| Budget Amount *help |
¥119,210,000 (Direct Cost: ¥91,700,000、Indirect Cost: ¥27,510,000)
Fiscal Year 2022: ¥23,270,000 (Direct Cost: ¥17,900,000、Indirect Cost: ¥5,370,000)
Fiscal Year 2021: ¥23,010,000 (Direct Cost: ¥17,700,000、Indirect Cost: ¥5,310,000)
Fiscal Year 2020: ¥21,840,000 (Direct Cost: ¥16,800,000、Indirect Cost: ¥5,040,000)
Fiscal Year 2019: ¥21,060,000 (Direct Cost: ¥16,200,000、Indirect Cost: ¥4,860,000)
Fiscal Year 2018: ¥30,030,000 (Direct Cost: ¥23,100,000、Indirect Cost: ¥6,930,000)
|
|---|
| Outline of Final Research Achievements |
Germ cells are the one cell lineage that creates the next generation through formation of sperm and oocytes. In this study, we analyzed the process by which mouse male germ cells are born in the early embryo, become spermatogonial stem cells and spermatozoa, and are transmitted to the next generation. We elucidated the clonal reduction that occurs in primordial germ cells during embryogenesis, subsequent process of sperm stem cell formation, clonal competition that occurs in sperm stem cell pool, and during transmission to the next generation. Furthermore, we developed culture methods for chick primordial germ cells, consolidating the foundation for germ cell research in birds, whose germ cell formation process differs from that of mammals.
|
