| Budget Amount *help |
¥167,310,000 (Direct Cost: ¥128,700,000、Indirect Cost: ¥38,610,000)
Fiscal Year 2019: ¥29,640,000 (Direct Cost: ¥22,800,000、Indirect Cost: ¥6,840,000)
Fiscal Year 2018: ¥30,160,000 (Direct Cost: ¥23,200,000、Indirect Cost: ¥6,960,000)
Fiscal Year 2017: ¥29,250,000 (Direct Cost: ¥22,500,000、Indirect Cost: ¥6,750,000)
Fiscal Year 2016: ¥28,600,000 (Direct Cost: ¥22,000,000、Indirect Cost: ¥6,600,000)
Fiscal Year 2015: ¥49,660,000 (Direct Cost: ¥38,200,000、Indirect Cost: ¥11,460,000)
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| Outline of Final Research Achievements |
Thermal homeostasis, which is the nature to maintain internal body temperature within a narrow range, is particularly essential for homeothermic animals including humans, because all biological reactions and functions are affected by temperature. This study was performed to elucidate the neural circuit mechanisms underlying autonomic and behavioral controls of body temperature and metabolism. Specifically, we succeeded in the discoveries of the central ascending neural pathways that transmit thermosensory information for behavioral thermoregulation, the central circuit mechanism that drives hunger responses, and the central psychosomatic mechanism that connects the brain circuits processing psychological stress and emotion with those controlling vital functions. These circuit mechanisms we discovered not only underlie thermal homeostasis, but also function for the defence of life from a variety of environmental stressors.
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