| Budget Amount *help |
¥118,040,000 (Direct Cost: ¥90,800,000、Indirect Cost: ¥27,240,000)
Fiscal Year 2019: ¥21,320,000 (Direct Cost: ¥16,400,000、Indirect Cost: ¥4,920,000)
Fiscal Year 2018: ¥21,320,000 (Direct Cost: ¥16,400,000、Indirect Cost: ¥4,920,000)
Fiscal Year 2017: ¥21,320,000 (Direct Cost: ¥16,400,000、Indirect Cost: ¥4,920,000)
Fiscal Year 2016: ¥21,320,000 (Direct Cost: ¥16,400,000、Indirect Cost: ¥4,920,000)
Fiscal Year 2015: ¥32,760,000 (Direct Cost: ¥25,200,000、Indirect Cost: ¥7,560,000)
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| Outline of Final Research Achievements |
A multi-dimensional and multi-level modal shift and its mechanism including oscillation modalities such as transition from membrane potential oscillation to Ca2+ oscillation, nerve cell oscillation becoming cell population oscillation and generating a rhythm component of EEG via neural circuit synchronization, and of which mechanisms were studied by means of animal experiments based on GABA-Cl- homeodynamics theory. We tried and elucidated some of the underlying mechanism of such as: functions of molecules that induce certain types of epilepsy, excitatory GABA that influences cycles of hormone secretion, genes responsible for excessive nerve binding to dopamine neurons, changes in oscillatory phenomena due to phosphorylation of Cl- transporter, GABA synapses related to γ oscillation, effects of static magnetic field stimulation on cerebrocortical neural circuit function, and modeling of the modal shift mechanism by which neuronal oscillation cause a network pathology.
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