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Development of comprehensive membrane voltage imaging techniques to elucidate the neuronal basis for the emergence of " individuality"

Planned Research

Project AreaIntegrative research toward elucidation of generative brain systems for individuality
Project/Area Number 16H06532
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionTokushima Bunri University

Principal Investigator

Tominaga Takashi  徳島文理大学, 神経科学研究所, 教授 (20344046)

Co-Investigator(Kenkyū-buntansha) 種村 健太郎  東北大学, 農学研究科, 教授 (20332322)
梶原 利一  明治大学, 理工学部, 専任准教授 (60356772)
高島 一郎  国立研究開発法人産業技術総合研究所, 情報・人間工学領域, 上級主任研究員 (90357351)
Project Period (FY) 2016-06-30 – 2021-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥107,640,000 (Direct Cost: ¥82,800,000、Indirect Cost: ¥24,840,000)
Fiscal Year 2020: ¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2019: ¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2018: ¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2017: ¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2016: ¥34,840,000 (Direct Cost: ¥26,800,000、Indirect Cost: ¥8,040,000)
Keywords脳機能イメージング / 膜電位感受性色素 / VSDイメージング / 脳回路可視化 / 行動プロファイリング / E/Iバランス / 行動様式変容モデル / 光計測 / 行動多様性プロファイリング / 神経回路可視化解析 / バルプロ酸 / 海馬 / 嗅内野 / 嗅周囲皮質 / 前帯状皮質 / 光信号 / 行動多様性プロファイリン グ / ビスフェノール / 個性 / イメージング / 神経回路
Outline of Final Research Achievements

The purpose of this study is to understand the emergent mechanism of "individuality" that guarantees the diversity of human behavior. In this project, we aim to develop measurement and evaluation techniques for brain circuit functions using experimental animals (mice and rats). The emergence of "individuality" depends on the function of large-scale, complex neural circuits consisting of many neurons and glial cells. To date, measurement methods of such neural circuit function is limited. In addition, the differences in the neural circuit functions responsible for the "individuality" are too small to detect and are easily hidden in the variability. Here, we have created a measurement technique using membrane voltage measurement with voltage-sensitive dyes to precisely capture the dynamics of large-scale neural circuit function.

Academic Significance and Societal Importance of the Research Achievements

社会がさまざまな価値を生み出す力は、社会を作る多様な「個性」に依存する。それを創発(生み出す)するメカニズムを知ることは、根本的に重要である。脳が「個性」を生み出す仕組みはまだほとんど知られていない。これは測る方法がないためである。今回、脳の働きに一番重要な神経細胞の膜電位を多数の細胞から同時に正確に読み出す技術が開発できた。これにより「個性」を生み出すメカニズムを調べることができるようになった。

Report

(6 results)
  • 2021 Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (123 results)

All 2022 2021 2020 2019 2018 2017 2016 Other

All Int'l Joint Research (10 results) Journal Article (34 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 34 results,  Open Access: 24 results) Presentation (73 results) (of which Int'l Joint Research: 24 results,  Invited: 19 results) Book (1 results) Remarks (5 results)

  • [Int'l Joint Research] Imperial Colledge London(英国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Woods Hole Marine Biological Laboratory(米国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Mount Sainai Hospital(カナダ)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Woods Hole Marine Biological Laboratory(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Mount Sainai Hospital(カナダ)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Marine Biological Laboratory, U Chicago(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Imperial College London(英国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Marine Biological Laboratory(米国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Mount Cinai Hospital(Canada)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] Woods Hole MBL(米国)

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Regulation Mechanism of Escape Response to Mechanical Stimulation in Paramecium2022

    • Author(s)
      掘学,石田正樹,冨永貴志
    • Journal Title

      Seibutsu Butsuri

      Volume: 62 Issue: 2 Pages: 114-115

    • DOI

      10.2142/biophys.62.114

    • ISSN
      0582-4052, 1347-4219
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Membrane Potential Imaging with Voltage-sensitive Dye (VSD) for Long-term Recording2021

    • Author(s)
      TOMINAGA Takashi、KAJIWARA Riichi、TOMINAGA Yoko
    • Journal Title

      Seibutsu Butsuri

      Volume: 61 Issue: 6 Pages: 404-408

    • DOI

      10.2142/biophys.61.404

    • NAID

      130008120222

    • ISSN
      0582-4052, 1347-4219
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Functional Aqp1 Gene Product Localizes on The Contractile Vacuole Complex in Paramecium multimicronucleatum2021

    • Author(s)
      Masaki Ishida, Manabu Hori, Yui Ooba, Masako Kinoshita, Tsuyoshi Matsutani, Musumi Naito, Taeko Hagimoto, Kuniko Miyazaki, Sou Ueda, Ken Miura, Takashi Tominaga
    • Journal Title

      Journal of Eukaryotic Microbiology

      Volume: - Issue: 3 Pages: 1-11

    • DOI

      10.1111/jeu.12843

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Perirhinal cortex area 35 controls the functional link between the perirhinal and entorhinal‐hippocampal circuitry.2021

    • Author(s)
      Kajiwara R, Tominaga T
    • Journal Title

      Bioessays

      Volume: 43 Issue: 3 Pages: 2000084-2000084

    • DOI

      10.1002/bies.202000084

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Structural Plastic Changes of Cortical Gray Matter Revealed by Voxel-Based Morphometry and Histological Analyses in a Monkey Model of Central Post-Stroke Pain2021

    • Author(s)
      Nagasaka Kazuaki、Nemoto Kiyotaka、Takashima Ichiro、Bando Daigo、Matsuda Keiji、Higo Noriyuki
    • Journal Title

      Cerebral Cortex

      Volume: 31 Issue: 10 Pages: 4439-4449

    • DOI

      10.1093/cercor/bhab098

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Behavioural effects in mice orally exposed to domoic acid or ibotenic acid are influenced by developmental stages and sex differences2021

    • Author(s)
      Sasaki T, Saito H, Hiradate Y, Hara K, *Tanemura K
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 558 Pages: 175-182

    • DOI

      10.1016/j.bbrc.2021.04.080

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Development of a new <i>in vitro</i> assay system for evaluating the effects of chemicals on DNA methylation2021

    • Author(s)
      Ideta-Otsuka Maky、Miyai Misato、Yamamoto Naoki、Tsuchimoto Ayaka、Tamura Hideki、Tanemura Kentaro、Shibutani Makoto、Igarashi Katsuhide
    • Journal Title

      The Journal of Toxicological Sciences

      Volume: 46 Issue: 2 Pages: 83-90

    • DOI

      10.2131/jts.46.83

    • NAID

      130007980526

    • ISSN
      0388-1350, 1880-3989
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Expression and Possible Role of Nicotinic Acetylcholine Receptor ε Subunit (AChRe) in Mouse Sperm2021

    • Author(s)
      Makino Y, Hiradate Y, Umezu K, Hara K, *Tanemura K
    • Journal Title

      Biology

      Volume: 10(1) Issue: 1 Pages: 46-46

    • DOI

      10.3390/biology10010046

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Expression and localization of alpha-tubulin N-acetyltransferase 1 in the reproductive system of male mice2021

    • Author(s)
      Yanai R, Yamashita Y, Umezu K, Hiradate Y, Hara K, Tanemura K.
    • Journal Title

      Journal of Reproduction and Development

      Volume: 67 Issue: 1 Pages: 59-66

    • DOI

      10.1262/jrd.2020-110

    • NAID

      130007986237

    • ISSN
      0916-8818, 1348-4400
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Lesions of the nucleus basalis magnocellularis (Meynert) induce enhanced somatosensory responses and tactile hypersensitivity in rats2021

    • Author(s)
      Dezawa Shinnosuke、Nagasaka Kazuaki、Watanabe Yumiko、Takashima Ichiro
    • Journal Title

      Experimental Neurology

      Volume: 335 Pages: 113493-113493

    • DOI

      10.1016/j.expneurol.2020.113493

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cortical direct current stimulation improves signal transmission between the motor cortices of rats2021

    • Author(s)
      Kunori Nobuo、Takashima Ichiro
    • Journal Title

      Neuroscience Letters

      Volume: 741 Pages: 135492-135492

    • DOI

      10.1016/j.neulet.2020.135492

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Roles of Adenylate Cyclases in Ciliary Responses of Paramecium to Mechanical Stimulation2020

    • Author(s)
      Mutsumi Kawano, Takashi Tominaga, Masaki Ishida, Manabu Hori
    • Journal Title

      Journal of Eukaryotic Microbiology

      Volume: 67 Issue: 5 Pages: 532-540

    • DOI

      10.1111/jeu.12800

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility.2020

    • Author(s)
      Hayase Y, Amano S, Hashizume K, Tominaga T, Miyamoto H, Kanno Y, Ueno-Inoue Y, Inoue T, Yamada M, Ogata S, Balan S, Hayashi K, Miura Y, Tokudome K, Ohno Y, Nishijo T, Momiyama T, Yanagawa Y, Takizawa A, Mashimo T, Serikawa T, Sekine A, Nakagawa E, Takeshita E, Yoshikawa T, Waga C, Inoue K, Goto YI, Nabeshima Y, et al.
    • Journal Title

      Acta Neuropathol Commun.

      Volume: 8 Issue: 1 Pages: 206-206

    • DOI

      10.1186/s40478-020-01082-6

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Optogenetic Manipulation of Postsynaptic cAMP Using a Novel Transgenic Mouse Line Enables Synaptic Plasticity and Enhances Depolarization Following Tetanic Stimulation in the Hippocampal Dentate Gyrus2020

    • Author(s)
      Luyben, T., Rai, J., Li, H., Georgiou, J., Avila, A., Zhen, M., Collingridge, G., Tominaga, T., Okamoto, K.
    • Journal Title

      Frontiers in Neural Circuits

      Volume: 14 Pages: 24-24

    • DOI

      10.3389/fncir.2020.00024

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Birefringence Changes of Dendrites in Mouse Hippocampal Slices Revealed with Polarizing Microscopy.2020

    • Author(s)
      Maki Koike-Tani M, Takashi Tominaga, Rudolf Oldenbourg, Tomomi Tani.
    • Journal Title

      Biophys J.

      Volume: - Issue: 10 Pages: 2366-2384

    • DOI

      10.1016/j.bpj.2020.03.016

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Time- and area-dependent macrophage/microglial responses after focal infarction of the macaque internal capsule2020

    • Author(s)
      Kato Junpei、Murata Yumi、Takashima Ichiro、Higo Noriyuki
    • Journal Title

      Neuroscience Research

      Volume: - Pages: 350-359

    • DOI

      10.1016/j.neures.2020.12.001

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of vitamin E deficiency on spermatogenesis in mice and its similarity to aging2020

    • Author(s)
      Hirokatsu Saito, Kenshiro Hara, Satoshi Kitajima, Kentaro Tanemura
    • Journal Title

      Reproductive Toxicology

      Volume: 98 Pages: 225-232

    • DOI

      10.1016/j.reprotox.2020.10.003

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Characteristics and Possible Role of Bovine Sperm Head-to-Head Agglutination2020

    • Author(s)
      Kohei Umezu, Shouhei Kurata, Hironori Takamori, Takashi Numabe, Yuuki Hiradate, Kenshiro Hara, Kentaro Tanemura
    • Journal Title

      Cells

      Volume: 9(8) Issue: 8 Pages: 1865-1865

    • DOI

      10.3390/cells9081865

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of neurotensin on cultured mouse preimplantation embryos2020

    • Author(s)
      Hiradate Y, Hara K, Tanemura K.
    • Journal Title

      Journal of Reproduction and Development

      Volume: 66 Issue: 5 Pages: 421-425

    • DOI

      10.1262/jrd.2020-002

    • NAID

      130007925623

    • ISSN
      0916-8818, 1348-4400
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Stromal cell-derived factor 1 regulates in vitro sperm migration towards the cumulus-oocyte complex in cattle2020

    • Author(s)
      Umezu K, Hara K, Hiradate Y, Numabe T, Tanemura K
    • Journal Title

      PLoS One

      Volume: 15 Issue: 4 Pages: e0232536-e0232536

    • DOI

      10.1371/journal.pone.0232536

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Suppression of mosaic mutation by co-delivery of CRISPR associated protein 9 and three-prime repair exonuclease 2 into porcine zygotes via electroporation2020

    • Author(s)
      Shiro YAMASHITA, Yuhei KOGASAKA, Yuuki HIRADATE, Kentaro TANEMURA, Yutaka SENDAI
    • Journal Title

      Journal of Reproduction and Development

      Volume: 66 Issue: 1 Pages: 41-48

    • DOI

      10.1262/jrd.2019-088

    • NAID

      130007798071

    • ISSN
      0916-8818, 1348-4400
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Brain Temperature Alters Contributions of Excitatory and Inhibitory Inputs to Evoked Field Potentials in the Rat Frontal Cortex2020

    • Author(s)
      Mizuho Gotoh, Kazuaki Nagasaka, Mariko Nakata, Ichiro Takashima, Shinya Yamamoto
    • Journal Title

      Frontiers in Cellular Neuroscience

      Volume: 14 Pages: 593027-593027

    • DOI

      10.3389/fncel.2020.593027

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Brain activity changes in a monkey model of central post-stroke pain2020

    • Author(s)
      Kazuaki Nagasaka, Ichiro Takashima, Keiji Matsuda, Noriyuki Higo
    • Journal Title

      Experimental Neurology

      Volume: 323 Pages: 113096-113096

    • DOI

      10.1016/j.expneurol.2019.113096

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cutting-edge brain research from a biophysical perspective: symposium synopsis of Session 1SCP at BSJ2019 in Miyazaki, Kyushu2020

    • Author(s)
      Tominaga, T., Kuhn, B
    • Journal Title

      Biophysical Reviews

      Volume: - Issue: 2 Pages: 261-262

    • DOI

      10.1007/s12551-020-00637-0

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Early‐life exposure to low levels of permethrin exerts impairments in learning and memory with the effects on neuronal and glial population in adult male mice2019

    • Author(s)
      Saito Hirokatsu、Hara Kenshiro、Tominaga Takashi、Nakashima Kinichi、Tanemura Kentaro
    • Journal Title

      Journal of Applied Toxicology

      Volume: 39 Issue: 12 Pages: 1651-1662

    • DOI

      10.1002/jat.3882

    • NAID

      130007898356

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Wide-field Single-photon Optical Recording in Brain Slices Using Voltage-sensitive Dye2019

    • Author(s)
      Tominaga Yoko、Taketoshi Makiko、Maeda Naoko、Tominaga Takashi
    • Journal Title

      Journal of Visualized Experiments

      Volume: - Issue: 148

    • DOI

      10.3791/59692

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Differences in resistance against osmotic challenge among C57BL/6, DBA/2 and their hybrid mice metaphase II (MII) stage oocytes2019

    • Author(s)
      Goto Mei、Saito Hirokatsu、Hiradate Yuki、Hara Kenshiro、Tanemura Kentaro
    • Journal Title

      Zygote

      Volume: 27 Issue: 4 Pages: 250-254

    • DOI

      10.1017/s0967199418000370

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Capacitation of mouse sperm is modulated by gamma-aminobutyric acid (GABA) concentration2019

    • Author(s)
      KURATA Shouhei、HIRADATE Yuuki、UMEZU Kohei、HARA Kenshiro、TANEMURA Kentaro
    • Journal Title

      Journal of Reproduction and Development

      Volume: 65 Issue: 4 Pages: 327-334

    • DOI

      10.1262/jrd.2019-008

    • NAID

      130007689005

    • ISSN
      0916-8818, 1348-4400
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Evaluation of acute anodal direct current stimulation-induced effects on somatosensory-evoked responses in the rat2019

    • Author(s)
      Kunori Nobuo、Takashima Ichiro
    • Journal Title

      Brain Research

      Volume: 1720 Pages: 146318-146318

    • DOI

      10.1016/j.brainres.2019.146318

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of GABAergic transmission in the nucleus accumbens related to cue-selection behavior with a waiting period.2019

    • Author(s)
      Okubo M, Matsuzaki K, Okada N, Komura Y, Kajiwara R.
    • Journal Title

      Proc of Life Eng Symp 2019

      Volume: - Pages: 75-79

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Time-lapse optical imaging system for monitoring the resting membrane potential change of neurons in a mouse brain slice.2019

    • Author(s)
      Machida Y, Yamada Y, Mizunuma S, Tominaga T, Kajiwara R
    • Journal Title

      Proc of Life Eng Symp 2019

      Volume: - Pages: 139-142

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Network Plasticity Involved in the Spread of Neural Activity Within the Rhinal Cortices as Revealed by Voltage-Sensitive Dye Imaging in Mouse Brain Slices2019

    • Author(s)
      Kajiwara Riichi、Tominaga Yoko、Tominaga Takashi
    • Journal Title

      Frontiers in Cellular Neuroscience

      Volume: 13 Pages: 1-12

    • DOI

      10.3389/fncel.2019.00020

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Overall Assay of Neuronal Signal Propagation Pattern With Long-Term Potentiation (LTP) in Hippocampal Slices From the CA1 Area With Fast Voltage-Sensitive Dye Imaging2018

    • Author(s)
      Tominaga Yoko、Taketoshi Makiko、Tominaga Takashi
    • Journal Title

      Frontiers in Cellular Neuroscience

      Volume: 12 Pages: 1-13

    • DOI

      10.3389/fncel.2018.00389

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Interplay between non-NMDA and NMDA receptor activation during oscillatory wave propagation: Analyses of caffeine-induced oscillations in the visual cortex of rats2016

    • Author(s)
      Hiroshi Yoshimuraa, b, , , Tokio Sugaib, Nobuo Katob, Takashi Tominagac, Yoko Tominagac, Takahiro Hasegawaa, Chenjuan Yaoa, Tetsuya Akamatsua
    • Journal Title

      Neural Networks

      Volume: 0 Pages: 0-0

    • DOI

      10.1016/j.neunet.2016.03.012

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Presentation] Quantitative detection of the effect on neuronal responses in tri-synapses with the acute application of bisphenol-A-related substances on hippocampal slices with voltage-sensitive dye (VSD)2021

    • Author(s)
      Y. TOMINAGA, M. TAKETOSHI, K. TANEMURA, *T. TOMINAGA
    • Organizer
      Society for Neuroscience, Neuroscience 2021
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] In vitro assay for seizure liability using voltage-sensitive dye imaging (VSDI) in the mouse hippocampus2021

    • Author(s)
      Y. UTSUMI, M. TAKETOSHI, N. OHARA, M. MIWA, Y. TOMINAGA, T. TOMINAGA,
    • Organizer
      Society for Neuroscience, Neuroscience 2021
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Membrane voltage imaging: Bird’s-eye survey of the brain activity in one-time events when individuality emerges2021

    • Author(s)
      T Tominaga
    • Organizer
      The 80th Fujihara Seminar
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] A novel in vitro assay for seizure prediction using voltage-sensitive dye imaging (VSDI) in the mouse hippocampus2021

    • Author(s)
      Yuichi Utsumi, Makiko Taketoshi, Nana Ohara, Michiko Miwa, Yoko Tominaga and Takashi Tominaga
    • Organizer
      The 80th Fujihara Seminar
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Acute neuroinflammation induced by short-term treatment with Cuprizone leads to behavioral disorders similar to schizophrenia2021

    • Author(s)
      Kyoka Tsukuda, Takashi Kubota, Aoi Chiba, Takashi Tominaga, Yasushi Kishimoto & Kentaro Nakashima
    • Organizer
      The 80th Fujihara Seminar
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Transgenerational epigenetic effects of testicular histone hyperacetylation in mice2021

    • Author(s)
      Kazuya Sakai, Takashi Tominaga, Kenshiro Hara, and Kentaro Tanemura
    • Organizer
      The 80th Fujihara Seminar
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] マウス前頭前野の同側,反対側への神経活動伝播の膜電位感受性色素による機能的解剖2021

    • Author(s)
      冨永 貴志、グサイン プージャ、竹歳 麻紀子、冨永 洋子
    • Organizer
      第44回日本神経科学大会CJK第1回国際大会
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 膜電位感受性色素( VSD)イメージングによる in vitro痙攣リスク予測2021

    • Author(s)
      内海 雄一、竹歳 麻紀子、小原 菜夏、三輪 倫子、冨永 洋子、冨永 貴志
    • Organizer
      第44回日本神経科学大会CJK第1回国際大会
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cuprizone短期投与による脳内炎症モデルマウスは統合失調症様行動障害を示す2021

    • Author(s)
      佃 京華、窪田 剛志、千葉 葵、冨永 貴志、岸本 泰司、中島 健太郎
    • Organizer
      第44回日本神経科学大会CJK第1回国際大会
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 抑制性シナプス抑制因子MDGA1のヘミ欠損は海馬 LTPの低下と学習・記憶異常を引き起こすが、サイクロセリンの急性投与により回復する2021

    • Author(s)
      山本 融、尾嶋 大喜、多田 篤史、田之上 優、黒川 直弘、窪田 剛志、高橋 弘雄、岸本 泰司、冨永 貴志
    • Organizer
      第44回日本神経科学大会CJK第1回国際大会
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 電位感受性色素(VSD)による全神経回路活動計測の開発:海馬スライス標本へのビスフェノールA関連物質の急性投与2021

    • Author(s)
      冨永 貴志, 竹歳 麻紀子, 種村 健太郎, 冨永 洋子
    • Organizer
      第48回日本毒性学会学術年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 電位感受性色素(VSD)イメージングによるinvitro痙攣リスク評価法の開発2021

    • Author(s)
      内海 雄一, 竹歳 麻紀子, 小原 菜夏, 三輪 倫子, 冨永 洋子, 冨永 貴志
    • Organizer
      第48回日本毒性学会学術年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] A mouse model of neuroinflammation induced by short-term exposure to Cuprizone show behavioral symptoms similar to schizophrenia Cuprizone 短期投与脳内炎症モデルマウスは統合失調症様精神行動障害を示す2021

    • Author(s)
      佃 京華, 窪田剛志, 千葉 葵, 冨永 貴志, 岸本 泰司, 中島 健太郎
    • Organizer
      日本生物物理学会 中国四国支部大会(第12回)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 膜電位感受性色素(VSD)イメージングによる in vitro 痙攣リスクアッセイ法による周産期バルプロ酸投与動物でのリスク評価の試み2021

    • Author(s)
      小原菜夏,内海雄一,竹歳麻紀子,三輪倫子,佃京華 冨永洋子,中島健太郎, 冨永貴志
    • Organizer
      日本生物物理学会 中国四国支部大会(第12回)
    • Related Report
      2020 Annual Research Report
  • [Presentation] Optical membrane potential recordings with voltage-sensitive dye (VSD) enabling recordings of rare and unique neuronal activity patterns2020

    • Author(s)
      Y Tominaga, R Kajiwara, T Tominaga
    • Organizer
      Society for Neuroscience, Global Connectome (Online)
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Imaging analysis of the long-term potentiation of the mouse hippocampal activityマウス海馬の長期増強を膜電位感受色素によるイメージングで観察する2020

    • Author(s)
      冨永 洋子, 竹歳 麻紀子, 冨永 貴志
    • Organizer
      第58回日本生物物理学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 発達期および成体期におけるマウス嗅皮質神経回路の膜電位イメージング解析2020

    • Author(s)
      待田 燿子 , 山田 悠太 , 冨永 貴志 , 梶原 利一
    • Organizer
      第43回日本神経科学大会(
    • Related Report
      2020 Annual Research Report
  • [Presentation] 単回頻回の膜電位感受性色素( VSD)による広視野可視化法 は神経回路の特異な活動や振動現象の発見に役立つ2020

    • Author(s)
      冨永 貴志、梶原 利一、冨永 洋子
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] VSDイメージングによる神経回路毒性の網羅的評価2020

    • Author(s)
      冨永 貴志, 冨永 洋子
    • Organizer
      第47回日本毒性学会学術年会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] A fast intrinsic optical signal (fios) from unstained hippocampal slice is a novel kind of optical signal: comparison with the voltage-sensitive dye signal2019

    • Author(s)
      Yoko TOMINAGA, Maki KOIKE-TANI, Tomomi TANI, Takashi TOMINAGA
    • Organizer
      Neuroscience Meeting Planner. Chicago, Society for Neuroscience 20191019 Chicago McCormic Place
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Optical Recording Methods with Voltage-Sensitive Dye (VSD) Is Useful to Evaluate the Impact of Chemicals on Brain Activities in Acute and Late Effects.2019

    • Author(s)
      Yoko Tominaga, Makiko Taketoshi, Kentaro Tanemura, Takashi Tominaga
    • Organizer
      IUTOX 15th International Congress of Toxicology
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Early-Life Exposure to Low Levels of Permethrin Exerts Impairments in Learning and Memory Associated with Glial Cell Disturbance in Adult Male Mice.2019

    • Author(s)
      Hirokatsu Saito, Kenshiro Hara, Takashi Tominaga, Kinichi Nakashima, Kentaro Tanemura
    • Organizer
      IUTOX 15th International Congress of Toxicology
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Time-lapse optical imaging system for monitoring the resting membrane potential change of neurons in a mouse brain slice.2019

    • Author(s)
      Machida Y, Yamada Y, Mizunuma S, Tominaga T, Kajiwara R
    • Organizer
      Proc of Life Eng Symp 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 光信号で「見る」神経回路のはたらき-膜電位感受性色素(VSD)を中心に」シンポジウム 1SCP 生物物理で見る脳神経回路 (オーガナイザー:冨永貴志、Bernd Kuhn)2019

    • Author(s)
      冨永 貴志, 冨永 洋子
    • Organizer
      第57回日本生物物理学会年会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 神経回路ダイナミクスのリアルタイム光学計測:膜電位感受性色素(VSD)と早い内因性信号(FIOS)2019

    • Author(s)
      冨永貴志,冨永洋子
    • Organizer
      第42回日本神経科学大会 第62回日本神経化学大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] マウス海馬長期増強(LTP)の光学測定2019

    • Author(s)
      冨永 洋子, 竹歳 麻紀子, 冨永 貴志
    • Organizer
      第42回日本神経科学大会 第62回日本神経化学大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] シナプス形成抑制因子MDGAファミリー分子群の欠失が引き起こすE/Iバランス偏移がもたらす認知・行動異常2019

    • Author(s)
      山本 融, 尾嶋 大喜. Hossain MD Razib,多田 篤史,黒川 直弘 ,長澤 研,琢磨 和晃 ,中井 雄規 ,高橋 弘雄 ,冨永 貴志 ,岸本 泰司
    • Organizer
      第42回日本神経科学大会 第62回日本神経化学大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 嗅周囲皮質/嗅内皮質ネットワーク可塑性への遅延性不活性化カリウム電流の関与:マウス脳スライスの膜電位イメージング2019

    • Author(s)
      梶原 利一 / Riichi Kajiwara:1 冨永 洋子 / Yoko Tominaga:2 冨永 貴志 / Takashi Tominaga:2
    • Organizer
      第42回日本神経科学大会 第62回日本神経化学大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 低用量化学物質ばく露が誘発する脳回路機能変調を検出する膜電位イメージング解析2019

    • Author(s)
      冨永貴志
    • Organizer
      第46回日本毒性学会学術年会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 胎児期バルプロ酸曝露のミクログリア活性と神経回路機能に及ぼす影響2019

    • Author(s)
      石原 康宏1, 本田 達也1, 冨永 貴志2, 伊藤 康一3, 山﨑 岳
    • Organizer
      第46回日本毒性学会学術年会
    • Related Report
      2019 Annual Research Report
  • [Presentation] バルプロ酸とミノサイクリンの周産期投与による遅発性の海馬回路機能変化の 膜電位感受性色素による可視化解析2019

    • Author(s)
      高橋和可子, 竹歳麻紀子, 冨永洋子, 石原康宏 ,冨永貴志
    • Organizer
      11 回日本生物物理学会 中国四国支部大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 海馬神経回路の興奮/抑制(E/I)バランスを欠く MDGA1 欠損マウスにおけ る歯状回長期増強への影響2019

    • Author(s)
      中井雄規,尾嶋大喜,山本融,冨永貴志
    • Organizer
      11 回日本生物物理学会 中国四国支部大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Theta phase-dependent competitive long-term potentiation in area CA1 of the hippocampal slices caused by feed- forward and feedback gabaergic control2018

    • Author(s)
      T Tominaga, Y Tominaga
    • Organizer
      Society for Neuroscience, SanDiego
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Voltage-sensitive dye imaging: practical application to evaluate hippocampal and related cortical activities in health and disease2018

    • Author(s)
      Takashi Tominaga
    • Organizer
      OIST Mini Symposium
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Voltage-sensitive dye imaging of the brain slice preparation - the hippocampus and the related cortexes.2018

    • Author(s)
      Takashi Tominaga
    • Organizer
      Merocyanine 540 45+1 MBL
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 「膜電位感受性色素を用いた脳神経回路活動の定量解析:海馬と関連領域の例から」2018

    • Author(s)
      冨永貴志
    • Organizer
      第三回 新学術領域「個性創発脳」若手研究者の会・技術支援講習会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] The paired burst facilitation (PBF) of the hippocampus employ the distinct feedforward- and feedback- GABAergic controls in the circuit 海馬CA1でペアドバースト促通(PBF)はフィードバックとフィードフォワードの異なるGABA作動性制御を使う2018

    • Author(s)
      冨永貴志,冨永洋子
    • Organizer
      日本生物物理学会第56回年会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Voltage-sensitive dye imaging of the interhemispheric neural activity across the anterior cingulate cortex (ACC) via corpus callosum2018

    • Author(s)
      Gusain Pooja, Taketoshi Makiko, Tominaga Yoko, Tominaga Takashi
    • Organizer
      日本生物物理学会第56回年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Molecular mechanism of escape response induced by mechanical stimulation in Paramecium 機械刺激がゾウリムシの逃走反応を誘導するしくみ2018

    • Author(s)
      河野 睦, 世戸 彩華, 冨永 貴志, 石田 正樹, 堀 学
    • Organizer
      日本生物物理学会第56回年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] A view with voltage-sensitive-dye onto the function of the hippocampal neural circuit 膜電位感受性色素(VSD)で測る海馬神経回路のはたらき2018

    • Author(s)
      Takashi Tominaga, Yoko Tominaga
    • Organizer
      計測自動制御学会 ライフエンジニアリング部門シンポジウム2018
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 海馬CA1野でシーターバースト刺激はフィードバック,フィードフォワードGABA調節を使って位相依存的なLTPを起こす Feedforward- and feedback-GABAergic control of the theta burst stimulation (TBS) induce phase-dependent selective long-term potentiation in area CA1 of the hippocampus.2018

    • Author(s)
      冨永 貴志, 冨永 洋子
    • Organizer
      第41回日本神経科学大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] マウス海馬CA1野における新規の早い内因性光学計測:膜電位感受性信号との比較 Novel fast intrinsic optical signal related to the membrane potential change in the area CA1 of hippocampal slices in mice: comparison to the voltage-sensitive dye signal2018

    • Author(s)
      冨永洋子,谷ー小池 真紀,谷知巳,冨永貴志
    • Organizer
      第41回日本神経科学大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] マウス脳スライス上のVSD信号を用いた嗅周囲皮質の局所的なGABA作動性抑制系システムの解析 Analysis of Local GABAergic inhibitory system in Perihinal Cortex Using Voltage-Sensitive Dye Signal in Mice brain Slices2018

    • Author(s)
      和歌山ゆうか,山田悠太,冨永貴志,冨永洋子,梶原利一
    • Organizer
      第41回日本神経科学大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Analysis of functional connectivity of mice brain by real-time optical recording2018

    • Author(s)
      Pooja Gusain, Makiko Taketoshi, Yoko Tominaga, Naoko Maeda, Takashi Tominaga
    • Organizer
      第41回日本神経科学大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 膜電位感受性色素による脳神経回路イメージング Imaging of neuronal circuit activity with voltage-sensitive dye - stability matters2018

    • Author(s)
      冨永貴志,種村健太郎
    • Organizer
      新学術領域研究「個性」創発脳 第3回領域会議
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 子どもへの低用量化学物質暴露が誘発する脳回路機能異常のイメージング解析」シンポジウム「子どもへの低用量化学物質暴露が誘発する情動認知行動影響とその評価系の開発 Development of evaluation methods on emotional and cognitive behavioral toxicity induced by low-dosed chemical exposure at early life stage2018

    • Author(s)
      冨永 貴志, 冨永 洋子
    • Organizer
      第45回日本毒性学会学術年会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] ネオニコチノイド類の妊娠期投与が起こす遅発性脳機能異常の神経回路 機構解析2018

    • Author(s)
      常盤 果那 ,竹歳 麻紀子 ,冨永 洋子,冨永 貴志
    • Organizer
      日本生物物理学会第10回中四国支部大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 精子エピゲノム影響評価による非侵襲的な早期精巣毒性バイオマーカーの探索2018

    • Author(s)
      酒井和哉、大塚(出田)まき、斉藤洋克、平舘裕希、原健士朗、五十嵐勝秀、種村健太郎
    • Organizer
      第12回日本エピジェネティクス研究会年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Early life exposure to low levels of permethrin exerts slight impairment of central nervous system in male mice2018

    • Author(s)
      Hirokatsu Saito, Takashi Tominaga, Kenshiro Hara, Kentaro Tanemura
    • Organizer
      平成28年度採択新学術領域「個性」創発脳 第1回国際シンポジウム 「Toward Understanding “INDIVIDUALITY”」
    • Related Report
      2018 Annual Research Report
  • [Presentation] Chemical-induced epigenetic effects on mouse sperm using valproic acid2018

    • Author(s)
      Kazuya Sakai, Masafumi Sekine, Jin Hiura, Hiroaki Okae, Takashi Tominaga, Takahiro Arima, Kenshiro Hara, Kentaro Tanemura
    • Organizer
      平成28年度採択新学術領域「個性」創発脳 第1回国際シンポジウム 「Toward Understanding “INDIVIDUALITY”」
    • Related Report
      2018 Annual Research Report
  • [Presentation] Early-life exposure to low levels of permethrin exerts impairments in learning and memory associated with glial cell disturbance in adult male mice2018

    • Author(s)
      Hirokatsu Saito , Kenshiro Hara, Takashi Tominaga, Kinichi Nakashima, Kentaro Tanemura
    • Organizer
      次世代脳プロジェクト 冬のシンポジウム
    • Related Report
      2018 Annual Research Report
  • [Presentation] Paternal VPA-exposure affects the offspring’s behavior through sperm DNA methylation2018

    • Author(s)
      Kazuya Sakai, Masafumi Sekine, Jin Hiura, Hiroaki Okae, Takashi Tominaga, Takahiro Arima, Kenshiro Hara, Kentaro Tanemura
    • Organizer
      次世代脳プロジェクト 冬のシンポジウム
    • Related Report
      2018 Annual Research Report
  • [Presentation] マウス行動様式と海馬神経回路機能~系統間差と交雑影響~2018

    • Author(s)
      後藤萌、斉藤洋克、原唯香、冨永貴志、種村健太郎
    • Organizer
      次世代脳プロジェクト 冬のシンポジウム
    • Related Report
      2018 Annual Research Report
  • [Presentation] 膜電位感受性色素(VSD)を用いた光計測技術によるリプログラミングがん細胞膜電位計測法2018

    • Author(s)
      平島 寛司、冨永 貴志、冨永 洋子、岳 鳳鳴、滝澤 佐季子、横山 忠幸、松本 健、友常 大八郎、佐々木 克典
    • Organizer
      第17回日本再生医療学会総会,パシフィコ横浜
    • Related Report
      2017 Annual Research Report
  • [Presentation] Voltage-sensitive dye imaging study of the input-dependent GABAergic control of the paired burst facilitation (PBF) in area CA1 of the hippocampus2017

    • Author(s)
      Tominaga T and Tominaga Y.
    • Organizer
      Society for Neuroscience,Washington DC
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Voltage-sesitive dye signal analysis of inhibitory components in mouse perirhinal-entorrhinal cortical slices2017

    • Author(s)
      WAKAYAMA Y, KAMADA S, YAMADA Y, TOMINAGA T, KAJIWARA R
    • Organizer
      Society for Neuroscience,Washington DC
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 「イントロダクション」ワークショップ「個性」創発神経基盤の統合的理解に向けた階層横断的解析2017

    • Author(s)
      冨永貴志
    • Organizer
      生命科学系合同年次大会 ConBio2017 神戸ポートピアホテル
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 膜電位イメージングの技術支援:実施例から2017

    • Author(s)
      冨永貴志
    • Organizer
      新学術領域「個性」創発脳の第2回若手の会・技術講習会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 海馬CA1野のペアドバーストファシリテーション(PBF)のGABAergicなフィードフォワード,フィードバック調節:膜電位感受性色素による研究2017

    • Author(s)
      冨永貴志,冨永洋子
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] カフェイン投与により誘発されるラット視覚野オシレーションにおけるnon-NMDA受容体とNMDA受容体の相互交錯的関与2017

    • Author(s)
      吉村 弘,須貝 外喜夫,加藤 伸郎,冨永 貴志,冨永 洋子,長谷川 敬展,姚 陳娟,赤松 徹也
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 膜電位イメージングによる嗅周囲皮質の抑制性/興奮性神経活動の層分布解析2017

    • Author(s)
      和歌山 ゆうか,鎌田 翔仁,山田 悠太,冨永 貴志 ,梶原 利一
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 神経興奮伝播の促進に関与するマウス嗅皮質神経回路可塑性の膜電位イメージング2017

    • Author(s)
      梶原 利一,和歌山 ゆうか,冨永 洋子,冨永 貴志
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 情動認知行動影響の毒性評価における神経回路機能イメージング法を用いた神経基盤解析2017

    • Author(s)
      冨永貴志,冨永洋子
    • Organizer
      第44回日本毒性学会学術年会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 個性」創発の神経基盤解析のための神経回路イメージング法と行動様式プロファイリング2017

    • Author(s)
      冨永貴志
    • Organizer
      新学術領域「個性創発脳」第2回領域会議
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 膜電位感受性色素を使った光計測法により神経回路機構を探るー海馬を中心として2017

    • Author(s)
      冨永貴志,冨永洋子
    • Organizer
      第37回 Neuroscience Seminar Tokushima
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Activation of GABAA-receptors by high-frequency stimuli causes paired burst facilitations in area CA1 of the hippocampal slice2016

    • Author(s)
      Tominaga T and Tominaga Y.
    • Organizer
      Society for Neuroscience, 2016
    • Place of Presentation
      San Diego
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Imaging of polarized light signal changes associated with neuronal activity in mouse hippocampus2016

    • Author(s)
      M. Koike-Tani, S. Mehta, T. Tominaga, R. Oldenbourg, T. Tani
    • Organizer
      Society for Neuroscience, 2016
    • Place of Presentation
      San Diego
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Network plasticity facilitating the neural excitation propagation between the perirhinal and entorhinal cortices as revealed by voltage-sensitive dye imaging2016

    • Author(s)
      R. Kajiwara, Y. Wakayama, Y. Tominaga, T. Tominaga
    • Organizer
      Society for Neuroscience, 2016
    • Place of Presentation
      San Diego
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Rapid postsynaptic cAMP signaling regulates structural and functional potentiation underlying learning and memory2016

    • Author(s)
      T. Luyben, J. Borovac, M. Valencia, M. Khan, T. Tominaga, K. Okamoto
    • Organizer
      Society for Neuroscience, 2016
    • Place of Presentation
      San Diego
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 「使える」膜電位感受性色素による神経回路解析法 “Conventional”voltage sensitive dye imaging of neural circuit activity 公募シンポジウム「神経活動イメージングの最先端:新規ツールとその活用 (Advances in imaging neuronal activity: New tools and applications)オーガナイザー ベアン クン(沖縄科学技術大),冨永 貴志(徳島文理大)2016

    • Author(s)
      冨永 貴志, 冨永 洋子
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば国際会議場
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 新規偏光顕微鏡を用いたマウス海馬スライスにおけるシナプス活動の非侵襲的計測 Imaging of neuronal activity in mice hippocampal slices by instantaneous polarized light microscopy 公募シンポジウム「神経活動イメージングの最先端:新規ツールとその活用 (Advances in imaging neuronal activity: New tools and applications)オーガナイザー ベアン クン(沖縄科学技術大),冨永 貴志(徳島文理大)2016

    • Author(s)
      小池(谷) 真紀, Mehta Shalin, Oldenburg Rudolf, 冨永貴志, 谷 知己
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば国際会議場
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] GABA依存のペアードバースト促進は海馬CA1における新規のNMDA非依存的な短期可塑性であるGABA dependent paired burst facilitation (PBF) is a new class of NMDA-independent short- term plasticity in area CA1 of the hippocampal slice. A voltage-sensitive dye study2016

    • Author(s)
      冨永貴志 冨永洋子
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2016 Annual Research Report
  • [Presentation] ラット傍梨状核において大脳皮質脱抑制下で生じるエコー波 Cortical disinhibition-induced echo wave in the EPN of rat2016

    • Author(s)
      吉村弘,冨永洋子,冨永貴志
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2016 Annual Research Report
  • [Book] 個性を見る/個性創発の科学2021

    • Author(s)
      冨永貴志/保前文高・大隅典子編
    • Total Pages
      232
    • Publisher
      朝倉書店
    • ISBN
      9784254102956
    • Related Report
      2020 Annual Research Report
  • [Remarks] 徳島文理大学神経科学研究所Laboratory for Neural Circuit Systems

    • URL

      https://www.bunri-u.ac.jp/ins/lncs.html

    • Related Report
      2020 Annual Research Report
  • [Remarks] 徳島文理大学神経科学研究所

    • URL

      https://www.bunri-u.ac.jp/ins/

    • Related Report
      2020 Annual Research Report
  • [Remarks] 徳島文理大学神経科学研究所

    • URL

      http://kp.bunri-u.ac.jp/kph20/

    • Related Report
      2019 Annual Research Report 2017 Annual Research Report
  • [Remarks] JoveJounral

    • URL

      http://kp.bunri-u.ac.jp/kph20/jovemovie.html

    • Related Report
      2019 Annual Research Report
  • [Remarks] 冨永ラボ外部ページ

    • URL

      http://dev.main.jp/ttext/TText/TominagaLab.html

    • Related Report
      2017 Annual Research Report

URL: 

Published: 2016-07-04   Modified: 2023-01-30  

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