| Project Area | Principles of memory dynamism elucidated from a diversity of learning systems |
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| Project/Area Number |
25115001
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| Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
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| Allocation Type | Single-year Grants |
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| Review Section |
Biological Sciences
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| Research Institution | Tokyo Metropolitan Institute of Medical Science |
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Principal Investigator |
SAITOE Minoru 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 基盤技術研究センター長 (50261839)
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| Co-Investigator(Kenkyū-buntansha) |
佐藤 守俊 東京大学, 大学院総合文化研究科, 教授 (00323501)
多羽田 哲也 東京大学, 分子細胞生物学研究所, 教授 (10183865)
久恒 辰博 東京大学, 新領域創成科学研究科, 准教授 (10238298)
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| Co-Investigator(Renkei-kenkyūsha) |
IINO Yuichi 東京大学, 理学系研究科, 教授 (40192471)
YOSHIHARA Yoshihiro 理化学研究所, 脳科学総合研究センター・システム分子行動学研究チーム, チームリーダー (20220717)
KAMIKOUCHI Azusa 名古屋大学, 理学研究科, 教授 (00525264)
ISHIHARA Takeshi 九州大学, 理学研究院, 教授 (10249948)
INOKUCHI Kaoru 富山大学, 医学薬学研究部, 教授 (20318827)
MATSUO Naoki 大阪大学, 医学系研究科, 准教授 (10508956)
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| Project Period (FY) |
2013-06-28 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥245,310,000 (Direct Cost: ¥188,700,000、Indirect Cost: ¥56,610,000)
Fiscal Year 2017: ¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2016: ¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2015: ¥20,020,000 (Direct Cost: ¥15,400,000、Indirect Cost: ¥4,620,000)
Fiscal Year 2014: ¥36,140,000 (Direct Cost: ¥27,800,000、Indirect Cost: ¥8,340,000)
Fiscal Year 2013: ¥155,350,000 (Direct Cost: ¥119,500,000、Indirect Cost: ¥35,850,000)
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| Keywords | 記憶 / 動物モデル / 神経回路 / 流動性 / 共通原理 / 神経科学 / シグナル伝達 / 行動学 / 脳・神経 / 学習・記憶 |
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| Outline of Final Research Achievements |
Memory is dynamic and memory mechanism is changed depending on internal and external condition. In our research area, we have studied how such dynamics of memory and plasticity of memory mechanisms occur. To this end we employed a combination of different animal models, each of which has useful phenotypes and methodological advantages in areas of memory research. We had annual meetings, workshops and international symposium to exchange our findings and promote discussion timely. We also had young scientists symposium to give a chance to young scientists to appeal their findings and significance of their research. Accordingly, we have identified memory principle commonly used in most organisms, as well as mechanism that are specific to a particular organism. Hence, we have made great advances in the concept of memory dynamism and results from our research area have been published in number of prestige and high impact journals.
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