegans Conference
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Metabolic flow from glycolysis to TCA cycle is critical for skeletal muscle stem cell differentiation and myotube formation during regeneration in mice2019

    • Author(s)
      Shimpei Hori, Yosuke Hiramuki, Daigo Nishimura, Fuminori Sato, Atsuko Sehara-Fujisawa
    • Organizer
      2019 Myogenesis Gordon Research Conference
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Reactive oxygen species upregulate expression of muscle atrophy-associated ubiquitin ligase Cbl-b in rat L6 skeletal muscle cells.2019

    • Author(s)
      Takayuki Uchida, Yoshihiro Sakashita, Katsuya Hirasaka, Ayako Ohno, Reiko Nakao, Akira Higashibata, Takeshi Kobayashi, Masahiro Sokabe, Takeshi Nikawa
    • Organizer
      ADVANCED BIOMEDICAL ENGINEERING AND INSTRUMENTATION SUMMIT
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Roles of a transcription factor 19A intheosteoblastdevelopmentof sternum2019

    • Author(s)
      Mao KURIKI, Fuminori SATO, Kenta SUMIYAMA, Kouichi KAWAKAMI, Atsuko SEHARA-FUJISAWA
    • Organizer
      ECTS(European Calcified Tissue Society)2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Impact of space flight or simulated microgravity combined with space radiation exposure on retinal oxidative damage2019

    • Author(s)
      X. W. Mao, Marjan Boerma, George Nelson, Dai Shiba, Masaki Shirakawa, Satoru Takahashi, Michael Delp
    • Organizer
      The International Society for Gravitational Physiology(ISGP)2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 無重力によるミトコンドリア機能異常と筋萎縮2019

    • Author(s)
      二川健
    • Organizer
      第92回日本整形外科学会学術総会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Artificial membranes presenting membrane proteins delivered by revombinant baculovirus particles2019

    • Author(s)
      Kanta Tsumoto, Kohei Nakanishi, Seiwa Nishio and Masahiro Tomita
    • Organizer
      The 7th Chaina-Japan Symposium on Nanomedicine
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Transposon-mediated genetic methods in zebrafish and their applications to the study of functional neural circuits2019

    • Author(s)
      Koichi Kawakami
    • Organizer
      The first internationall zebrafish workshop in Qatar
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 難治性掻痒症治療薬ナルフラフィンの研究・開発とオレキシン受容体拮抗薬の設計・合成2019

    • Author(s)
      長瀬博
    • Organizer
      富山大学大学院生命融合科学教育部 特別講演会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Effects of the gene expression of hypothalamic feeding-regulating neuropeptides after being exposed to different gravity in mice via vestibular inputs2019

    • Author(s)
      Satomi Sonoda, Mitsuhiro Yoshimura, Kazuhiko Baba, Kenya Sanada, Kazuaki Nishimura, Haruki Nishimura, Kentaro Tanaka, Takashi Maruyama, Chikara Abe, Hironobu Morita, *Yoichi Ueta
    • Organizer
      Neuroscience of Energy Balance 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] モデルマウスを用いた骨融解症の病態理解 ー遺伝子欠損から疾患変異へー2019

    • Author(s)
      綱川 祐貴, 篠原 正浩
    • Organizer
      第42回日本分子生物学会年会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 環境因子が影響する難聴の予知・予防法の解析2019

    • Author(s)
      大神信孝
    • Organizer
      第29回日本医療薬学会年会 公募シンポジウム 「難病治療における薬剤師の関わり ~根治療法のない疾患に薬剤師はどう向き合うのか?~
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 教育講演:宇宙で快適に生きるために:前庭系の可塑的変化2019

    • Author(s)
      *森田啓之
    • Organizer
      第72回日本自律神経学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Design and synthesis of orexin receptor selective ligands and their pharmacology2019

    • Author(s)
      Hiroshi Nagase
    • Organizer
      Novel Pain Therapeutics: From Basic Research to Clinical Translation and Rehabilitation
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Design and synthesis of orexin receptor selective ligands and their pharmacology2019

    • Author(s)
      Hiroshi Nagase
    • Organizer
      Roman Pharmacists Association
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Time-series change in interpersonal relationships and mental health: 15-days confinement study in Japan.2019

    • Author(s)
      Yuichi Oi, Go Suzuki, Shotaro Doki, Shin-ichiro Sasahara, Ichiyo et al.
    • Organizer
      International Astronautical Congress 2019 (IAC2019)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Genetic dissection of the neural network of central circadian clock2019

    • Author(s)
      Michihiro Mieda
    • Organizer
      日本時間生物学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Gravity change and muscle/bone relationship.2019

    • Author(s)
      *Hiroshi Kaji.
    • Organizer
      Japan-Korea Joint Symposium:第37回日本骨代謝学会第21回日本骨粗鬆症学会合同学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Welcomeセミナー:重力生理学:動物実験から被験者実験へ2019

    • Author(s)
      *森田啓之
    • Organizer
      第53回日本実験動物技術者協会総会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 再生筋線維の肥大応答性を制御するエピジェネティック機構2019

    • Author(s)
      河野 史倫
    • Organizer
      第74回日本体力医学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Essential structure of orexin 1 receptor antagonist YNT-7072019

    • Author(s)
      Sayaka Ohrui, Naoshi Yamamoto, Takahiro Okada, Masahiro Yata, Tsuyoshi Saitoh, Noriki Kutsumura, Yasuyuki Nagumo, Yoko Irukayama-Tomobe, Yukiko Ishikawa, Yasuhiro Ogawa, Yurie Watanabe, Daichi Hayakawa, Hiroaki Gouda, Masashi Yanagisawa, *Hiroshi Nagase
    • Organizer
      27th International Society of Heterocyclic Chemistry Congress
    • Related Report
      2019 Annual Research Report
  • [Presentation] Different effects of orexin receptor antagonist and GABAA?agonist on physical and cognitive functions after forced awakening.2019

    • Author(s)
      J. Seol, Y. Fujii, I. Park, Y. Suzuki, F. Kawana, K. Yajima, S. Fukusumi, T. Okura, M. Satoh, K. Tokuyama, T. Kokubo, *M. Yanagisawa.
    • Organizer
      World Sleep 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] オレキシン阻害薬とGABAA作動薬の服用が強制覚醒時における身体機能および認知機能に及ぼす影響2019

    • Author(s)
      薛載勲, 藤井悠也, 朴寅成, 鈴木陽子, 川名ふさ江, 矢島克彦, 福住昌司, 大藏倫博, 佐藤誠, 徳山薫平, 小久保利雄, *柳沢正史
    • Organizer
      第33回日本宇宙生物科学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Dynamic cerebral autoregulation during flexion and extension of the neck in healthy adults2019

    • Author(s)
      Tomokazu Kato, Toru Konishi, Takuya Kurazumi, Chiharu Takko, Yojiro Ogawa, Ken-ichi Iwasaki
    • Organizer
      The ninth international meeting on Cerebral Haemodynamic Regulation (CARNet meeting) in collaboration with International Symposium on Intracranial Pressure and Neuromonitoring 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 前庭系を介する自律神経調節2019

    • Author(s)
      安部 力
    • Organizer
      新学術領域 温度を基軸とした生命現象の統合的理解(温度生物学) 若手の会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Possibility of anti-inflammatory effect via the vestibular system2019

    • Author(s)
      安部 力
    • Organizer
      第92回日本生化学会大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 筋・骨連関とマイオカイン.2019

    • Author(s)
      梶博史.
    • Organizer
      第5回日本筋学会学術集会. シンポジウム4 筋と他臓器との連関.
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Noisy galvanic vestibular stimulation as a treatment for bilateral vestibulopathy.2019

    • Author(s)
      Iwasaki S
    • Organizer
      3rd Seoul National University Bundang Hospital Dizziness Center Symposium
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 世界初のOX2R作動薬YNT-185の創出とその薬理作用2019

    • Author(s)
      長瀬博
    • Organizer
      第13回日本緩和医療薬学会年会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 独創的新薬の開発を目指して2019

    • Author(s)
      長瀬博
    • Organizer
      東京理科大学大学院基礎工学研究科 招待講演
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] モルヒナン骨格を基盤とする研究開発(独創的新薬の開発を目指して)2019

    • Author(s)
      長瀬博
    • Organizer
      日本薬学会中国四国支部 特別講演会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] オレキシン受容体選択的リガンドの設計・合成とその薬理作用2019

    • Author(s)
      長瀬博
    • Organizer
      2019年度東北医科薬科大学創薬研究センターシンポジウム
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Structured Review: Psychosocial Stress during Long-term Stays in Space2019

    • Author(s)
      Shin-ichiro SASAHARA, Yuichi OI, Shotaro DOKI, Daisuke HORI, Yuh OHTAKI, Christina-Sylvia ANDREA, Tsukasa TAKAHASHI, Nagisa SHIRAKI, Yu IKEDA, Tomohiko IKEDA, Ryutaro IZUMI, Tamaki SAITO, Ichiyo MATSUZAKI
    • Organizer
      ISTS
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] C1 neurons mediate a stress-induced protection of acute kidney injury2019

    • Author(s)
      Chikara Abe
    • Organizer
      International Symposium on Bio-CHAINs from Single Molecules to Highly Organized Systems
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Discovery of Novel Orexin Receptor Antagonist with 1,3,5-Trioxazatriquinane Skeleton2019

    • Author(s)
      Mao Amezawa, Jumpei Horiuchi, Tsuyoshi Saitoh, Yasuhiro Ogawa, Yukiko Ishikawa, Yoko Irukayama, Emi Hasegawa, Daichi Hayakawa, Yurie Watanabe, Yasuyuki Nagumo, Naoshi Yamamoto, Noriki Kutsumura, Hiroaki Gouda, Takeshi Sakurai, Masashi Yanagisawa, Hiroshi Nagase
    • Organizer
      The 27th French-Japanese Symposium on Medicinal and Fine Chemistry
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Time Course of Changes in Cerebral Oxygen Saturation by NIRS and Cerebral Blood Flow Velocity by TCD under Mild +Gz Hypergravity2019

    • Author(s)
      Toru Konishi, Takuya Kurazumi, Tomokazu Kato, Chiharu Takko, Yojiro Ogawa, Ken-ichi Iwasaki
    • Organizer
      90th Aerospace Medical Association (AsMA) Annual Scientific Meeting
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of certrifugation-induced hypergravity on the hypothalamic feeding-related neuropeptides gene expressions in mice via vestibular inputs.2019

    • Author(s)
      Yoichi Ueta, Satomi Sonoda, Mitsuhiro Yoshimura, Takashi Maruyama, Chikara Abe, Hironobu Morita
    • Organizer
      第40回国際重力生理学会・宇宙生命科学技術集会
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Thermoregulation through the glutamatergic neurons in vestibular nucleus complex2019

    • Author(s)
      Chikara Abe
    • Organizer
      EB 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] モルヒナン骨格を基盤とする研究開発-独創的新薬の創出を目指して-2019

    • Author(s)
      長瀬博
    • Organizer
      有機合成化学協会関東支部ミニシンポジウム
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Radiation-protective abilities of DADS, a garlic oil component in X-ray irradiated mice.2019

    • Author(s)
      Tetsuo Nakajima, Yasuharu Ninomiya and Mitsuru Nenoi
    • Organizer
      The 7th International Conference on Food Factors (ICoFF2019)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A link between activation of HIF-1 and defect in p532019

    • Author(s)
      Harada H
    • Organizer
      Precision Medicine Symposium, National Taiwan University
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Future Tasks for Plant Space Radiation Research Area2019

    • Author(s)
      Jun Hidema*
    • Organizer
      Joint Workshop by GIMRT & "Kibo" Users' Network of JAXA & AIRC
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] How to research about simulated space environments on the Earth2019

    • Author(s)
      Akihisa Takahashi
    • Organizer
      International Conference on Mechanical, Electrical and Medical Intelligent System 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Assessment of Cancer Risk from Radiation Hazard in Space2019

    • Author(s)
      Akihisa Takahashi
    • Organizer
      The 3rd International Moon Village Workshop and Symposium
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 「マンモスを再生せよ」に見るゲノム編集2019

    • Author(s)
      *宮本達雄
    • Organizer
      科学道100冊・サイエンスカフェ(東広島市産業振興課)
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 新規HIF-1活性化因子の発現スクリーニングで明らかになったHIF-1活性制御機構2019

    • Author(s)
      原田浩
    • Organizer
      第42回日本分子生物学会年会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Biological effects of high LET heavy ions in human blood lymphocytes and mouse cells2019

    • Author(s)
      P. Hande, D. Zeegers, S. Venkatesan, M. Seah, P. Velmurugan, S. Koh, S. Sethu, M. Jayapal, B. Banerjee, H. Hirakawa, C. Liu, R. Okayasu, A. Fujimori
    • Organizer
      第62回日本放射線影響学会大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Genomic and histopathological features of lung tumors in mice irradiated with different types of radiation2019

    • Author(s)
      鈴木 健之, 山崎 隼輔, 岩田 健一, 山田裕,  森岡 孝満, 臺野 和広, 甘崎 佳子, 上西 陸美, 小川 真里, 島田 義也, 柿沼 志津子
    • Organizer
      65th Annual Radiation Research Society Meeting
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] マウスのたまご、宇宙から帰る2019

    • Author(s)
      柿沼志津子
    • Organizer
      日本放射線影響学会第62回大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Radioresistance of cells; Lessons from hypoxia biology2019

    • Author(s)
      Harada H. Title TBA. The 3rd isRTB. Suzhou, China. Nov. 28, 2019
    • Organizer
      The 3rd isRTB
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 低酸素・腫瘍生物学研究で迫る癌治療増感2019

    • Author(s)
      原田浩
    • Organizer
      日本放射線腫瘍学会第32回学術大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Future Space Experiments for “Cancer Risk Assessment“2019

    • Author(s)
      Akihisa Takahashi
    • Organizer
      International Training Course on Carbon-ion Radiotherapy 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] まだまだ終わらない宇宙実験2019

    • Author(s)
      髙橋昭久
    • Organizer
      日本放射線影響学会第62回大会市民公開講座
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Expression Profile of Cell Cycle-related Genes in Human Fibroblasts Exposed Simultaneously to Radiation and Simulated Microgravity2019

    • Author(s)
      Akihisa Takahashi, Hiroko Ikeda, Masafumi Muratani, Jun Hidema, Megumi Hada, Keigi Fujiwara, Hikaru Souda, Yukari Yoshida
    • Organizer
      35th Annual Meeting of the American Society for Gravitational and Space Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Increased Chromosome Aberrations in Cells Exposed Simultaneously to Simulated Microgravity and Radiation2019

    • Author(s)
      Megumi Hada, Jordan Rhone, Andrew J Beitman, Hiroko Ikeda, Ianik Plante, Hikaru Souda, Yukari Yoshida, Kathryn D Held, Keigi Fujiwara, Premkumar B Saganti, Akihisa Takahashi
    • Organizer
      35th Annual Meeting of the American Society for Gravitational and Space Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 宇宙でガンの進行は早まるか?2019

    • Author(s)
      髙橋昭久
    • Organizer
      奈良県立医科大学招待講演
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 宇宙生存環境拡大のために:宇宙放射線と重力環境変化の複合影響研究2019

    • Author(s)
      髙橋昭久
    • Organizer
      京大定例オープンセミナー
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 放射線治療効果の予測に繋げる低酸素生物学研究2019

    • Author(s)
      原田浩
    • Organizer
      第57回日本癌治療学会学術集会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 宇宙環境における植物放射線影響研究の今後の課題2019

    • Author(s)
      日出間純*,髙橋昭久
    • Organizer
      マイクログラビティ応用学会第31回大会(JASMA31)
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 皮膚マイクロバイオーム:いかにしてマイクロバイオームと良い関係を構築するか2019

    • Author(s)
      杉田 隆
    • Organizer
      第70回日本皮膚科学会中部支部総会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] ISS搭載凍結受精卵に対する宇宙放射線の影響2019

    • Author(s)
      柿沼 志津子, 鶴岡 千鶴, 塚本 智史, 鬼頭 靖司, 小久保 年章, 和田 彩子, 畠山 朋美, 島田 義也, 矢野 幸子, 鈴木 智美, 東端 晃, 多田 基紀, 鈴木 ひろみ, 嶋津 徹
    • Organizer
      日本宇宙生物科学会 第33回大会,
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 宇宙微小重力・高紫外線複合環境ストレスに対する植物の応答:宇宙実験に何を期待するのか?"2019

    • Author(s)
      日出間純
    • Organizer
      日本宇宙生物科学会第36回大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 放射線と疑似微小重力複合影響:ヒト線維芽細胞における遺伝子発現解析2019

    • Author(s)
      佐藤文規, 呉泉, チェミンヨン, 髙橋昭久, 小林純也, 村谷匡史, 王梓, 藤田生水, 内田智子, 加藤充康, 谷垣文章, 東端晃, 今村聖実, 堀内映美, 川上浩一, 菅野純夫, 鈴木穣, 松崎文雄, 瀬原淳子
    • Organizer
      日本宇宙生物科学会第37回大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 「宇宙に生きる」ための宇宙放射線影響研究シナリオ2019

    • Author(s)
      髙橋 昭久
    • Organizer
      日本宇宙生物科学会第33回大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Is gravity parameter necessary for cancer risk assessment in long-term manned space missions?2019

    • Author(s)
      Akihisa Takahashi
    • Organizer
      7th International Systems Radiation Biology Workshop
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Cancer cell dormancy behind therapy resistance and recurrence of hypoxic cancer cells2019

    • Author(s)
      原田浩
    • Organizer
      第92回日本生化学会大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] A link between HIF-1 and defects in p53 under hypoxic stress2019

    • Author(s)
      Hiroshi HARADA
    • Organizer
      第78回日本癌学会学術総会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] BIOINDICATORS OF HEAVY ION EXPOSURES IN HUMAN LYMPHOCYTES: USE OF MOLECULAR CYTOGENETIC TECHNIQUES2019

    • Author(s)
      Dimphy ZEEGERS, Shriram VENKATESAN, Birendranath BANERJEE, Swaminathan SETHU, Manikandan JAYAPAL, Akira FUJIMORI, Ryuichi OKAYASU, Prakash HANDE*
    • Organizer
      第33回宇宙生物科学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Radiation exposure induces early onset of mouse precursor B-cell lymphoma with specific genomic aberrations2019

    • Author(s)
      Hirotaka Tachibana, Kazuhiro Daino, Takamitsu Morioka, Yi Shang, Atsuko Ishikawa, Mari Ogawa, Misuzu Fujita, Akira Matsuura, Hiroyuki Nogawa, Yoshiya Shimada, Shizuko Kakinuma
    • Organizer
      16th International Congress of Radiation Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Inhibitory effect of environmental enrichment on radiation-induced intestinal tumor in ApcMin/+ mice2019

    • Author(s)
      横溝 真哉, 西村 まゆみ, 森岡 孝満, 西村 由希子, 柳原 啓見, 鶴岡 千鶴, Kazumasa Inoue, Masahiro Fukushi, 柿沼 志津子, 島田 義也
    • Organizer
      16th International Congress of Radiation Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Age-dependent effects of 2 MeV fast neutrons on induction of medulloblastoma in Ptch1 heterozygous mice2019

    • Author(s)
      Chizuru Tsuruoka, Mutsumi Kaminishi, Mayumi Shinagawa, Yi Shang, Yoshiko Amasaki, Yoshiya Shimada, Shizuko Kakinuma
    • Organizer
      16th International Congress of Radiation Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Whole-exome sequencing analysis to identify somatic mutations in radiation-induced rat mammary carcinomas2019

    • Author(s)
      Hitomi Moriyama, Kazuhiro Daino, Tatsuhiko Imaoka, Masaru Takabatake, Takamitsu Morioka, Atsuko Ishikawa, Kazumasa Inoue, Masahiro Fukushi, Yoshiya Shimada, Shizuko Kakinuma
    • Organizer
      16th International Congress of Radiation Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 宇宙での長期滞在:宇宙放射線とガン死リスク"2019

    • Author(s)
      髙橋昭久
    • Organizer
      第一回探査の将来を考える勉強会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Characterization of Radioadaptive Response in a Mouse Model (Yonezawa Effect). ICRR.2019

    • Author(s)
      Bing Wang, Cuihua Liu, Kaoru Tanaka, Takanori Katsube, Hirokazu Hirakawa, Yasuharu Ninomiya, Kouichi Maruyama, Masahiro Murakami, Kazuko Fujita, Qiang Liu, Akira Fujimori, Mitsuru Nenoi.
    • Organizer
      ICRR(International Congress of Radiation Research)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of chronic restraint-induced stress and Fe-particle irradiation on induction of chromosomal aberrations in Trp53-heterozygous mice.2019

    • Author(s)
      Takanori Katsube, Bing Wang, Kaoru Tanaka, Yasuharu Ninomiya, Cuihua Liu, Hirokazu Hirakawa, Kouichi Maruyama, Guillaume Vares, Qiang Liu, Tetsuo Nakajima, Akira Fujimori, Mitsuru Nenoi
    • Organizer
      ICRR(International Congress of Radiation Research)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Psychosocial stress promotes radiation-induced acute damage in mice2019

    • Author(s)
      Tetsuo Nakajima, Yasuharu Ninomiya, Keiko Unno, Takamitsu Morioka, Mayumi Nishimura, Mitsuru Nenoi and Shizuko Kakinuma
    • Organizer
      ICRR(International Congress of Radiation Research)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Radioresistance of hypoxic tumor cells2019

    • Author(s)
      Hiroshi HARADA
    • Organizer
      The 16th International Congress for Radiation Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Novel hypoxia-inducible secretory protein, HISP2, cause radioresistance of cells in an autocrine manner2019

    • Author(s)
      Tatsuya SUWA, Minoru KOBAYASHI, Hiroshi HARADA
    • Organizer
      The 16th International Congress for Radiation Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ゲノム編集技術を用いたオーファン繊毛病の病因・病態解明2019

    • Author(s)
      宮本達雄
    • Organizer
      愛知医科大学 病理学セミナー
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Evaluation of radioprotective effect of piceatannol2019

    • Author(s)
      Kenta Takahashi, Ryoya Tetsuka, Ryoichi Hirayama, Takashi Shimokawa, Tsutomu Shimura, Asako J. Nakamura
    • Organizer
      16th International Congress of Radiation Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The effect of simulated space environment on DNA damage response2019

    • Author(s)
      Takashi Oizumi, Souichiro Yamabe, Tomoo Funayama, Akihisa Takahashi, Asako J. Nakamura
    • Organizer
      16th International Congress of Radiation Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Ptch1ヘテロ欠損マウスの髄芽腫発生モデルの放射線シグネチャーを用いた 低線量率リスク解析2019

    • Author(s)
      鶴岡 千鶴, 森岡 孝満, 上西 睦美, 品川 まゆみ, 島田 義也, 柿沼 志津子, Blyth Benjamin
    • Organizer
      アイソトープ・放射線研究発表会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] FISH analysis of chromosomal aberrations induced in?Trp53-heterozygous mice exposed to both?chronic?restraint-induced stress and Fe-particle irradiation. Workshop of Radiation Medicine and Protection2019

    • Author(s)
      Takanori Katsube, Bing Wang,?Kaoru Tanaka, Yasuharu Ninomiya, Hirokazu Hirakawa, Cuihua Liu, Kouichi?Maruyama, Guillaume Vares,?Qiang Liu, Tetsuo Nakajima, Akira Fujimori, Mitsuru Nenoi
    • Organizer
      Workshop of Radiation Medicine and Protection
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] New Progress in Characterization of Radioadaptive Response in a Mouse Model (Yonezawa Effect)2019

    • Author(s)
      Bing Wang, Cuihua Liu, Kaoru Tanaka, Takanori Katsube, Hirokazu Hirakawa, Yasuharu Ninomiya, Kouichi Maruyama, Masahiro Murakami, Kazuko Fujita, Qiang Liu, Akira Fujimori, Mitsuru Nenoi.
    • Organizer
      Workshop of Radiation Medicine and Protection
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] がん抑制機構と低酸素応答機構をつなぐ新規遺伝子の同定と活用2019

    • Author(s)
      原田浩
    • Organizer
      京都大学大学院生命科学研究科シンポジウム
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Temporary Loading Prevents Cancer Progression and Immune Organ Atrophy Induced by Hind-limb Unloading2019

    • Author(s)
      Akihisa Takahashi, Shoto Wakihata, Liqiu Ma, Takuya Adachi, Yukari Yoshida, Yoshinobu Ohira
    • Organizer
      32nd The International Symposium on Space Technology and Science (ISTS2019)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 16S rDNA- and rRNA-based community structures of bacteria in the Japanese module ‘Kibo’ of the International Space Station2019

    • Author(s)
      Kimiko Uchii, Kenji Shiomi, Naohiro Enokida, Tomoaki Ichijo, Katsuji Tani, Masao Nasu
    • Organizer
      32nd ISTS
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Human microbes dominate in a pharmaceutical manufacturing facility as a model of space habitat2019

    • Author(s)
      Tomoaki Ichijo, Mako Kawai, Takashi Sugita, Masao Nasu
    • Organizer
      32nd ISTS
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] CRISPR-ObLiGaRe法を用いたiPS細胞における蛍光核標識によるモザイク・トリソミー21のモデル細胞系の開発2019

    • Author(s)
      Silvia Natsuko Akutsu、落合博、山本卓、大橋博文、宮本達雄、松浦伸也
    • Organizer
      日本ゲノム編集学会第4回大会
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Gunma University Heavy Ion Medical Center (GHMC): Therapy and Space Research?2019

    • Author(s)
      Akihisa Takahashi
    • Organizer
      International Conference on Technology and Social Science 2019 (ICTSS 2019)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Space Experiments for "Cancer Progression" in the International Space Station2019

    • Author(s)
      Akihisa Takahashi, Masafumi Muratani, Asako Sawano, Atushi Miyawaki
    • Organizer
      40th Annual International Society for Gravitational Physiology Meeting (ISGP2019)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] DIALLYL DISULFIDE AMELIORATES RADIATION DAMAGE IN CELLS AND MICE2019

    • Author(s)
      Tetsuo Nakajima, Guillaume Vares, Yasuharu Ninomiya, Bing Wang, Takanori Katsube, Kaoru Tanaka, Kouichi Maruyama, and Mitsuru Nenoi
    • Organizer
      国際ガーリックシンポジウム
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 極限環境に耐える動物クマムシから切り拓く新たな耐性メカニズム2019

    • Author(s)
      *國枝武和
    • Organizer
      第2回理研科学者会議セミナー
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 宇宙にも耐える!極限環境に耐える動物クマムシのサバイバル戦略を読み解く2019

    • Author(s)
      *國枝武和
    • Organizer
      第635回高崎研オープンセミナー
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Plant and fish growth and nitrogen flow in aquaponics integrated with lettuce hydroponics and loach aquaculture in vertical farming2019

    • Author(s)
      *Yoshiaki Kitaya, Yotsuba Shimakawa, Teruo Wada, Toshio Shibuya, Ryosuke Endo, Masumi Kikuch, Kenji Nakamura
    • Organizer
      VertiFarm2019: Workshop on vertical farming
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 宇宙での食料生産・物質循環・健康維持機能を担う植物システムの構築2019

    • Author(s)
      北宅善昭
    • Organizer
      宇宙での食料生産・物質循環・健康維持機能を担う植物システムの構築「第4回探査の将来を考える勉強会」
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Visualization of Homeostatic Disturbances in Space2019

    • Author(s)
      *Asako Sakaue-Sawano and Atsushi Miyawaki
    • Organizer
      Resonance Bio International Symposium (RBIS)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Why do we fall asleep when bored - The gating of sleep by motivated behavior2019

    • Author(s)
      Michael Lazarus
    • Organizer
      The 10th IBRO World Congress of Neuroscience
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Evolutionary analysis of UL7 phosphorylation events encoded by a-herpesviruses2019

    • Author(s)
      Misato Shibazaki, Akihisa Kato, Jumpei Ito, Mai Suganami, Kosuke Takeshima, Yuhei Maruzuru, Naoto Koyanagi, Jun Arii, Kei Sato and Yasushi Kawaguchi
    • Organizer
      第18回あわじしま感染症・免疫フォーラム
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 長期有人宇宙活動を支える植物2019

    • Author(s)
      北宅善昭
    • Organizer
      日本植物学会第83回大会 シンポジウム「宇宙から識る植物科学」
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Plant Factories Aiming at Recycling Material and Effectively Using Energy2019

    • Author(s)
      Yoshiaki, Kitaya, Ryosuke Endo, Katsumi Ohyama
    • Organizer
      2019 China Protected Agricultural Industry Conference & 2019 International Symposium on Environment Control Technology for Value-added Plant Production
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 極限環境に耐える動物クマムシの耐性戦略2019

    • Author(s)
      國枝武和
    • Organizer
      第38回分子病理研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 単純ヘルペスウイルスの増殖・病態発現機構2019

    • Author(s)
      川口寧
    • Organizer
      第33回ヘルペスウイルス研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Development of plant-based regenerative life support systems with sweetpotato culture in space2019

    • Author(s)
      Yoshiaki, Kitaya, Kengo Higashi, Toshio Shibuya, Ryosuke Endo
    • Organizer
      32nd International symposium on space technology and science (ISTS)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Tricks enabling extremotolerance of tardigrades2019

    • Author(s)
      國枝武和
    • Organizer
      The MFPL international seminar
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Molecular Mechanisms of Herpes Simplex Virus Replication and Pathogenicity2019

    • Author(s)
      Yasushi Kawaguchi
    • Organizer
      HARVARD MEDICAL SCHOOL Special Seminar
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of Space Pant Factories in Controlled Ecological Life Support Systems2019

    • Author(s)
      Yoshiaki, Kitaya
    • Organizer
      40th Annual Meeting of the International Society for Gravitational Physiology (ISGP) and Space Life Science and Medicine Meeting
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 新しい溶液内区画化法を用いた「膜なし型」分子ロボットの提案2019

    • Author(s)
      Masahito Hayashi, Naoki Nakatani, Hiroki Sakuta, Shunsuke Tanaka, Kingo Takiguchi, Kanta Tsumoto, Kenichi Yoshikawa
    • Organizer
      第2回分子ロボティクス年次大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] TRPC6 plays a critical role in phenotype switching of vascular smooth muscle cells by physical and functional coupling with PTEN via membrane potential2019

    • Author(s)
      冨田 拓郎
    • Organizer
      第92回日本薬理学会年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Importance of receptor-activated Ca2+ influx in wound healing2019

    • Author(s)
      冨田 拓郎
    • Organizer
      第9回アジア・オセアニア生理学会連合大会(FAOPS2019)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Physiological and pathophysiological significance of TRPC3-Nox2 coupling in the heart2019

    • Author(s)
      冨田 拓郎
    • Organizer
      第9回アジア・オセアニア生理学会連合大会(FAOPS2019)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Towards spatial and temporal control of gene knockout: transgenic approaches2019

    • Author(s)
      Koichi Kawakami
    • Organizer
      The 8th Strategic Conference of Zebrafish Investigators
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 大規模マウス睡眠ステージ解析のための深層学習モデルの開発2019

    • Author(s)
      山部 剛士, 堀江 和正, 塩川 浩昭, 柳沢 正史, 北川 博之
    • Organizer
      第11回データ工学と情報マネジメントに関するフォーラム(DEIM2019)
    • Related Report
      2018 Annual Research Report
  • [Presentation] 哺乳類中枢概日時計の神経メカニズム2019

    • Author(s)
      三枝理博
    • Organizer
      明治大学現象数理学共同研究集会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Analysis of the central circadian clock in AVP neuron-specific VGAT deficient mice2019

    • Author(s)
      前島隆司, 長谷川恵美, 津野祐輔, 三枝理博
    • Organizer
      第9回アジア・オセアニア生理学会連合(FAOPS)2019年大会
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 敵対的生成ネットワークを用いたマウスEEGのノイズ削減手法の提案2019

    • Author(s)
      住谷 雄樹, 堀江 和正, 塩川 浩昭, 北川 博之
    • Organizer
      第11回データ工学と情報マネジメントに関するフォーラム(DEIM2019)
    • Related Report
      2018 Annual Research Report
  • [Presentation] PAI-1 is crucial in osteoblastic differentiation of mesenchymal stem cells.2019

    • Author(s)
      Yoshimasa Takafuji, Kohei Tatsumi, Masayoshi Ishida, Naoyuki Kawao, Kiyotaka Okada, Osamu Matsuo, Hiroshi Kaji
    • Organizer
      9th Federation of the Asian and Oceanian Physiological Societies
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Roles of macrophages and PAI-1 in diabetic delayed bone repair in female mice.2019

    • Author(s)
      Naoyuki Kawao, Takeshi Shimoide, Yukinori Tamura, Kiyotaka Okada, Katsumi Okumoto, Shinji Kurashimo, Yoshitaka Horiuchi, Kohei Tatsumi, Osamu Matsuo, Hiroshi Kaji
    • Organizer
      9th FAOPS Congress in conjunction with The 96th Annual Meeting of the Physiological Society of Japan
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Dominantly expressed Serpina3n suppresses the phenotypes of osteoblasts of female mice.2019

    • Author(s)
      Masayoshi Ishida,Naoyuki Kawao,Kiyotaka Okada,Kohei Tatsumi,Kazuko Sakai,KazutoNishio,Hiroshi Kaji
    • Organizer
      9th FAOPS Congress in conjunction with The 96th Annual Meeting of the Physiological Society of Japan
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] PAI-1は間葉系幹細胞から骨芽細胞への分化過程に重要である2019

    • Author(s)
      高藤義正、辰巳公平、石田昌義、河尾直之、岡田清孝、松尾理、梶博史
    • Organizer
      第18回日本再生医療学会総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Fos expression in the hypothalamic nuclei after changes from hypergravity to normal gravity in mice2019

    • Author(s)
      Yoichi Ueta, Mitsuhiro Yoshimura, Satomi Sonoda, Takashi Maruyama, Chikara Abe, Hironobu Morita
    • Organizer
      9th FAOPS Congress in conjunction with The 96th Annual Meeting of the Physiological Society of Japan
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Impact of long-term stay in micro-gravity on vestibular function2019

    • Author(s)
      Hironobu Morita, Chikara Abe, Kunihiko Tanaka
    • Organizer
      9th FAOPS Congress in conjunction with The 96th Annual Meeting of the Physiological Society of Japan
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 重力変化後のマウス視床下部摂食関連ペプチド遺伝子発現の変化2019

    • Author(s)
      園田里美、吉村充弘、橋本弘史、眞田賢哉、西村和朗、西村春来、田中健太郎、上野啓通、丸山 崇、安部 力、森田啓之、上田陽一
    • Organizer
      第14回環境生理学プレコングレス
    • Related Report
      2018 Annual Research Report
  • [Presentation] 前庭系を介する自律神経調節2019

    • Author(s)
      安部 力
    • Organizer
      第1回日本医学会連合「Rising Star」リトリート
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 急速輸液投与による血液希釈を伴う循環血液量増加が頭蓋内圧に与える影響2019

    • Author(s)
      倉住拓弥、小川洋二郎、田子智晴、加藤智一、小西透、岩﨑賢一
    • Organizer
      第46回日本集中治療医学会学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 遠心人工重力装置を用いた過重力環境曝露時の脳血流と脳内酸素飽和度の変化2019

    • Author(s)
      小西透、倉住拓弥、加藤智一、田子智晴、柳田亮、小川洋二郎、岩﨑賢一
    • Organizer
      第89回日本衛生学会学術総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 特別講演「宇宙医学 ~心と体の変化を探る~」2019

    • Author(s)
      小川洋二郎
    • Organizer
      第130回 日本心身医学会関東地方会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 前庭障害モデルマウスを用いた前庭機能の解析2019

    • Author(s)
      押野玲奈、大神信孝、李香、He Tingchao、加藤昌志
    • Organizer
      第89回日本衛生学会学術総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 生体サンプル中のヒ素レベルと聴力異常の関連2019

    • Author(s)
      大神信孝、李香、Xu Huadong、He Tingchao、加藤昌志
    • Organizer
      第89回日本衛生学会学術総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 生体サンプル中の鉄レベルと聴力異常の相関解析2019

    • Author(s)
      He Tingchao、大神信孝、李香、Xu Huadong、加藤昌志
    • Organizer
      第89回日本衛生学会学術総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 可聴域の騒音ストレスによるラセン神経節への影響2019

    • Author(s)
      大神信孝、He Tingchao、Xu Huadong、押野玲奈、李香、加藤昌志
    • Organizer
      第89回日本衛生学会学術総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 音楽に含まれる音成分と平衡感覚の関連2019

    • Author(s)
      Xu Huadong、大神信孝、He Tingchao、李香、武田湖州恵、加藤昌志
    • Organizer
      第89回日本衛生学会学術総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 延髄C1ニューロンを介する急性腎不全の軽減効果2019

    • Author(s)
      安部 力
    • Organizer
      第21回UTPシンポジウム
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 宇宙放射線研究におけるGatewayへの期待2019

    • Author(s)
      高橋昭久,日出間純,保田浩志
    • Organizer
      国際宇宙探査ワークショップ
    • Related Report
      2018 Annual Research Report
  • [Presentation] 低酸素環境下で発現上昇する新規低酸素誘導性分泌タンパク質HISP2はがん細胞の放射線抵抗性を誘導する2019

    • Author(s)
      諏訪達也、小林稔、原田浩
    • Organizer
      第21回菅原・大西記念癌治療増感シンポジウム
    • Related Report
      2018 Annual Research Report
  • [Presentation] 放射線に対する強さ・弱さの個人差を決める遺伝子変化の探索2019

    • Author(s)
      宮本達雄、冨岡啓太、阿久津シルビア夏子、松浦伸也
    • Organizer
      ふくしま県民公開大学
    • Related Report
      2018 Annual Research Report
  • [Presentation] 宇宙での微小重力環境におけるガンの進行2019

    • Author(s)
      高橋昭久
    • Organizer
      第33回宇宙環境利用シンポジウム
    • Related Report
      2018 Annual Research Report
  • [Presentation] 植物における宇宙での微小重力と模擬太陽光の複合影響研究2019

    • Author(s)
      日出間純,高橋昭久
    • Organizer
      第33回宇宙環境利用シンポジウム
    • Related Report
      2018 Annual Research Report
  • [Presentation] Increased chromosome aberrations in cells exposed simultaneously to simulated microgravity and radiation.2019

    • Author(s)
      Rhone JR, Beitman A, Ikeda H, Souda H, Yoshida Y, Held KD, Fujiwara K, Takahashi A, Saganti PB, Hada M.
    • Organizer
      2019 NASA Human Research Program Investigators' Workshop
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 分子腫瘍学・構造生物学・理論化学・臨床医学の融合によるがんの悪性進展制御因子に対するドラッグデザイン研究2019

    • Author(s)
      原田浩
    • Organizer
      日本医療研究開発機構(AMED) 平成30年度 創薬基盤推進研究事業公開シンポジウム-創薬のための基盤技術研究の推進と産学官連携の必要性-
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Relationship between endogenous ROS accumulation and mitochondria responses under low dose rate irradiation.2019

    • Author(s)
      Kobayashi J, Kawamura K, Qi F, Meng Q, Komatsu K.
    • Organizer
      The 3rd International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Generation of NBS1 I171V knock-in mice using genome editing technology2019

    • Author(s)
      Tatsuo Miyamoto, Keita Tomioka, Silvia Natsuko Akutsu, Hiroshi Tauchi, Shinya Matsuura
    • Organizer
      The 3rd International Symposium of the Next network-type Joint Usage / Research Center for Radiation Disaster Medical Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 宇宙での物質循環型植物工場2019

    • Author(s)
      北宅善昭
    • Organizer
      日本宇宙航空環境医学会の宇宙基地医学研究会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Towards Decryption and Application of Tardigrades' resilience mechanisms.2019

    • Author(s)
      國枝武和
    • Organizer
      エンジニアリングネットワーク・ワークショップ
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 閉鎖生態系生命維持システムにおける有力栽培作物候補であるサツマイモ2019

    • Author(s)
      北宅善昭
    • Organizer
      第33回 宇宙環境利用シンポジウム 一般セッション
    • Related Report
      2018 Annual Research Report
  • [Presentation] Gateway研究例紹介:生態工学の観点から2019

    • Author(s)
      北宅善昭・桜井誠人
    • Organizer
      第33回 宇宙環境利用シンポジウム 深宇宙探査ゲートウェイ計画セッション
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Gateway研究例紹介:生態工学2019

    • Author(s)
      北宅善昭
    • Organizer
      将来月探査ワークショップ―HERACLES・Gatewayの活用―
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 宿主免疫による単純ヘルペスウイルスの認識機構とウイルスによる免疫回避機構2019

    • Author(s)
      川口 寧
    • Organizer
      第12回次世代アジュバント研究会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] ヒトの免疫から逃れる厄介なウイルスのお話し2019

    • Author(s)
      川口 寧
    • Organizer
      北海道大学人獣共通感染症リサーチセンター市民公開講座「感染症の克服に向けて」
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 網羅的遺伝子発現解析結果に基づく膵β細胞障害メカニズムの解明.2019

    • Author(s)
      西村 渉
    • Organizer
      岡山大学医歯学総合研究科大学院特別セミナー
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 国際宇宙ステーションにおける超高濃度CO2環境下での植物の生育改善2019

    • Author(s)
      古市卓也、松波志帆、加藤彩、中澤映李加、長尾由依、藤田博子
    • Organizer
      第60回日本植物生理学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] オプトジェネティクス酸化ストレス誘導法による筋萎縮メカニズムの解明と治療薬探索Elucidation of muscle atrohpy mechanism by optogenetic oxidative stress induction method for screening of therapeutic drugs.2018

    • Author(s)
      Fuminori Sato
    • Organizer
      先進ゲノム解析研究推進プラットフォーム(先進ゲノム支援)拡大班会議
    • Related Report
      2018 Annual Research Report
  • [Presentation] Impacts of space flight and its ground models on the thymus2018

    • Author(s)
      Kenta Horie, Takao Seki, Nobuko Akiyama, Tamotsu Kato, , Hiroshi Ohno, Satoru Takahashi, and Taishin Akiyama
    • Organizer
      第47回日本免疫学会学術総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Dependency of thymic dendritic cell maturation on RANK and CD40 signaling2018

    • Author(s)
      Takao Seki, Kenta Horie, Nobuko Akiyama, Taishin Akiyama
    • Organizer
      第47回日本免疫学会学術総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Cell-Sized Aqueous/Aqueous Microdroplets: Compartments for Biomacromolecular Assembly Emerging through Micro-Phase Separation2018

    • Author(s)
      K. Tsumoto, H. Sakuta, M. Tomita, K. Takiguchi, K. Yoshikawa
    • Organizer
      12th International Symposium on Nanomedicine (ISNM2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Monitoring of Calcium Ion Permeation Using Single GUVs Prepared with the Droplet Transfer Method2018

    • Author(s)
      Y. Uno, M. Nishigami, M. Tomita, K. Tsumoto
    • Organizer
      12th International Symposium on Nanomedicine (ISNM2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Specific localization of living cells in water/water microdroplets toward the spontaneous generation of 3D cell-assembly: Experiments with red blood cells and NAMRU mouse mammary gland epithelial cells2018

    • Author(s)
      Y. Hoda, T. Fujimoto, K. Yoshikawa, K. Tsumoto
    • Organizer
      29th 2018 IEEE International Symposium on Micro-NanoMechatronics and Human Science (MHS 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Direct observation of chondrocytes under high hydrostatic pressure2018

    • Author(s)
      M. Morimatsu, A. Fujita, M. Nishiyama, K. Naruse
    • Organizer
      ASCB 2018 米国細胞生物学会議
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Mechanical stress modulates the homeostasis of periodontal ligament2018

    • Author(s)
      Ayano Fujita, Masatoshi Morimatsu, Masayoshi Nishiyama, Shogo Takashiba, Keiji Naruse
    • Organizer
      ASCB 2018 米国細胞生物学会議
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Study on gravity-dependent skeletal muscle maintenance mechanisms using Zebrafish, aquatic organisms2018

    • Author(s)
      Fuminori Sato, Minyong Choi, Zi Wang, Kiyomi Imamura, Terumi Horiuchi, Wu Quan, Ikumi Fujita, Satoko Uchida, Mitsuyasu Kato, Fumiaki Tanigaki, Akira Higashibata, Masafumi Muratani, Junya Kobayashi, Akihisa Takahashi, Sumio Sugano, Fumio Matsuzaki, Yutaka Suzuki, Koichi Kawakami, Atsuko Sehara-Fujisawa
    • Organizer
      2018 ASCB EMBO Meeting
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 新規運動耐性改善候補薬の標的因子探索2018

    • Author(s)
      矢島大聖、松本健、田中敦、小椋利彦
    • Organizer
      第41回日本分子生物学会年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Self-Emergence of Cell-Like Structure of Actin and DNA in Cell-Sized Aqueous/Aqueous Micro Droplets2018

    • Author(s)
      Hiroki Sakuta, Kingo Takiguchi, Kanta Tsumoto, Kenichi Yoshikawa
    • Organizer
      International Conference on Advances in Physics of Emergent orders in Fluctuations (APEF 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 微小重力環境下でのエピジェネティクスによる骨格筋制御因子の探索2018

    • Author(s)
      坪内鴻奈、岡田理沙、鈴木 陸、布施谷清香、林 卓杜、中村勇輝、久野朗広、村谷匡史、工藤 崇、高橋 智
    • Organizer
      第41回日本分子生物学会年会
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ユビキチンリガーゼCbl-bは無重力ストレス誘導性の酸化ストレスにより増大する2018

    • Author(s)
      三木裕加里、内田貴之、木森有希、坂下禎宏、小松明生、真板綾子、内田実佑、藤岡大樹、小林剛、東谷篤志、石原直忠、東端晃、石岡憲昭、武田伸一、曽我部正博、二川健
    • Organizer
      第51回 日本栄養・食糧学会 中国・四国支部大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Cbl-b阻害ペプチド高含有米の除神経性筋萎縮改善作用の評価2018

    • Author(s)
      佐藤友紀、中尾玲子、赤間一仁、二川健
    • Organizer
      第51回 日本栄養・食糧学会 中国・四国支部大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Unloadingストレスに対する筋細胞の初期応:酸化ストレスの重要性2018

    • Author(s)
      二川健、内田貴之、中尾玲子、平坂勝也、真板宣夫、東谷篤志、小林剛、石原直忠、曽我部正博
    • Organizer
      第41回日本分子生物学会年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 線虫の運動に対する放射線影響とその回復におけるオートファジーの関与2018

    • Author(s)
      渡辺 尚、森松 賢順、西山 雅祥、渡邉 賢、鍵 裕之、成瀬 恵治、東谷 篤志
    • Organizer
      日本放射線影響学会第61回大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 線虫を用いた筋ミトコンドリア研究2018

    • Author(s)
      東谷 篤志、小林 剛
    • Organizer
      第41回 日本分子生物科学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Unloadingストレスに対する筋細胞の初期応答: 酸化ストレスの重要性2018

    • Author(s)
      二川 健、内田 貴之、中尾 玲子、平坂 克也、真板 宣夫、東谷 篤志、小林 剛、石原 直忠、曽我部 正博
    • Organizer
      第41回 日本分子生物科学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] ゼブラフィッシュ宇宙滞在実験から微小重力の骨格筋への影響とそのメカニズムを探るExploring the effect of microgravity on skeletal muscle and its mechanism from the space experiment using zebrafish2018

    • Author(s)
      佐藤文規、Choi Minyong、王梓、今村聖実、堀内映美、呉 泉、藤田 生水、内田智子、加藤 充康、谷垣文章、東端 晃、村谷匡史、小林純也、高橋昭久、菅野純夫、松崎 文雄、鈴木穣、川上浩一、瀬原淳子
    • Organizer
      第41回日本分子生物学会年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] アクチン結合タンパク質Lima1を用いたFRET張力センサーの開発2018

    • Author(s)
      平野咲雪、山元孝佳、道上達男
    • Organizer
      第41回日本分子生物学会年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 国際宇宙ステーションにおけるマウス実験2018

    • Author(s)
      高橋 智
    • Organizer
      IETセミナー(東京)
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 静水圧負荷による軟骨細胞の圧力受容応答メカニズムの解明2018

    • Author(s)
      寺町一希, 森松賢順, 藤田彩乃, 西山雅祥, 成瀬恵治
    • Organizer
      第41回日本生体医工学会中国四国支部大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] ゼブラフィッシュにおけるトランスポゾンを用いたゲノムワイド遺伝子トラップスクリーンと脳機能研究への応用2018

    • Author(s)
      川上浩一
    • Organizer
      第91回日本生化学会大会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Response to physical force in C. elegans2018

    • Author(s)
      Atsushi Higashitani
    • Organizer
      日本生物物理学会第56回年会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Spaceflight experiments using the nematode C. elegans2018

    • Author(s)
      Atsushi Higashitani
    • Organizer
      The 15th Korea-Japan Joint Seminar on Space Environment Utilization Research
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 線虫の物理的力に対する応答2018

    • Author(s)
      東谷篤志
    • Organizer
      日本生物物理学会第56回年会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] A Mission Report on: Nematode Muscles Project in Spaceflight Experiment.2018

    • Author(s)
      Sudevan S, Hashizume T, Yano S, Kuriyama K, Momma K, Harada S, Umehara M, Higashibata A, Higashitani A.
    • Organizer
      日本宇宙生物科学会第32回大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 微小重力はドーパミンによる神経伝達に影響を及ぼすのか2018

    • Author(s)
      橋爪藤子、梅原真澄、東端晃、東谷なほ子、東谷篤志
    • Organizer
      日本宇宙生物科学会第32回大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] A Mission Report on: Epigenetics Project in C. elegans Spaceflight.2018

    • Author(s)
      Higashitani A, Hashizume T, Takiura M, Yano S, Kuriyama K, Umehara M, Higahibata A.
    • Organizer
      日本宇宙生物科学会第32回大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 骨格筋維持における重力の役割-ゼブラフィッシュの宇宙滞在から学ぶ事Roles of the gravity in the maintenance of skeletal muscle ? what we can learn from space stay of zebrafish2018

    • Author(s)
      瀬原 淳子
    • Organizer
      第56回日本生物物理学会年会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Space stay of zebrafish2018

    • Author(s)
      Atsuko Sehara
    • Organizer
      The 15th Korea-Japan Joint Seminar on Space Environment Utilization Research
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 人工重力発生装置を用いたゼブラフィッシュ宇宙滞在実験2018

    • Author(s)
      佐藤文規, Choi Minyong, 王梓, 今村聖実, 堀内映美, 呉泉, 藤田生水, 内田智子, 加藤充康, 谷垣文章, 東端晃, 村谷匡史, 小林純也, 高橋昭久, 菅野純夫, 松崎文雄, 鈴木穣, 川上浩一, 瀬原淳子
    • Organizer
      宇宙生物科学会第32回大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Acute transcriptional control specific to osteoblasts/osteoclasts in medaka fish immediately after exposure to microgravity2018

    • Author(s)
      Masahiro Chatani
    • Organizer
      15th Korea-Japan Joint Seminar on Space Environment Utilization Research
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Effects of gravity change on medaka fish hard tissues2018

    • Author(s)
      Masahiro Chatani, Aiko Mitsuhashi, Yusuke Dodo, Yuki Azetsu, Nobuhiro Sakai, Akira Kudo, Masamichi Takami
    • Organizer
      29th Australian and New Zealand Bone and Mineral Society (ANZBMS) ANNUAL SCIENTIFIC MEETING
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Toward the Elucidation of Cell Gravi-Sensing in Space.2018

    • Author(s)
      Masahiro SOKABE, Takeshi Kobayashi, Takeshi Nikawa, Keiji Naruse, Akira Higashibata
    • Organizer
      the 15th Korea-Japan Joint Seminar on Space Environment Utilization Research
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 間葉系幹細胞の重力感知における機械刺激受容チャンネルTRPV4を介したシグナル伝達経路の役割2018

    • Author(s)
      加藤信靖, 田中瑞奈, 曽我部正博, 小林 剛
    • Organizer
      日本宇宙生物科学会第32回大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 生細胞の細胞膜上での機械刺激受容チャンネルTRPV4の動態の解析2018

    • Author(s)
      堀池由朗, 田中瑞奈, 加藤信靖, 成瀬恵治, 曽我部正博, 小林 剛
    • Organizer
      日本宇宙生物科学会第32回大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Giant vesicles rapidly prepared and purified using a reverse-phase/centrifugation method2018

    • Author(s)
      Kanta Tsumoto, Kohei Nakano, Yuki Hayashi, Masahiro Tomita
    • Organizer
      第56回日本生物物理学会年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Spatial Cooperation between DNA and Actin in Micro-Confinement Generated throughSpontaneous Phase Segregation2018

    • Author(s)
      Hiroki Sakuta, Naoki Nakatani, Masahito Hayashi, Kingo Takiguchi, Kanta Tsumoto,Kenichi Yoshikawa
    • Organizer
      第56回日本生物物理学会年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 界面通過法により作製したGUVによるカルシウムイオン膜透過性評価2018

    • Author(s)
      宇野勇気,西上美佐子,冨田昌弘,湊元幹太
    • Organizer
      第91回日本生化学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Regulatory mechanism of root hydrotropism for water acquisition in arid environment2018

    • Author(s)
      Hideyuki Takahashi
    • Organizer
      International Symposium on Plant Survival Strategies in Extreme Environment at 32nd Annual Meeting of the Japanese Society for Biological Sciences in Space
    • Related Report