| Budget Amount *help |
¥171,210,000 (Direct Cost: ¥131,700,000、Indirect Cost: ¥39,510,000)
Fiscal Year 2021: ¥29,250,000 (Direct Cost: ¥22,500,000、Indirect Cost: ¥6,750,000)
Fiscal Year 2020: ¥25,350,000 (Direct Cost: ¥19,500,000、Indirect Cost: ¥5,850,000)
Fiscal Year 2019: ¥20,410,000 (Direct Cost: ¥15,700,000、Indirect Cost: ¥4,710,000)
Fiscal Year 2018: ¥31,200,000 (Direct Cost: ¥24,000,000、Indirect Cost: ¥7,200,000)
Fiscal Year 2017: ¥65,000,000 (Direct Cost: ¥50,000,000、Indirect Cost: ¥15,000,000)
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| Outline of Final Research Achievements |
Catalytic reactions that convert stable and readily available organic molecules into key intermediates for pharmaceuticals and agrochemicals under mild conditions are expected to revolutionize synthetic processes in terms of reducing the number of steps and waste by-products. To realize such catalytic reactions, we proposed the concept of hybrid catalysis, which utilizes the function of multiple catalysts in a concerted and integrated manner. Based on this concept, we have found reactions that activate stable and readily available organic molecules such as simple alkenes, alcohols, and carboxylic acids, and transform them into useful chiral molecules via highly stereoselective carbon frame construction. We have also found reactions that convert alcohols to ketones while releasing molecular hydrogen.
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