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Understanding totipotency acquisition and early embryonic development in non-human primates

Planned Research

Project AreaProgram of totipotency: From decoding to designing
Project/Area Number 19H05759
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionCentral Institute for Experimental Animals

Principal Investigator

佐々木 えりか  公益財団法人実験動物中央研究所, マーモセット医学生物学研究部, 部長 (70390739)

Project Period (FY) 2019-06-28 – 2024-03-31
Project Status Granted (Fiscal Year 2023)
Budget Amount *help
¥103,090,000 (Direct Cost: ¥79,300,000、Indirect Cost: ¥23,790,000)
Fiscal Year 2023: ¥20,150,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥4,650,000)
Fiscal Year 2022: ¥20,150,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥4,650,000)
Fiscal Year 2021: ¥20,150,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥4,650,000)
Fiscal Year 2020: ¥20,150,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥4,650,000)
Fiscal Year 2019: ¥22,490,000 (Direct Cost: ¥17,300,000、Indirect Cost: ¥5,190,000)
Keywordsマーモセット / 体細胞核移植 / 着床後胚培養 / キメラ / 全能性 / 初期発生 / 初期胚発生
Outline of Research at the Start

本研究では、発生工学技術が確立しているマーモセットを用いて体細胞核移植マーモセット、キメラマーモセットなどの産仔獲得を目指すとともにマウスと霊長類の全能性の獲得と維持の分子メカニズムを明らかにする。

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Published: 2019-07-04   Modified: 2023-07-19  

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