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Neural mechanism of affective response with Shitsukan perception

Planned Research

Project AreaUnderstanding human recognition of material properties for innovation in SHITSUKAN science and technology
Project/Area Number 15H05917
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionNational Institutes for Quantum and Radiological Science and Technology

Principal Investigator

Minamimoto Takafumi  国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 脳機能イメージング研究部, グループリーダー(定常) (50506813)

Co-Investigator(Kenkyū-buntansha) 本田 学  国立研究開発法人国立精神・神経医療研究センター, 神経研究所 疾病研究第七部, 部長 (40321608)
鯉田 孝和  豊橋技術科学大学, エレクトロニクス先端融合研究所, 准教授 (10455222)
Project Period (FY) 2015-06-29 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥81,250,000 (Direct Cost: ¥62,500,000、Indirect Cost: ¥18,750,000)
Fiscal Year 2019: ¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
Fiscal Year 2018: ¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
Fiscal Year 2017: ¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
Fiscal Year 2016: ¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Fiscal Year 2015: ¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Keywords質感 / 価値判断 / DREADDs / サル / エンリッチメント / 脳・神経 / 認知科学 / 神経科学 / 情動
Outline of Final Research Achievements

We studied the neural mechanism of affective/motivational responses, especially those underlying neural circuits and value-coding mechanisms. We developed a novel method for dissecting specific neural circuits in behaving monkeys, identifying the specific role of distinct front-subcortical circuits in value-based decision-making. Using this method, we also identified the neural circuit for value judgement and emotional processing. Regarding the identification of texture attributes that affect specific emotional responses, we found a life-prolonging effect of the complexity of environmental information containing natural environmental sounds recorded in tropical rain forests and the effect is mediated by reduction of social stress. We also characterized asymmetric information processing in dark/brightness which might be involved in the preference of brightness and vividness.

Academic Significance and Societal Importance of the Research Achievements

「質感の知覚から価値・情動への変換」が脳のどこで行われているか?の「地図」(脳回路)が分かり、さらに地図上の道を「一時通行止め」にする手法(経路選択操作)が確立できた。これらを組み合わせることで、今後それぞれの道でどのような「荷物の積み下ろし」がされているか?(情報変換プロセス)という、感性的質感認知の重要かつ本質的な仕組みについて、その理解が一層進むものと期待される。さらに研究成果の応用として “超高周波音響”が脳の報酬系を活性化させる作用に着目し、うつ病の快楽消失などの症状を改善するための治療プロトコルを開発し、臨床応用への道を拓いた。

Report

(6 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (84 results)

All 2020 2019 2018 2017 2016 2015 Other

All Int'l Joint Research (5 results) Journal Article (40 results) (of which Int'l Joint Research: 11 results,  Peer Reviewed: 40 results,  Open Access: 27 results,  Acknowledgement Compliant: 2 results) Presentation (29 results) (of which Int'l Joint Research: 14 results,  Invited: 16 results) Book (3 results) Remarks (3 results) Patent(Industrial Property Rights) (3 results) Funded Workshop (1 results)

  • [Int'l Joint Research] National Institute of Health/Univ. North Carolina/Icahn School of Medicine at Mount Sinai(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] NIH/U. South Carolina/Mount Sinai(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] National Institute of Health(U.S.A.)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] National Institute of Health(米国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] Nathional Institute of Health(米国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys.2020

    • Author(s)
      Nagai Y, Miyakawa N, Takuwa H, Hori Y, Oyama K, Ji B, Takahashi M, Huang XP, Slocum ST, DiBerto JF, Xiong Y, Urushihata T, Hirabayashi T, Fujimoto A, Mimura K, English JG, Liu J, Inoue K, Kumata K, Seki C, Ono M, Shimojo M, Zhang MR, Tomita Y, Suhara T, Takada M, Higuchi M, Jin J, Roth BL, Minamimoto T
    • Journal Title

      Nature Neuroscience

      Volume: -

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Macaques Exhibit Implicit Gaze Bias Anticipating Others’ False-Belief-Driven Actions via Medial Prefrontal Cortex2020

    • Author(s)
      Hayashi Taketsugu、Akikawa Ryota、Kawasaki Keisuke、Egawa Jun、Minamimoto Takafumi、Kobayashi Kazuto、Kato Shigeki、Hori Yukiko、Nagai Yuji、Iijima Atsuhiko、Someya Toshiyuki、Hasegawa Isao
    • Journal Title

      Cell Reports

      Volume: 30 Issue: 13 Pages: 4433-4444

    • DOI

      10.1016/j.celrep.2020.03.013

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Revealing Relationships Among Cognitive Functions Using Functional Connectivity and a Large-Scale Meta-Analysis Database2020

    • Author(s)
      Kurashige Hiroki、Kaneko Jun、Yamashita Yuichi、Osu Rieko、Otaka Yohei、Hanakawa Takashi、Honda Manabu、Kawabata Hideaki
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 13 Pages: 457-457

    • DOI

      10.3389/fnhum.2019.00457

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Flexible parylene-thread bioprobe and the sewing method for in vivo neuronal recordings2020

    • Author(s)
      Yamashita Koji、Sawahata Hirohito、Yamagiwa Shota、Morikawa Yusuke、Numano Rika、Koida Kowa、Kawano Takeshi
    • Journal Title

      Sensors and Actuators B: Chemical

      Volume: - Pages: 127835-127835

    • DOI

      10.1016/j.snb.2020.127835

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Trait and State-Dependent Risk Attitude of Monkeys Measured in a Single-Option Response Task2019

    • Author(s)
      Fujimoto Atsushi、Minamimoto Takafumi
    • Journal Title

      Frontiers in Neuroscience

      Volume: 13 Pages: 816-816

    • DOI

      10.3389/fnins.2019.00816

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Augmentation of Positive Valence System?Focused Cognitive Behavioral Therapy by Inaudible High-Frequency Sounds for Anhedonia2019

    • Author(s)
      Ito Masaya、Miyamae Mitsuhiro、Yokoyama Chika、Yamashita Yuichi、Ueno Osamu、Maruo Kazushi、Komazawa Asami、Niwa Madoka、Honda Manabu、Horikoshi Masaru
    • Journal Title

      JAMA Network Open

      Volume: 2 Issue: 11 Pages: e1915819-e1915819

    • DOI

      10.1001/jamanetworkopen.2019.15819

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effective Augmentation of Creativity-Involving Productivity Consequent to Spontaneous Selectivity in Knowledge Acquisition2019

    • Author(s)
      Kurashige Hiroki、Yamashita Yuichi、Hanakawa Takashi、Honda Manabu
    • Journal Title

      Frontiers in Psychology

      Volume: 10 Pages: 600-600

    • DOI

      10.3389/fpsyg.2019.00600

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reciprocal cortical activation patterns during incisal and molar biting correlated with bite force levels: an fMRI study2019

    • Author(s)
      Yoshizawa Hideyuki、Miyamoto Jun J.、Hanakawa Takashi、Shitara Hitoshi、Honda Manabu、Moriyama Keiji
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 8419-8419

    • DOI

      10.1038/s41598-019-44846-4

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Donut‐Shaped Stretchable Kirigami: Enabling Electronics to Integrate with the Deformable Muscle2019

    • Author(s)
      Morikawa Yusuke、Yamagiwa Shota、Sawahata Hirohito、Numano Rika、Koida Kowa、Kawano Takeshi
    • Journal Title

      Advanced Healthcare Materials

      Volume: 8 Issue: 23 Pages: 1900939-1900939

    • DOI

      10.1002/adhm.201900939

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Signaling Incentive and Drive in the Primate Ventral Pallidum for Motivational Control of Goal-Directed Action2019

    • Author(s)
      Fujimoto Atsushi、Hori Yukiko、Nagai Yuji、Kikuchi Erika、Oyama Kei、Suhara Tetsuya、Minamimoto Takafumi
    • Journal Title

      The Journal of Neuroscience

      Volume: 39 Issue: 10 Pages: 1793-1804

    • DOI

      10.1523/jneurosci.2399-18.2018

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Abnormal axon guidance signals and reduced interhemispheric connection via anterior commissure in neonates of marmoset ASD model2019

    • Author(s)
      Mimura K, Oga T, Sasaki T, Nakagaki K, Sato C, Sumida K, Hoshino K, Saito K, Miyawaki I, Suhara T, Aoki I, Minamimoto T, Ichinohe N
    • Journal Title

      NeuroImage

      Volume: 印刷中 Pages: 243-251

    • DOI

      10.1016/j.neuroimage.2019.04.006

    • NAID

      120007133606

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Magnetically Assembled High-Aspect-Ratio Needle Electrode for Recording Neuronal Activity2019

    • Author(s)
      Yasui Taiki、Yamagiwa Shota、Sawahata Hirohito、Idogawa Shinnosuke、Kubota Yoshihiro、Kita Yuto、Yamashita Koji、Numano Rika、Koida Kowa、Kawano Takeshi
    • Journal Title

      Advanced Healthcare Materials

      Volume: 8 Issue: 5 Pages: 1801081-1801081

    • DOI

      10.1002/adhm.201801081

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Color Perception in Protanomalous Female Macaca fascicularis2019

    • Author(s)
      Widayati Kanthi A.、Saito Atsuko、Suryobroto Bambang、Mikami Akichika、Koida Kowa
    • Journal Title

      i-Perception

      Volume: 10 Issue: 2 Pages: 204166951984613-204166951984613

    • DOI

      10.1177/2041669519846136

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Ventral striatum links motivational and motor networks during operant-conditioned movement in rats2019

    • Author(s)
      Hori Yuki、Ihara Naoki、Sugai Chiaki、Ogura Jun、Honda Manabu、Kato Koichi、Isomura Yoshikazu、Hanakawa Takashi
    • Journal Title

      NeuroImage

      Volume: 184 Pages: 943-953

    • DOI

      10.1016/j.neuroimage.2018.10.018

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neuroanatomical Basis of Individuality in Muscle Tuning Function: Neural Correlates of Muscle Tuning2019

    • Author(s)
      Kahori Kita,Rieko Osu,Chihiro Hosoda,Manabu Honda,Takashi Hanakawa,Jun Izawa
    • Journal Title

      Frontiers in Behavioral Neuroscience

      Volume: 13:28 Pages: 00028-00028

    • DOI

      10.3389/fnbeh.2019.00028

    • NAID

      120007127915

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Recruitment of calbindin into nigral dopamine neurons protects against drug-induced parkinsonism. Mov Disord [Epub ahead of print] doi: 10.1002/mds.1072018

    • Author(s)
      Inoue K, Miyachi S, Nishi K, Okado H, Nagai Y, Minamimoto T, Nambu A, Takada M
    • Journal Title

      Mov Disord

      Volume: - Issue: 2 Pages: 200-209

    • DOI

      10.1002/mds.107

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Induction of prolonged natural lifespans in mice exposed to acoustic environmental enrichment2018

    • Author(s)
      Yamashita Yuichi、Kawai Norie、Ueno Osamu、Matsumoto Yui、Oohashi Tsutomu、Honda Manabu
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 7909-7909

    • DOI

      10.1038/s41598-018-26302-x

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Gender-specific associations of depression and anxiety symptoms with mental rotation.2018

    • Author(s)
      Oshiyama C, Sutoh C, Miwa H, Okabayashi S, Hamada H, Matsuzawa D, Hirano Y, Takahashi T, Niwa S, Honda M, Sakatsume K, Nishimura T, Shimizu E
    • Journal Title

      J Affect Disord, in press

      Volume: - Pages: 277-284

    • DOI

      10.1016/j.jad.2018.04.006

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Initial experience with a sensorimotor rhythmbased brain-computer interface in a Parkinson’s disease patient2018

    • Author(s)
      Kazumi Kasahara, Hideki Hoshino, Yoshihiko Furusawa, Charles Sayo DaSalla, Manabu Honda, Miho Murata, Takashi Hanakawa
    • Journal Title

      Brain-Computer Interfaces

      Volume: 印刷中 Issue: 2-3 Pages: 88-96

    • DOI

      10.1080/2326263x.2018.1440781

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mortal Organisms Rescue Immortal Organisms from Evolutionary Inertness: Perspective of the Programmed Self-decomposition Model2018

    • Author(s)
      Maekawa Tadao、Honda Manabu、Ueno Osamu、Oohashi Tsutomu
    • Journal Title

      TPNC 2018. Lecture Notes in Computer Science

      Volume: ー Pages: 279-291

    • DOI

      10.1007/978-3-030-04070-3_22

    • ISBN
      9783030040697, 9783030040703
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dependence of behavioral performance on material category in an object grasping task with monkeys2018

    • Author(s)
      Yokoi Isao、Tachibana Atsumichi、Minamimoto Takafumi、Goda Naokazu、Komatsu Hidehiko
    • Journal Title

      Journal of Neurophysiology

      Volume: 印刷中 Issue: 2 Pages: 553-563

    • DOI

      10.1152/jn.00748.2017

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies2018

    • Author(s)
      Ran Cheng, Wakana Mori, Longle Ma, Mireille Alhouayek, Akiko Hatori, Yiding Zhang, Daisuke Ogasawara, Gengyang Yuan, Zhen Chen, Xiaofei Zhang, Hang Shi, Tomoteru Yamasaki, Lin Xie, Katsushi Kumata, Masayuki Fujinaga, Yuji Nagai, Takafumi Minamimoto, Mona Svensson, Lu Wang, Yunfei Du, Mary Jo Ondrechen, Neil Vasdev
    • Journal Title

      J. Med. Chem.

      Volume: 61 Issue: 6 Pages: 2278-2291

    • DOI

      10.1021/acs.jmedchem.7b01400

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A Knowledge-Based Arrangement of Prototypical Neural Representation Prior to Experience Contributes to Selectivity in Upcoming Knowledge Acquisition2018

    • Author(s)
      Kurashige Hiroki、Yamashita Yuichi、Hanakawa Takashi、Honda Manabu
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 12

    • DOI

      10.3389/fnhum.2018.00111

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fiber bundle endomicroscopy with multi-illumination for three-dimensional reflectance image reconstruction2018

    • Author(s)
      Ando Yoriko、Sawahata Hirohito、Kawano Takeshi
    • Journal Title

      Journal of Biomedical Optics

      Volume: 23 Issue: 02 Pages: 1-1

    • DOI

      10.1117/1.jbo.23.2.020502

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ultrastretchable Kirigami Bioprobes2018

    • Author(s)
      Morikawa Yusuke、Yamagiwa Shota、Sawahata Hirohito、Numano Rika、Koida Kowa、Ishida Makoto、Kawano Takeshi
    • Journal Title

      Advanced Healthcare Materials

      Volume: 7 Issue: 3 Pages: 1701100-1701100

    • DOI

      10.1002/adhm.201701100

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Long nanoneedle-electrode devices for extracellular and intracellular recording in vivo2018

    • Author(s)
      Kubota Yoshihiro、Yamagiwa Shota、Sawahata Hirohito、Idogawa Shinnosuke、Tsuruhara Shuhei、Numano Rika、Koida Kowa、Ishida Makoto、Kawano Takeshi
    • Journal Title

      Sensors and Actuators B: Chemical

      Volume: 258 Pages: 1287-1294

    • DOI

      10.1016/j.snb.2017.11.152

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Roles of centromedian parafascicular nuclei of thalamus and cholinergic interneurons in the dorsal striatum in associative learning of environmental events.2017

    • Author(s)
      Yamanaka K, Hori Y, Minamimoto T, Yamada H, Matsumoto N, Enomoto K, Aosaki T, Graybiel AM, Kimura M.
    • Journal Title

      J Neural Transm (Vienna).

      Volume: 21 Issue: 3 Pages: 1-13

    • DOI

      10.1007/s00702-017-1713-z

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Electroencephalogram characteristics during possession trances in healthy individuals2017

    • Author(s)
      Kawai Norie、Honda Manabu、Nishina Emi、Yagi Reiko、Oohashi Tsutomu
    • Journal Title

      NeuroReport

      Volume: 28 Issue: 15 Pages: 949-955

    • DOI

      10.1097/wnr.0000000000000857

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Task-dependent recurrent dynamics in visual cortex2017

    • Author(s)
      Tajima Satohiro、Koida Kowa、Tajima Chihiro I、Suzuki Hideyuki、Aihara Kazuyuki、Komatsu Hidehiko
    • Journal Title

      eLife

      Volume: 6

    • DOI

      10.7554/elife.26868

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation.2016

    • Author(s)
      Nagai Y, Kikuchi E, Lerchner W, Inoue Ki, Ji B, Eldridge MA, Kaneko H, Kimura Y, Oh-Nishi A, Hori Y, Kato Y, Hirabayashi T, Fujimoto A, Kumata K, Zhang MR, Aoki I, SuharaT, Higuchi M, Takada M, Richmond BJ, Minamimoto T.
    • Journal Title

      Nature Communications

      Volume: 7 Issue: 1 Pages: 13605-13605

    • DOI

      10.1038/ncomms13605

    • NAID

      120005898960

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] DREADD-expressing neurons in living brain and their application to implantation of iPSC-derived neuroprogenitors.2016

    • Author(s)
      Ji B, Kaneko H, Minamimoto T, Inoue H, Takeuchi H, Kumata K, Zhang MR, Aoki I, Seki C, Ono M, Tokunaga M, Tsukamoto S, Tanabe K, Shin RM, Minamihisamatsu T, Kito S, Richmond BJ, Suhara T, Higuchi M.
    • Journal Title

      J. Neuroscience

      Volume: 36 Issue: 45 Pages: 11544-11558

    • DOI

      10.1523/jneurosci.1279-16.2016

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Single 5μm diameter needle electrode block modules for unit recordings in vivo2016

    • Author(s)
      H. Sawahata, S. Yamagiwa, A. Moriya, T. Dong, H. Oi, Y. Ando, R. Numano, M. Ishida, K. Koida & T. Kawano
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 35806-35806

    • DOI

      10.1038/srep35806

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Development of TASP0410457 (TASP457), a novel dihydroquinolinone derivative as a PET radioligand for central histamine H3 receptors2016

    • Author(s)
      Kazumi Koga, Jun Maeda, Masaki Tokunaga, Masayuki Hanyu, Kazunori Kawamura, Mari Ohmichi, Toshio Nakamura, Yuji Nagai, Chie Seki, Yasuyuki Kimura, Takafumi Minamimoto, Ming-Rong Zhang, Toshimitsu Fukumura, Tetsuya Suhara, Makoto Higuchi
    • Journal Title

      EJNMMI Research

      Volume: 6 Issue: 1 Pages: 1-14

    • DOI

      10.1186/s13550-016-0170-2

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Synthesis and preclinical evaluation of sulfonamido-based [11C-Carbonyl]-carbamates and ureas for imaging monoacylglycerol lipase.2016

    • Author(s)
      Wang L, Mori W, Cheng R, Yui J, Hatori A, Ma L, Zhang Y, Rotstein BH, Fujinaga M, Shimoda Y, Yamasaki T, Xie L, Nagai Y, Minamimoto T, Higuchi M, Vasdev N, Zhang MR, Liang SH.
    • Journal Title

      Theranostics

      Volume: 6(8) Issue: 8 Pages: 1145-1159

    • DOI

      10.7150/thno.15257

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Characteristics of fast-spiking neurons in the striatum of behaving monkeys.2016

    • Author(s)
      Yamada H, Inokawa H, Hori Y, Pan X, Matsuzaki R, Nakamura K, Samejima K, Shidara M, Kimura M, Sakagami M, Minamimoto T.
    • Journal Title

      Neurosci Res.

      Volume: 105 Pages: 2-18

    • DOI

      10.1016/j.neures.2015.10.003

    • NAID

      120007135484

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A primary role for nucleus accumbens and related limbic network in vocal tics.2016

    • Author(s)
      McCairn KW, Nagai Y, Hori Y, Ninomiya T, Kikuchi E, Lee J-Y, Suhara T, Iriki A, Minamimoto T, Takada M, Isoda M, Matsumoto M
    • Journal Title

      Neuron

      Volume: 89 Issue: 2 Pages: 300-307

    • DOI

      10.1016/j.neuron.2015.12.025

    • NAID

      120005997652

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Crossmodal association of visual and haptic material properties of objects in the monkey ventral visual cortex2016

    • Author(s)
      Goda N, Yokoi I, Tachibana A, Minamimoto T, Komatsu H
    • Journal Title

      Current Biology

      Volume: 26 Issue: 7 Pages: 928-934

    • DOI

      10.1016/j.cub.2016.02.003

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Development of a removable head fixation device for longitudinal behavioral and imaging studies in rats.2016

    • Author(s)
      Hori Y, Ogura J, Ihara N, Higashi T, Tashiro T, Honda M, Hanakawa T.
    • Journal Title

      J Neurosci Methods

      Volume: 264 Pages: 11-15

    • DOI

      10.1016/j.jneumeth.2016.02.014

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Brain-targeted co-delivery of therapeutic gene and peptide by multifunctional nanoparticles in Alzheimer's disease mice2015

    • Author(s)
      Liu Y, An S, Li J, Kuang Y, He X, Guo Y, Ma H, Zhang Y, Ji B, Jiang C.
    • Journal Title

      Biomaterials

      Volume: 88 Issue: 1 Pages: 33-45

    • DOI

      10.1038/nn.4192

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Noninvasive quantification of cerebral metabolic rate for glucose in rats using (18)F-FDG PET and standard input function.2015

    • Author(s)
      Hori Y, Ihara N, Teramoto N, Kunimi M, Honda M, Kato K, Hanakawa T
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: 35 Issue: 10 Pages: 1664-1670

    • DOI

      10.1038/jcbfm.2015.104

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 化学遺伝学とイメージングの融合による霊長類脳回路の可視化と操作2020

    • Author(s)
      南本敬史
    • Organizer
      第9回マーモセット研究会大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] DREADD inactivation reveals critical role of orbitofrontal cortex in reward-based adaptive decision-making in monkeys.2019

    • Author(s)
      Oyama K, Hori Y, Nagai Y, Hirabayashi T, Miyakawa N, Fujimoto A, Mimura K, Inoue K, Eldridge MAG, Saunders RC, Suhara T, Takada M, Higuchi M, Richmond BJ, Minamimoto T.
    • Organizer
      第42回日本神経科学大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] New DREADD compound enables to visualize and manipulate neural circuits in monkeys2019

    • Author(s)
      Minamimoto T
    • Organizer
      NIH BRAIN Initiative Chemogenetic Innovations in the Manipulation and Monitoring of Labeled Neurons Workshop
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Chemogenetic activation of the amygdala specifically disrupts the representation of socio-emotional information in the macaque ventral visual cortex.2019

    • Author(s)
      Miyakawa N, Nagai Y, Hori Y, Matsuo T, Suzuki T, Inoue K, Takada M, Suhara T, Kawasaki K, and Minamimoto T.
    • Organizer
      第42回日本神経科学大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 超高密度メディア情報を用いた情報環境医療の開発2019

    • Author(s)
      本田学
    • Organizer
      日本機械学会シンポジウム
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Large enhancement of simultaneous color contrast by surrounding white gap, but not by black gap2019

    • Author(s)
      Tama Kanematsu, Kowa Koida
    • Organizer
      Vision Science Society
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Remote simultaneous color contrast and assimilation effects across the l-m cone axis2019

    • Author(s)
      Tama Kanematsu, Kowa Koida
    • Organizer
      ICVS 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Fine marking method of metal microelectrode for the electrophysiological recording in vivo2019

    • Author(s)
      K. KOIDA, H. SAWAHATA, R. NUMANO, T. KAWANO, T. HARA
    • Organizer
      SfN 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 網膜から初期視覚野における神経生理学的基盤2019

    • Author(s)
      鯉田孝和
    • Organizer
      第21回日本感性工学会大会
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A chemogenetic toolbox for primates2019

    • Author(s)
      Minamimoto T.
    • Organizer
      International Symposium of Brain/MINDs (ISBM2019)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] PET imaging of selective control of neural activity with a novel DREADD agonist2018

    • Author(s)
      Nagai Y, ほか26名, Minamimoto T.
    • Organizer
      第41回日本神経科学大会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] PET imaging-guided chemogenetic modification of reward-related circuits in monkeys2018

    • Author(s)
      Minamimoto T.
    • Organizer
      第41回日本神経科学大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] An object's material properties provide motion cues to three-dimensional shape2018

    • Author(s)
      Masakazu Ohara, Juno Kim, Kowa Koida
    • Organizer
      Vision Science Society
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 物体の奥行き知覚に光沢と透明特性が与える影響2018

    • Author(s)
      Masakazu Ohara, Juno Kim, Kowa koida
    • Organizer
      質感のつどい 第4回公開フォーラム
    • Related Report
      2018 Annual Research Report
  • [Presentation] Introduction; A La Medecine Informative Pour Les Troubles Psychiatriques/Neurologiques.2018

    • Author(s)
      Manabu Honda
    • Organizer
      11e Colloque Approches Non-Medicamenteuses.
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 感性的質感認知のしくみをサル脳科学の先端技術で探る2018

    • Author(s)
      Minamimoto T.
    • Organizer
      質感のつどい 第4回公開フォーラム
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] PET imaging-guided chemogenetic manipulation of reward-related circuits in monkeys.2018

    • Author(s)
      Takafumi Minamimoto
    • Organizer
      Advances in Brain Neuromodulation
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 高輝度大画面ディスプレイを用いた強い青色光刺激による持続的瞳孔反射2017

    • Author(s)
      田中孝治,鯉田孝和
    • Organizer
      日本視覚学会2017年冬季大会
    • Place of Presentation
      NHK放送技術研究所, 東京
    • Year and Date
      2017-01-18
    • Related Report
      2016 Annual Research Report
  • [Presentation] Neural and molecular mechanisms underlying loss of motivation in monkeys.2017

    • Author(s)
      Takafumi Minamimoto
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] PET imaging-guided chemogenetic modification of reward-related circuits in monkeys.2017

    • Author(s)
      Takafumi Minamimoto
    • Organizer
      BRAIN2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Hyper color contrast illusion (HCC), large enhancement of simultaneous color contrast by bordering white line2017

    • Author(s)
      Tama Kanematsu, Kowa Koida
    • Organizer
      THE 24TH SYMPOSIUM OF THE INTERNATIONAL COLOUR VISION SOCIETY
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 情報環境から脳の健康に迫る新たな戦略「情報医療」の可能性2017

    • Author(s)
      本田 学
    • Organizer
      第27回日本病態生理学会大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 動機付け制御とその障害におけるドーパミンの役割2016

    • Author(s)
      南本敬史
    • Organizer
      日本大脳基底核研究会
    • Place of Presentation
      秋田温泉, 秋田
    • Year and Date
      2016-07-23
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] PETイメージングと化学遺伝学的手法の融合によるサル脳科学研究の展開2016

    • Author(s)
      南本敬史
    • Organizer
      平成27年度 京都大学霊長類研究所共同利用研究会
    • Place of Presentation
      京都大学霊長類研究所
    • Year and Date
      2016-03-11
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 脳にやさしい健康住宅.2016

    • Author(s)
      本田 学
    • Organizer
      三重県庁健康住宅に係る研究会
    • Place of Presentation
      三重県津市
    • Year and Date
      2016-02-14
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Acoustic environmental enrichment prolonged natural lifespan of mice.2016

    • Author(s)
      Yamashita Y, Kawai N, Ueno O, Oohashi T, Honda M
    • Organizer
      Annual Meeting of Society for Neuroscience 2016
    • Place of Presentation
      San Diego, USA
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 音楽と脳:耳に聞こえない高周波が音楽の感動を高める.2015

    • Author(s)
      本田 学
    • Organizer
      平成27年度第3回旭化成守山支社講演会
    • Place of Presentation
      滋賀県守山市
    • Year and Date
      2015-12-04
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] The role of dopamine and serotonin in value-based decision-making in normal and disease state.2015

    • Author(s)
      Takafumi Minamimoto
    • Organizer
      Symposium on Prediction and Decision Making 2015.
    • Place of Presentation
      東京大学
    • Year and Date
      2015-10-30
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 脳を知る:耳に聞こえない高周波が音楽の感動を高める.2015

    • Author(s)
      本田 学
    • Organizer
      脳の世紀シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2015-09-16
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Book] 業界別:2019年大予測 人間の欲求 (2019年1月13日)「テクノロジーが発展する未来。人間の欲求は変わるのか。」2019

    • Author(s)
      本田学
    • Publisher
      Web出版 https://newspicks.com/news/3592289/
    • Related Report
      2018 Annual Research Report
  • [Book] 音楽と脳、編著:NPO法人 脳の世紀推進会議2016

    • Author(s)
      本田 学
    • Total Pages
      156
    • Publisher
      クバプロ
    • Related Report
      2016 Annual Research Report
  • [Book] 感性と情動を生み出す脳(書名:質感の科学、小松英彦編)2016

    • Author(s)
      本田 学
    • Total Pages
      231
    • Publisher
      朝倉書店
    • Related Report
      2016 Annual Research Report
  • [Remarks] システム神経回路研究グループ

    • URL

      https://www.nirs.qst.go.jp/seika/brain/team/system_09.html

    • Related Report
      2019 Annual Research Report
  • [Remarks] 放射線医学総合研究所 脳機能イメージング研究部 システム神経回路研究チーム

    • URL

      http://www.nirs.qst.go.jp/seika/brain/team/system_09.html

    • Related Report
      2017 Annual Research Report
  • [Remarks] システム神経回路研究チーム

    • URL

      http://www.nirs.qst.go.jp/seika/brain/team/system_09.html

    • Related Report
      2016 Annual Research Report
  • [Patent(Industrial Property Rights)] 人工受容体に結合する新規化合物、人工受容体のイメージング方法、アゴニストまたはアンタゴニスト、治療薬、コンパニオン診断薬、神経細胞のイメージング方法2018

    • Inventor(s)
      南本敬史・永井裕司・季斌・宮川尚久・樋口真人・須原哲也
    • Industrial Property Rights Holder
      量子科学技術研究開発機構
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-118210
    • Filing Date
      2018
    • Related Report
      2018 Annual Research Report
  • [Patent(Industrial Property Rights)] プローブ刺入デバイス、プローブ刺入デバイスの挿入方法、及び電気信号取得方法2018

    • Inventor(s)
      鯉田孝和、澤畑博人、河野剛士、山際翔太、櫻井省花子
    • Industrial Property Rights Holder
      豊橋技術科学大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-091400
    • Filing Date
      2018
    • Related Report
      2018 Annual Research Report
  • [Patent(Industrial Property Rights)] 電極及びその用途2017

    • Inventor(s)
      澤畑博人、鯉田孝和
    • Industrial Property Rights Holder
      豊橋技術科学大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-241054
    • Filing Date
      2017
    • Related Report
      2017 Annual Research Report
  • [Funded Workshop] Monitoring and manipulating brain function in non-human primates2018

    • Related Report
      2018 Annual Research Report

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Published: 2015-07-02   Modified: 2022-11-04  

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