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Regulatory mechanism of the cell integrity signaling mediated by mRNA-binding proteins

Planned Research

Project AreaDiversity and asymmetry achieved by RNA program
Project/Area Number 20112008
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionKinki University

Principal Investigator

SUGIURA Reiko  近畿大学, 薬学部, 教授 (90294206)

Project Period (FY) 2008 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥99,710,000 (Direct Cost: ¥76,700,000、Indirect Cost: ¥23,010,000)
Fiscal Year 2012: ¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
Fiscal Year 2011: ¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
Fiscal Year 2010: ¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
Fiscal Year 2009: ¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
Fiscal Year 2008: ¥20,150,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥4,650,000)
KeywordsMAPキナーゼシグナル / RNA結合タンパク質 / RNA顆粒 / mRNA安定性 / 分子遺伝学 / 分裂酵母モデル生物 / 細胞内シグナル伝達 / MAPキナーゼ / mRNA結合タンパク質 / モデル生物 / 分裂酵母 / 抗がん剤感受性 / リアルタイムモニタリング / ミオシン / 細胞周期 / 細胞質分裂
Research Abstract

We identified the mRNA-binding protein Nrd1 and demonstrated that Nrd1 binds to and regulates mRNA stability of the Myosin mRNA. We also showed that Pmk1 MAPK, a homologue of ERK in fission yeast regulates the RNA-binding activity of Nrd1 in a phosphorylation-dependent manner. Moreover, Nrd1 translocated to the stress granules in a MAPK-mediated phosphorylation-dependent manner, thereby regulates stress tolerance in fission yeast.

Report

(7 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report   Self-evaluation Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (184 results)

All 2013 2012 2011 2010 2009 2008 Other

All Journal Article (31 results) (of which Peer Reviewed: 30 results) Presentation (126 results) (of which Invited: 3 results) Book (6 results) Remarks (7 results) Patent(Industrial Property Rights) (14 results) (of which Overseas: 1 results)

  • [Journal Article] The first total synthesis of Acremomannolipin A, the potential Ca2+ signal modulator with a characteristic glycolipid structure, isolated from the filamentous fungus Acremonium strictum2013

    • Author(s)
      Nozomi Tsutsui
    • Journal Title

      Tetrahedron Letters

      Volume: 54(6) Issue: 6 Pages: 451-453

    • DOI

      10.1016/j.tetlet.2012.10.128

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sip1, a Conserved AP-1 Accessory Protein, is Important for Golgi/Endosome Trafficking in Fission Yeast2012

    • Author(s)
      Yu Y, Kita A, Udo M, Katayama Y, Shintani M, Park K, Hagihara K, Umeda N, Sugiura R
    • Journal Title

      PLoS ONE

      Volume: 7(9) Issue: 9 Pages: e45324-e45324

    • DOI

      10.1371/journal.pone.0045324

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Studies on the Roles of Clathrin-Mediated Membrane Trafficking and Zinc Transporter Cis4 in the Transport of GPI-Anchored Proteins in Fission Yeast2012

    • Author(s)
      Jaiseng W, Fang Y, Ma Y, Sugiura R, Kuno T
    • Journal Title

      PLoS ONE

      Volume: 7(7) Issue: 7 Pages: 19294-19303

    • DOI

      10.1371/journal.pone.0041946

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The stress granule protein Vgl1 and poly(A)-binding protein Pab1 are required for doxorubicin resistance in fission yeast Schizosaccharomyces pombe2012

    • Author(s)
      Takahiro Morita
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: VOL.417 Issue: 1 Pages: 399-403

    • DOI

      10.1016/j.bbrc.2011.11.127

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acremomannolipin A, the potential calcium signal modulator with a characteristic glycolipid structure from the filamentous fungus Acremonium strictum2012

    • Author(s)
      Reiko Sugiura
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 22(21) Issue: 21 Pages: 6735-6739

    • DOI

      10.1016/j.bmcl.2012.08.085

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of the RNA-Binding Protein Nrd1 in Stress Granule Formation and Its Implication in the Stress Response in Fission Yeast2012

    • Author(s)
      Ryosuke Sato
    • Journal Title

      PLoS ONE

      Volume: VOL.7 Issue: 1 Pages: e29683-e29683

    • DOI

      10.1371/journal.pone.0029683

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 化学発光を利用した注射剤混合調整トレーニングシステムの実習への応用性の検討2012

    • Author(s)
      石渡俊二
    • Journal Title

      日本病院薬剤師会雑誌

      Volume: 48(2) Pages: 189-192

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of RNA-Binding Proteins in MAPK Signal Transduction Pathway2011

    • Author(s)
      Reiko Sugiura
    • Journal Title

      Journal of Signal Transduction

      Volume: VOL.2011 Pages: 8-8

    • DOI

      10.1155/2011/109746

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] カルシニューリン内因性制御因子の新たな生理機能:ダウン症候群やアルツハイマー病の謎に迫る2011

    • Author(s)
      梅田奈苗
    • Journal Title

      細胞工学

      Volume: 30(6) Pages: 606-611

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of the Small GTPase Rho3 in Golgi/Endosome Trafficking through Functional Interaction with Adaptin in Fission Yeast Ayako Kita, Cuifang Li, Yang Yu, Nanae Umeda2011

    • Author(s)
      Akira Doi, Mitsuko Yasuda, Shunji Ishiwata, Atsushi Taga, Yoshihiro Horiuchi, Reiko Sugiura
    • Journal Title

      PLoS ONE 6(2)

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Role of the Small GTPase Rho3 in Golgi/Endosome Trafficking through Functional Interaction with Adaptin in Fission Yeast2011

    • Author(s)
      Ayako Kita
    • Journal Title

      PLoS ONE

      Volume: 6(2)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of RNA-Binding Proteins in MAPK Signal Transduction Pathway2011

    • Author(s)
      Reiko Sugiura
    • Journal Title

      Journal of Signal Transduction

      Volume: (in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro assay of the interaction between Rnc1 protein and Pmp1 mRNA by affinity capillary electrophoresis with a carboxylated capillary2010

    • Author(s)
      Taga A, Satoh R, Ishiwata S, Kodama S, Sato A, Suzuki K, Sugiura R
    • Journal Title

      Journal of Pharmaceutical and Biomedical Analysis

      Volume: 53(5) Issue: 5 Pages: 1332-1337

    • DOI

      10.1016/j.jpba.2010.07.009

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] MAPKKK-dependent and -independent activation of Sty1 stress MAPK in fission yeast2010

    • Author(s)
      Zhou X, Ma Y, Sugiura R, Kobayashi D, Suzuki M, Deng L, Kuno T
    • Journal Title

      J. Biol. Chem

      Volume: 285(43) Issue: 43 Pages: 32818-32823

    • DOI

      10.1074/jbc.m110.135764

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The Cell Surface Protein Gene ecm33+ Is a Target of the Two Transcription Factors Atf1 and Mbx1 and Negatively Regulates Pmk1 MAPK Cell Integrity Signaling in Fission Yeast2010

    • Author(s)
      Takada H, Nishida A, Domae M, Kita A, Yamano Y, Uchida A, Ishiwata S,Fang Y, Zhou X, Masuko T, Kinoshita M, Kakehi K, Sugiura R
    • Journal Title

      Mol Biol Cell

      Volume: 21(4) Issue: 4 Pages: 674-85

    • DOI

      10.1091/mbc.e09-09-0810

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] In vitro assay of the interaction between Rnc1 protein and Pmp1 mRNA by affinity capillary electrophoresis with a carboxylated capillary2010

    • Author(s)
      Atsushi Taga, Ryosuke Satoh, Shunji Ishiwata, Shunji Kodama, Atsushi Sato, Kentaro Suzuki, Reiko Sugiura
    • Journal Title

      Journal of Pharmaceutical and Biomedical Analysis 53

      Pages: 1332-1337

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] The Cell Surface Protein Gene ecm33^<+> Is a Target of the Two Transcription Factors Atf1 and Mbx1 and Negatively Regulates Pmk1 MAPK Cell Integrity Signaling in Fission Yeast.2010

    • Author(s)
      Hirohumi Takada, Aiko Nishida, Mitsuhiro Domae, Ayako Kita, Yuki Yamano, Atsushi Uchida, Shunji Ishiwata, Yue Fang , Xin Zhou, Takashi Masuko, Mitsuhiro Kinoshita, Kazuaki Kakehi, Reiko Sugiura.
    • Journal Title

      Mol Biol Cell. 21(4)

      Pages: 674-685

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Isolation of a fission yeast mutant that is sensitive to valproic acid and defective in the gene encoding Ric1, a putative component of Ypt/Rab-specific GEF for Ryh1 GTPase.2010

    • Author(s)
      Yan Ma
    • Journal Title

      Mol.Genet.Genomics

      Volume: 284(3) Pages: 161-171

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MAPKKK-dependent and -independent activation of Sty1 stress MAPK in fission yeast2010

    • Author(s)
      Xin Zhou
    • Journal Title

      J.Biol.Chem.

      Volume: 285(43) Pages: 32818-32823

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro assay of the interaction between Rnc1 protein and Pmp1 mRNA by affinity capillary electrophoresis with a carboxylated capillary2010

    • Author(s)
      Atsushi Taga
    • Journal Title

      Journal of Pharmaceutical and Biomedical Analysis

      Volume: 53 Pages: 1332-1337

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Deletion mutants of AP-1 adaptin subunits display distinct phenotypes in fission yeast2009

    • Author(s)
      Ma Y, Takeuchi M, Sugiura R, Sio SO, Kuno T
    • Journal Title

      Genes Cells

      Volume: 14(8) Pages: 1015-1028

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Pleiotropic phenotypes caused by an opal nonsense mutation in an essential gene encoding HMG-CoA reductase in fission yeast2009

    • Author(s)
      Fang Y, Imagawa K, Zhou X, Kita A, Sugiura R, Jaiseng W, Kuno T
    • Journal Title

      Genes Cells

      Volume: 14(6) Issue: 6 Pages: 759-771

    • DOI

      10.1111/j.1365-2443.2009.01308.x

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The Role of the RNA-Binding Protein Nrd1 and Pmk1 MAPK in the Regulation of Myosin mRNA Stability in Fission2009

    • Author(s)
      Yeast Ryosuke Satoh, Takahiro Morita, Hirofumi Takada, Ayako Kita, Shunji Ishiwata, Akira Doi, Kanako Hagihara, Atsushi Taga, Yasuhiro Matsumura, Hideki Tohda, Reiko Sugiura.
    • Journal Title

      Mol Biol Cell. 他6件 20(9)

      Pages: 2473-2485

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Pleiotropic phenotypes caused by an opal nonsense mutation in an essential gene encoding HMG-CoA reductase in fission yeast2009

    • Author(s)
      Yue Fang
    • Journal Title

      Genes Cells 14

      Pages: 759-771

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Role of the RNA-Binding Protein Nrd1 and Pmk1 MAPK in the Regul ation of Myosin mRNA Stability in Fission Yeast2009

    • Author(s)
      佐藤亮介
    • Journal Title

      Mol Biol Cell. 20(9)

      Pages: 2473-2485

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Deletion mutants of AP-1 adaptin subunits display distinct phenotypes in fission yeast2009

    • Author(s)
      Yan Ma
    • Journal Title

      Genes Cells 14

      Pages: 1015-1028

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Cell Surface Protein Gene ecm33^+ Is a Target of the Two Transcription Factors Atf1 and Mbx1 and Negatively Regulates Pmk1 MAPK Cell Integrity Signaling in Fission Yeast2009

    • Author(s)
      Takada Hirohumi
    • Journal Title

      Mol Biol Cell. 21(4)

      Pages: 674-85

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MAPキナーゼシグナル伝達によるmRNA結合蛋白質の制御2009

    • Author(s)
      佐藤亮介
    • Journal Title

      蛋白質核酸酵素 54(16)

      Pages: 2207-2212

    • Related Report
      2009 Annual Research Report
  • [Journal Article] The Role of the RNA-Binding Protein Nrd1 and Pmk1 MAPK in the Regul ation of Myosin mRNA Stability in Fission Yeast2009

    • Author(s)
      Ryosuke Satoh
    • Journal Title

      Molecular Biology of the Cell (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular Genetic Approach to Identify Inhibitors of Signal Transduction Pathways2008

    • Author(s)
      Ishiwata S, Kuno T, Takada H, Koike A Sugiura R
    • Journal Title

      Sourcebook of Models for Biomedical Research, Humana Press Inc.

      Pages: 439-443

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cation Diffusion Facilitator Cis4 is Implicated in Golgi Membrane Trafficking via Regulating Zinc Homeostasis in Fission Yeast2008

    • Author(s)
      Yue Fang
    • Journal Title

      Mol. Biol. Cell 19(4)

      Pages: 1295-1303

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Chemical genetic analysis of the Ca2+/calcineurin signaling2013

    • Author(s)
      Reiko Sugiura
    • Organizer
      10th International Conference on Protein Phosphatase
    • Place of Presentation
      国際研究交流会館(東京)
    • Year and Date
      2013-02-07
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Spatial regulatory mechanism of the Pl4,5P2 signaling pathway by membrane trafficking system2013

    • Author(s)
      Cuifang Li
    • Organizer
      10th International Conference on Protein Phosphatase
    • Place of Presentation
      国際研究交流会館(東京)
    • Year and Date
      2013-02-07
    • Related Report
      2012 Annual Research Report
  • [Presentation] A role of Sip1,a clathrin adaptor ap-1 complex binding protein and Ca2+/calcineurin signaling in membrane trafficking2013

    • Author(s)
      Yang Yu
    • Organizer
      10th International Conference on Protein Phosphatase
    • Place of Presentation
      国際研究交流会館(東京)
    • Year and Date
      2013-02-07
    • Related Report
      2012 Annual Research Report
  • [Presentation] MAPKシグナル伝達経路とTRPチャネルVic2の機能的関連2012

    • Author(s)
      芦田 昌樹
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      マリンメッセ福岡(福岡)
    • Year and Date
      2012-12-14
    • Related Report
      2012 Annual Research Report
  • [Presentation] ケミカルバイオロジーの手法を用いた、カルシニューリンの新たな転写標的遺伝子tcp1+の同定と発現メカニズムの解明2012

    • Author(s)
      八百 麻里子
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      マリンメッセ福岡(福岡)
    • Year and Date
      2012-12-14
    • Related Report
      2012 Annual Research Report
  • [Presentation] Skb5はスキャッフォールドタンパク質として、PKC/ MAPKシグナルを負に制御する2012

    • Author(s)
      成瀬 一
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      マリンメッセ福岡(福岡)
    • Year and Date
      2012-12-14
    • Related Report
      2012 Annual Research Report
  • [Presentation] クラスリンアダプターAP-1複合体結合タンパク質Its4/Sip1によるCa2+シグナル制御メカニズムの解明2012

    • Author(s)
      于陽
    • Organizer
      酵母遺伝学フォーラム 第45回研究報告会
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2012-09-04
    • Related Report
      2012 Annual Research Report
  • [Presentation] PHドメインタンパク質Slp2によるイノシトールリン脂質シグナルの制御2012

    • Author(s)
      李 翠芳
    • Organizer
      酵母遺伝学フォーラム 第45回研究報告会
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2012-09-04
    • Related Report
      2012 Annual Research Report
  • [Presentation] MAPKシグナル依存的なRNA結合蛋白質Rnc1のStress Granule局在2012

    • Author(s)
      伊藤祐奈
    • Organizer
      第14回日本RNA学会年会
    • Place of Presentation
      仙台(宮城)
    • Year and Date
      2012-07-18
    • Related Report
      2012 Annual Research Report
  • [Presentation] Regulation of MAPK Signaling by Nuclear-Cytoplasmic Shuttling of the RNA-Binding Protein Rnc1 in Fission Yeast2012

    • Author(s)
      Ryosuke Satho
    • Organizer
      The 22nd CDB Meeting RNA Sciences in Cell and Developmental Biology II
    • Place of Presentation
      理化学研究所(兵庫)
    • Year and Date
      2012-06-11
    • Related Report
      2012 Annual Research Report
  • [Presentation] MAPK Signaling and RNA-granules Formation in Fission Yeast2012

    • Author(s)
      Reiko Sugiura
    • Organizer
      The 22nd CDB Meeting RNA Sciences in Cell and Developmental Biology II
    • Place of Presentation
      理化学研究所(兵庫)
    • Year and Date
      2012-06-11
    • Related Report
      2012 Annual Research Report
  • [Presentation] 細胞内輸送とイノシトールリン脂質シグナル伝達経路の機能的関係2012

    • Author(s)
      李 翠芳
    • Organizer
      第54回日本脂質生化学会
    • Place of Presentation
      九州大学医学部(福岡)
    • Year and Date
      2012-06-07
    • Related Report
      2012 Annual Research Report
  • [Presentation] S1P受容体調節剤FTY720の標的遺伝子の解析から導き出されるシグナル伝達経路機構2012

    • Author(s)
      萩原 加奈子
    • Organizer
      日本ケミカルバイオロジー学会第7回年会
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2012-06-07
    • Related Report
      2012 Annual Research Report
  • [Presentation] 酵母モデル生物を用いたMAPキナーゼシグナル制御因子の同定と創薬への展開2012

    • Author(s)
      杉浦 麗子
    • Organizer
      日本ケミカルバイオロジー学会第7回年会
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2012-06-07
    • Related Report
      2012 Annual Research Report
  • [Presentation] 細胞内シグナル伝達による核酸結合タンパク質の制御機構の解析:アフィニティキャピラリー電気泳動の応用と創薬への展開2012

    • Author(s)
      杉浦麗子
    • Organizer
      第62回日本電気泳動学会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2012-05-11
    • Related Report
      2012 Final Research Report
  • [Presentation] MAPK Signaling and RNA-granules Formation in Fission Yeast2012

    • Author(s)
      Reiko Sugiura
    • Organizer
      The 22nd CDB Meeting RNA Sciences in Cell and Developmental Biology II
    • Place of Presentation
      Kobe
    • Related Report
      2012 Final Research Report
  • [Presentation] 「細胞内シグナル伝達による核酸結合タンパク質の制御機構の解析:アフィニティキャピラリー電気泳動の応用と創薬への展開」2012

    • Author(s)
      杉浦 麗子
    • Organizer
      第62回日本電気泳動学会シンポジウム
    • Place of Presentation
      慶應義塾大学薬学部(東京)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Mitogen-activated Protein Kinase Pathway Regulation: Role of RNA-Binding Proteins in MAPK Signal Transduction Pathway2012

    • Author(s)
      Reiko Sugiura
    • Organizer
      Special Course on Global Medical Science
    • Place of Presentation
      神戸大学(兵庫)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Functional genomics of calcineurin in model organism2012

    • Author(s)
      Reiko Sugiura
    • Organizer
      From Genomics to Proteomics~Toward Understanding Gene Function andthe Mechanism of Diseases~
    • Place of Presentation
      近畿大学(大阪)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 「ゲノム薬理研究が医療の革命を起こす:~遺伝子検査からがんのテーラーメード(個別)医療まで~」2012

    • Author(s)
      杉浦麗子
    • Organizer
      第3回日本ゲノム薬理学研究会講演会
    • Place of Presentation
      神戸大学(兵庫)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Pmk1 MAPK 経路とTRP チャネルVic2 の機能的関連2012

    • Author(s)
      小野 太貴
    • Organizer
      第62回日本薬学会近畿支部総会・大会
    • Place of Presentation
      武庫川女子大学(兵庫)
    • Related Report
      2012 Annual Research Report
  • [Presentation] DEAD Box 型RNA helicase Ded1 のRNA granule 局在と機能の関わり2012

    • Author(s)
      辻本翔
    • Organizer
      第62回日本薬学会近畿支部総会・大会
    • Place of Presentation
      武庫川女子大学(兵庫)
    • Related Report
      2012 Annual Research Report
  • [Presentation] クラスリンアダプターAP-1 複合体結合タンパク質Its4/Sip1 の細胞内膜輸送における役割2012

    • Author(s)
      片山雄大
    • Organizer
      第62回日本薬学会近畿支部総会・大会
    • Place of Presentation
      武庫川女子大学(兵庫)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ゲノム薬理学的アプローチを用いたMAPKシグナル経路構成因子TRP チャネルVic2 の同定と機能解析2012

    • Author(s)
      芦田 昌樹
    • Organizer
      第122回日本薬理学会近畿部会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ケミカルバイオロジーの手法を用いた、カルシニューリンの新たな転写標的遺伝子tcp1+の同定と発現メカニズムの解明2012

    • Author(s)
      八百 麻里子
    • Organizer
      第122回日本薬理学会近畿部会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Skb5はスキャッフォールドタンパク質として、PKC/ MAPKシグナルを負に制御する2012

    • Author(s)
      成瀬 一
    • Organizer
      第122回日本薬理学会近畿部会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 細胞内輸送とイノシトールリン脂質シグナル伝達経路の機能的関係2012

    • Author(s)
      李翠芳
    • Organizer
      第5回日本プロテインホスファターゼ研究会学術集会
    • Place of Presentation
      大阪大学(大阪)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新規免疫抑制薬感受性原因遺伝子its4^+のメンブレントラフィックにおける役割2012

    • Author(s)
      于陽
    • Organizer
      第5回日本プロテインホスファターゼ研究会学術集会
    • Place of Presentation
      大阪大学(大阪)
    • Related Report
      2011 Annual Research Report
  • [Presentation] クラスリンアダプターAP-1複合体結合タンパク質Its4のメンブレントラフィックにおける役割2012

    • Author(s)
      有働雅子
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学(北海道)
    • Related Report
      2011 Annual Research Report
  • [Presentation] RNA結合蛋白質Nrd1のStress Granules形成とストレス応答における働き2012

    • Author(s)
      田中章友
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学(北海道)
    • Related Report
      2011 Annual Research Report
  • [Presentation] SIP受容体調節薬FTY720の標的遺伝子の同定と遺伝子発現機構の解明2012

    • Author(s)
      水庫彩
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学(北海道)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 抗がん剤汚染防止用ゴム栓「もれま栓」の検討2012

    • Author(s)
      石渡俊二
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学(北海道)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新規Calcineurinシグナル拮抗物質AcremomannolipinAの構造2012

    • Author(s)
      筒井望
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学(北海道)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Novel functional roles for calcineurin inhibitor RCAN12011

    • Author(s)
      Reiko Sugiura
    • Organizer
      The First Japan-Taiwan Bilateral Conference on Protein Phosphatases
    • Place of Presentation
      自然科学研究機構基礎生物学研究所(愛知)
    • Year and Date
      2011-12-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] 低分子量Gタンパク質Rho3とクラスリンアダプター複合体の細胞内輸送システムにおける機能的関連2011

    • Author(s)
      喜多綾子
    • Organizer
      第120回日本薬理学会近畿部会
    • Place of Presentation
      ホテルグランビア京都(京都)
    • Year and Date
      2011-11-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] PKC抑制因子であるDed1の機能解析2011

    • Author(s)
      比嘉真理
    • Organizer
      第120回日本薬理学会近畿部会
    • Place of Presentation
      ホテルグランビア京都(京都)
    • Year and Date
      2011-11-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] PKC/MAPK経路とRNAhelicase Ded1の機能的関連の研究-Pck2に対するDed1の影響の研究2011

    • Author(s)
      成瀬一、土井章、喜多綾子、比嘉真理、梅田奈苗、杉浦麗子
    • Organizer
      第61回日本薬学会近畿支部総会・大会
    • Place of Presentation
      神戸
    • Year and Date
      2011-10-22
    • Related Report
      2012 Final Research Report
  • [Presentation] カルシニューリンの内因性制御因子DSCR1の分裂酵母ホモログCbp1が細胞内シグナル伝達経路に与える影響の解析2011

    • Author(s)
      清瀬好美
    • Organizer
      第61回日本薬学会近畿支部総会・大会
    • Place of Presentation
      神戸学院大学(兵庫)
    • Year and Date
      2011-10-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] MADSbox型転写因子Mbx1は新規トランスポーターDom1を介してCa2+ホメオスタシスを制御する2011

    • Author(s)
      芦田昌樹
    • Organizer
      第61回日本薬学会近畿支部総会・大会
    • Place of Presentation
      神戸学院大学(兵庫)
    • Year and Date
      2011-10-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] PKC/MAPK経路とRNAhelicase Ded1の機能的関連の研究-Pck2に対するDed1の影響の研究2011

    • Author(s)
      成瀬一
    • Organizer
      第61回日本薬学会近畿支部総会・大会
    • Place of Presentation
      神戸学院大学(兵庫)
    • Year and Date
      2011-10-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] 免疫抑制薬FTY720の標的遺伝子の同定と遺伝子発現メカニズムの解析-FTY720とCa2+シグナル伝達機構の関係2011

    • Author(s)
      八百麻里子
    • Organizer
      第61回日本薬学会近畿支部総会・大会
    • Place of Presentation
      神戸学院大学(兵庫)
    • Year and Date
      2011-10-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] A powerful genetic strategy to screen for inhibitors of MAPK signaling and its application to genomic drug discovery2011

    • Author(s)
      Reiko Sugiura
    • Organizer
      A New Wave of Chemical Genomics
    • Place of Presentation
      近畿大学(大阪)
    • Year and Date
      2011-09-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 酵母モデル生物を用いたMAPキナーゼシグナル制御機構の解明と創薬への展開2011

    • Author(s)
      杉浦麗子
    • Organizer
      第73回酵母研究会
    • Place of Presentation
      甲南大学(神戸)
    • Year and Date
      2011-09-13
    • Related Report
      2011 Annual Research Report
  • [Presentation] A Powerful Genetic Strategy to Screen for Inhibitors of MAP kinase Signalling Reiko Sugiura2011

    • Author(s)
      Reiko Sugiura
    • Organizer
      THE SIXTH INTERNATIONAL FISSION YEAST MEETING, pombe2011
    • Place of Presentation
      Boston
    • Related Report
      2012 Final Research Report
  • [Presentation] Role of RNA-Blnding Proteins in MAPK Signal Transduction Pathway2011

    • Author(s)
      Reiko Sugiura
    • Organizer
      RNA 2011 Sixteenth Annual Meeting of the RNA Society (RNA 2011 Kyoto)
    • Place of Presentation
      国立京都国際会館(京都)
    • Related Report
      2011 Annual Research Report
  • [Presentation] MAP kinase signaling-dependent regulation of stress granule formation mediated by the RNA-binding protein Nrd1 in fission yeast2011

    • Author(s)
      Ryosuke Satoh
    • Organizer
      RNA 2011 Sixteenth Annual Meeting of the RNA Society (RNA 2011 Kyoto)
    • Place of Presentation
      国立京都国際会館(京都)
    • Related Report
      2011 Annual Research Report
  • [Presentation] A Powerful Genetic Strategy to Screen for Inhibitors of MAP kinase Signalling2011

    • Author(s)
      Reiko Sugiura
    • Organizer
      THE SIXTH INTERNATIONAL FISSION YEAST MEETING
    • Place of Presentation
      Harvard Medical School Martin Conference Center (Boston)
    • Related Report
      2011 Annual Research Report
  • [Presentation] The cell surface protein Ecm33 negatively regulates Pmk1 MAPK signaling via Ca2+ homeostasis2011

    • Author(s)
      Mitsuhiro Domae
    • Organizer
      THE SIXTH INTERNATIONAL FISSION YEAST MEETING
    • Place of Presentation
      Harvard Medical School Martin Conference Center (Boston)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Spatial regulatory mechanism of the PI4,5P2 signaling pathway by membrane trafficking system2011

    • Author(s)
      Cuifang Li
    • Organizer
      THE SIXTH INTERNATIONAL FISSION YEAST MEETING
    • Place of Presentation
      Harvard Medical School Martin Conference Center (Boston)
    • Related Report
      2011 Annual Research Report
  • [Presentation] MAP kinase signaling regulates stress granule formation via the RNA-binding protein Nrd12011

    • Author(s)
      Ryosuke Satoh
    • Organizer
      THE SIXTH INTERNATIONAL FISSION YEAST MEETING
    • Place of Presentation
      Harvard Medical School Martin Conference Center (Boston)
    • Related Report
      2011 Annual Research Report
  • [Presentation] The MADS-box transcription factor Mbx1 controls Ca2+ homeostasis via the regulation of dom1+2011

    • Author(s)
      Atsushi Uchida
    • Organizer
      THE SIXTH INTERNATIONAL FISSION YEAST MEETING
    • Place of Presentation
      Harvard Medical School Martin Conference Center (Boston)
    • Related Report
      2011 Annual Research Report
  • [Presentation] A Rule for Its'4, a Clathrin Adaptor Ap-1 Complex Binding Protein, in Membrane Trafficking2011

    • Author(s)
      Yang Yu
    • Organizer
      THE SIXTH INTERNATIONAL FISSION YEAST MEETING
    • Place of Presentation
      Harvard Medical School Martin Conference Center (Boston)
    • Related Report
      2011 Annual Research Report
  • [Presentation] RNA分解システムとPKC/MAPKシグナル伝達経路の関わり2011

    • Author(s)
      土井章
    • Organizer
      RNAフロンティアミーティング2011
    • Place of Presentation
      あいち健康プラザ(愛知)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 分裂酵母遺伝子ノックアウトコレクションを用いた新規Pmk1 MAPK経路構成因子のスクリーニング2011

    • Author(s)
      吉村美耶
    • Organizer
      酵母遺伝学フォーラム第44回研究報告会
    • Place of Presentation
      九州大学医学部百年講堂(福岡)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 細胞内輸送システムによるイノシトールリン脂質シグナル伝達経路の空間的制御機構2011

    • Author(s)
      李翠芳
    • Organizer
      酵母遺伝学フォーラム第44回研究報告会
    • Place of Presentation
      九州大学医学部百年講堂(福岡)
    • Related Report
      2011 Annual Research Report
  • [Presentation] クラスリンアダプターAP-1複合体結合タンパク質Its4のメンブレントラッフィックにおける役割2011

    • Author(s)
      于陽
    • Organizer
      酵母遺伝学フォーラム第44回研究報告会
    • Place of Presentation
      九州大学医学部百年講堂(福岡)
    • Related Report
      2011 Annual Research Report
  • [Presentation] MAPKシグナル依存的なRNA結合蛋白質Nrd1によるStress Granule形成機構2011

    • Author(s)
      佐藤亮介
    • Organizer
      酵母遺伝学フォーラム第44回研究報告会
    • Place of Presentation
      九州大学医学部百年講堂(福岡)
    • Related Report
      2011 Annual Research Report
  • [Presentation] MADS-box型転写因子Mbx1の新規membrane transporter dom1+を介したCa2+ホメオスタシス制御機構の解明2011

    • Author(s)
      内田篤史
    • Organizer
      酵母遺伝学フォーラム第44回研究報告会
    • Place of Presentation
      九州大学医学部百年講堂(福岡)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 分裂酵母モデル生物を用いたカルシニューリン内因性制御因子RCAN/DSCR1ホモログの新たな生理機能の解明2011

    • Author(s)
      杉浦麗子
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都)
    • Related Report
      2011 Annual Research Report
  • [Presentation] The Actin Binding Protein Cis3/PSTPIP Is Involved in the Regulation of the Pmk1 MAPK Signaling Pathway and Cytokinesis2011

    • Author(s)
      Akihiro Takeda
    • Organizer
      1st International Symposium on Carcinogenic Spiral & 9th International Conference on Protein Phosphatase
    • Place of Presentation
      東京大学(東京)
    • Related Report
      2010 Annual Research Report
  • [Presentation] MADS-Box Transcription Factor Mbx1 Is Involved in the Regulation of Calcineurin Signaling through Ca2+-Homeostasis Modulation2011

    • Author(s)
      Yuki Yamano
    • Organizer
      1st International Symposium on Carcinogenic Spiral & 9th International Conference on Protein Phosphatase
    • Place of Presentation
      東京大学(東京)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Stress-Activated Protein Kinase Signaling Regulates Ca2+-Calcineurin Signaling2011

    • Author(s)
      Daiki Kanbayashi
    • Organizer
      1st International Symposium on Carcinogenic Spiral & 9th International Conference on Protein Phosphatase
    • Place of Presentation
      東京大学(東京)
    • Related Report
      2010 Annual Research Report
  • [Presentation] A Powerful Genetic Strategy to Screen for Inhibitors of MAP kinase Signalling and Its Application to Genomic Drug Discovery2011

    • Author(s)
      Reiko Sugiura
    • Organizer
      1st International Symposium on Carcinogenic Spiral & 9th International Conference on Protein Phosphatase
    • Place of Presentation
      東京大学(東京)
    • Related Report
      2010 Annual Research Report
  • [Presentation] ダウン症候群原因遺伝子の新たな役割の発見~がん化とストレスとの関係性~2011

    • Author(s)
      上林大起
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      ツインメッセ静岡(静岡)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 低分子量Gタンパク質Rho2を介すシグナル伝達経路の新たな制御メカニズム2011

    • Author(s)
      近藤大貴
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      ツインメッセ静岡(静岡)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 抗がん剤汚染防止バイアル用ゴム栓「もれま栓」プロトタイプの開発2011

    • Author(s)
      石渡俊二
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      ツインメッセ静岡(静岡)
    • Related Report
      2010 Annual Research Report
  • [Presentation] キャピラリー電気泳動を用いる個々の注射剤容器からの漏液量低コスト簡易測定法の開発2011

    • Author(s)
      多賀淳
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      ツインメッセ静岡(静岡)
    • Related Report
      2010 Annual Research Report
  • [Presentation] DSCR1の分裂酵母ホモログCbp1を介するCNシグナルとMAPKシグナル伝達経路のクロストーク2010

    • Author(s)
      梅田奈苗
    • Organizer
      第118回 日本薬理学会近畿部会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Year and Date
      2010-11-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規免疫抑制薬FTY720のターゲット遺伝子の同定と作用メカニズムの解析2010

    • Author(s)
      水庫彩
    • Organizer
      第60回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      摂南大学(大阪)
    • Year and Date
      2010-10-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] クラスリンアダプター複合体とRNA結合タンパク質の新たなクロストーク機構2010

    • Author(s)
      有働雅子
    • Organizer
      第60回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      摂南大学(大阪)
    • Year and Date
      2010-10-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 細胞内表面蛋白質Ecm33による細胞内Ca2+濃度の制御メカニズムの解析2010

    • Author(s)
      園田健展
    • Organizer
      第60回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      摂南大学(大阪)
    • Year and Date
      2010-10-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] MAPKシグナル依存的に遺伝子発現が制御される細胞表面タンパク質Ecm33の機能解析とin vivo real-time MAPKシグナルモニタリングシステムの確立2010

    • Author(s)
      高田宏文
    • Organizer
      第60回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      摂南大学(大阪)
    • Year and Date
      2010-10-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecular genetic approach to identify regulators of MAPK signaling2010

    • Author(s)
      Reiko Sugiura
    • Organizer
      IMC9 THE BIOLOGY OF FUNGI
    • Place of Presentation
      Edinburgh, UK
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] RNAを介するMAPキナーゼシグナルの新たな制御機構と創薬への展望2010

    • Author(s)
      杉浦麗子
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Related Report
      2012 Final Research Report 2010 Self-evaluation Report 2009 Annual Research Report
  • [Presentation] RNA-Binding Proteins as Regulators of MAPK Signaling2010

    • Author(s)
      Reiko Sugiura
    • Organizer
      The 19^<th> CDB Meeting RNA Sciences in Cell and Developmental Biology
    • Place of Presentation
      理化学研究所 発生・再生医療センター(神戸)
    • Related Report
      2010 Annual Research Report
  • [Presentation] MAP Kinase Signaling Dependent Regulation of Cell Fate Mediated by the RNA-binding protein Nrd1 in Fission yeast2010

    • Author(s)
      Ryosuke Satoh
    • Organizer
      The 19^<th> CDB Meeting RNA Sciences in Cell and Developmental Biology
    • Place of Presentation
      理化学研究所 発生・再生医療センター(神戸)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Functional Relationship between MAP kinase Signaling and Pumilio in Fission Yeast2010

    • Author(s)
      Kanako Hagihara
    • Organizer
      The 19^<th> CDB Meeting RNA Sciences in Cell and Developmental Biology
    • Place of Presentation
      理化学研究所 発生・再生医療センター(神戸)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 核内核外輸送を介したRNA結合タンパク質Rnc1の機能解析2010

    • Author(s)
      松村康弘
    • Organizer
      第12回日本RNA学会年会
    • Place of Presentation
      一橋記念講堂(東京)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Protein Kinase Cシグナル伝達経路の新規制御因子であるRNA helicase Ded1とP-body局在の機能解析2010

    • Author(s)
      加藤綾歌
    • Organizer
      第12回日本RNA学会年会
    • Place of Presentation
      一橋記念講堂(東京)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 分裂酵母におけるRNA結合タンパク質Sts5はRho/プロテインキナーゼC/MAPKシグナルを制御する2010

    • Author(s)
      高田宏文
    • Organizer
      第12回日本RNA学会年会
    • Place of Presentation
      一橋記念講堂(東京)
    • Related Report
      2010 Annual Research Report
  • [Presentation] RNA結合蛋白質Nrd1はMAPKシグナル依存的に環境ストレス応答を制御する2010

    • Author(s)
      佐藤亮介
    • Organizer
      第1回RNA Study Meeting本会
    • Place of Presentation
      一橋記念講堂(東京)
    • Related Report
      2010 Annual Research Report
  • [Presentation] The Cell Surface Protein Ecm33 Negatively Regulates the Pmk1 Mapk Signalling Via Ca^<2+> Control2010

    • Author(s)
      Mitsuhiro Domae
    • Organizer
      IMC9 THE BIOLOGY OF FUNGI
    • Place of Presentation
      Edinburgh, UK
    • Related Report
      2010 Annual Research Report
  • [Presentation] アクチン結合タンパク質Cis3とMAPキナーゼ経路のクロストークによる細胞質分裂の制御2010

    • Author(s)
      武田章弘
    • Organizer
      酵母遺伝学フォーラム 第43回研究報告会
    • Place of Presentation
      ならまちセンター(奈良)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 低分子量Gタンパク質Rab GTPaseを介した細胞膜輸送システムによるイノシトールリン脂質合成酵素PI(4)P5Kの制御メカニズム2010

    • Author(s)
      李翠芳
    • Organizer
      酵母遺伝学フォーラム 第43回研究報告会
    • Place of Presentation
      ならまちセンター(奈良)
    • Related Report
      2010 Annual Research Report
  • [Presentation] MADs-box型転写因子Mbx1のExportinによる局在制御と転写活性への影響2010

    • Author(s)
      山野有希
    • Organizer
      酵母遺伝学フォーラム 第43回研究報告会
    • Place of Presentation
      ならまちセンター(奈良)
    • Related Report
      2010 Annual Research Report
  • [Presentation] MADs-box型転写因子Mbx1の標的因子の同定とCa2+/Calcineurinシグナル伝達経路における役割2010

    • Author(s)
      内田篤史
    • Organizer
      酵母遺伝学フォーラム 第43回研究報告会
    • Place of Presentation
      ならまちセンター(奈良)
    • Related Report
      2010 Annual Research Report
  • [Presentation] クラスリンアダプターAP-1複合体結合タンパク質Its4のメンブレントラフィックにおける役割2010

    • Author(s)
      于陽
    • Organizer
      酵母遺伝学フォーラム 第43回研究報告会
    • Place of Presentation
      ならまちセンター(奈良)
    • Related Report
      2010 Annual Research Report
  • [Presentation] RNA結合蛋白質Nrd1はMAPKシグナル依存的にStress Granule形成を制御する2010

    • Author(s)
      佐藤亮介
    • Organizer
      酵母遺伝学フォーラム 第43回研究報告会
    • Place of Presentation
      ならまちセンター(奈良)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 細胞表面膜タンパク質Ecm33による細胞統御シグナル制御機構2010

    • Author(s)
      堂前光宏
    • Organizer
      酵母遺伝学フォーラム 第43回研究報告会
    • Place of Presentation
      ならまちセンター(奈良)
    • Related Report
      2010 Annual Research Report
  • [Presentation] レーザー励起蛍光検出キャピラリー電気泳動を用いる不均一性タンパク質の結合能評価2010

    • Author(s)
      多賀淳
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学(仙台)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Simultaneous Binding Assay ofMicroheterogenious Proteins by Capillary Electrophoresis with Laser InducedFluorescence Detection.2010

    • Author(s)
      Atsushi Taga
    • Organizer
      16th International Symposium on Separation Science
    • Place of Presentation
      Rome
    • Related Report
      2010 Annual Research Report
  • [Presentation] MADS-box型転写因子Mbx1は新規membrane transporter dom1+を介してCa2+ホメオスタシスを制御する2010

    • Author(s)
      内田篤史
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Related Report
      2010 Annual Research Report
  • [Presentation] 膜表面タンパク質Ecm33による細胞統御シグナル制御機構2010

    • Author(s)
      堂前光宏
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Related Report
      2010 Annual Research Report
  • [Presentation] Protein Kinase Cシグナル伝達経路の新規制御因子である RNA helicase Ded1とP-body 局在の機能的関連2010

    • Author(s)
      土井章
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Related Report
      2009 Annual Research Report
  • [Presentation] DSCR1(Down Syndrome Critical Region 1)ホモログCbp1のリン酸化依存的機能がCa^<2+>/カルシニューリンシグナルに与える影響の解析2010

    • Author(s)
      川北麻貴
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Related Report
      2009 Annual Research Report
  • [Presentation] カルシニューリンの内因性制御因子DSCR1ホモログを介するカルシウムシグナルとストレス応答MAPKシグナルのクロストーク制御2010

    • Author(s)
      上林大起
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Related Report
      2009 Annual Research Report
  • [Presentation] MAPKシグナル依存的な2つの転写因子Atf1およびMbx1によって遺伝子発現が制御される新規遺伝子tpa1^+の機能解析:~ in vivo real-time MAPキナーゼシグナル依存的転写活性測定システムの確立と応用~2010

    • Author(s)
      高田宏文
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Related Report
      2009 Annual Research Report
  • [Presentation] 低分子量Gタンパク質 Rab GTPase を介した細胞膜輸送システムによるイノシトールリン脂質合成酵素PI(4)P5Kの制御メカニズム2010

    • Author(s)
      李翠芳
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Related Report
      2009 Annual Research Report
  • [Presentation] RNA結合タンパク質Nrd1はMAPキナーゼシグナル依存的に細胞運命を制御する2010

    • Author(s)
      佐藤亮介
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Related Report
      2009 Annual Research Report
  • [Presentation] アクチン結合タンパク質Cis3とMAPキナーゼ経路のクロストーク2010

    • Author(s)
      高部朋幸
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Related Report
      2009 Annual Research Report
  • [Presentation] ゲノム薬理学的手法とケミカルバイオロジーを用いた新規免疫抑制薬FTY720の標的遺伝子の発現と細胞内カルシウムシグナル伝達経路に与える影響の解析2010

    • Author(s)
      萩原加奈子
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Related Report
      2009 Annual Research Report
  • [Presentation] アフィニティーキャピラリー電気泳動によるRNA-GFP-タンパク質相互作用の観察2010

    • Author(s)
      多賀淳
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Related Report
      2009 Annual Research Report
  • [Presentation] 化学発光を用いた注射剤混合トレーニングシステムの開発2010

    • Author(s)
      石渡俊二
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Related Report
      2009 Annual Research Report
  • [Presentation] クラスリンアダプター複合体μ1サブユニットApm1の制御因子としての低分子量Gタンパク質Rho3の発見とゴルジ・エンドゾームにおける働き2009

    • Author(s)
      李翠芳
    • Organizer
      第59回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] MAPK/Atf1(CREB)シグナルの新たな標的遺伝子tpa1^+のプロモーター解析とMAPKシグナル伝達経路における役割2009

    • Author(s)
      堂前光宏
    • Organizer
      第59回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] ノックアウトコレクションを用いたMAPキナーゼシグナローム構成因子の同定と機能解析2009

    • Author(s)
      吉村美耶
    • Organizer
      第59回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規クラスリンアダプターAP-1複合体結合タンパク質Its4のメンブレンントラッフィックにおける役割2009

    • Author(s)
      于陽
    • Organizer
      第59回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] MADS-box 型転写因子Mbx1の局在制御メカニズムがCa^<2+>ホメオスタシスに与える影響の解析2009

    • Author(s)
      内田篤史
    • Organizer
      第59回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規免疫抑制薬FTY720の標的遺伝子の同定と細胞内Ca2+シグナル伝達経路における役割の解析2009

    • Author(s)
      萩原加奈子
    • Organizer
      第59回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] カルシニューリンの内因性制御因子DSCR1ホモログの新たな標的分子の同定2009

    • Author(s)
      上林大起
    • Organizer
      第59回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] RNA-BINDING PROTEINS AS REGURATORS OF MAPK SIGNALING2009

    • Author(s)
      Reiko Sugiura
    • Organizer
      The 5th International Fission Yeast Meeting (Pombe 2009)
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] MAPキナーゼシグナル伝達によるmRNA結合タンパク質の制御2009

    • Author(s)
      杉浦麗子
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Related Report
      2012 Final Research Report 2009 Annual Research Report
  • [Presentation] RNA-BINDING PROTEINS AS REGURATORS OF MAPK SIGNALING2009

    • Author(s)
      Reiko Sugiura
    • Organizer
      The 5th International Fission Yeast Meeting (Pombe 2009) 他70件
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] 分裂酵母におけるRNA結合タンパク質Nrd1によるMAPキナーゼシグナル依存的な細胞運命制御機構2009

    • Author(s)
      佐藤亮介
    • Organizer
      第11回 日本RNA学会年会
    • Place of Presentation
      新潟
    • Related Report
      2009 Annual Research Report
  • [Presentation] Observation of Interaction between RNA and GFP-Protein by Affinity Capillary Electrophoresis2009

    • Author(s)
      多賀淳
    • Organizer
      ISPPP 2009-International Symposium on the S eparation of Proteins, Peptides and Polynucleotides
    • Place of Presentation
      Florida, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] RNA-BINDING PROTEINS AS REGURATORS OF MAPK SIGNALING2009

    • Author(s)
      杉浦麗子
    • Organizer
      The 5th International Fission Yeast Meeting(Pombe 2009)
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] MAPK SIGNALING-DEPENDENT REGULATION OF CELL FATE MEDIATED BY THE RNA-BINDING PROTEIN Nrd12009

    • Author(s)
      佐藤亮介
    • Organizer
      The 5th International Fission Yeast Meeting(Pombe 2009)
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] A NOVEL CELL SURFACE PROTEIN TPA1 ACTS AS A NEGATIVE REGULATOR OF THE PMK1 MAPK SIGNALING2009

    • Author(s)
      高田宏文
    • Organizer
      The 5th International Fission Yeast Meeting(Pombe 2009)
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] A Role of Its4, A Clathrin-Associated Adaptor-Protein-1 Complex(AP-1)binding protein, in membrane trafficKING of Fission Yeast2009

    • Author(s)
      于陽
    • Organizer
      The 5th International Fission Yeast Meeting(Pombe 2009)
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] MAPキナーゼによるリン酸化依存的なRNA結合タンパク質Nrd1の細胞運命制御機構2009

    • Author(s)
      佐藤亮介
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Related Report
      2009 Annual Research Report
  • [Presentation] アクチン結合タンパク質Cis3のMAPキナーゼによるリン酸化制御2009

    • Author(s)
      高村暁
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] RNA結合蛋白質Sts5とリン酸化シグナル伝達の機能的関係2009

    • Author(s)
      酒井喜裕
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] 低分子量Gタンパク質Rho2を介するシグナル伝達経路の新たな制御メカニズム2009

    • Author(s)
      竹島沙織
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] Molecular Genetic Analysis of the Calcineurin-mediated Signaling Pathways2008

    • Author(s)
      Reiko Sugiura
    • Organizer
      8th International Conference on Protein Phosphatases
    • Place of Presentation
      Maebashi
    • Related Report
      2012 Final Research Report
  • [Presentation] RNA結合タンパク質Nrd1による細胞運命スイッチングの制御機構2008

    • Author(s)
      佐藤亮介、森田貴大、高田宏文、萩原加奈子、土井章、喜多綾子、石渡俊二、杉浦麗子
    • Organizer
      酵母遺伝学フォーラム第41回研究報告会
    • Place of Presentation
      北海道
    • Related Report
      2012 Final Research Report
  • [Presentation] RNA結合タンパク質Nrd1による細胞運命スイッチングの制御機構2008

    • Author(s)
      佐藤亮介
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report
  • [Book] 岩波生物学辞典 第5版2013

    • Author(s)
      杉浦麗子
    • Total Pages
      2192
    • Publisher
      岩波書店
    • Related Report
      2012 Final Research Report
  • [Book] 生物学辞典 第5版2013

    • Author(s)
      巌佐 庸
    • Total Pages
      2000
    • Publisher
      岩波書店
    • Related Report
      2012 Annual Research Report
  • [Book] 医薬品の開発と生産 レギュラとリーサイエンスの基礎2010

    • Author(s)
      杉浦麗子、石渡俊二 編者 永井恒司、園部尚
    • Publisher
      じほう
    • Related Report
      2012 Final Research Report
  • [Book] Welcome to ゲノムワールド ゲノム創薬科学最前線2009

    • Author(s)
      杉浦麗子編著
    • Total Pages
      264
    • Publisher
      京都廣川書店
    • Related Report
      2012 Final Research Report
  • [Book] WELCOME TOゲノムワールド ゲノム創薬科学最前線2009

    • Author(s)
      杉浦麗子
    • Total Pages
      264
    • Publisher
      京都廣川書店
    • Related Report
      2009 Annual Research Report
  • [Book] Sourcebook of Models for Biomedical Research 他2件2008

    • Author(s)
      Shunji Ishiwata, Takayoshi Kuno, Hirofumi Takada, Atsushi Koike, Reiko Sugiura.
    • Publisher
      Humana Press Inc.
    • Related Report
      2010 Self-evaluation Report
  • [Remarks]

    • URL

      http://www.phar.kindai.ac.jp/genome/

    • Related Report
      2012 Final Research Report
  • [Remarks] 近畿大学 薬学部 分子医療・ゲノム創薬学研究室

    • URL

      http://www.phar.kindai.ac.jp/genome/

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://www.phar.kindai.ac.jp/genome/

    • Related Report
      2011 Annual Research Report
  • [Remarks] ホームページ

    • URL

      http://www.phar.kindai.ac.jp/genome/

    • Related Report
      2010 Self-evaluation Report
  • [Remarks]

    • URL

      http://www.phar.kindai.ac.jp/genome/

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.phar.kindai.ac.jp/genome/

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.phar.kindai.ac.jp/genome/

    • Related Report
      2008 Annual Research Report
  • [Patent(Industrial Property Rights)] 新規糖脂質グリコシド化合物およびその製法2011

    • Inventor(s)
      杉浦麗子
    • Industrial Property Rights Holder
      近畿大学
    • Industrial Property Number
      2011-119297
    • Filing Date
      2011-05-27
    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] 容器用封止具2011

    • Inventor(s)
      石渡俊二
    • Industrial Property Rights Holder
      近畿大学
    • Filing Date
      2011-07-01
    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] 抗がん剤2011

    • Inventor(s)
      杉浦麗子
    • Industrial Property Rights Holder
      近畿大学、株式会社ダイアベティム
    • Industrial Property Number
      2011-261714
    • Filing Date
      2011-11-30
    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] mRNA発現を指標にしたMAPキナーゼシグナリングのリアルタイム測定法の開発と抗がん剤探索法2010

    • Inventor(s)
      杉浦麗子、高田宏文、石渡俊二、喜多綾子
    • Industrial Property Rights Holder
      学校法人近畿大学
    • Industrial Property Number
      2010-162093
    • Filing Date
      2010-07-16
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 注射剤の調製実習用教材およびそれを用いた調製実習方法2010

    • Inventor(s)
      石渡俊二
    • Industrial Property Rights Holder
      近畿大学、株式会社ルミカ
    • Filing Date
      2010-09-27
    • Related Report
      2010 Annual Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] mRNA発現を指標にしたMAPキナーゼシグナリングのリアルタイム測定法の開発と抗がん剤探索法2010

    • Inventor(s)
      杉浦麗子
    • Industrial Property Rights Holder
      近畿大学
    • Industrial Property Number
      2009-207005
    • Filing Date
      2010-07-16
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] 容器用封止具2010

    • Inventor(s)
      石渡俊二
    • Industrial Property Rights Holder
      近畿大学
    • Filing Date
      2010-06-25
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] 容器用封止具2010

    • Inventor(s)
      石渡俊二
    • Industrial Property Rights Holder
      近畿大学
    • Filing Date
      2010-06-25
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] 容器用封止具2010

    • Inventor(s)
      石渡俊二
    • Industrial Property Rights Holder
      近畿大学
    • Filing Date
      2010-07-06
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] キャピラリー電気泳動による核酸-タンパク質の結合解析法2009

    • Inventor(s)
      杉浦麗子、多賀淳、石渡俊二、佐藤亮介
    • Industrial Property Rights Holder
      学校法人近畿大学
    • Industrial Property Number
      2009-207005
    • Filing Date
      2009-09-08
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] キャピラリー電気泳動による核酸-タンパク質の結合解析法2009

    • Inventor(s)
      杉浦麗子、多賀淳、石渡俊二、佐藤亮介
    • Industrial Property Rights Holder
      学校法人近畿大学
    • Filing Date
      2009-09-08
    • Related Report
      2010 Self-evaluation Report
  • [Patent(Industrial Property Rights)] キャピラリー電気泳動による核酸-タンパク質の結合解析法2009

    • Inventor(s)
      杉浦麗子
    • Industrial Property Rights Holder
      学校法人近畿大学
    • Industrial Property Number
      2009-207005
    • Filing Date
      2009-09-08
    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 注射剤の調製実習用教材およびそれを用いた調製実習方法2009

    • Inventor(s)
      石渡俊二
    • Industrial Property Rights Holder
      学校法人近畿大学、株式会社ルミカ
    • Industrial Property Number
      2009-249404
    • Filing Date
      2009-10-29
    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 容器用封止具2009

    • Inventor(s)
      石渡俊二
    • Industrial Property Rights Holder
      学校法人近畿大学
    • Filing Date
      2009-11-10
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2018-03-28  

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