| Budget Amount *help |
¥63,180,000 (Direct Cost: ¥48,600,000、Indirect Cost: ¥14,580,000)
Fiscal Year 2023: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Fiscal Year 2022: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Fiscal Year 2021: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Fiscal Year 2020: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Fiscal Year 2019: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
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| Outline of Final Research Achievements |
We developed conditional proteomics methods targeting copper(I) in collaboration with the Kambe team and the Ogura team. Additionally, we developed a novel light-driven proximity labeling method applicable for interactome analysis of metal-related proteins. As an unexpected achievement from the initial plan, we successfully established a system for comprehensively identifying gene sets that perturb the phenotype of phosphatidylcholine (PC) and revealed that FLVCR1, previously known as a heme transporter, is involved in PC biosynthesis. Further analysis revealed that FLVCR1 functions as a choline transporter in various cell types.
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