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Mechanisms controlling the indeterminacy of plant stem cells

Planned Research

Project AreaPrinciples of pluripotent stem cells underlying plant vitality
Project/Area Number 17H06475
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionTohoku University

Principal Investigator

Kyozuka Junko  東北大学, 生命科学研究科, 教授 (90273838)

Co-Investigator(Kenkyū-buntansha) 豊岡 公徳  国立研究開発法人理化学研究所, 環境資源科学研究センター, 上級技師 (10360596)
Project Period (FY) 2017-06-30 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥140,920,000 (Direct Cost: ¥108,400,000、Indirect Cost: ¥32,520,000)
Fiscal Year 2021: ¥21,450,000 (Direct Cost: ¥16,500,000、Indirect Cost: ¥4,950,000)
Fiscal Year 2020: ¥22,360,000 (Direct Cost: ¥17,200,000、Indirect Cost: ¥5,160,000)
Fiscal Year 2019: ¥22,360,000 (Direct Cost: ¥17,200,000、Indirect Cost: ¥5,160,000)
Fiscal Year 2018: ¥21,450,000 (Direct Cost: ¥16,500,000、Indirect Cost: ¥4,950,000)
Fiscal Year 2017: ¥53,300,000 (Direct Cost: ¥41,000,000、Indirect Cost: ¥12,300,000)
Keywords植物幹細胞 / 無限成長性 / 有限成長性 / 転写因子APO2 / TAWAWA(TAW) / イネ穂 / ゼニゴケ / ヒメツリガネゴケ / 幹細胞の多能性 / イネAPO1/APO2 / TAWAWA1 / 頂端幹細胞 / 植物 / 幹細胞 / 多能性 / メリステム / 幹細胞の可視化 / イネ花序幹細胞 / APO1 / イネ / 1細胞トランスクリプトーム / 電子顕微鏡 / TAWWA1 / 花序幹細胞 / APO1、APO2 / 発生・分化 / 遺伝子
Outline of Final Research Achievements

The pattern of the inflorescence (the branch on which the flowers arrive) is an important trait that affects plant appearance and crop yield and is determined by the timing of the transition of the meristem phase from indeterminate inflorescence meristem to determinate floral meristems. The rice APO2 and TAW1 were known to be important transcription factors that control inflorescence patterns through the control of the meristem phase change. In this study, we show that APO2 binds to the regulatory regions of a common set of genes and repeatedly controls these genes to determine the inflorescence pattern. We also found that TAW1 directly controls genes essential for floral meristem specification and maintenance of stem cells. Furthermore, we discovered that TAW1 functions are widely conserved in land plants.

Academic Significance and Societal Importance of the Research Achievements

本研究で解析した遺伝子はイネ科植物の花序形成において主導的な役割を果たす遺伝子であり、それらの機能や進化に関して基本的な知見が得られた。本成果は基礎研究という立場から重要であり、また、作物の育種という観点からも意義深い。

Report

(6 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (24 results)

All 2022 2021 2020 2019 2017 Other

All Int'l Joint Research (1 results) Journal Article (11 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 11 results,  Open Access: 3 results) Presentation (10 results) (of which Int'l Joint Research: 5 results,  Invited: 4 results) Funded Workshop (2 results)

  • [Int'l Joint Research] 南京農業大学(中国)

    • Related Report
      2021 Annual Research Report
  • [Journal Article] Origins and evolution of the dual functions of strigolactones as rhizosphere signaling molecules and plant hormones2022

    • Author(s)
      Kyozuka Junko、Nomura Takahito、Shimamura Masaki
    • Journal Title

      Current Opinion in Plant Biology

      Volume: 65 Pages: 102154-102154

    • DOI

      10.1016/j.pbi.2021.102154

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The bryophytes Physcomitrium patens and Marchantia polymorpha as model systems for studying evolutionary cell and developmental biology in plants.2022

    • Author(s)
      Naramoto, S., Hata, Y., Fujita T, and Kyozuka J.
    • Journal Title

      The Plant Cell

      Volume: 34 Issue: 1 Pages: 228-246

    • DOI

      10.1093/plcell/koab218

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ABERRANT PANICLE ORGANIZATION2 controls multiple steps in panicle formation through common direct target genes.2022

    • Author(s)
      Miao Y, Xun Q, Taji T, Tanaka K, Yasuno N, Ding C, Kyozuka J.
    • Journal Title

      Plant Physiology

      Volume: 未定

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] NARROW AND DWARF LEAF 1, the Ortholog of Arabidopsis ENHANCER OF SHOOT REGENERATION1/DORNROSCHEN, Mediates Leaf Development and Maintenance of the Shoot Apical Meristem in Oryza sativa L2021

    • Author(s)
      Kusnandar Andree S、Itoh Jun-Ichi、Sato Yutaka、Honda Eriko、Hibara Ken-ichiro、Kyozuka Junko、Naramoto Satoshi
    • Journal Title

      Plant and Cell Physiology

      Volume: 63 Issue: 2 Pages: 265-278

    • DOI

      10.1093/pcp/pcab169

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fundamental mechanisms of the stem cell regulation in land plants: lesson from shoot apical cells in bryophytes2021

    • Author(s)
      Hata Yuki、Kyozuka Junko
    • Journal Title

      Plant Molecular Biology

      Volume: - Issue: 4-5 Pages: 213-225

    • DOI

      10.1007/s11103-021-01126-y

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Plant stem cell research is uncovering the secrets of longevity and persistent growth2021

    • Author(s)
      Umeda Masaaki、Ikeuchi Momoko、Ishikawa Masaki、Ito Toshiro、Nishihama Ryuichi、Kyozuka Junko、Torii Keiko U.、Satake Akiko、Goshima Gohta、Sakakibara Hitoshi
    • Journal Title

      The Plant Journal

      Volume: Online ahead of print Issue: 2 Pages: 1-10

    • DOI

      10.1111/tpj.15184

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Suppression of Leaf Blade Development by BLADE-ON-PETIOLE Orthologs Is a Common Strategy for Underground Rhizome Growth2020

    • Author(s)
      Toriba Taiyo、Tokunaga Hiroki、Nagasawa Kazuma、Nie Fanyu、Yoshida Akiko、Kyozuka Junko
    • Journal Title

      Current Biology

      Volume: 30 Issue: 3 Pages: 509-516.e3

    • DOI

      10.1016/j.cub.2019.11.055

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The origin and evolution of the ALOG proteins, members of a plant-specific transcription factor family, in land plants2020

    • Author(s)
      Naramoto Satoshi、Hata Yuki、Kyozuka Junko
    • Journal Title

      Journal of Plant Research

      Volume: 133 Issue: 3 Pages: 323-329

    • DOI

      10.1007/s10265-020-01171-6

    • NAID

      40022231058

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A conserved regulatory mechanism mediates the convergent evolution of plant shoot lateral organs.2019

    • Author(s)
      Naramoto S, Jones VAS, Nicola, N, Sato M,Toyooka K, Shimamura M, Ishida S, Nishitani K,Ishizaki K, Nishihama R, Kohchi T, Dolan L, Kyozuka J.
    • Journal Title

      PLoS Biology

      Volume: 17 Issue: 12 Pages: 12-12

    • DOI

      10.1371/journal.pbio.3000560

    • NAID

      120006813343

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] BLADE-ON-PETIOLE genes are not involved in the transition from protonema to gametophore in the moss Physcomitrella patens2019

    • Author(s)
      Hata Yuki、Naramoto Satoshi、Kyozuka Junko
    • Journal Title

      Journal of Plant Research

      Volume: 132 Issue: 5 Pages: 617-627

    • DOI

      10.1007/s10265-019-01132-8

    • NAID

      40022011601

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cytokinin signaling is essential for organ formation in Marchantia polymorpha2019

    • Author(s)
      Aki Shiori S、Mikami Tatsuya、Naramoto Satoshi、Nishihama Ryuichi、Ishizaki Kimitsune、Kojima Mikiko、Takebayashi Yumiko、Sakakibara Hitoshi、Kyozuka Junko、Kohchi Takayuki、Umeda Masaaki
    • Journal Title

      Plant and Cell Physiology

      Volume: 60 Issue: 8 Pages: 1842-1854

    • DOI

      10.1093/pcp/pcz100

    • NAID

      120006711216

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Presentation] Control of vegetative reproduction2022

    • Author(s)
      Kyozuka J, Komatsu A, Kodama K, Kumagai K, Suzuki H
    • Organizer
      第63回日本植物生理学会年会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] Analysis of the vegetative reproduction in the hornwort Anthoceros angustus2022

    • Author(s)
      Hidemasa Suzuki, Junko Kyozuka
    • Organizer
      第63回日本植物生理学会年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Control of meristem size and inflorescence architecture by APO2, a LEAFY ortholog, in rice.2021

    • Author(s)
      Kyozuka J, Yiling Miao, Chengqiang Ding
    • Organizer
      7th International symposium on plant reproductive development
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ストリゴラクトンが取り持つコケとAM菌の共生2021

    • Author(s)
      経塚淳子
    • Organizer
      日本植物学会第84回大会シンポジウム
    • Related Report
      2021 Annual Research Report
  • [Presentation] PpTAWs, ALOG transcription factors, repress stem cell activity in differentiating cell of the shoot apical meristem in Physcomitrium patens2021

    • Author(s)
      Yuki Hata, Satoshi Naramoto, Yuji Hiwatashi, Junko Kyozuka
    • Organizer
      FASEB Science Research Conference: Mechanisms in Plant Development, online
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Transcriptome approach to reveal target genes of SMXL in the liverwort Marchantia polymorpha2021

    • Author(s)
      Hidemasa Suzuki, Kazato Kumagai, Aino Komatsu, Kyoichi Kodama, and Junko Kyozuka
    • Organizer
      3rd International Congress on Strigolacones
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] メリステム制御因子TAWAWA1はヒメツリガネゴケの分化を調節する2020

    • Author(s)
      秦有輝、楢本悟史、日渡祐二、経塚淳子
    • Organizer
      日本植物学会第84回大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ゼニゴケK L信号伝達における抑制因子Mp S M X L発現のフィードバック制御2020

    • Author(s)
      小松 愛乃、水野 陽平、児玉 恭一、島崎 翔太、楢本 悟史、経塚 淳子
    • Organizer
      日本植物学会第84回大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Molecular basis to look like their age: in case of rice leaves2017

    • Author(s)
      Junko Kyozuka
    • Organizer
      The 1st IROASTSymposium 'Plant Cell and Developmental Biology:Approaaches to Multiscale Biosystems'
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Regulation of rice inflorescence architecture by a cooperative action of TAWAWA1 and BOP genes2017

    • Author(s)
      Junko Kyozuka
    • Organizer
      XIX International Botanical Congress
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Funded Workshop] TFC Symposium Plant Stem Cells: Source of Plant VItality2019

    • Related Report
      2019 Annual Research Report
  • [Funded Workshop] Marchantia Workshop2019

    • Related Report
      2019 Annual Research Report

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Published: 2017-07-04   Modified: 2024-06-05  

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