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Integrative Research toward Elucidation of Generative Brain Systems for Individuality

Administrative Group

Project AreaIntegrative research toward elucidation of generative brain systems for individuality
Project/Area Number 16H06524
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionTohoku University

Principal Investigator

Osumi Noriko  東北大学, 医学系研究科, 教授 (00220343)

Co-Investigator(Kenkyū-buntansha) 冨永 貴志  徳島文理大学, 神経科学研究所, 教授 (20344046)
保前 文高  東京都立大学, 人文科学研究科, 准教授 (20533417)
若林 明雄  千葉大学, 大学院人文科学研究院, 教授 (30175062)
柴田 智広  九州工業大学, 大学院生命体工学研究科, 教授 (40359873)
郷 康広  大学共同利用機関法人自然科学研究機構(新分野創成センター、アストロバイオロジーセンター、生命創成探究, 生命創成探究センター, 特任准教授 (50377123)
今吉 格  京都大学, 生命科学研究科, 教授 (60543296)
駒木 文保  東京大学, 大学院情報理工学系研究科, 教授 (70242039)
星野 幹雄  国立研究開発法人国立精神・神経医療研究センター, 神経研究所 病態生化学研究部, 部長 (70301273)
原 塑  東北大学, 文学研究科, 准教授 (70463891)
中島 欽一  九州大学, 医学研究院, 教授 (80302892)
Project Period (FY) 2016-06-30 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥123,760,000 (Direct Cost: ¥95,200,000、Indirect Cost: ¥28,560,000)
Fiscal Year 2020: ¥22,230,000 (Direct Cost: ¥17,100,000、Indirect Cost: ¥5,130,000)
Fiscal Year 2019: ¥22,230,000 (Direct Cost: ¥17,100,000、Indirect Cost: ¥5,130,000)
Fiscal Year 2018: ¥22,230,000 (Direct Cost: ¥17,100,000、Indirect Cost: ¥5,130,000)
Fiscal Year 2017: ¥22,230,000 (Direct Cost: ¥17,100,000、Indirect Cost: ¥5,130,000)
Fiscal Year 2016: ¥34,840,000 (Direct Cost: ¥26,800,000、Indirect Cost: ¥8,040,000)
Keywords個性 / パーソナリティ / 脳内基盤 / 動物モデル / 発生発達過程 / 多様性 / 数理モデル / データシェアリングプラットフォーム / 脳科学 / 基盤 / 社会脳科学 / 脳計測科学 / 基板・社会脳科学 / 脳科学 基盤 / 社会脳科学 脳計測科学 / 基盤・社会脳科学 / 神経基盤
Outline of Final Research Achievements

In this research area, we aimed to understand "individuality" objectively and scientifically, and in Group A01, we attempted to elucidate the brain basis for the expression of individuality in behavior, cognition, and personality, mainly in humans from infant to adult. In Group A02, we aimed to understand the mechanism of the emergence of "individuality" by focusing on phenotypes such as increased or decreased diversity as an effect of various interventions, such as genome editing and maternal drug exposure, on individuals during gametogenesis and development using laboratory animals such as rodents. In Group A03, we developed various analytic systems and devices, provided technologies, and constructed mathematical models. The above activities were promoted through the establishment of an international data sharing platform.

Academic Significance and Societal Importance of the Research Achievements

本領域では、研究成果の社会的還元をより一層意識して研究を進めるために、領域ウェブサイトにおける発信を頻度高く行うとともに、一般市民も対象とするニュースレターを年2回発行し、研究者や市民に配布した。さらに、計3回の市民公開講演会を開催して、第1回講演会の内容を基盤とした書籍を2020年に岩波書店より刊行し、第2回講演会の内容をもとに、ちくまプリマー新書を2021年6月に刊行予定としている。「個性」を人文社会学、生物学、理工学の様々な視点から科学的に理解し、共有することを目指す本領域全体を取りまとめた成果の発信として、2021年8月に朝倉書店より『個性学入門:個性創発の科学』を刊行する。

Report

(6 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (229 results)

All 2021 2020 2018 2017 2016 Other

All Int'l Joint Research (6 results) Journal Article (72 results) (of which Int'l Joint Research: 27 results,  Peer Reviewed: 72 results,  Open Access: 53 results,  Acknowledgement Compliant: 2 results) Presentation (135 results) (of which Int'l Joint Research: 42 results,  Invited: 69 results) Book (10 results) Remarks (6 results)

  • [Int'l Joint Research] チュラロンコーン大学(タイ)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] IIIT-Delhi(インド)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] エディンバラ大学(英国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] トロント・マウントサイナイ病院/フレフェルドタネンバウム研究所/トロント大学(カナダ)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] ウッズホール海洋生物学研究所(米国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2020 Annual Research Report
  • [Journal Article] Paternal age affects offspring via an epigenetic mechanism involving REST/NRSF.2021

    • Author(s)
      Yoshizaki Kaichi, Kimura Ryuichi, Kobayashi Hisato, Oki Shinya, Kikkawa Takako, Mai Lingling, Koike Kohei, Mochizumi Kentaro, Inada Hitoshi, Matsui Yasuhisa, Kono Tomohiro, Osumi Noriko
    • Journal Title

      EMBO Reports

      Volume: 22(2) Issue: 2

    • DOI

      10.15252/embr.202051524

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prefrontal synaptic activation during hippocampal memory reactivation2021

    • Author(s)
      Yuya Nishimura , Yuji Ikegaya , Takuya Sasaki
    • Journal Title

      Cell Reports

      Volume: 34(12) Issue: 12 Pages: 108885-108885

    • DOI

      10.1016/j.celrep.2021.108885

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prioritized experience replays on a hippocampal predictive map for learning2021

    • Author(s)
      Hideyoshi Igata, Yuji Ikegaya , Takuya Sasaki
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 118(1) Issue: 1

    • DOI

      10.1073/pnas.2011266118

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Narcissism in independent and interdependent cultures2021

    • Author(s)
      Jauk,E., Breyer, D., Kanske, P., & Wakabayashi, A
    • Journal Title

      Personality and Individual Differences

      Volume: 177 Pages: 110716-110716

    • DOI

      10.1016/j.paid.2021.110716

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Perirhinal cortex area 35 controls the functional link between the perirhinal and entorhinal‐hippocampal circuitry.2021

    • Author(s)
      Kajiwara R, Tominaga T
    • Journal Title

      Bioessays

      Volume: 43 Issue: 3 Pages: 2000084-2000084

    • DOI

      10.1002/bies.202000084

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A Functional Aqp1 Gene Product Localizes on The Contractile Vacuole Complex in Paramecium multimicronucleatum2021

    • Author(s)
      Masaki Ishida, Manabu Hori, Yui Ooba, Masako Kinoshita, Tsuyoshi Matsutani, Musumi Naito, Taeko Hagimoto, Kuniko Miyazaki, Sou Ueda, Ken Miura, Takashi Tominaga
    • Journal Title

      Journal of Eukaryotic Microbiology

      Volume: - Issue: 3 Pages: 1-11

    • DOI

      10.1111/jeu.12843

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Sex differences in the effects of prenatal bisphenol A exposure on autism-related genes and their relationships with the hippocampus functions2021

    • Author(s)
      Thongkorn Surangrat、Kanlayaprasit Songphon、Panjabud Pawinee、Saeliw Thanit、Jantheang Thanawin、Kasitipradit Kasidit、Sarobol Suthathip、Jindatip Depicha、Hu Valerie W.、Tencomnao Tewin、Kikkawa Takako、Sato Tatsuya、Osumi Noriko、Sarachana Tewarit
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1

    • DOI

      10.1038/s41598-020-80390-2

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMPSmad signaling2021

    • Author(s)
      Nakashima H., Tsujimura K., Irie K., Imamura T., Trujillo CA., Ishizu M., Uesaka M., Pan M., Noguchi H., Okada K., Aoyagi K., Andoh-Noda T., Okano H., Murotri AR., Nakashima K.
    • Journal Title

      Cell Reports

      Volume: -

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] SoxE group transcription factor Sox8 promotes astrocytic differentiation of neural stem/precursor cells downstream of Nfia2021

    • Author(s)
      Takouda J., Katada S., Imamura T. and Nakashima K.
    • Journal Title

      Pharmacology Research & Perspectives

      Volume: - Issue: 6

    • DOI

      10.1002/prp2.749

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Reconstitution of the oocyte transcriptional network with transcription factors2021

    • Author(s)
      Hamazaki N, Kyogoku H, Araki H, Miura F, Horikawa C, Hamada N, Shimamoto S, Hikabe O, Nakashima K, Kitajima TS, Ito T, Leitch HG, Katsuhiko Hayashi.
    • Journal Title

      Nature

      Volume: 589 Issue: 7841 Pages: 883-897

    • DOI

      10.1038/s41586-020-3027-9

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] MacaquePose: a novel ‘in the wild’ macaque monkey pose dataset for markerless motion capture.2021

    • Author(s)
      Labuguen RT, Matsumoto J, Negrete SB, Nishimaru H, Nishijo H, Takada M, Go Y, Inoue K, Shibata T
    • Journal Title

      Front Behav Neurosci

      Volume: 14 Pages: 581154-581154

    • DOI

      10.3389/fnbeh.2020.581154

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Notch Signaling between Cerebellar Granule Cell Progenitors2021

    • Author(s)
      Adachi T, Miyashita S, Yamashita M, Shimoda M, Okonechnikov K, Chavez L, Kool M, Pfister SM, Inoue T, Kawauchi D, Hoshino M.
    • Journal Title

      eNeuro.

      Volume: 0468-20

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Potential involvement of DSCAML1 mutations in neurodevelopmental disorders2021

    • Author(s)
      Ogata S, Hashizume K, Hayase Y, Kanno Y, Hori K, Balan S, Yoshikawa T, Takahashi H, Taya S, Hoshino M
    • Journal Title

      Genes Cells

      Volume: (3) Issue: 3 Pages: 136-151

    • DOI

      10.1111/gtc.12831

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Performance Evaluation of Markerless 3D Skeleton Pose Estimates with Pop Dance Motion Sequence2021

    • Author(s)
      Labuguen,R.,Blanco, N.S.,Kogami, T.,Ingco, W,E,M., Shibata, T.
    • Journal Title

      IEEE Explore

      Volume: - Pages: 1-7

    • DOI

      10.1109/icievicivpr48672.2020.9306581

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] DSCAM regulates delamination of neurons in the developing midbrain2020

    • Author(s)
      Arimura Nariko、Okada Mako、Taya Shinichiro、Dewa Ken-ichi、Tsuzuki Akiko、Uetake Hirotomo、Miyashita Satoshi、Hashizume Koichi、Shimaoka Kazumi、Egusa Saki、Nishioka Tomoki、Yanagawa Yuchio、Yamakawa Kazuhiro、Inoue Yukiko U.、Inoue Takayoshi、Kaibuchi Kozo、Hoshino Mikio
    • Journal Title

      Science Advances

      Volume: 6 Issue: 36 Pages: 1693-1693

    • DOI

      10.1126/sciadv.aba1693

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation2020

    • Author(s)
      Kutscher LM, Okonechnikov K, Batora NV, Clark J, Silva PBG, Vouri M, van Rijn S, Sieber L, Statz B, Gearhart MD, Shiraishi R, Mack N, Orr BA, Korshunov A, Gudenas BL, Smith KS, Mercier AL, Ayrault O, Hoshino M, Kool M, von Hoff K, Graf N, Fleischhack G, Bardwell VJ, Pfister SM, Northcott PA, Kawauchi D.
    • Journal Title

      Genes Dev.

      Volume: 34(17-18) Pages: 1161-1176

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Redundant type II cadherins define neuroepithelial cell states for cytoarchitectonic robustness2020

    • Author(s)
      Hiraga Kou、Inoue Yukiko U.、Asami Junko、Hotta Mayuko、Morimoto Yuki、Tatsumoto Shoji、Hoshino Mikio、Go Yasuhiro、Inoue Takayoshi
    • Journal Title

      Communications Biology

      Volume: 3 Issue: 1 Pages: 574-574

    • DOI

      10.1038/s42003-020-01297-2

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The role of SCFSkp2 and SCFβ-TrCP1/2 in the cerebellar granule cell precursors2020

    • Author(s)
      Yamashita M, Owa T, Shiraishi R, Adachi T, Ichijo K, Taya S, Miyashita S, Hoshino M
    • Journal Title

      Genes Cells

      Volume: (12) Issue: 12 Pages: 796-810

    • DOI

      10.1111/gtc.12813

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication2020

    • Author(s)
      Yamashiro Kunihiko、Hori Kei、Lai Esther S.K.、Aoki Ryo、Shimaoka Kazumi、Arimura Nariko、Egusa Saki F.、Sakamoto Asami、Abe Manabu、Sakimura Kenji、Watanabe Takaki、Uesaka Naofumi、Kano Masanobu、Hoshino Mikio
    • Journal Title

      iScience

      Volume: 23 Issue: 12 Pages: 101820-101820

    • DOI

      10.1016/j.isci.2020.101820

    • NAID

      120006979860

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility.2020

    • Author(s)
      Hayase Y, Amano S, Hashizume K, Tominaga T, Miyamoto H, Kanno Y, Ueno-Inoue Y, Inoue T, Yamada M, Ogata S, Balan S, Hayashi K, Miura Y, Tokudome K, Ohno Y, Nishijo T, Momiyama T, Yanagawa Y, Takizawa A, Mashimo T, Serikawa T, Sekine A, Nakagawa E, Takeshita E, Yoshikawa T, Waga C, Inoue K, Goto YI, Nabeshima Y, et al.
    • Journal Title

      Acta Neuropathol Commun.

      Volume: 8 Issue: 1 Pages: 206-206

    • DOI

      10.1186/s40478-020-01082-6

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Deconvolution of calcium imaging data using marked point processes2020

    • Author(s)
      Ryohei Shibue,Fumiyasu Komaki
    • Journal Title

      PLOS Computational Biology

      Volume: 16(3) Issue: 3 Pages: e1007650-e1007650

    • DOI

      10.1371/journal.pcbi.1007650

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Birefringence Changes of Dendrites in Mouse Hippocampal Slices Revealed with Polarizing Microscopy.2020

    • Author(s)
      Maki Koike-Tani M, Takashi Tominaga, Rudolf Oldenbourg, Tomomi Tani.
    • Journal Title

      Biophys J.

      Volume: - Issue: 10 Pages: 2366-2384

    • DOI

      10.1016/j.bpj.2020.03.016

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Optogenetic Manipulation of Postsynaptic cAMP Using a Novel Transgenic Mouse Line Enables Synaptic Plasticity and Enhances Depolarization Following Tetanic Stimulation in the Hippocampal Dentate Gyrus2020

    • Author(s)
      Luyben, T., Rai, J., Li, H., Georgiou, J., Avila, A., Zhen, M., Collingridge, G., Tominaga, T., Okamoto, K.
    • Journal Title

      Frontiers in Neural Circuits

      Volume: 14 Pages: 24-24

    • DOI

      10.3389/fncir.2020.00024

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Roles of Adenylate Cyclases in Ciliary Responses of Paramecium to Mechanical Stimulation2020

    • Author(s)
      Mutsumi Kawano, Takashi Tominaga, Masaki Ishida, Manabu Hori
    • Journal Title

      Journal of Eukaryotic Microbiology

      Volume: 67 Issue: 5 Pages: 532-540

    • DOI

      10.1111/jeu.12800

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Optimization of light-inducible Gal4/UAS gene expression system in mammalian cells2020

    • Author(s)
      Yamada M., Nagasaki C. S., Suzuki Y., Imayoshi I.
    • Journal Title

      iScience

      Volume: 23 Issue: 9 Pages: 101506-101506

    • DOI

      10.1016/j.isci.2020.101506

    • NAID

      120006884197

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Light-induced silencing of neural activity in Rosa26 knock-in and BAC transgenic mice conditionally expressing the microbial halorhodopsin eNpHR3.2020

    • Author(s)
      Imayoshi I, Tabuchi S, Matsumoto M, Kitano S, Miyachi H, Kageyama R, Yamanaka A
    • Journal Title

      Sci Rep

      Volume: 10(1) Issue: 1 Pages: 3191-3191

    • DOI

      10.1038/s41598-020-59984-3

    • NAID

      120006878490

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cholecystokinin-expressing Interneurons of the Medial Prefrontal Cortex Mediate Working Memory Retrieval.2020

    • Author(s)
      Nguyen, R., Venkatesan, S., Binko, M., Yoon Bang, J., Cajanding, J.D., Briggs, C., Sargin, D., Imayoshi, I., Lambe, E.K. and Chul Kim, J.
    • Journal Title

      J Neurosci.

      Volume: 40 Issue: 11 Pages: 2314-2331

    • DOI

      10.1523/jneurosci.1919-19.2020

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Light-mediated Control of Gene Expression in Mammalian Cells.2020

    • Author(s)
      Yamada M, Nagasaki C. S, Ozawa T, Imayoshi I.
    • Journal Title

      Neuroscience Research

      Volume: 152 Pages: 66-77

    • DOI

      10.1016/j.neures.2019.12.018

    • NAID

      120006888020

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comprehensive histochemical profiles of histone modification in male germline cells during meiosis and spermiogenesis: Comparison of young and aged testes in mice2020

    • Author(s)
      Tatehana M, Kimura R, Mochizuki K, Inada H, Osumi N
    • Journal Title

      PLoS One

      Volume: eCollection 2020 Issue: 4 Pages: e0230930-e0230930

    • DOI

      10.1371/journal.pone.0230930

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression.2020

    • Author(s)
      Nakagawa T, Hattori S, Nobuta R, Kimura R, Nakagawa M, Matsumoto M, Nagasawa Y, Funayama R, Miyakawa T, Inada T, Osumi N, Nakayama KI, Nakayama K.
    • Journal Title

      iScience

      Volume: 23 Issue: 4 Pages: 101030-101030

    • DOI

      10.1016/j.isci.2020.101030

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 欠如モデル・一方向コミュニケーション・双方向コミュニケーションーー科学技術コミュニケーションにおける中核概念の再配置2020

    • Author(s)
      内田麻理香,原塑
    • Journal Title

      科学技術社会論研究

      Volume: 18 Pages: 208-220

    • NAID

      130008031940

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis2020

    • Author(s)
      Casingal Cristine R.、Kikkawa Takako、Inada Hitoshi、Sasaki Yukio、Osumi Noriko
    • Journal Title

      Molecular Brain

      Volume: 13 Issue: 1 Pages: 1-13

    • DOI

      10.1186/s13041-020-00706-1

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Bayes extended estimators for curved exponential families2020

    • Author(s)
      Michiko Okudo and Fumiyasu Komaki
    • Journal Title

      IEEE Transactions on Information Theory

      Volume: 67(2) Issue: 2 Pages: 1088-1098

    • DOI

      10.1109/tit.2020.3035027

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] AUTS2 regulation of synapses for proper synaptic inputs and social communication.2020

    • Author(s)
      Hori Kei、Yamashiro Kunihiko、Nagai Taku、... Yamada Mitsuhiko、Yamada Kiyofumi、Hoshino Mikio
    • Journal Title

      iScience

      Volume: ー Issue: 6 Pages: 101183-101183

    • DOI

      10.1016/j.isci.2020.101183

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Explicit performance in girls and implicit processing in boys: A simultaneous fNIRS-ERP study on second language syntactic learning in young adolescents.2018

    • Author(s)
      Sugiura L, Hata M, Matsuba Kurita H, Uga M, Tsuzuki D, Dan I, Hagiwara H and Homae
    • Journal Title

      Frontiers in Human Neuroscience 1

      Volume: 12 Pages: 1-12

    • DOI

      10.3389/fnhum.2018.00062

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Therapeutic time window of anti-high mobility group box-1 antibody administration in mouse model of spinal cord injury.2018

    • Author(s)
      Nakashima H, Tsujimura K, Irie K, Ishizu M, Pan M, Kameda T, Nakashima K:
    • Journal Title

      Neurosci Res

      Volume: - Pages: 63-70

    • DOI

      10.1016/j.neures.2018.03.004

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Ectopic neurogenesis induced by prenatal antiepileptic drug exposure augments seizure susceptibility in adult mice.2018

    • Author(s)
      Sakai A, Matsuda T, Doi H, Nagaishi Y, Kato K, Nakashima K
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: - Issue: 16 Pages: 4270-4275

    • DOI

      10.1073/pnas.1716479115

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Prior Treatment with Anti-High Mobility Group Box-1 Antibody Boosts Human Neural Stem Cell Transplantation-Mediated Functional Recovery After Spinal Cord Injury.2018

    • Author(s)
      Uezono N, Zhu Y, Y, Matsuda T,Nakajo M, Abematsu M, Setoguchi T, Mori S, Takahashi HK, Komiya S, Nishibori M, Nakashima K:
    • Journal Title

      Stem Cells

      Volume: - Issue: 5 Pages: 0-0

    • DOI

      10.1002/stem.2802

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] HMGB2 expression is associated with transition from a quiescent to an activated state of adult neural stem cells.2018

    • Author(s)
      Kimura A, Matsuda T, Sakai A, Murao N, Nakashima K
    • Journal Title

      Dev Dyn

      Volume: 247 Issue: 1 Pages: 229-238

    • DOI

      10.1002/dvdy.24559

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neural stem cell therapy aiming at better functional recovery after spinal cord injury.2018

    • Author(s)
      Zhu Y, Uezono N, Yasui T, Nakashima K
    • Journal Title

      Dev Dyn

      Volume: 247

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation2018

    • Author(s)
      Owa Tomoo、Taya Shinichiro、Miyashita Satoshi、Yamashita Mariko、Adachi Toma、Yamada Koyo、Yokoyama Miwa、Aida Shogo、Nishioka Tomoki、Inoue Yukiko U.、Goitsuka Ryo、Nakamura Takuro、Inoue Takayoshi、Kaibuchi Kozo、Hoshino Mikio
    • Journal Title

      The Journal of Neuroscience

      Volume: 38 Issue: 5 Pages: 1277-1294

    • DOI

      10.1523/jneurosci.1545-17.2017

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Generation of Pax6-IRES-EGFP knock-in mouse via the cloning-free CRISPR/Cas9 system to reliably visualize neurodevelopmental dynamics2018

    • Author(s)
      Inoue Yukiko U.、Morimoto Yuki、Hoshino Mikio、Inoue Takayoshi
    • Journal Title

      Neuroscience Research

      Volume: in press Pages: 1-7

    • DOI

      10.1016/j.neures.2018.01.007

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Entrainment of the Circadian Clock in Neural Stem Cells by Epidermal Growth Factor is Closely Associated with ERK1/2-mediated Induction of Multiple Clock-related Genes2018

    • Author(s)
      Mogi A, Yomoda R, Kimura S, Tsushima C, Takouda J, Sawauchi M, Maekawa T, Ohta H, Nishino S, Kurita M, Mano N, Osumi N, Moriya T
    • Journal Title

      Neuroscience

      Volume: 379 Pages: 45-66

    • DOI

      10.1016/j.neuroscience.2018.02.045

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The role of Pax6 in brain development and its impact on pathogenesis of autism spectrum disorder2018

    • Author(s)
      Kikkawa Takako、Casingal Cristine R.、Chun Seung Hee、Shinohara Hiroshi、Hiraoka Kotaro、Osumi Noriko
    • Journal Title

      Brain Research

      Volume: - Pages: 30111-2

    • DOI

      10.1016/j.brainres.2018.02.041

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adult-born neurons facilitate olfactory bulb pattern separation during task engagement.2018

    • Author(s)
      Li W, Chu MW, Wu A, Suzuki Y, Imayoshi I and Komiyama T
    • Journal Title

      eLife

      Volume: 7

    • DOI

      10.7554/elife.33006

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The effects of actual situations and the facial expressions of another person when experiencing pain on observers' understanding of the pain and sense of unpleasantness2017

    • Author(s)
      河村康佑、若林明雄
    • Journal Title

      The Japanese Journal of Cognitive Psychology

      Volume: 15 Issue: 1 Pages: 13-19

    • DOI

      10.5265/jcogpsy.15.13

    • NAID

      130006251026

    • ISSN
      1348-7264, 2185-0321
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synergistic induction of astrocytic differentiation by factors secreted from meninges in the mouse developing brain.2017

    • Author(s)
      Kawamura Y, Katada S, Noguchi H, Yamamoto H, Sanosaka T, Iihara K, Nakashima K
    • Journal Title

      FEBS lett

      Volume: 59 Issue: 22 Pages: 3709-3720

    • DOI

      10.1002/1873-3468.12881

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] DNA Methylome Analysis Identifies Transcription Factor-Based Epigenomic Signatures of Multilineage Competence in Neural Stem/Progenitor Cells.2017

    • Author(s)
      Sanosaka T, Imamura T, Hamazaki N, Chai M, Igarashi K, Ideta-Otsuka M, Miura F, Ito T, Fujii N, Ikeo K, Nakashima K
    • Journal Title

      Cell Rep

      Volume: 20 Issue: 12 Pages: 2992-3003

    • DOI

      10.1016/j.celrep.2017.08.086

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] NEUROD1 instructs neuronal conversion in non-reactive astrocytes.2017

    • Author(s)
      Brulet R, Matsuda T, Zhang L, Miranda C, Giacca M, Kaspar BK, Nakashima K, Hsieh J
    • Journal Title

      Stem Cell Reports

      Volume: 8 Issue: 6 Pages: 1506-1515

    • DOI

      10.1016/j.stemcr.2017.04.013

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Emerging mechanisms underlying astrogenesis in the developing mammalian brain2017

    • Author(s)
      Takouda J, Katada S, Nakashima K
    • Journal Title

      Proceedings of the Japan Academy, Series B

      Volume: 93 Issue: 6 Pages: 386-398

    • DOI

      10.2183/pjab.93.024

    • NAID

      130005696812

    • ISSN
      0386-2208, 1349-2896
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Hypoxia epigenetically confers astrocytic differentiation potential on human pluripotent cell-derived neural precursor cells.2017

    • Author(s)
      Yasui T, Uezono N, Nakashima H Noguchi H, Matsuda T, Noda-Andoh T, Okano H, Nakashima K:
    • Journal Title

      Stem Cell Reports

      Volume: 8 Issue: 6 Pages: 1743-1756

    • DOI

      10.1016/j.stemcr.2017.05.001

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Dynamics of the cell division orientation of granule cell precursors during cerebellar development.2017

    • Author(s)
      Miyashita S, Adachi T, Yamashita M, Sota T, Hoshino M:
    • Journal Title

      Mech Dev

      Volume: 147 Pages: 1-7

    • DOI

      10.1016/j.mod.2017.06.002

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pathologic Active mTOR Mutation in Brain Malformation with Intractable Epilepsy Leads to Cell-Autonomous Migration Delay2017

    • Author(s)
      Hanai S, Sukigara S, Dai H, Owa T, Horike SI, Otsuki T, Saito T, Nakagawa E, Ikegaya N, Kaido T, Sato N, Takahashi A, Sugai K, Saito Y, Sasaki M, Hoshino M, Goto YI, Koizumi S, Itoh M
    • Journal Title

      The American Journal of Pathology

      Volume: 187 Issue: 5 Pages: 1177-1185

    • DOI

      10.1016/j.ajpath.2017.01.015

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neuronal Migration and AUTS2 Syndrome2017

    • Author(s)
      Kei Hori、Mikio Hoshino
    • Journal Title

      Brain Sciences

      Volume: 7 Issue: 5 Pages: 54-54

    • DOI

      10.3390/brainsci7050054

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Organizing activity of Fgf8 on the anterior telencephalon.2017

    • Author(s)
      Sato T, Kikkawa T, Saito T, Itoi K, Osumi N
    • Journal Title

      Dev Growth Differ

      Volume: 59 Issue: 9 Pages: 701-712

    • DOI

      10.1111/dgd.12411

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Early postnatal vocalizations predict sociability and spatial memory in C57BL6/J mice: individual differences in behavioral traits emerge early in development.2017

    • Author(s)
      Yoshizaki Kaichi, Koike Kohei, Kimura Ryuichi, Osumi Noriko
    • Journal Title

      PLoS One

      Volume: - Issue: 11 Pages: e0186798-e0186798

    • DOI

      10.1371/journal.pone.0186798

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Direct estimation of de novo mutation rates in a chimpanzee parent-offspring trio by ultra-deep whole genome sequencing2017

    • Author(s)
      Tatsumoto Shoji、Go Yasuhiro、Fukuta Kentaro、Noguchi Hideki、Hayakawa Takashi、Tomonaga Masaki、Hirai Hirohisa、Matsuzawa Tetsuro、Agata Kiyokazu、Fujiyama Asao
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 13561-13561

    • DOI

      10.1038/s41598-017-13919-7

    • NAID

      120006358802

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Network analysis of exploratory behaviors of mice in a spatial learning and memory task.2017

    • Author(s)
      Suzuki Y and Imayoshi I
    • Journal Title

      PLoS One.

      Volume: 12

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Firing rate estimation using infinite mixture models and its application to neural decoding.2017

    • Author(s)
      Shibue R, Komaki F:
    • Journal Title

      Journal of Neurophysiology

      Volume: 118 Issue: 5 Pages: 2902-2913

    • DOI

      10.1152/jn.00818.2016

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Multivariate time series decomposition into oscillation components.2017

    • Author(s)
      Matsuda T, Komaki F:
    • Journal Title

      Neural Computation

      Volume: 29 Issue: 8 Pages: 2055-2075

    • DOI

      10.1162/neco_a_00981

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Electroporation in the Rodent Embryonic Brain Using Whole Embryo Culture System.2017

    • Author(s)
      Kikkawa T, Takahashi M, Osumi N
    • Journal Title

      Curr Protoc Neurosci.

      Volume: 78 Issue: 1 Pages: 1-16

    • DOI

      10.1002/cpns.21

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Manipulation of Promoter-Associated Noncoding RNAs in Mouse Early Embryos for Controlling Sequence-Specific Epigenetic Status.2017

    • Author(s)
      Hamazaki N, Nakashima K, Imamura T.
    • Journal Title

      Methods Mol Biol

      Volume: 1543 Pages: 271-282

    • DOI

      10.1007/978-1-4939-6716-2_16

    • ISBN
      9781493967148, 9781493967162
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A point process modeling approach for investigating the effect of online brain activity on perceptual switching,2017

    • Author(s)
      Matsuda, T., Kitajo, K., Yamaguchi, Y., and Komaki, F.
    • Journal Title

      NeuroImage

      Volume: 152 Pages: 50-59

    • DOI

      10.1016/j.neuroimage.2017.02.068

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Time series decomposition into oscillation components and phase estimation2017

    • Author(s)
      Matsuda, T. and Komaki, F.
    • Journal Title

      Neural Computation

      Volume: 29 Issue: 2 Pages: 332-367

    • DOI

      10.1162/neco_a_00916

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Individual Differences and the Effect of Face Configuration Contexts in the McGurk Effect2017

    • Author(s)
      Ujiie, Y., Asai, Y., Wakabayashi A.
    • Journal Title

      Experimental Brain Research

      Volume: 印刷中

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Paternal Aging Affects Behavior in Pax6 Mutant Mice: A Gene/Environment Interaction in Understanding Neurodevelopmental Disorders.2016

    • Author(s)
      Yoshizaki K, Furuse, T, Kimura R, Tucci V, Kaneda H, Wakana S and Osumi N
    • Journal Title

      PLoS One

      Volume: 11 Issue: 11 Pages: e0166665-e0166665

    • DOI

      10.1371/journal.pone.0166665

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Mechanisms of DHA transport to the brain and potential therapy to neurodegenerative diseases.2016

    • Author(s)
      Lo Van A, Sakayori N, Hachem M, Belkouch M, Picq M, Lagarde M, Osumi N, Bernoud-Hubac N.
    • Journal Title

      Biochimie

      Volume: 130 Pages: 163-167

    • DOI

      10.1016/j.biochi.2016.07.011

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Maternal Nutritional Imbalance between Linoleic Acid and Alpha-Linolenic Acid Increases Offspring’s Anxious Behavior with a Sex-Dependent Manner in Mice2016

    • Author(s)
      Sakayori, N., Tokuda, H., Yoshizaki, K., Kawashima, H., Innis, SM., Shibata, H. and Osumi, N
    • Journal Title

      The Tohoku Journal of Experimental Medicine

      Volume: 240 Issue: 1 Pages: 31-37

    • DOI

      10.1620/tjem.240.31

    • NAID

      130005406204

    • ISSN
      0040-8727, 1349-3329
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Identification of Protein Kinase Substrates by the Kinase-Interacting Substrate Screening (KISS) Approach2016

    • Author(s)
      Amano, M., Nishioka, T., Yura, Y., and Kaibuchi, K.
    • Journal Title

      Curr Protoc Cell Biol

      Volume: 72 Issue: 1 Pages: 14161-141612

    • DOI

      10.1002/cpcb.8

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Brain enhancer activities at the gene-poor 5p14.1 utism-assocaited locus.2016

    • Author(s)
      Inoue YU, Inoue T
    • Journal Title

      Sci Rep.

      Volume: 9 Issue: 1 Pages: 31227-31227

    • DOI

      10.1038/srep31227

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prenatal deletion of DNA methyltransferase 1 in neural stem cells impairs neurogenesis and causes anxiety-like behavior in adulthood.2016

    • Author(s)
      Noguchi H, Kimura A, Murao N, Namihira M. Nakashima K.
    • Journal Title

      Neurogenesis (Austin)

      Volume: 3 Issue: 1 Pages: e1232679-e1232679

    • DOI

      10.1080/23262133.2016.1232679

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Single-neuron and genetic correlates of autistic behavior in macaque2016

    • Author(s)
      K. Yoshida, Y. Go, I. Kushima, A. Toyoda, A. Fujiyama, H. Imai, N. Saito, A. Iriki, N. Ozaki, M. Isoda
    • Journal Title

      Science Advances

      Volume: 2 Issue: 9

    • DOI

      10.1126/sciadv.1600558

    • NAID

      120006222007

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] Regulatory mechanism of neural stem cells revealed by optical manipulation of gene expressions2021

    • Author(s)
      今吉 格
    • Organizer
      第11回新潟大学脳研究所共同研究拠点国際シンポジウム
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Transgenerational Epigenetics: A Key to Understand Neurodevelopmental Diseases2021

    • Author(s)
      大隅 典子
    • Organizer
      CINP2021 VIRTUAL WORLD CONGRESS
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ミクログリアからニューロンへの直接分化転換による脳梗塞治療法の開発2021

    • Author(s)
      中島欽一
    • Organizer
      STROKE2021
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Multiple Monkey Pose Estimation Using OpenPose2021

    • Author(s)
      Blanco, N.S., Labuguen,R., Matsumoto, J., Go,Y., Inoue, K.,Shibata, T.
    • Organizer
      International workshop (VAIB) in an international conference (ICPR)
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Optical membrane potential recordings with voltage-sensitive dye (VSD) enabling recordings of rare and unique neuronal activity patterns2020

    • Author(s)
      Y Tominaga, R Kajiwara, T Tominaga
    • Organizer
      Society for Neuroscience, Global Connectome (Online)
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] VSDイメージングによる神経回路毒性の網羅的評価2020

    • Author(s)
      冨永 貴志, 冨永 洋子
    • Organizer
      第47回日本毒性学会学術年会 (仙台、オンライン)
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 単回頻回の膜電位感受性色素( VSD)による広視野可視化法 は神経回路の特異な活動や振動現象の発見に役立つ2020

    • Author(s)
      冨永 貴志、梶原 利一、冨永 洋子
    • Organizer
      第43回日本神経科学大会(神戸、オンライン)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 発達期および成体期におけるマウス嗅皮質神経回路の膜電位イメージング解析2020

    • Author(s)
      待田 燿子 , 山田 悠太 , 冨永 貴志 , 梶原 利一
    • Organizer
      第43回日本神経科学大会(神戸、オンライン)
    • Related Report
      2020 Annual Research Report
  • [Presentation] Imaging analysis of the long-term potentiation of the mouse hippocampal activityマウス海馬の長期増強を膜電位感受色素によるイメージングで観察する2020

    • Author(s)
      冨永 洋子, 竹歳 麻紀子, 冨永 貴志
    • Organizer
      第58回日本生物物理学会(群馬、オンライン)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 発生発達期暴露による嗅球神経新生影響~毒性評価としての嗅球利用を探る~2020

    • Author(s)
      今吉 格
    • Organizer
      第47回日本毒性学会学術年会
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Toward understanding and manipulation of neural bases underlying animal behaviors and psychiatric diseases2020

    • Author(s)
      今吉 格
    • Organizer
      第43回日本分子生物学会年会シンポジウム
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 個性を科学するためのチャレンジ2020

    • Author(s)
      大隅 典子
    • Organizer
      NTTニケーション科学基礎研究所オープンハウス
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 先天異常からDOHaDへ:鍵となる次世代継承エピジェネティ クス2020

    • Author(s)
      大隅 典子
    • Organizer
      先天異常学会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 精神医学研究に対する齧歯類を用いた基礎研究の貢献2020

    • Author(s)
      大隅 典子
    • Organizer
      日本精神神経学会総会シンポジウム
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Transgenerational epigenetics: a possible scenario for the onset of neurodevelopmental diseases2020

    • Author(s)
      大隅 典子
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] レット症候群原因因子MeCP2のマイクロRNAを介した神経幹細胞分化制御機構の解明2020

    • Author(s)
      中島欽一
    • Organizer
      第47回日本毒性学会学術年会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 小脳顆粒細胞におけるMeis1の新規機能による分化制御機構の解明2020

    • Author(s)
      大輪智雄、田谷真一郎、宮下聡、西岡朋生、中村卓郎、五飯塚僚、貝淵弘三、星野幹雄
    • Organizer
      第43回日本分子生物学会年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 精神疾患関連遺伝子AUTS2の神経発生における機能と病理2020

    • Author(s)
      Hoshino M(シンポジウムオーガナイザー), Hori K
    • Organizer
      NPBPPP
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 小脳顆粒細胞分化の分子機構と発達期曝露による影響評価2020

    • Author(s)
      Hoshino M, Miyashita S
    • Organizer
      日本毒性学会年会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Neuronal progenitors and synapses in psychiatric disease mouse model2020

    • Author(s)
      Hoshino M, Hori K
    • Organizer
      日本神経科学会大会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] DSCAM Regulates Neuronal Delamination Through Suppression of RapGEF2/Rap1 and N-Cadherin2020

    • Author(s)
      Arimura N, Okada M, Taya S, Dewa K, Uetake H, Miyashita S, Nishioka T, Inoue YU, Inoue T, Kaibuchi K, Hoshino M
    • Organizer
      Adult Neurogenesis Meeting
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Analysis of Autism Susceptibility Candidate 2 (AUTS2) gene during development2018

    • Author(s)
      Hoshino M, Hori K
    • Organizer
      第8回 新潟大学脳研究所共同研究拠点国際シンポジウム
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] The role of AUTS2 in synaptic formation and the cognitive brain functions2018

    • Author(s)
      Hori K, Nagai T, Shan W, Yamada M, Shiraishi R, Sakamoto A, Kanno K, Abe M, Yamada K, Sakimura K, Hoshino M
    • Organizer
      第8回新潟大学脳研究所共同研究拠点国際シンポジウム
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Visualization and humanization of oxytocin receptor expressions in mice; towards the clinical application of oxytocin to autism spectrum disorders2018

    • Author(s)
      Inoue YU, Morimoto Y, Inoue T
    • Organizer
      第9回 武田科学振興財団薬科学シンポジウム Genome Editing Towards Medicinal Applications
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Paternal aging-induced differential DNA methylation in sperm: possible effects on gene expression and behavior in offspring2018

    • Author(s)
      Osumi N
    • Organizer
      第123回日本解剖学会総会・全国学術集会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 遺伝子発現の光制御システムを用いた神経幹細胞・ニューロン新生の制御機構の解析2018

    • Author(s)
      今吉 格
    • Organizer
      第一回 三融会・武田神経科学シンポジウム
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 霊長類における精神・神経疾患関連遺伝子解析と認知ゲノミクスの展望2018

    • Author(s)
      郷康広
    • Organizer
      平成29年度京都大学霊長類研究所共同利用研究会「霊長類における認知ゲノム研究」
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 自閉症モデルマーモセット脳における時空間遺伝子発現解析2018

    • Author(s)
      郷康広,佐々木哲也,中垣慶子,小賀智文,辰本将司,石川裕恵,臼井千夏,一戸紀孝
    • Organizer
      第7回日本マーモセット研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 遺伝子発現動態の光操作から明らかになる神経幹細胞の制御機構2017

    • Author(s)
      今吉 格
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      浜松(アクトシティ浜松)
    • Year and Date
      2017-03-29
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 父加齢が次世代の行動に影響を与えるエピジェネティックなメカニズム:新たな自閉スペクトラム症の提案2017

    • Author(s)
      吉崎 嘉一、小池 佐、木村 龍一、吉川 貴子、沖 真弥、稲田 仁、松居 靖之、河野 友宏、大隅典子
    • Organizer
      第122回日本解剖学会総会・全国学術集会
    • Place of Presentation
      長崎(長崎大学坂本キャンパス)
    • Year and Date
      2017-03-28
    • Related Report
      2016 Annual Research Report
  • [Presentation] 個性の生まれる源に関する生物学的考察2017

    • Author(s)
      大隅典子
    • Organizer
      JST CREST「認知ミラーリング」キックオフシンポジウム
    • Place of Presentation
      東京(東京大学先端科学技術研究センター)
    • Year and Date
      2017-03-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] 霊長類における精神・神経疾患関連遺伝子解析と認知ゲノミクスの展望2017

    • Author(s)
      郷康広
    • Organizer
      京都大学霊長類研究所共同利用研究会
    • Place of Presentation
      犬山(京都大学霊長類研究所)
    • Year and Date
      2017-03-18
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 父加齢による次世代個体の行動への影響:エピジェネティックな背景と神経発達障害モデルの可能性2017

    • Author(s)
      大隅典子
    • Organizer
      第90回日本薬理学会
    • Place of Presentation
      長崎(長崎ブリックホール・長崎新聞文化ホール)
    • Year and Date
      2017-03-17
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] ゲノムを通して我が身を知る ヒトとサルの間にあるもの2017

    • Author(s)
      郷康広
    • Organizer
      国立精神・神経医療研究セミナー
    • Place of Presentation
      小平(国立精神・神経医療研究センター)
    • Year and Date
      2017-02-24
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Insights into Rett Syndrome using Neural Stem Cells2017

    • Author(s)
      Nakashima K.
    • Organizer
      Keystone Symposium
    • Place of Presentation
      Olympic Valley, USA
    • Year and Date
      2017-01-08
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 個性が象る脳梁・時間が育む脳梁2017

    • Author(s)
      續木大介、多賀厳太郎、渡辺はま、保前文高
    • Organizer
      次世代脳プロジェクト冬のシンポジウム2017
    • Related Report
      2017 Annual Research Report
  • [Presentation] 絵画呼称時の発話に至る時系列に関する検討2017

    • Author(s)
      Eunbi P、保前文高
    • Organizer
      次世代脳プロジェクト冬のシンポジウム2017
    • Related Report
      2017 Annual Research Report
  • [Presentation] 乳児がもつ個人性の探求2017

    • Author(s)
      保前文高
    • Organizer
      次世代脳プロジェクト冬のシンポジウム2017
    • Related Report
      2017 Annual Research Report
  • [Presentation] 脳の形態形成に現れる乳幼児の個性2017

    • Author(s)
      保前文高
    • Organizer
      日本社会心理学会第58回大会シンポジウム
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 新生児・乳児を対象としたfNIRS計測2017

    • Author(s)
      渡辺はま
    • Organizer
      日本心理学会第81回大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] General principle and individual difference in dynamics of early development of human brain and behavior(脳と行動の初期発達のダイナミクスにおける一般法則と個性)2017

    • Author(s)
      Taga G, Watanabe H, Homae F
    • Organizer
      第27回 日本神経回路学会全国大会(JNNS2017)
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 発達脳における機能的クラスタリング2017

    • Author(s)
      保前文高、渡辺はま、多賀厳太郎
    • Organizer
      第20回日本光脳機能イメージング学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 発達期における脳と言語-普遍性と固有性の共存2017

    • Author(s)
      保前文高
    • Organizer
      日本言語学会第154回大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 他者の痛み観察時の不快感における道具と身体の接触の影響2017

    • Author(s)
      河村康佑、若林明雄
    • Organizer
      日本基礎心理学会第36回大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 刺激の弁別しやすさが視覚的注意シフト方向の異方性に与える影響.2017

    • Author(s)
      永登大和、若林明雄
    • Organizer
      日本基礎心理学会第36回大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Pre-existing reduced functional connectivity between cognitive control network and salience network enhances PTSD symptoms after a disaster: evidence from a longitudinal2017

    • Author(s)
      Sekiguchi A, Kotozaki Y, Sugiura M, Nakagawa S, Nouchi R, Miyauchi CM, Takeuchi H, Taki Y, Kawashima R
    • Organizer
      Society for Neuroscience 2017(USA)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Uniqueness of the gaze cue in spatial anisotropy of visual attention.2017

    • Author(s)
      Eito H, Wakabayashi A
    • Organizer
      Fechner Day 2017 The 33rd Annual meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Gray matter structures associated with loneliness in young adults2017

    • Author(s)
      Nakagawa S, Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Kotozaki Y, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Kunitoki K, Sassa Y, Kawashima R
    • Organizer
      第1回ヒト脳イメージング研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 酸素濃度によるヒト神経幹細胞分化のエピジェネティック制御2017

    • Author(s)
      中島 欽一
    • Organizer
      日本薬学会第138年会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 胎生期エピジェネティック撹乱による遅発性学習記憶障害とてんかん感受性増加のメカニズム2017

    • Author(s)
      中島 欽一
    • Organizer
      第26回海馬と高次脳機能学会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] DNA methylomes identifiy transcription factor-based epigenomic signatures for timed acquisition of differentiation competence in neural stem/progenitor cells towards neuronal and glia lineages2017

    • Author(s)
      今村拓也、佐野坂司、浜崎伸彦、Chai Muh Chyi、五十嵐勝秀、大塚まき、三浦史仁、伊藤隆司、藤井信之、池尾一穂、中島欽一
    • Organizer
      4th World Congress of Reproductive Biology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Hypoxia epigenetically confers astrocytic differentiation potential on human pluripotent cell-derived neural precursor cells2017

    • Author(s)
      中島 欽一
    • Organizer
      The 72nd Fujihara Seminar Molecular Mechanism of Molding and Disruption of the Epigenomes Underlying Cellular Community
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Regulation of non-coding RNA contributes to the complete cessation of cell proliferation of neuron-like cells2017

    • Author(s)
      今村拓也、山本直樹、阿形清和、中島欽一
    • Organizer
      第43回内藤コンファレンス
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] DNA Methylation Regulting Neuron-Glia Fate Switching of Neural Stem Cells2017

    • Author(s)
      中島 欽一
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] エピゲノム変換を介したミクログリアからニューロンへの直接分化転換機構の解明2017

    • Author(s)
      松田泰斗、入江剛史、アデフィンアリア、中島欽一
    • Organizer
      第11回日本エピジェネティクス研究会年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] The functional analysis of a down syndrome-associated gene in neuronal migration of midbrain neurons2017

    • Author(s)
      Arimura N, Dewa K, Okada M, Yanagawa Y, Taya S, Hoshino M
    • Organizer
      第40回日本分子生物学会年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 生後発達期大脳における自閉症感受性遺伝子AUTS2の生理機能の解析2017

    • Author(s)
      堀啓,永井拓,Wei Shan,山田光代,白石玲花,菅野康太,坂本亜沙美,阿部学,崎村健司,山田清文,星野幹雄
    • Organizer
      第40回日本分子生物学会年会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 各種精神疾患に関連するAUTS2遺伝子2017

    • Author(s)
      星野幹雄
    • Organizer
      第11回 In vivo実験医学シンポジウム:精神神経疾患における病態解明と治療への応用
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Neurogenesis: Specification of Cerebellar Progenitors2017

    • Author(s)
      Hoshino M
    • Organizer
      the 8th International Symposium of The Society for Research on the Cerebellum and Ataxia (Canada)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Generation of Pax6-IRES-EGFP knock-in mouse via cloning-free CRISPR/Cas9 system for neurodevelopmental researches2017

    • Author(s)
      Inoue YU, Hoshino M, Inoue T
    • Organizer
      Society for Neuroscience2017(USA)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] KANPHOS (Kinase-Associated Phospho-Signaling) Platform2017

    • Author(s)
      天野睦紀、西岡朋生、黒田啓介、吉本潤一郎、観音隆幸、臼井支朗、貝淵弘三
    • Organizer
      第69回日本細胞生物学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] リン酸化プロテオミクスによるニューロモジュレーターシグナルの解明2017

    • Author(s)
      天野睦紀
    • Organizer
      第39回神経組織培養研究会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Paternal aging-induced differential DNA methylation in sperm: possible effects on gene expression and behavior in offspring2017

    • Author(s)
      Osumi N, Kimura R, Yoshizaki K, Koike T, Oki S, Mochizuki K, Kikkawa T, Inada H, Matsui Y, Kono T
    • Organizer
      Society for Neuroscience2017(USA)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 多様な<個性>を創発する分子・神経・社会基盤の統合的理解を目指して-複合領域研究の推進2017

    • Author(s)
      大隅典子
    • Organizer
      日本社会心理学会第58回大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Paternal aging model of autism: a possible epigenetic mechanism2017

    • Author(s)
      Osumi N
    • Organizer
      Albert Einstein College of Medicine 廣井研究室セミナー(USA)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Trans-generational transmission of ASD-like phenotypes possibly via sperm epigenetic alteration caused by paternal age2017

    • Author(s)
      Kimura R, Yoshizaki K, Koike T, Oki S, Aoki N, Mochizuki K, Kobayashi H, Kikkawa T, Inada H, Matsui Y, Kono T, Osumi N
    • Organizer
      国際自閉症カンファレンス東京2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 父加齢の次世代マウス行動への影響に関わるエピゲノム機構2017

    • Author(s)
      大隅典子
    • Organizer
      第47回 日本神経精神薬理学会 合同年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Towards Elucidation of Generative Brain Systems for Individuality2017

    • Author(s)
      Osumi N
    • Organizer
      第27回日本神経回路学会全国大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 脳の発生発達と神経新生における脂質栄養:心のレジリエンスのために2017

    • Author(s)
      大隅典子
    • Organizer
      日本脂質栄養学会第26回大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Effect of paternal aging on behavior of offspring in animal models of neurodevelopmental diseases2017

    • Author(s)
      Osumi N
    • Organizer
      第60回日本神経化学会大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Paternal aging affects offspring's behavior possibly via an epigenetic mechanism involving a transcriptional repressor REST2017

    • Author(s)
      Osumi N
    • Organizer
      Link_ping University-JSPS Meeting(Sweden)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 齧歯類を用いた音声コミュニケーション解析と遺伝的・環境的影響2017

    • Author(s)
      大隅典子
    • Organizer
      日本言語学会第154回大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 「個性」を科学する:脳・神経系の多様性から「個性」創発の理解へ2017

    • Author(s)
      大隅典子
    • Organizer
      第116回日本皮膚科学会総会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Regulatory mechanism of neural stem cells revealed by optical manipulation of gene expressions2017

    • Author(s)
      今吉 格
    • Organizer
      ConBio2017シンポジウム (3AS09)神経科学研究技術の最前線
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Regulatory Mechanism of Neural Stem Cells Revealed by Optical Manipulation of Gene Expressions2017

    • Author(s)
      今吉 格
    • Organizer
      第24回 日本時間生物学会学術大会シンポジウム
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 遺伝子発現の光操作と神経幹細胞研究への応用2017

    • Author(s)
      今吉 格
    • Organizer
      細胞を創る研究会10.0 シンポジウム
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Functional significance of neurogenesis in the postnatal and adult brain2017

    • Author(s)
      今吉 格
    • Organizer
      第40回日本神経科学大会 シンポジウム
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Neurogenesis in the postnatal and adult brain2017

    • Author(s)
      今吉 格
    • Organizer
      第40回日本神経科学大会 ジョセフ・アルトマン記念発達神経科学賞受賞記念講演
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Regulatory Mechanism of Neural Stem Cells Revealed by Optical Manipulation of Gene Expressions2017

    • Author(s)
      今吉 格
    • Organizer
      第12回上原国際シンポジウム「Meke Life Visible」シンポジウム
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 霊長類脳における比較トランスクリプトーム・エピゲノム解析2017

    • Author(s)
      郷康広,辰本将司,Xu C,Li Q,Efimova O,Liu H,大石高生,鵜殿俊史,山口勝司,重信秀治,柿田明美,那波宏之,Khaitovich P
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Related Report
      2017 Annual Research Report
  • [Presentation] ゲノムを通して我が身を知る~ヒト集団にみられる「個性」創発の起源に関する論考~2017

    • Author(s)
      郷康広
    • Organizer
      日本社会心理学会第58回大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Spatiotemporal brain transcriptome architecture and application for disease model in marmosets2017

    • Author(s)
      郷康広
    • Organizer
      第27回日本神経回路学会全国大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Spatiotemporal brain transcriptome architecture and application for disease model in marmosets2017

    • Author(s)
      Go Y
    • Organizer
      第60回日本神経化学学会大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] ロングリード型NGSを用いたニホンザル新規ゲノム配列決定2017

    • Author(s)
      郷康広,辰本将司,石川裕恵
    • Organizer
      日本進化学会第19回大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ロングリード型NGSを用いたニホンザル新規ゲノム配列決定2017

    • Author(s)
      郷康広,辰本将司,石川裕恵
    • Organizer
      NGS現場の会第五回研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ゲノムを通して我が身を知る~人とヒトとサルの間にあるもの~2017

    • Author(s)
      郷康広
    • Organizer
      愛知高等学校特別講演会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Voltage-sensitive dye imaging study of the input-dependent GABAergic control of the paired burst facilitation (PBF) in area CA1 of the hippocampus2017

    • Author(s)
      Tominaga T and Tominaga Y
    • Organizer
      Society for Neuroscience2017(USA)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Voltage-sesitive dye signal analysis of inhibitory components in mouse perirhinal-entorrhinal cortical slices2017

    • Author(s)
      Wakayama Y, Kamada S, Yamada Y, Tominaga T, Kajiwara R
    • Organizer
      Society for Neuroscience2017(USA)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 「イントロダクション」ワークショップ「個性」創発神経基盤の統合的理解に向けた階層横断的解析2017

    • Author(s)
      冨永貴志
    • Organizer
      生命科学系合同年次大会 ConBio2017
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 膜電位イメージングの技術支援:実施例から2017

    • Author(s)
      冨永貴志
    • Organizer
      新学術領域「個性」創発脳の第2回若手の会・技術講習会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 海馬CA1野のペアドバーストファシリテーション(PBF)のGABAergicなフィードフォワード,フィードバック調節:膜電位感受性色素による研究2017

    • Author(s)
      冨永貴志,冨永洋子
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] カフェイン投与により誘発されるラット視覚野オシレーションにおけるnon-NMDA受容体とNMDA受容体の相互交錯的関与2017

    • Author(s)
      吉村 弘,須貝 外喜夫,加藤 伸郎,冨永 貴志,冨永 洋子,長谷川 敬展,姚 陳娟,赤松 徹也
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 膜電位イメージングによる嗅周囲皮質の抑制性/興奮性神経活動の層分布解析2017

    • Author(s)
      和歌山 ゆうか,鎌田 翔仁,山田 悠太,冨永 貴志,梶原 利一
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 神経興奮伝播の促進に関与するマウス嗅皮質神経回路可塑性の膜電位イメージング2017

    • Author(s)
      梶原 利一,和歌山 ゆうか,冨永 洋子,冨永 貴志
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 情動認知行動影響の毒性評価における神経回路機能イメージング法を用いた神経基盤解析2017

    • Author(s)
      冨永貴志,冨永洋子
    • Organizer
      第44回日本毒性学会学術年会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] ゾウリムシと電気生理学2017

    • Author(s)
      冨永貴志
    • Organizer
      日本動物学会第88回大会 シンポジウム「ゾウリムシ研究の新潮流」
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Information Geometry of predictive densities and its application to Poisson regression2017

    • Author(s)
      Komaki F
    • Organizer
      Lilac International Conference of Application on Statistics (LICAS 2017)(China)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Shrinkage Priors for Poisson-Based Models and Their Applications2017

    • Author(s)
      Komaki F
    • Organizer
      Joint Statistical Meetings 2017(JSM2017)(USA)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neural decoding based on an infinite mixture model2017

    • Author(s)
      Shibue R and Komaki F
    • Organizer
      The 1st International Conference on Econometrics and Statistics (EcoSta 2017)(HongKong)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A predictive approach to statistical problems with multiplicity2017

    • Author(s)
      Komaki F
    • Organizer
      CMStatistics 2017(UK)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] The muscarinic acetylcholine receptor subtype involved in the suppression of the epileptic discharges with the carbachol-induced beta oscillation in rat hippocampal slices2017

    • Author(s)
      T Sawada, Natsume K
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] The hippocampal beta rhythm and the computational model of it2017

    • Author(s)
      Kageyama I, Natsume K
    • Organizer
      NOLTA2017 Special Sessions
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Missing value estimation of sEMG signals using BGPLVM toward control of a multi-fingered prosthetic hand2017

    • Author(s)
      Dwivedi SK, Koganti N, Shibata T
    • Organizer
      第27回日本神経回路学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] A Study on Automatic OWAS Classification of the Working Postures of a Caregiver2017

    • Author(s)
      Omure Y, Izumi H, Shibata T
    • Organizer
      39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society(Korea)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A Novel Practical Approach to Prosthetic Control of Continuous Multi-Fingered Kinematics with a Low-Cost Wearable sEMG Device2017

    • Author(s)
      Shibata T, Shibata T
    • Organizer
      39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society(Korea)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The muscarinic acetylcholine receptor subtype involved in the suppression of the epileptic discharges with the carbachol-induced beta oscillation in rat hippocampal slices2017

    • Author(s)
      T Sawada, Natsume K
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] The hippocampal beta rhythm and the computational model of it2017

    • Author(s)
      Kageyama I, Natsume K
    • Organizer
      NOLTA2017 Special Sessions(Mexico)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 表現型データ統合データベースJ-Phenomeにおける計測メタデータの整理統合2017

    • Author(s)
      桝屋啓志
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] RDF-based integration of phenotype data of experimental animals in Japan2017

    • Author(s)
      Masuya H
    • Organizer
      NIX-odML Global Workshop & Hackathon 2017
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 海馬生後ニューロン新生の破綻と発達障害との関係について2016

    • Author(s)
      今吉 格
    • Organizer
      発達障害研究所公開セミナー 2016
    • Place of Presentation
      春日井(愛知県心身障害者コロニー)
    • Year and Date
      2016-12-22
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Spatiotemporal brain transcriptome architecture in the common marmoset2016

    • Author(s)
      Go, Y.
    • Organizer
      The 6th annual conference of Japan Society for Marmoset Research, Brain/MINDS international symposium.
    • Place of Presentation
      東京(東京大学弥生講堂)
    • Year and Date
      2016-12-14
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 霊長類脳の構造・機能をささえる分子基盤解明にむけたマーモセット全脳遺伝子発現動態2016

    • Author(s)
      郷康広
    • Organizer
      革新的技術による脳機能ネットワークの全容解明プロジェクト・臨床研究グループ分科会
    • Place of Presentation
      東京(東京大学付属病院)
    • Year and Date
      2016-12-11
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Shrinkage priors for a class of Poisson regression models Computational and Methodological Statistics2016

    • Author(s)
      Komaki, F
    • Organizer
      CMStatistics 2016
    • Place of Presentation
      Seville, Spain
    • Year and Date
      2016-12-10
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] クローニングフリーCRISPR/Casシステムによるノックインマウス作製2016

    • Author(s)
      井上-上野由紀子,井上高良
    • Organizer
      第39回日本分子生物学会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2016-12-02
    • Related Report
      2016 Annual Research Report
  • [Presentation] CRISPR/Cas9システムを用いた複数クラシックカドヘリン遺伝子ノックアウトマウスの作出2016

    • Author(s)
      平賀孔,井上-上野由紀子,星野幹雄,井上高良
    • Organizer
      第39回日本分子生物学会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2016-12-02
    • Related Report
      2016 Annual Research Report
  • [Presentation] 中脳神経細胞の細胞移動におけるダウン症関連因子の機能解析2016

    • Author(s)
      有村奈利子,出羽健一,岡田茉子,柳川右千夫,田谷真一郎,星野幹雄
    • Organizer
      第39回日本分子生物学会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2016-12-01
    • Related Report
      2016 Annual Research Report
  • [Presentation] 小脳顆粒細胞における分裂面と娘細胞の運命決定メカニズムの解析2016

    • Author(s)
      足立透真,宮下聡,井上貴文,星野幹雄:
    • Organizer
      第39回日本分子生物学会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2016-12-01
    • Related Report
      2016 Annual Research Report
  • [Presentation] 父加齢による精子のDNAメチル化変化は仔の行動や遺伝子発現に影響する2016

    • Author(s)
      木村龍一, 吉崎嘉一, 小池佐, 小池航平, 吉川貴子, 稲田仁, 松居靖久, 河野友宏 、大隅典子
    • Organizer
      第39回分子生物学会年会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2016-11-30
    • Related Report
      2016 Annual Research Report
  • [Presentation] Meis1の小脳顆粒細胞における多段階発生制御2016

    • Author(s)
      大輪智雄,田谷真一郎,宮下聡,西岡朋生,中村卓郎,五飯塚僚,貝淵弘三,星野幹雄
    • Organizer
      第39回日本分子生物学会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2016-11-30
    • Related Report
      2016 Annual Research Report
  • [Presentation] 「使える」膜電位感受性色素による神経回路解析法 “Conventional”voltage sensitive dye imaging of neural circuit activity 公募シンポジウム「神経活動イメージングの最先端:新規ツールとその活用2016

    • Author(s)
      冨永 貴志, 冨永 洋子
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば(つくば国際会議場)
    • Year and Date
      2016-11-25
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Female preference for male’s vocalizations in C57BL6/J mice2016

    • Author(s)
      Matsumoto Y, Asaba A, Kanno K, Kikusui T, Okanoya K
    • Organizer
      日本動物心理学会第76回大会
    • Place of Presentation
      札幌(北海道大学)
    • Year and Date
      2016-11-24
    • Related Report
      2016 Annual Research Report
  • [Presentation] Activation of GABAA-receptors by high-frequency stimuli causes paired burst facilitations in area CA1 of the hippocampal slice2016

    • Author(s)
      Tominaga T and Tominaga Y.
    • Organizer
      Neuroscience 2016
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-15
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Role of Meis1 in the cerebellar development.2016

    • Author(s)
      Owa T, Taya S, Miyashita S, Nishioka T, Kaibuchi K, Hoshino M
    • Organizer
      Neuroscience2016
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-14
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Network plasticity facilitating the neural excitation propagation between the perirhinal and entorhinal cortices as revealed by voltage-sensitive dye imaging2016

    • Author(s)
      Kajiwara R, Wakayama Y, Tominaga Y, Tominaga T
    • Organizer
      Neuroscience 2016
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-14
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Paternal aging-induced differential DNA methylation in sperm: possible transgenerational effects on gene expression and behavior in offspring2016

    • Author(s)
      Kimura R., Yoshizaki K., Koike T., Koike K., Kikkawa T., Inada H., Matsui Y., Kono T. and Osumi N.
    • Organizer
      Neuroscience 2016
    • Place of Presentation
      San Diego,USA
    • Year and Date
      2016-11-13
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 社会的場面におけるマウスの発声型とその機能2016

    • Author(s)
      松本結,浅場明莉,菅野康太,菊水健史,本田学,岡ノ谷一夫
    • Organizer
      日本動物行動学会大35回大会
    • Place of Presentation
      新潟(新潟大学五十嵐キャンパス)
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
  • [Presentation] 生物学的シティズンシップとリスクコミュニケーション2016

    • Author(s)
      原塑
    • Organizer
      科学技術社会論学会第15回年次研究大会
    • Place of Presentation
      札幌(北海道大学)
    • Year and Date
      2016-11-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] The characteristics of the cortical functional networks in individual infants2016

    • Author(s)
      Homae, F., Watanabe, H., & Taga, G.
    • Organizer
      The Society for Functional Near Infrared Spectroscopy 2016 Biennial Meeting
    • Place of Presentation
      Paris, France
    • Year and Date
      2016-10-16
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Spatiotemporal gene expression trajectory in the human and non-human ape brains2016

    • Author(s)
      Go, Y.
    • Organizer
      The 6th Joint CIN-NIPS International Symposium
    • Place of Presentation
      Tubingen, Germany
    • Year and Date
      2016-10-11
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Paternal aging-induced differential DNA methylation in sperm: possible transgenerational effects on gene expression and behavior.2016

    • Author(s)
      Osumi N.
    • Organizer
      Genome Imprinting Epigenetics and Physiologizal Functions
    • Place of Presentation
      Erice, Italy
    • Year and Date
      2016-10-06
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Paternal aging affects offspring’s behavior: its significance and possible underlying transgenerational epigenetics.2016

    • Author(s)
      Osumi N.
    • Organizer
      The 19th KSBNS Annual Meeting
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2016-09-28
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Individual differences in cognitive styles affected from prenatal hormonal condition2016

    • Author(s)
      Wakabayashi, A.
    • Organizer
      Biocog Research Trends
    • Place of Presentation
      Leipzig, Germany
    • Year and Date
      2016-09-13
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 小脳興奮制シナプス形成におけるダウン症関連分子の機能解析2016

    • Author(s)
      出羽健一,有村奈利子,田谷真一郎,小泉修一,星野幹雄
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡(福岡国際会議場)
    • Year and Date
      2016-09-09
    • Related Report
      2016 Annual Research Report
  • [Presentation] 小脳発生における自閉症感受性遺伝子Auts2の機能解析2016

    • Author(s)
      山城邦比古,青木瞭,坂本亜沙美,堀啓,星野幹雄:
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡(福岡国際会議場)
    • Year and Date
      2016-09-09
    • Related Report
      2016 Annual Research Report
  • [Presentation] Meis1による顆粒細胞の増殖・分化の制御機構の解明2016

    • Author(s)
      大輪智雄,田谷真一郎,宮下聡,西岡朋生,中村卓郎,五飯塚僚,貝淵弘三,星野幹雄
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡(福岡国際会議場)
    • Year and Date
      2016-09-08
    • Related Report
      2016 Annual Research Report
  • [Book] 当事者研究 等身大の<わたしの>発見と回復2020

    • Author(s)
      熊谷 晋一郎
    • Total Pages
      280
    • Publisher
      岩波書店
    • Related Report
      2020 Annual Research Report
  • [Book] 望星2020

    • Author(s)
      大隅 典子
    • Total Pages
      120
    • Publisher
      東海教育研究所
    • Related Report
      2020 Annual Research Report
  • [Book] 3.4章「動物遺伝子の発現」動物の事典2020

    • Author(s)
      井上高良, 星野幹雄
    • Total Pages
      7
    • Publisher
      朝倉書店
    • ISBN
      9784254171662
    • Related Report
      2020 Annual Research Report
  • [Book] 3.5章「遺伝子の発現調節」2020

    • Author(s)
      井上高良, 星野幹雄
    • Total Pages
      9
    • Publisher
      朝倉書店
    • ISBN
      9784254171662
    • Related Report
      2020 Annual Research Report
  • [Book] チンパンジー親子トリオのゲノム解析2018

    • Author(s)
      郷康弘、藤山秋佐夫、阿形清和、松沢哲郎
    • Total Pages
      2
    • Publisher
      科学(岩波書店)
    • Related Report
      2017 Annual Research Report
  • [Book] 脳の誕生2017

    • Author(s)
      大隅 典子
    • Total Pages
      272
    • Publisher
      筑摩書房
    • ISBN
      4480071016
    • Related Report
      2017 Annual Research Report
  • [Book] 「特集=研究公正とRRI」、科学技術社会論学会編集委員会編『研究公正とRRI・科学技術社会論研究第14号』2017

    • Author(s)
      原塑・山内保典(編)
    • Total Pages
      185
    • Publisher
      玉川大学出版部
    • Related Report
      2017 Annual Research Report
  • [Book] 「欧州科学財団、欧州科学アカデミー連合「公正な研究のための欧州行動規範」、科学技術社会論学会編『研究公正とRRI・科学技術社会論研究第14号』2017

    • Author(s)
      原塑(翻訳)
    • Total Pages
      17
    • Publisher
      玉川大学出版部
    • Related Report
      2017 Annual Research Report
  • [Book] 「研究公正とRRI:特集にあたって―科学的合理性の再考」、科学技術社会論学会編『研究公正とRRI・科学技術社会論研究第14号』2017

    • Author(s)
      原塑・山内保典
    • Total Pages
      4
    • Publisher
      玉川大学出版部
    • Related Report
      2017 Annual Research Report
  • [Book] 脳の形成と自閉スペクトラム症、テルモ生命科学芸術財団「生命科学DOKIDOKI研究室」(監修)いのちの不思議を考えよう3  脳の神秘を探ってみよう 生命科学者21人の特別授業症2017

    • Author(s)
      大隅典子
    • Total Pages
      12
    • Publisher
      朝日新聞出版
    • Related Report
      2016 Annual Research Report
  • [Remarks] 「個性」創発脳

    • URL

      http://www.koseisouhatsu.jp/

    • Related Report
      2020 Annual Research Report
  • [Remarks] ニュースレターVol.8

    • URL

      http://www.koseisouhatsu.jp/activity/release/20200918_newsletter_vol8/images/newsletter_vol8.pdf

    • Related Report
      2020 Annual Research Report
  • [Remarks] ニュースレターVol.9

    • URL

      http://www.koseisouhatsu.jp/activity/release/20210318_newsletter_vol9/images/newsletter_vol9.pdf

    • Related Report
      2020 Annual Research Report
  • [Remarks] 多様な「個性」を創発する脳システムの統合的理解(領域略称「個性」創発脳)

    • URL

      http://www.koseisouhatu.jp

    • Related Report
      2018 Annual Research Report
  • [Remarks] 多様な「個性」を創発する脳システムの統合的理解 【領域略称「個性」創発脳】

    • URL

      http://www.koseisouhatsu.jp

    • Related Report
      2017 Annual Research Report
  • [Remarks] 平成28年度採択新学術領域 「個性」創発脳

    • URL

      http://www.koseisouhatsu.jp

    • Related Report
      2016 Annual Research Report

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Published: 2016-07-04   Modified: 2022-01-27  

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