|Budget Amount *help
¥75,920,000 (Direct Cost: ¥58,400,000、Indirect Cost: ¥17,520,000)
Fiscal Year 2012: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
Fiscal Year 2011: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
Fiscal Year 2010: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2009: ¥26,520,000 (Direct Cost: ¥20,400,000、Indirect Cost: ¥6,120,000)
Fiscal Year 2008: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
We aim to elucidate the properties and functions such as molecular recognition of molecular films at the solid-liquid interfaces using the surface forces measurement as a main tool, and contribute to the soft interface science in a flame of biofunctional chemistry. One of the important issue for understanding biological functions is water. Therefore, we have studied the followings: (1) Interfacial water adsorbed on silica surfaces from cyclohexane at different water concentrations. We succeeded to distinguish water adsorbed by chemical interactions such as hydrogen-bonding from one by the phase separation, (2) Poly(ethylene glycol)brushes which are often used as biocompatible surfaces, (3)Specific interactions between proteins:The direct forces measurement provides useful information for nderstanding the interactions between biological molecules.