| Budget Amount *help |
¥162,240,000 (Direct Cost: ¥124,800,000、Indirect Cost: ¥37,440,000)
Fiscal Year 2021: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2020: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2019: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2018: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2017: ¥98,280,000 (Direct Cost: ¥75,600,000、Indirect Cost: ¥22,680,000)
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| Outline of Final Research Achievements |
We have been working on the development of next-generation metabolome analysis base technologies that enables quantitative metabolome analysis and contributes to metabolic adaptation analysis. We succeeded in developing a quantitative metabolome analysis system using various chromatography-mass spectrometry systems. We also developed a system for quantitative analysis of individual components by combining LC and various detectors. In addition, we developed stable isotope-labeled internal standards necessary for quantitative analysis in mass spectrometry, probes for highly sensitive quantitative analysis of trace components, and a data analysis system for quantitative metabolome analysis. We have established the basic technologies for quantitative metabolome analysis, and have conducted many applied studies of metabolic adaptation using these technologies with collaborators both inside and outside of the project.
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