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Principles of pluripotent stem cells underlying plant vitality

Administrative Group

Project AreaPrinciples of pluripotent stem cells underlying plant vitality
Project/Area Number 17H06470
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionNara Institute of Science and Technology

Principal Investigator

Umeda Masaaki  奈良先端科学技術大学院大学, 先端科学技術研究科, 教授 (80221810)

Co-Investigator(Kenkyū-buntansha) 山口 信次郎  京都大学, 化学研究所, 教授 (10332298)
豊岡 公徳  国立研究開発法人理化学研究所, 環境資源科学研究センター, 上級技師 (10360596)
榊原 均  名古屋大学, 生命農学研究科, 教授 (20242852)
五島 剛太  名古屋大学, 理学研究科, 教授 (20447840)
林 誠  国立研究開発法人理化学研究所, 環境資源科学研究センター, チームリーダー (30291933)
蓑田 亜希子  国立研究開発法人理化学研究所, 生命医科学研究センター, チームリーダー (40721569)
鳥居 啓子  名古屋大学, トランスフォーマティブ生命分子研究所, 客員教授 (60506103)
佐竹 暁子  九州大学, 理学研究院, 教授 (70506237)
経塚 淳子  東北大学, 生命科学研究科, 教授 (90273838)
Project Period (FY) 2017-06-30 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥176,540,000 (Direct Cost: ¥135,800,000、Indirect Cost: ¥40,740,000)
Fiscal Year 2021: ¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2020: ¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
Fiscal Year 2019: ¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
Fiscal Year 2018: ¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2017: ¥109,720,000 (Direct Cost: ¥84,400,000、Indirect Cost: ¥25,320,000)
Keywords幹細胞 / 多能性 / 植物
Outline of Final Research Achievements

Our project aimed to understand the characteristics of plant stem cells, which support plant longevity and vitality, especially by focusing on their proliferative activity and pluripotency. To activate organic cooperation between research groups, we supported various activities including those involving animal scientists, thereby promoting collaborations. Besides, we conducted public relations activities to disseminate our research progress to Japan and abroad through international symposiums and via the homepage and newsletters.

Academic Significance and Societal Importance of the Research Achievements

国内の学会シンポジウム・ワークショップの企画、及び領域主催の国際シンポジウムの開催を通じて、領域研究の成果を国内外の研究者に広く発信できた。また、幹細胞研究会などを通じて動物研究者と交流する機会が増え、約70名の動物研究者との繋がりができた。これは今後発生生物学分野を開拓していく際に重要な基盤になると考えられる。さらに、若手研究者の海外相互派遣や様々なアウトリーチ活動を通じて、次世代の研究者育成にも貢献できた。

Report

(6 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (53 results)

All 2022 2021 2020 2019 2018 2017 Other

All Int'l Joint Research (26 results) Journal Article (11 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 10 results,  Open Access: 7 results) Presentation (13 results) (of which Int'l Joint Research: 3 results,  Invited: 7 results) Remarks (1 results) Funded Workshop (2 results)

  • [Int'l Joint Research] Gregor Mendel Institute(オーストリア)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] University of Massachusetts(米国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] University of Cambridge(英国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] VIB, Ghent University(ベルギー)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] University of Hamburg(ドイツ)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] Gregor Mendel Institute(オーストリア)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] University of Massachusetts(米国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] University of Cambridge(英国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] VIB, Ghent University(ベルギー)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] University of Hamburg(ドイツ)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Gregor Mendel Institute(オーストラリア)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] University of Massachusetts(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] University of Cambridge(英国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] VIB, Ghent University(ベルギー)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] University of Hamburg(ドイツ)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Gregor Mendel Institute(オーストラリア)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] University of Massachusetts(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] University of Cambridge(英国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] VIB, Ghent University(ベルギー)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] University of Hamburg(ドイツ)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Gregor Mendel Institute(オーストリア)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] University of Massachusetts(米国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] University of Cambridge(英国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] VIB, Ghent University(ベルギー)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] University of Hamburg(ドイツ)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Plant stem cell research is uncovering the secrets of longevity and persistent growth2021

    • Author(s)
      Umeda Masaaki、Ikeuchi Momoko、Ishikawa Masaki、Ito Toshiro、Nishihama Ryuichi、Kyozuka Junko、Torii Keiko U.、Satake Akiko、Goshima Gohta、Sakakibara Hitoshi
    • Journal Title

      The Plant Journal

      Volume: Online ahead of print Issue: 2 Pages: 1-10

    • DOI

      10.1111/tpj.15184

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Alterations in hormonal signals spatially coordinate distinct responses to DNA double-strand breaks in Arabidopsis roots2021

    • Author(s)
      Takahashi Naoki、Inagaki Soichi、Nishimura Kohei、Sakakibara Hitoshi、Antoniadi Ioanna、Karady Michal、Ljung Karin、Umeda Masaaki
    • Journal Title

      Science Advances

      Volume: 7 Issue: 25

    • DOI

      10.1126/sciadv.abg0993

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Regulation of the Plant Cell Cycle in Response to Hormones and the Environment2021

    • Author(s)
      Shimotohno Akie、Aki Shiori S.、Takahashi Naoki、Umeda Masaaki
    • Journal Title

      Annual Review of Plant Biology

      Volume: 72 Issue: 1 Pages: 72-78

    • DOI

      10.1146/annurev-arplant-080720-103739

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome Maintenance Mechanisms at the Chromatin Level2021

    • Author(s)
      Takatsuka Hirotomo、Shibata Atsushi、Umeda Masaaki
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 19 Pages: 10384-10384

    • DOI

      10.3390/ijms221910384

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] TheArabidopsisNRT1/PTR FAMILY protein NPF7.3/NRT1.5 is an indole-3-butyric acid transporter involved in root gravitropism2020

    • Author(s)
      Watanabe Shunsuke、Takahashi Naoki、Kanno Yuri、Suzuki Hiromi、Aoi Yuki、Takeda-Kamiya Noriko、Toyooka Kiminori、Kasahara Hiroyuki、Hayashi Ken-ichiro、Umeda Masaaki、Seo Mitsunori
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 117 Issue: 49 Pages: 31500-31509

    • DOI

      10.1073/pnas.2013305117

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] CDKD-dependent activation of CDKA;1 controls microtubule dynamics and cytokinesis during meiosis2020

    • Author(s)
      Sofroni Kostika、Takatsuka Hirotomo、Yang Chao、Dissmeyer Nico、Komaki Shinichiro、Hamamura Yuki、Bottger Lev、Umeda Masaaki、Schnittger Arp
    • Journal Title

      Journal of Cell Biology

      Volume: 219 Issue: 8

    • DOI

      10.1083/jcb.201907016

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A regulatory module controlling stress-induced cell cycle arrest in Arabidopsis2019

    • Author(s)
      Takahashi Naoki、Ogita Nobuo、Takahashi Tomonobu、Taniguchi Shoji、Tanaka Maho、Seki Motoaki、Umeda Masaaki
    • Journal Title

      eLife

      Volume: 8

    • DOI

      10.7554/elife.43944

    • NAID

      120006619181

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cytokinin signaling is essential for organ formation in Marchantia polymorpha2019

    • Author(s)
      Aki Shiori S、Mikami Tatsuya、Naramoto Satoshi、Nishihama Ryuichi、Ishizaki Kimitsune、Kojima Mikiko、Takebayashi Yumiko、Sakakibara Hitoshi、Kyozuka Junko、Kohchi Takayuki、Umeda Masaaki
    • Journal Title

      Plant and Cell Physiology

      Volume: 60 Issue: 8 Pages: 1842-1854

    • DOI

      10.1093/pcp/pcz100

    • NAID

      120006711216

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Editorial overview: How plants transform signaling cues into changes in gene expression2019

    • Author(s)
      Hwang Ildoo、Umeda Masaaki
    • Journal Title

      Current Opinion in Plant Biology

      Volume: 51 Pages: A1-A3

    • DOI

      10.1016/j.pbi.2019.09.006

    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Journal Article] Identifying the target genes of SUPPRESSOR OF GAMMA RESPONSE 1, a master transcription factor controlling DNA damage response in Arabidopsis.2018

    • Author(s)
      Ogita N, Okushima Y, Tokizawa M, Yamamoto YY, Tanaka M, Seki M, Makita Y, Matsui M, Okamoto-Yoshiyama K, Sakamoto T, Kurata T, Hiruma K, Saijo Y, Takahashi N, Umeda M.
    • Journal Title

      The Plant Journal

      Volume: - Issue: 3 Pages: 439-453

    • DOI

      10.1111/tpj.13866

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage2017

    • Author(s)
      Chen Poyu、Takatsuka Hirotomo、Takahashi Naoki、Kurata Rie、Fukao Yoichiro、Kobayashi Kosuke、Ito Masaki、Umeda Masaaki
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 635-635

    • DOI

      10.1038/s41467-017-00676-4

    • NAID

      120006354238

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Genome maintenance strategies in plant stem cells2022

    • Author(s)
      梅田正明、安喜史織、高橋直紀
    • Organizer
      第63回日本植物生理学会年会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 植物成長を制御する分子メカニズムの解明2021

    • Author(s)
      梅田正明
    • Organizer
      第38回日本植物バイオテクノロジー学会大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 細胞間コミュニケーションを介した植物幹細胞の維持機構2021

    • Author(s)
      梅田正明、杉山輝樹、紀平望帆
    • Organizer
      第44回日本分子生物学会年会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] オーキシンを介したヘテロクロマチン形成の制御機構2021

    • Author(s)
      安喜史織、梅田正明
    • Organizer
      第62回日本植物生理学会年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Comprehensive comparison of single-cell transcriptome analysis techniques in Arabidopsis root tissue2020

    • Author(s)
      Thomas Kelly、Nicola A. Hetherington、Kai Battenberg、Miho Kihira、Shiori Aki、Haruka Yabukami、Tsukasa Kouno、Masaaki Umeda、Makoto Hayashi、Aki Minoda
    • Organizer
      第43回日本分子生物学会年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] DNA損傷に応答した根の成長抑制におけるサイトカイニン合成の役割2020

    • Author(s)
      高橋直紀、Ioanna Antoniadi、Michal Karady、Karin Ljung、梅田正明
    • Organizer
      日本植物学会第84回大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Comparing technologies for single-cell transcriptome analysis in Arabidopsis thaliana root tissue2020

    • Author(s)
      Thomas Kelly, Nicola A. Hetherington, Kai Battenberg, Miho Kihira, Shiori S Aki, Haruka, Yabukami, Tsukasa Kouno, Masaaki Umeda, Makoto Hayashi and Aki Minoda
    • Organizer
      第61回日本植物生理学会年会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Comparing technologies for single-cell transcriptome analysis in Arabidopsis root tissue2019

    • Author(s)
      S. Thomas Kelly, Nicola A. Hetherington, Shiori Aki, Kai Battenberg, Haruka Yabukami, Tsukasa Kouno, Masaaki Umeda, Makoto Hayashi and Akiko Minoda
    • Organizer
      第42回日本分子生物学会年会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Genome maintenance strategies in stem cells2019

    • Author(s)
      梅田正明、安喜史織、高橋直紀
    • Organizer
      International Symposium: Principles of pluripotent stem cells underlying plant vitality
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Developing a single-cell bioinformatics analysis pipeline: Application of single-cell RNA-Seq to plant tissues2018

    • Author(s)
      S. Thomas Kelly, Nicola A. Hetherington, Shiori Aki, Haruka Yabukami, Kai Battenberg, Makoto Hayashi, Masaaki Umeda and Akiko Minoda
    • Organizer
      第41回日本分子生物学会年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Maintenance of genome integrity in root stem cells2017

    • Author(s)
      梅田正明
    • Organizer
      Taiwan-Japan Plant Biology 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Maintenance of genome integrity in root stem cells2017

    • Author(s)
      梅田正明
    • Organizer
      Plant Cell and Developmental Biology: Approaches to Multiscale Biosystems
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 植物幹細胞の神秘を探る2017

    • Author(s)
      梅田正明
    • Organizer
      植物科学シンポジウム2017:植物科学のバイオ農業への展開
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Remarks] 領域ホームページ

    • URL

      http://www.plant-stem-cells.jp

    • Related Report
      2021 Annual Research Report 2020 Annual Research Report 2019 Annual Research Report 2018 Annual Research Report 2017 Annual Research Report
  • [Funded Workshop] Secrets of stem cells underlying longevity and persistent growth in plants2021

    • Related Report
      2021 Annual Research Report
  • [Funded Workshop] International Symposium: Principles of pluripotent stem cells underlying plant vitality2019

    • Related Report
      2019 Annual Research Report

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Published: 2017-07-04   Modified: 2023-01-30  

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