| Budget Amount *help |
¥43,160,000 (Direct Cost: ¥33,200,000、Indirect Cost: ¥9,960,000)
Fiscal Year 2019: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2018: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2017: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2016: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2015: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
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| Outline of Final Research Achievements |
The purpose of this project is to contribute to the construction of a precisly controlled reaction field through the analysis of catalytic mechanisms in biocatalysts and similar reaction fields. We have developed a method for determining the reaction pathways through inter-system crossings in biocatalytic reactions, applied to the reaction mechanism of molecular adsorption in some metal complexes, and proposed guidelines for the ligand design. We also studied the inter-system crossing mechanisms of the catalytic reactions exhibited by myoglobin and, together with an experimental group, elucidated the origin of the catalytic activity exhibited by reconstituted myoglobin. In addition, we have collaborated on the analysis of reaction mechanisms through the collaborative researches and have clarified the physicochemical characteristics of a number of excellent catalytic systems. As a result, we were able to publish 38 original papers (including 13 in the area).
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